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Clinical Consequences and Management of Hypomagnesemia

Kevin J. Martin^*, Esther A. González^* and Eduardo Slatopolsky

*Division of Nephrology, Saint Louis University, and
Renal Division, Washington University, St. Louis, Missouri

Correspondence: Dr. Eduardo Slatopolsky, Washington University School of Medicine, Renal Division, 660 S. Euclid, Box 8126, St. Louis, MO 63110. Phone: 314-362-7208; Fax: 314-362-7875; E-mail: eslatopo{at}im.wustl.edu

Magnesium deficiency and hypomagnesemia remain quite prevalent, particularly in patients in intensive care units, and may have important clinical consequences. Magnesium should be measured directly in clinical circumstances in which a risk for magnesium deficiency exists and appropriately corrected when found. This commentary reviews the current knowledge of magnesium homeostasis and the risk factors and clinical consequences of magnesium deficiency and outlines approaches to therapy.

Copyright © 2009 by the American Society of Nephrology. Online ISSN: 1533-3450 Print ISSN: 1046-6673