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This Article Full Text Full Text (PDF) All Versions of this Article: ASN.2009040366v1 20/11/2441    most recent Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Google Scholar Articles by Strijack, B. Articles by Rigatto, C. PubMed PubMed Citation Articles by Strijack, B. Articles by Rigatto, C. Related Collections Related Article

Outcomes of Chronic Dialysis Patients Admitted to the Intensive Care Unit

Bradford Strijack^*, Julie Mojica, Manish Sood^*,,, Paul Komenda^*,,, Joe Bueti^*,,, Martina Reslerova^*,,, Dan Roberts^*, and Claudio Rigatto^*,,

*Department of Internal Medicine,
Intensive Care Program, and
Section of Nephrology, University of Manitoba, Winnipeg, Manitoba, Canada; and
Manitoba Renal Program, Winnipeg, Manitoba, Canada

Correspondence: Dr. Claudio Rigatto, University of Manitoba, 409 Tache Avenue, Winnipeg, Manitoba, R2H 2A6, Canada. Phone: 204-237-2121; Fax: 204-233-2770; E-mail: crigatto{at}sbgh.mb.ca

Received for publication April 6, 2009. Accepted for publication July 23, 2009.

Admission rates and outcomes of patients who have ESRD and are admitted to an intensive care unit (ICU) are not well defined. We conducted a historical cohort study using a prospective regional ICU database that captured all 11 adult ICUs in Winnipeg, Canada. Between 2000 and 2006, there were 34,965 total admissions to the ICU, 1173 (3.4%) of which were patients with ESRD. The main admission diagnoses among patients with ESRD were cardiac disease (31%), sepsis (15%), and arrest (10%). Compared with other patients in the ICU, those with ESRD were significantly younger but had more diabetes, peripheral arterial disease, and higher APACHE II (Acute Physiology and Chronic Health Evaluation II) scores; mean length of stay in the ICU was similar, however, between these two groups. Restricting the analysis to first admissions to the ICU, unadjusted in-hospital mortality was higher for patients with ESRD (16 versus 11%; P < 0.0001), but this difference did not persist after adjustment for baseline illness severity. In conclusion, although ESRD associates with increased mortality among patients who are admitted to the ICU, this effect is mostly a result of comorbidity.

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				P. M. Palevsky and S. D. Weisbord Critical Care Nephrology: It's Not Just Acute Kidney Injury J. Am. Soc. Nephrol., November 1, 2009; 20(11): 2281 - 2282. [Full Text] [PDF]

Copyright © 2009 by the American Society of Nephrology. Online ISSN: 1533-3450 Print ISSN: 1046-6673