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Journal of the American Society of Nephrology, Vol 3, 157-161, Copyright © 1992 by American Society of Nephrology

REVIEWS

Growth hormone and the kidney: a case presentation and review of the literature

MH O'Shea and DT Layish
Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.

Hypersomatotropism is accompanied by a significant increase in GFR and RPF. A case of a patient with acromegaly and supranormal renal function as measured by inulin and p-aminohippurate clearances is reported. The literature regarding the effects of growth hormone on renal function is reviewed, and the potential mechanisms of action and therapeutic implications of these effects are discussed.


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