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Journal of the American Society of Nephrology, Vol 4, 1754-1759, Copyright © 1994 by American Society of Nephrology

REGULAR ARTICLES

Abnormal endocrine tests in a hemodialysis patient

LA Hochstetler, MJ Flanigan and VS Lim
Department of Internal Medicine, University of Iowa College of Medicine, Iowa City 52242.

A home hemodialysis patient with abnormal thyroid function tests and hyperprolactinemia is presented. Abnormal thyroid tests included low total triiodothyronine and low total thyroxine and free thyroxine; the latter was documented by the use of both RIA and direct dialysis equilibrium techniques. Serum thyroid-stimulating hormone was normal, and the thyroid-stimulating hormone response to thyrotropin-releasing hormone stimulation was in the low-normal range. Serum prolactin was elevated to more than twice the normal level, and the prolactin response to thyrotropin-releasing hormone was also blunted. The interpretation, pathogenesis, physiologic significance, and management of these abnormalities are discussed.




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Copyright © 2008 by the American Society of Nephrology. Online ISSN: 1533-3450 Print ISSN: 1046-6673