Journal of the American Society of Nephrology
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Journal of the American Society of Nephrology, Vol 5, 153-160, Copyright © 1994 by American Society of Nephrology


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Myoglobinuric acute renal failure in a cardiac transplant patient taking lovastatin and cyclosporine

DS Alejandro and J Petersen
Division of Nephrology, Stanford University School of Medicine, CA 94305-5114.

Acute renal failure can occur in cardiac transplant patients for a variety of reasons. A case of a patient who developed acute renal failure secondarily to drug-induced rhabdomyolysis is reported. The literature regarding acute renal failure and lovastatin and other 3- hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors is reviewed. The potential mechanisms of myoglobinuria and nephrotoxicity and the therapeutic implications are discussed.


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J Am Board Fam MedHome page
L. L. Qiu, P. Nalin, Q. Huffman, J. B. Sneed, S. Renshaw, and S. W. Hartman
Nontraumatic Rhabdomyolysis with Long-Term Alcohol Intoxication
J Am Board Fam Med, January 1, 2004; 17(1): 54 - 58.
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