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Journal of the American Society of Nephrology, Vol 7, 2056-2061, Copyright © 1996 by American Society of Nephrology

REVIEWS

Severe hyperphosphatemia and hypocalcemia: a dilemma in patient management

M Sutters, CL Gaboury and WM Bennett
Division of Nephrology, Hypertension and Clinical Pharmacology, Oregon Health Sciences University, Portland, USA.

In the following report, a case of severe hyperphosphatemia and tetanic hypocalcemia resulting from the inadvertent oral ingestion of a phosphate enema is described. The physiology of serum phosphate regulation and the mechanism by which the elevation of serum phosphate is thought to induce hypocalcemia is discussed, and the treatment of hyperphosphatemia is reviewed. Finally, the potential consequences of the administration of calcium to treat tetany in a patient with severe hyperphosphatemia are considered.


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