REGULAR ARTICLES:

Cell Biology and Structure:

NS-398 Upregulates Constitutive Cyclooxygenase-2 Expression in the M-1 Cortical Collecting Duct Cell Line

SHAWN FERGUSON, RICHARD L. HÉBERT, and ODETTE LANEUVILLE

J Am Soc Nephrol 10: 2261-2271. [Abstract] [Full Text]  

Hemodynamics, Hypertension, and Vascular Regulation:

Zonal Heterogeneity in Action of Angiotensin-Converting Enzyme Inhibitor on Renal Microcirculation: Role of Intrarenal Bradykinin

HIROTO MATSUDA, KOICHI HAYASHI, KOKI ARAKAWA, MAREO NAITOH, EIJI KUBOTA, MASANORI HONDA, AKIRA MATSUMOTO, HIROMICHI SUZUKI, TOKUNORI YAMAMOTO, FUMIHIKO KAJIYA, and TAKAO SARUTA

J Am Soc Nephrol 10: 2272-2282. [Abstract] [Full Text]  

Increased Nitric Oxide Synthase-3 Expression in Kidneys of Deoxycorticosterone Acetate-Salt Hypertensive Rats

GRAHAM H. ALLCOCK, MIKA HUKKANEN, JULIA M. POLAK, JENNIFER S. POLLOCK, and DAVID M. POLLOCK

J Am Soc Nephrol 10: 2283-2289. [Abstract] [Full Text]  

Hormones, Growth Factors, and Cell Signaling:

Bioflavonoid Quercetin Inhibits Interleukin-1-Induced Transcriptional Expression of Monocyte Chemoattractant Protein-1 in Glomerular Cells via Suppression of Nuclear Factor-B

YOSHIHISA ISHIKAWA, HITOSHI SUGIYAMA, ELENI STYLIANOU, and MASANORI KITAMURA

J Am Soc Nephrol 10: 2290-2296. [Abstract] [Full Text]  

ATP Depletion Increases Tyrosine Phosphorylation of ß-Catenin and Plakoglobin in Renal Tubular Cells

JOHN H. SCHWARTZ, THEODORA SHIH, SARAH A. MENZA, and WILFRED LIEBERTHAL

J Am Soc Nephrol 10: 2297-2305. [Abstract] [Full Text]  

Secretion of Platelet-Activating Factor Is Mediated by MDR1 P-Glycoprotein in Cultured Human Mesangial Cells

SYLVAIN ERNEST and ELSA BELLO-REUSS

J Am Soc Nephrol 10: 2306-2313. [Abstract] [Full Text]  

Immunology and Pathology:

Chemokine and Chemokine Receptor Expression in a Novel Human Mesangial Cell Line

BERNHARD BANAS, BRUNO LUCKOW, MARCUS MÖLLER, CHRISTIANE KLIER, PETER J. NELSON, ERIK SCHADDE, MANFRED BRIGL, DANIEL HALEVY, HARRY HOLTHÖFER, BRIGITTE REINHART, and DETLEF SCHLÖNDORFF

J Am Soc Nephrol 10: 2314-2322. [Abstract] [Full Text]  

Complement Membrane Attack Complex (C5b-9) Mediates Interstitial Disease in Experimental Nephrotic Syndrome

MASAOMI NANGAKU, JEFF PIPPIN, and WILLIAM G. COUSER

J Am Soc Nephrol 10: 2323-2331. [Abstract] [Full Text]  

Identification of a Unique Glomerular Factor X Activator in Murine Lupus Nephritis

SUBODINI PERAMPALAM, LUOQUAN WANG, NANCY MYERS-MASON, JEN NEI YEOW, NIR STANIETSKY, JAMES PHILLIPS, JEFFREY I. WEITZ, CAMERON ACKERLEY, GARY A. LEVY, and EDWARD H. COLE

J Am Soc Nephrol 10: 2332-2341. [Abstract] [Full Text]  

Molecular Medicine, Genetics and Development:

Aberrant Splicing in the PKD2 Gene as a Cause of Polycystic Kidney Disease

DAVID M. REYNOLDS, TOMOHITO HAYASHI, YIQIANG CAI, BARBERA VELDHUISEN, TERRY J. WATNICK, XOSE M. LENS, TOSHIO MOCHIZUKI, FENG QIAN, YOSHIKO MAEDA, LI LI, RAGNHEIDUR FOSSDAL, ELIECER COTO, GUANQING WU, MARTIJN H. BREUNING, GREGORY G. GERMINO, DORIEN J. M. PETERS, and STEFAN SOMLO

J Am Soc Nephrol 10: 2342-2351. [Abstract] [Full Text]  

Primary Hyperoxaluria Type I: A Model for Multiple Mutations in aMonogenic Disease within a Distinct Ethnic Group

CHONI RINAT, RONALD J. A. WANDERS, ALFRED DRUKKER, DAVID HALLE, and YAACOV FRISHBERG

J Am Soc Nephrol 10: 2352-2358. [Abstract] [Full Text]  

Pathophysiology of Renal Disease:

Systemic Factors Are Involved in the Pathogenesis of Proteinuria-Induced Glomerulosclerosis in Adriamycin Nephrotic Rats

ERIC DE BOER, GERJAN NAVIS, ANTON T. M. TIEBOSCH, PAUL E. DE JONG, and DICK DE ZEEUW

J Am Soc Nephrol 10: 2359-2366. [Abstract] [Full Text]  

Nutrition and Chronic Renal Failure in Rats: What Is an OptimalDietary Protein?

CHRISTIANE L. MEIRELES, S. RUSS PRICE, ALINE M. L. PEREIRA, JOÃO T. A. CARVALHAES, and WILLIAM E. MITCH

J Am Soc Nephrol 10: 2367-2373. [Abstract] [Full Text]  

Growth Hormone Receptor Antagonism Prevents Early Renal in Nonobese Diabetic Mice

YAEL SEGEV, DANIEL LANDAU, RUTH RASCH, ALLAN FLYVBJERG, and MOSHE PHILLIP

J Am Soc Nephrol 10: 2374-2381. [Abstract] [Full Text]  

Clinical Nephrology:

The Paradox of the Low-Renin State in Diabetic Nephropathy

DEBORAH A. PRICE, LISA E. PORTER, MICHAEL GORDON, NAOMI D. L. FISHER, JOSE MARIO F. DE'OLIVEIRA, LORI M. B. LAFFEL, DIANE R. PASSAN, GORDON H. WILLIAMS, and NORMAN K. HOLLENBERG

J Am Soc Nephrol 10: 2382-2391. [Abstract] [Full Text]  

Dialysis:

Pharmacokinetics of Novel Erythropoiesis Stimulating Protein Compared with Epoetin Alfa in Dialysis Patients

IAIN C. MACDOUGALL, STEPHEN J. GRAY, ORLAITH ELSTON, CORMAC BREEN, BARBARA JENKINS, JEFF BROWNE, and JOAN EGRIE

J Am Soc Nephrol 10: 2392-2395. [Abstract] [Full Text]  

BRIEF COMMUNICATIONS:

Acute Renal Failure after Cardiopulmonary Bypass Is Related to Decreased Serum Ferritin Levels

CONNIE L. DAVIS, ANNAMARIA T. KAUSZ, RICHARD A. ZAGER, EVAN D. KHARASCH, and RICHARD P. COCHRAN

J Am Soc Nephrol 10: 2396-2402. [Abstract] [Full Text]  

Serum from Hemodialysis Patients Inhibits Basal and Cytokine-Stimulated Tissue Factor Expression in Vitro

PAOLA MADERNA, PATRICK COLEMAN, CATHERINE GODSON, YVONNE M. O'MEARA, and HUGH R. BRADY

J Am Soc Nephrol 10: 2403-2406. [Abstract] [Full Text]  

Relationship between Erythropoietin and Chronic Heart Failure in Patients on Chronic Hemodialysis

JUNKO KUMAGAI, NORIAKI YORIOKA, HIDEKI KAWANISHI, MISAKI MORIISHI, YUTAKA KOMIYA, YUKITERU ASAKIMORI, NAOKO TAKAHASHI, and SHINICHIRO TSUCHIYA

J Am Soc Nephrol 10: 2407-2411. [Abstract] [Full Text]  

REVIEWS:

Acute Regulation of Proximal Tubule Apical Membrane Na/H Exchanger NHE-3: Role of Phosphorylation, Protein Trafficking, and RegulatoryFactors

ORSON W. MOE

J Am Soc Nephrol 10: 2412-2425. [Full Text]  

Dietary Protein Restriction and the Progression of Chronic Renal Disease: What Have All of the Results of the MDRD Study Shown?

ANDREW S. LEVEY, TOM GREENE, GERALD J. BECK, ARLENE W. CAGGIULA, JOHN W. KUSEK, LAWRENCE G. HUNSICKER, and SAULO KLAHR

J Am Soc Nephrol 10: 2426-2439. [Abstract] [Full Text]  

SCIENCE WATCH:

Unraveling the Mechanisms of Glomerular Ultrafiltration: Nephrin, aKey Component of the Slit Diaphragm

KARL TRYGGVASON

J Am Soc Nephrol 10: 2440-2445. [Full Text]  

DISEASE OF THE MONTH:

Anti-Glomerular Basement Membrane Disease

DAVID C. KLUTH and ANDREW J. REES

J Am Soc Nephrol 10: 2446-2453. [Full Text]  

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