REGULAR ARTICLES:

Cell Biology and Structure:

PTH-Induced Downregulation of the Type IIa Na/P_i-Cotransporter Is Independent of Known Endocytic Motifs

NATI HERNANDO, JUTKA FORGO, JÜRG BIBER, and HEINI MURER

J Am Soc Nephrol 11: 1961-1968. [Abstract] [Full Text]  

Effect of Glucose on Intercellular Junctions of Cultured Human Peritoneal Mesothelial Cells

TAKAFUMI ITO, NORIAKI YORIOKA, MASAO YAMAMOTO, KATSUKO KATAOKA, and MICHIO YAMAKIDO

J Am Soc Nephrol 11: 1969-1979. [Abstract] [Full Text]  

Cell and Transport Physiology:

Differential Expression of Individual UT-A Urea Transporter Isoforms in Rat Kidney

SERENA M. BAGNASCO, TAO PENG, YUSHI NAKAYAMA, and JEFF M. SANDS

J Am Soc Nephrol 11: 1980-1986. [Abstract] [Full Text]  

Localization of Inward Rectifier Potassium Channel Kir7.1 in the Basolateral Membrane of Distal Nephron and Collecting Duct

KAYOKO OOKATA, AKIHIRO TOJO, YOSHIRO SUZUKI, NOBUHIRO NAKAMURA, KENJIRO KIMURA, CHRISTOPHER S. WILCOX, and SHIGEHISA HIROSE

J Am Soc Nephrol 11: 1987-1994. [Abstract] [Full Text]  

Hemodynamics, Hypertension, and Vascular Regulation:

Deoxycorticosterone Suppresses the Effects of Losartan in Nitric Oxide—Deficient Hypertensive Rats

MARIA C. DE GRACIA, ANTONIO OSUNA, FRANCISCO O'VALLE, RAIMUNDO G. DEL MORAL, ROSEMARY WANGENSTEEN, CIPRIANO GARCIA DEL RIO, and FELIX VARGAS

J Am Soc Nephrol 11: 1995-2000. [Abstract] [Full Text]  

Opposing Effects of Angiotensin II on Muscle and Renal Blood Flow under Euglycemic Conditions

DANILO FLISER, RALF DIKOW, SADRI DEMUKAJ, and EBERHARD RITZ

J Am Soc Nephrol 11: 2001-2006. [Abstract] [Full Text]  

Hormones, Growth Factors, and Cell Signaling:

AP-1 Proteins Mediate Hyperglycemia-Induced Activation of the Human TGF-ß1 Promoter in Mesangial Cells

CORA WEIGERT, ULRICH SAUER, KATRIN BRODBECK, ANDREAS PFEIFFER, HANS U. HÄRING, and ERWIN D. SCHLEICHER

J Am Soc Nephrol 11: 2007-2016. [Abstract] [Full Text]  

Leptospira Outer Membrane Protein Activates NF-B and Downstream Genes Expressed in Medullary Thick Ascending Limb Cells

CHIH-WEI YANG, MAI-SZU WU, MING-JENG PAN, JENN-JYE HONG, CHUN-CHEN YU, ALAIN VANDEWALLE, and CHIU-CHING HUANG

J Am Soc Nephrol 11: 2017-2026. [Abstract] [Full Text]  

Pathophysiology:

JB3, an IGF-I Receptor Antagonist, Inhibits Early Renal Growth in Diabetic and Uninephrectomized Rats

JOHN HAYLOR, HELEN HICKLING, EMAN EL ETER, ARTHUR MOIR, SIMON OLDROYD, COLIN HARDISTY, and A. MEGUID EL NAHAS

J Am Soc Nephrol 11: 2027-2035. [Abstract] [Full Text]  

Immunology and Pathology:

Glomerular Monocyte-Macrophage Features in ANCA-Positive Renal Vasculitis and Cryoglobulinemic Nephritis

MARIA PIA RASTALDI, FRANCO FERRARIO, ANDOR CRIPPA, GIACOMO DELL'ANTONIO, DONATELLA CASARTELLI, CARLO GRILLO, and GIUSEPPE D'AMICO

J Am Soc Nephrol 11: 2036-2043. [Abstract] [Full Text]  

Interleukin-17 and CD40-Ligand Synergistically Enhance Cytokine and Chemokine Production by Renal Epithelial Cells

ANDREA M. WOLTMAN, SIMONE DE HAIJ, JOKE G. BOONSTRA, SAM J.P. GOBIN, MOHAMED R. DAHA, and CEES VAN KOOTEN

J Am Soc Nephrol 11: 2044-2055. [Abstract] [Full Text]  

Molecular Medicine, Genetics and Development:

Rats Transgenic for Human Renin and Human Angiotensinogen as a Model for Gestational Hypertension

JÜRGEN BOHLENDER, DETLEV GANTEN, and FRIEDRICH C. LUFT

J Am Soc Nephrol 11: 2056-2061. [Abstract] [Full Text]  

Polymorphism of Angiotensin Converting Enzyme, Angiotensinogen, and Angiotensin II Type 1 Receptor Genes and End-Stage Renal Failure in IgA Nephropathy: IGARAS—A Study of 274 Men

LUC FRIMAT, CHRISTOPHE PHILIPPE, MARIE-NOËLLE MAGHAKIAN, PHILIPPE JONVEAUX, BRUNO HURAULT DE LIGNY, FRANCIS GUILLEMIN, and MICHÈLE KESSLER

J Am Soc Nephrol 11: 2062-2067. [Abstract] [Full Text]  

Evidence of Gene—Gene Interactions in the Genetic Susceptibility to Renal Impairment after Unilateral Nephrectomy

MASAHIDE SHIOZAWA, ABRAHAM P. PROVOOST, RICHARD P. E. VAN DOKKUM, REBECCA R. MAJEWSKI, and HOWARD J. JACOB

J Am Soc Nephrol 11: 2068-2078. [Abstract] [Full Text]  

Pathophysiology of Renal Disease:

Renal Epithelium Is a Previously Unrecognized Site of HIV-1 Infection

LESLIE A. BRUGGEMAN, MICHAEL D. ROSS, NOZOMU TANJI, ANDREA CARA, STEVEN DIKMAN, RONALD E. GORDON, GODFREY C. BURNS, VIVETTE D. D'AGATI, JONATHAN A. WINSTON, MARY E. KLOTMAN, and PAUL E. KLOTMAN

J Am Soc Nephrol 11: 2079-2087. [Abstract] [Full Text]  

Mineral Metabolism and Bone Disease:

Calcemic Activity of 19-Nor-1,25(OH)₂D₂ Decreases with Duration of Treatment

ALEX J. BROWN, JANE FINCH, FUMIAKI TAKAHASHI, and EDUARDO SLATOPOLSKY

J Am Soc Nephrol 11: 2088-2094. [Abstract] [Full Text]  

Clinical Nephrology:

Glomerular Permselectivity at the Onset of Nephropathy in Type 2 Diabetes Mellitus

KEVIN V. LEMLEY, KRISTINA BLOUCH, ISHA ABDULLAH, DEREK B. BOOTHROYD, PETER H. BENNETT, BRYAN D. MYERS, and ROBERT G. NELSON

J Am Soc Nephrol 11: 2095-2105. [Abstract] [Full Text]  

Dialysis:

Effects of Growth Hormone on Leptin Metabolism and Energy Expenditure in Hemodialysis Patients with Protein-Calorie Malnutrition

GIACOMO GARIBOTTO, ANTONINA BARRECA, ANTONELLA SOFIA, RODOLFO RUSSO, FULVIO FIORINI, GIORGIO CAPPELLI, FOSCO CAVATORTA, ARIANNA CESARONE, ROBERTO FRANCESCHINI, PAOLO SACCO, FRANCESCO MINUTO, and TOMASO BARRECA

J Am Soc Nephrol 11: 2106-2113. [Abstract] [Full Text]  

Interleukin-1 Receptor Antagonist Synthesis by Peripheral Blood Mononuclear Cells: A Novel Predictor of Morbidity among Hemodialysis Patients

VAIDYANATHAPURAM S. BALAKRISHNAN, CHRISTOPHER H. SCHMID, BERTRAND L. JABER, SVETLOZAR N. NATOV, ANDREW J. KING, and BRIAN J. G. PEREIRA

J Am Soc Nephrol 11: 2114-2121. [Abstract] [Full Text]  

Tunneled-Cuffed Catheter Associated Infections in Hemodialysis Patients Who Are Seropositive for the Human Immunodeficiency Virus

MICHELE H. MOKRZYCKI, BERND SCHRÖPPEL, GERO VON GERSDORFF, HEATHER RUSH, MIROSLAW P. ZDUNEK, and ROBERT FEINGOLD

J Am Soc Nephrol 11: 2122-2127. [Abstract] [Full Text]  

BRIEF COMMUNICATIONS:

Detection of Na⁺ Transporter Proteins in Urine

J. ANDREW McKEE, SHAILESH KUMAR, CAROLYN A. ECELBARGER, PATRICIA FERNÁNDEZ-LLAMA, JAMES TERRIS, and MARK A. KNEPPER

J Am Soc Nephrol 11: 2128-2132. [Abstract] [Full Text]  

Desensitization of Soluble Guanylate Cyclase in Renal Cortex during Endotoxemia in Mice

MLADEN KNOTEK, MATTHEW ESSON, PATRICIA GENGARO, CHARLES L. EDELSTEIN, and ROBERT W. SCHRIER

J Am Soc Nephrol 11: 2133-2137. [Abstract] [Full Text]  

SCIENCE WATCH:

The Immune Tolerance Network: The "Holy Grail" Comes to the Clinic

JEFFREY A. BLUESTONE, JEFFREY B. MATTHEWS, and ALAN M. KRENSKY

J Am Soc Nephrol 11: 2141-2146. [Full Text]  

DISEASE OF THE MONTH:

Malarial Acute Renal Failure

RASHAD S. BARSOUM

J Am Soc Nephrol 11: 2147-2154. [Full Text]  

MILESTONES IN NEPHROLOGY:

Endogenous Production of Fixed Acid and the Measurement of the Net Balance of Acid in Normal Subjects: [Relman AS, Lennon EJ, Lemann J, Jr.: J. Clin. Invest. 40:1621-1630, 1961 (with comments by Arnold S. Relman and Ira Kurtz)]

J Am Soc Nephrol 11: 2155-2164. [Full Text] [PDF]  

EDITORIALS:

HIV: Much at Stake with Kidneys?

JOHN P. MOORE and ROBERT W. DOMS

J Am Soc Nephrol 11: 2138-2140. [Full Text]  

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