REGULAR ARTICLES:

Cell and Transport Physiology:

Role of KCNE1-Dependent K⁺ Fluxes in Mouse Proximal Tubule

VOLKER VALLON, FLORIAN GRAHAMMER, KERSTIN RICHTER, MARKUS BLEICH, FLORIAN LANG, JACQUES BARHANIN, HARALD VÖLKL, and RICHARD WARTH

J Am Soc Nephrol 12: 2003-2011. [Abstract] [Full Text]  

Cationic Amino Acids Involved in Dicarboxylate Binding of the Flounder Renal Organic Anion Transporter

NATASCHA A. WOLFF, BETTINA GRÜNWALD, BJÖRN FRIEDRICH, FLORIAN LANG, STEFAN GODEHARDT, and GERHARD BURCKHARDT

J Am Soc Nephrol 12: 2012-2018. [Abstract] [Full Text]  

Diminished Renal Expression of Aquaporin Water Channels in Rats with Experimental Bilateral Ureteral Obstruction

SOO WAN KIM, SAM HYEON CHO, BONG SUK OH, CHUNG HO YEUM, KI CHUL CHOI, KYU YOUN AHN, and JONGUN LEE

J Am Soc Nephrol 12: 2019-2028. [Abstract] [Full Text]  

Gene Transfer of Transforming Growth Factor-ß1 to the Rat Peritoneum: Effects on Membrane Function

PETER J. MARGETTS, MARTIN KOLB, TOM GALT, CATHERINE M. HOFF, TY R. SHOCKLEY, and JACK GAULDIE

J Am Soc Nephrol 12: 2029-2039. [Abstract] [Full Text]  

Hemodynamics, Hypertension, and Vascular Regulation:

Remodeling of Resistance Arteries in Renal Failure: Effect of Endothelin Receptor Blockade

KERSTIN AMANN, GABRIEL MIL TENBERGER-MIL TENYI, AURELIA SIMONOVICIENE, ANDREAS KOCH, STEPHAN ORTH, and EBERHARD RITZ

J Am Soc Nephrol 12: 2040-2050. [Abstract] [Full Text]  

Vasopeptidase Inhibition Affords Greater Renoprotection than Angiotensin-Converting Enzyme Inhibition Alone

MAARTEN W. TAAL, VESSELIN D. NENOV, WAICHI WONG, SHARAD R. SATYAL, OLGA SAKHAROVA, JEONG HOON CHOI, JULIA L. TROY, and BARRY M. BRENNER

J Am Soc Nephrol 12: 2051-2059. [Abstract] [Full Text]  

Immunology and Pathology:

Podocyte Bridges between the Tuft and Bowman's Capsule: An Early Event in Experimental Crescentic Glomerulonephritis

MICHEL LE HIR, CORNELIA KELLER, VALÉRIE ESCHMANN, BRUNHILDE HÄHNEL, HILTRAUDE HOSSER, and WILHELM KRIZ

J Am Soc Nephrol 12: 2060-2071. [Abstract] [Full Text]  

Molecular Medicine, Genetics, and Development:

AGXT Gene Mutations and Their Influence on Clinical Heterogeneity of Type 1 Primary Hyperoxaluria

ANTONIO AMOROSO, DOROTI PIRULLI, FIORELLA FLORIAN, DANIELA PUZZER, MICHELE BONIOTTO, SERGIO CROVELLA, SILVIA ZEZLINA, ANDREA SPANÒ, GINA MAZZOLA, SILVANA SAVOLDI, CRISTINA FERRETTINI, SILVIA BERUTTI, MICHELE PETRARULO, and MARTINO MARANGELLA

J Am Soc Nephrol 12: 2072-2079. [Abstract] [Full Text]  

Pathophysiology of Renal Disease:

Pentosan Polysulfate Prevents Glomerular Hypertension and Structural Injury Despite Persisting Hypertension in 5/6 Nephrectomy Rats

NORMA A. BOBADILLA, IVAN TACK, EDILIA TAPIA, LAURA G. SÁNCHEZ-LOZADA, JOSÉ SANTAMARÍA, FABIOLA JIMÉNEZ, LILIANE J. STRIKER, GARY E. STRIKER, and JAIME HERRERA-ACOSTA

J Am Soc Nephrol 12: 2080-2087. [Abstract] [Full Text]  

Protective Role of Nitric Oxide in a Model of Thrombotic Microangiopathy in Rats

JING SHAO, TOSHIO MIYATA, KOEI YAMADA, NORIO HANAFUSA, TAKEHIKO WADA, KATHERINE L. GORDON, REIKO INAGI, KIYOSHI KUROKAWA, TOSHIRO FUJITA, RICHARD J. JOHNSON, and MASAOMI NANGAKU

J Am Soc Nephrol 12: 2088-2097. [Abstract] [Full Text]  

Aminoguanidine Ameliorates Overexpression of Prosclerotic Growth Factors and Collagen Deposition in Experimental Diabetic Nephropathy

DARREN J. KELLY, RICHARD E. GILBERT, ALISON J. COX, TINA SOULIS, GEORGE JERUMS, and MARK E. COOPER

J Am Soc Nephrol 12: 2098-2107. [Abstract] [Full Text]  

Mineral Metabolism and Bone Disease:

Effects of Urinary Macromolecules on Hydroxyapatite Crystal Formation

ANN M. BESHENSKY, JEFFREY A. WESSON, ELAINE M. WORCESTER, ELENA J. SOROKINA, CARL J. SNYDER, and JACK G. KLEINMAN

J Am Soc Nephrol 12: 2108-2116. [Abstract] [Full Text]  

Clinical Nephrology:

Diabetes Mellitus, Aortic Stiffness, and Cardiovascular Mortality in End-Stage Renal Disease

TETSUO SHOJI, MASANORI EMOTO, KAYO SHINOHARA, RYUSUKE KAKIYA, YOSHIHIRO TSUJIMOTO, HIROSHI KISHIMOTO, EIJI ISHIMURA, TSUTOMU TABATA, and YOSHIKI NISHIZAWA

J Am Soc Nephrol 12: 2117-2124. [Abstract] [Full Text]  

Defective Nitric Oxide Production and Functional Renal Reserve in Patients with Type 2 Diabetes Who Have Microalbuminuria of African and Asian Compared with White Origin

KENNETH ANTHONY EARLE, SEEMA MEHROTRA, RAYMOND NEIL DALTON, ELIZABETH DENVER, and RAMASAMYIYER SWAMINATHAN

J Am Soc Nephrol 12: 2125-2130. [Abstract] [Full Text]  

Dialysis:

Association of Elevated Serum PO₄, Ca x PO₄ Product, and Parathyroid Hormone with Cardiac Mortality Risk in Chronic Hemodialysis Patients

SANTHI K. GANESH, AUSTIN G. STACK, NATHAN W. LEVIN, TEMPIE HULBERT-SHEARON, and FRIEDRICH K. PORT

J Am Soc Nephrol 12: 2131-2138. [Abstract] [Full Text]  

Increasing Peritoneal Contact Area During Dialysis Improves Mass Transfer

MICHAEL F. FLESSNER, JOANNE LOFTHOUSE, and ANGELA WILLIAMS

J Am Soc Nephrol 12: 2139-2145. [Abstract] [Full Text]  

Chronic Uremia Induces Permeability Changes, Increased Nitric Oxide Synthase Expression, and Structural Modifications in the Peritoneum

SOPHIE COMBET, MARIE-LAURE FERRIER, MIEKE VAN LANDSCHOOT, MARIA STOENOIU, PIERRE MOULIN, TOSHIO MIYATA, NORBERT LAMEIRE, and OLIVIER DEVUYST

J Am Soc Nephrol 12: 2146-2157. [Abstract] [Full Text]  

Relative Contribution of Residual Renal Function and Peritoneal Clearance to Adequacy of Dialysis: A Reanalysis of the CANUSA Study

JOANNE M. BARGMAN, KEVIN E. THORPE, and DAVID N. CHURCHILL

J Am Soc Nephrol 12: 2158-2162. [Abstract] [Full Text]  

Transplantation:

Long-Term Results of a Randomized Study Comparing Three Immunosuppressive Schedules with Cyclosporine in Cadaveric Kidney Transplantation

GIUSEPPE MONTAGNINO, ANTONIO TARANTINO, GIUSEPPE P. SEGOLONI, VINCENZO CAMBI, GAETANO RIZZO, PAOLO ALTIERI, MARCO CASTAGNETO, MAURIZIO SALVADORI, MARIA COSSU, FRANCESCO PISANI, MARIO CARMELLINI, FRANCESCO MASTRANGELO, ROBERTO FERRARA, and CLAUDIO PONTICELLI

J Am Soc Nephrol 12: 2163-2169. [Abstract] [Full Text]  

BRIEF COMMUNICATIONS:

Characterization of a Putative Founder Mutation that Accounts for the High Incidence of Cystinosis in Brittany

VASILIKI KALATZIS, STÉPHANIE CHERQUI, GENEVIÈVE JEAN, BÉATRICE CORDIER, PIERRE COCHAT, MICHEL BROYER, and CORINNE ANTIGNAC

J Am Soc Nephrol 12: 2170-2174. [Abstract] [Full Text]  

Hepatocyte Nuclear Factor-1ß: A New Kindred with Renal Cysts and Diabetes and Gene Expression in Normal Human Development

MARIA KOLATSI-JOANNOU, CORALIE BINGHAM, SIAN ELLARD, MICHAEL P. BULMAN, LISA I. S. ALLEN, ANDREW T. HATTERSLEY, and ADRIAN S. WOOLF

J Am Soc Nephrol 12: 2175-2180. [Abstract] [Full Text]  

REVIEWS:

The Kidney and Homocysteine Metabolism

ALLON N. FRIEDMAN, ANDREW G. BOSTOM, JACOB SELHUB, ANDREW S. LEVEY, and IRWIN H. ROSENBERG

J Am Soc Nephrol 12: 2181-2189. [Abstract] [Full Text]  

DISEASE OF THE MONTH:

Atherosclerotic Renal Artery Stenosis: To Treat Conservatively, to Dilate, to Stent, or to Operate?

PIERRE-FRANÇOIS PLOUIN, PATRICK ROSSIGNOL, and GUILLAUME BOBRIE

J Am Soc Nephrol 12: 2190-2196. [Full Text]  

MILESTONES IN NEPHROLOGY:

Free-Flow Potential Profile along Rat Kidney Proximal Tubule: [Fromter E, GeBner K: Pflugers. Arch. 351: 69-83, 1974 (with comments by Eberhard Fromter and Emile L. Boulpaep)]

J Am Soc Nephrol 12: 2197-2206. [Full Text]  

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