ARTICLES:

Cell Biology and Structure:

Cellular Distribution and Function of Soluble Guanylyl Cyclase in Rat Kidney and Liver

FRANZISKA THEILIG, MAGDALENA BOSTANJOGLO, HERMANN PAVENSTÄDT, CLEMENS GRUPP, GUDRUN HOLLAND, ILKA SLOSAREK, AXEL M. GRESSNER, MICHAEL RUSSWURM, DORIS KOESLING, and SEBASTIAN BACHMANN

J Am Soc Nephrol 12: 2209-2220. [Abstract] [Full Text]  

Cell and Transport Physiology:

Hydration Status Affects Nuclear Distribution of Transcription Factor Tonicity Responsive Enhancer Binding Protein in Rat Kidney

JUNG H. CHA, SEUNG KYOON WOO, KI H. HAN, YOUNG H. KIM, JOSEPH S. HANDLER, JIN KIM, and H. MOO KWON

J Am Soc Nephrol 12: 2221-2230. [Abstract] [Full Text]  

Downstream Shift in Sodium Pump Activity along the Nephron during Acute Hypertension

CLARA E. MAGYAR, YIBIN ZHANG, NIELS-H. HOLSTEIN-RATHLOU, and ALICIA A. MCDONOUGH

J Am Soc Nephrol 12: 2231-2240. [Abstract] [Full Text]  

Increased Synthesis and AVP Unresponsiveness of Na,K-ATPase in Collecting Duct from Nephrotic Rats

GEORGES DESCHÊNES, SANDRINE GONIN, EINATH ZOLTY, LYDIE CHEVAL, MARTINE ROUSSELOT, PIERRE-YVES MARTIN, JEAN-MARC VERBAVATZ, ERIC FÉRAILLE, and ALAIN DOUCET

J Am Soc Nephrol 12: 2241-2252. [Abstract] [Full Text]  

Hemodynamics, Hypertension, and Vascular Regulation:

Time-Dependent Autoregulation of Renal Blood Flow in Conscious Rats

BERT FLEMMING, NICOLE ARENZ, ERDMANN SEELIGER, THOMAS WRONSKI, KATHARINA STEER, and PONTUS B. PERSSON

J Am Soc Nephrol 12: 2253-2262. [Abstract] [Full Text]  

Renal Cortical Vasoconstriction Contributes to Development of Salt-Sensitive Hypertension after Angiotensin II Exposure

MARTHA FRANCO, EDILIA TAPIA, JOSÉ SANTAMARÍA, IGNACIO ZAFRA, ROMEO GARCÍA-TORRES, KATHERINE L. GORDON, HÉCTOR PONS, BERNARDO RODRÍGUEZ-ITURBE, RICHARD J. JOHNSON, and JAIME HERRERA-ACOSTA

J Am Soc Nephrol 12: 2263-2271. [Abstract] [Full Text]  

Dopamine D₃ Receptors and Salt-Dependent Hypertension

GERD LUIPPOLD, CLAUDIA ZIMMERMANN, MATTHIAS MAI, DORIS KLOOR, DOROTHEA STARCK, GERHARD GROSS, and BERND MÜHLBAUER

J Am Soc Nephrol 12: 2272-2279. [Abstract] [Full Text]  

Vasopeptidase Inhibition Restores Renovascular Endothelial Dysfunction in Salt-Induced Hypertension

THOMAS QUASCHNING, LIVIUS V. D'USCIO, SIDNEY SHAW, HERMANN-JOSEF GRÖNE, FRANK RUSCHITZKA, and THOMAS F. LÜSCHER

J Am Soc Nephrol 12: 2280-2287. [Abstract] [Full Text]  

Hormones, Growth Factors, and Cell Signaling:

Activation of ß₂-Adrenoceptor Prevents Shiga Toxin 2-Induced TNF- Gene Transcription

AKIO NAKAMURA, EDWARD J. JOHNS, AKIRA IMAIZUMI, YUKISHIGE YANAGAWA, and TAKAO KOHSAKA

J Am Soc Nephrol 12: 2288-2299. [Abstract] [Full Text]  

Immunology and Pathology:

Effects of Retinoids on the TGF-ß System and Extracellular Matrix in Experimental Glomerulonephritis

CHRISTIAN MORATH, CLAUDIUS DECHOW, INGO LEHRKE, VOLKER HAXSEN, RÜDIGER WALDHERR, JÜRGEN FLOEGE, EBERHARD RITZ, and JÜRGEN WAGNER

J Am Soc Nephrol 12: 2300-2309. [Abstract] [Full Text]  

Interleukin-11 Attenuates Nephrotoxic Nephritis in Wistar Kyoto Rats

PING-CHIN LAI, H. TERENCE COOK, JENNIFER SMITH, JAMES C. KEITH, JR., CHARLES D. PUSEY, and FREDERICK W. K. TAM

J Am Soc Nephrol 12: 2310-2320. [Abstract] [Full Text]  

Renal Endothelin-1 and Endothelin Receptor Type B Expression in Glomerular Diseases with Proteinuria

INGO LEHRKE, RÜDIGER WALDHERR, EBERHARD RITZ, and JÜRGEN WAGNER

J Am Soc Nephrol 12: 2321-2329. [Abstract] [Full Text]  

Molecular Medicine, Genetics, and Development:

Inflamed Glomeruli—Specific Gene Activation that Uses Recombinant Adenovirus with the Cre/loxP System

TAKASHI YOKOO, TOYA OHASHI, YASUNORI UTSUNOMIYA, HIROAKI SHIBA, JIN SONG SHEN, YUTAKA HISADA, YOSHIKATSU ETO, TETSUYA KAWAMURA, and TATSUO HOSOYA

J Am Soc Nephrol 12: 2330-2337. [Abstract] [Full Text]  

Effect of Human OGG1 1245CG Gene Polymorphism on 8-Hydroxy-2'-Deoxyguanosine Levels of Leukocyte DNA among Patients Undergoing Chronic Hemodialysis

DER-CHERNG TARNG, TZUNG-JIUN TSAI, WEI-TING CHEN, TSUNG-YUN LIU, and YAU-HUEI WEI

J Am Soc Nephrol 12: 2338-2347. [Abstract] [Full Text]  

Familial Juvenile Hyperuricemic Nephropathy and Autosomal Dominant Medullary Cystic Kidney Disease Type 2: Two Facets of the Same Disease?

KARIN DAHAN, ARNO FUCHSHUBER, STAVROULA ADAMIS, MICHÈLE SMAERS, SABINE KROISS, GUY LOUTE, JEAN-PIERRE COSYNS, FRIEDHELM HILDEBRANDT, CHRISTINE VERELLEN-DUMOULIN, and YVES PIRSON

J Am Soc Nephrol 12: 2348-2357. [Abstract] [Full Text]  

Expression of the Type IV Collagenase System during Mouse Kidney Development and Tubule Segmentation

BRUNO LEGALLICIER, GERMAIN TRUGNAN, GILLIAN MURPHY, BRIGITTE LELONGT, and PIERRE RONCO

J Am Soc Nephrol 12: 2358-2369. [Abstract] [Full Text]  

Pathophysiology of Renal Disease:

Coexpressed Nitric Oxide Synthase and Apical ß₁ Integrins Influence Tubule Cell Adhesion after Cytokine-Induced Injury

PAUL A. GLYNNE, JOANNA PICOT, and THOMAS J. EVANS

J Am Soc Nephrol 12: 2370-2383. [Abstract] [Full Text]  

Role of Ceramide Synthase in Oxidant Injury to Renal Tubular Epithelial Cells

NORISHI UEDA, SIMONE M. R. CAMARGO, XIAOMAN HONG, ALEXEI G. BASNAKIAN, PATRICK D. WALKER, and SUDHIR V. SHAH

J Am Soc Nephrol 12: 2384-2391. [Abstract] [Full Text]  

Loss of Tubular Bone Morphogenetic Protein—7 in Diabetic Nephropathy

SHI-NONG WANG, JANINE LAPAGE, and RAIMUND HIRSCHBERG

J Am Soc Nephrol 12: 2392-2399. [Abstract] [Full Text]  

Mineral Metabolism and Bone Disease:

Intact IGF-Binding Protein-4 and -5 and Their Respective Fragments Isolated from Chronic Renal Failure Serum Differentially Modulate IGF-I Actions in Cultured Growth Plate Chondrocytes

DANIELA KIEPE, DENNIS L. ANDRESS, SUBBURAMAN MOHAN, LUDGER STÄNDKER, TIM ULINSKI, RAINER HIMMELE, OTTO MEHLS, and BURKHARD TÖNSHOFF

J Am Soc Nephrol 12: 2400-2410. [Abstract] [Full Text]  

Clinical Nephrology:

Survival and Development of Cardiovascular Disease by Modality of Treatment in Patients with End-Stage Renal Disease

FRANCESCO LOCATELLI, DANIELE MARCELLI, FERRUCCIO CONTE, MARCO D'AMICO, LUCIA DEL VECCHIO, AURELIO LIMIDO, FABIO MALBERTI, and DONATELLA SPOTTI

J Am Soc Nephrol 12: 2411-2417. [Abstract] [Full Text]  

Improved Growth in Young Children with Severe Chronic Renal Insufficiency Who Use Specified Nutritional Therapy

RULAN S. PAREKH, JOSEPH T. FLYNN, WILLIAM E. SMOYER, JOAN L. MILNE, DAVID B. KERSHAW, TIMOTHY E. BUNCHMAN, and AILEEN B. SEDMAN

J Am Soc Nephrol 12: 2418-2426. [Abstract] [Full Text] [Data Supplement]  

Sympathetic Activity Is Increased in Polycystic Kidney Disease and Is Associated with Hypertension

INGE H. H. T. KLEIN, GERRY LIGTENBERG, P. LIAM OEY, HEIN A. KOOMANS, and PETER J. BLANKESTIJN

J Am Soc Nephrol 12: 2427-2433. [Abstract] [Full Text]  

Dialysis:

Prolonged Exposure to Glucose Degradation Products Impairs Viability and Function of Human Peritoneal Mesothelial Cells

JANUSZ WITOWSKI, JUSTYNA WISNIEWSKA, KATARZYNA KORYBALSKA, THORSTEN O. BENDER, ANDRZEJ BREBOROWICZ, GERHARD M. GAHL, ULRICH FREI, JUTTA PASSLICK-DEETJEN, and ACHIM JÖRRES

J Am Soc Nephrol 12: 2434-2441. [Abstract] [Full Text]  

Acceleration of Neutrophil Apoptosis by Glucose-Containing Peritoneal Dialysis Solutions: Role of Caspases

MARINA PENÉLOPE CATALAN, ANA REYERO, JESÚS EGIDO, and ALBERTO ORTIZ

J Am Soc Nephrol 12: 2442-2449. [Abstract] [Full Text]  

Independent Effects of Residual Renal Function and Dialysis Adequacy on Actual Dietary Protein, Calorie, and Other Nutrient Intake in Patients on Continuous Ambulatory Peritoneal Dialysis

ANGELA YEE-MOON WANG, MANDY MAN-MEI SEA, RICKY IP, MAN-CHING LAW, KAI-MING CHOW, SIU-FAI LUI, PHILIP KAM-TAO LI, and JEAN WOO

J Am Soc Nephrol 12: 2450-2457. [Abstract] [Full Text]  

Prognostic Value of Ultrasonographic Measurement of Carotid Intima Media Thickness in Dialysis Patients

FRANCESCO ANTONIO BENEDETTO, FRANCESCA MALLAMACI, GIOVANNI TRIPEPI, and CARMINE ZOCCALI

J Am Soc Nephrol 12: 2458-2464. [Abstract] [Full Text]  

Death, Hospitalization, and Economic Associations among Incident Hemodialysis Patients with Hematocrit Values of 36 to 39%

ALLAN J. COLLINS, SUYING LI, WENDY ST. PETER, JIM EBBEN, TRICIA ROBERTS, JENNIE Z. MA, and WILLARD MANNING

J Am Soc Nephrol 12: 2465-2473. [Abstract] [Full Text]  

Transplantation:

Influence of Donor Brain Death on Chronic Rejection of Renal Transplants in Rats

JOHANN PRATSCHKE, MARKUS J. WILHELM, IGOR LASKOWSKI, MAMORU KUSAKA, FRANCISCA BEATO, STEFAN G. TULLIUS, PETER NEUHAUS, WAYNE W. HANCOCK, and NICHOLAS L. TILNEY

J Am Soc Nephrol 12: 2474-2481. [Abstract] [Full Text]  

C4d-Positive Acute Humoral Renal Allograft Rejection: Effective Treatment by Immunoadsorption

GEORG A. BÖHMIG, HEINZ REGELE, MARKUS EXNER, VICTOR DERHARTUNIAN, JOSEF KLETZMAYR, MARCUS D. SÄEMANN, WALTER H. HÖRL, WILFRED DRUML, and BRUNO WATSCHINGER

J Am Soc Nephrol 12: 2482-2489. [Abstract] [Full Text]  

Pancreas after Kidney Transplants in Posturemic Patients with Type I Diabetes Mellitus

ANGELIKA C. GRUESSNER, DAVID E. R. SUTHERLAND, DAVID L. DUNN, JOHN S. NAJARIAN, ABHI HUMAR, RAJA KANDASWAMY, and RAINER W. G. GRUESSNER

J Am Soc Nephrol 12: 2490-2499. [Abstract] [Full Text]  

BRIEF COMMUNICATIONS:

Indirect Allorecognition of Donor Class I and II Major Histocompatibility Complex Peptides Promotes the Development of Transplant Vasculopathy

KARL L. WOMER, JAMES R. STONE, BARBARA MURPHY, ANIL CHANDRAKER, and MOHAMED H. SAYEGH

J Am Soc Nephrol 12: 2500-2506. [Abstract] [Full Text]  

Renal Effects of Glibenclamide in Cystic Fibrosis Mice

JONATHAN KIBBLE, ANDREW NEAL, STANLEY WHITE, ROGER GREEN, STEVE EVANS, and CHRISTOPHER TAYLOR

J Am Soc Nephrol 12: 2507-2510. [Abstract] [Full Text]  

SCIENCE WATCH:

Role of Calcium-Phosphate Product and Bone-Associated Proteins on Vascular Calcification in Renal Failure

MARIO COZZOLINO, ADRIANA S. DUSSO, and EDUARDO SLATOPOLSKY

J Am Soc Nephrol 12: 2511-2516. [Full Text]  

DISEASE OF THE MONTH:

Simultaneous Pancreas-Kidney and Pancreas Transplantation

BRYAN N. BECKER, JON S. ODORICO, YOLANDA T. BECKER, MARILYN GROSHEK, CATHY WERWINSKI, JOHN D. PIRSCH, and HANS W. SOLLINGER

J Am Soc Nephrol 12: 2517-2527. [Full Text]  

MILESTONES IN NEPHROLOGY:

Cytochemical Observations on the Relationship Between Lysosomes and Phagosomes in Kidney and Liver by Combined Staining for Acid Phosphatase and Intravenously Injected Horseradish Peroxidase: [Straus W: J. Cell Biol. 20: 497-507, 1964 (with comments by Werner Straus and Erik Ilso Christensen)]

J Am Soc Nephrol 12: 2528-2537. [Full Text]  

EDITORIALS:

Why Is JASN So Big?

WILLIAM G. COUSER

J Am Soc Nephrol 12: 2538. [Full Text]  

SPECIAL TRIBUTE:

In Memoriam: A Commentary on R. Bernd Sterzel

DONTSCHO KERJASCHKI, ULRICH KUNTZENDORF, FRIEDRICH C. LUFT, JOHANNES F. E. MANN, HEINI MURER, ROLF STAHL, and MANFRED WEBER

J Am Soc Nephrol 12: 2539-2540. [Full Text]  

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