THIS MONTH'S HIGHLIGHTS:

This Month’s Highlights

J Am Soc Nephrol 13: A8-A9. [Full Text]  

ARTICLES:

Cell and Transport Physiology:

Sulfonylurea-Sensitive K⁺ Transport is Involved in Cl^- Secretion and Cyst Growth by Cultured ADPKD Cells

Lawrence P. Sullivan, Darren P. Wallace, Tony Gover, Paul A. Welling, Tamio Yamaguchi, Robin Maser, Jason W. Eppler, and Jared J. Grantham

J Am Soc Nephrol 13: 2619-2627. [Abstract] [Full Text]  

The Renal Na⁺-Dependent Dicarboxylate Transporter, NaDC-3, Translocates Dimethyl- and Disulfhydryl-Compounds and Contributes to Renal Heavy Metal Detoxification

Birgitta C. Burckhardt, Britta Drinkuth, Christine Menzel, Angela König, Jürgen Steffgen, Stephen H. Wright, and Gerhard Burckhardt

J Am Soc Nephrol 13: 2628-2638. [Abstract] [Full Text]  

Glomerular Endothelial Fenestrae In Vivo Are Not Formed from Caveolae

Jenny Sörensson, Wolfgang Fierlbeck, Torsten Heider, Karin Schwarz, David S. Park, Peter Mundel, Michael Lisanti, and Barbara J. Ballermann

J Am Soc Nephrol 13: 2639-2647. [Abstract] [Full Text]  

Hormones, Growth Factors, Cell Signaling, Cell Biology and Structure:

Discoidin Domain Receptor 1 Controls Growth and Adhesion of Mesangial Cells

Cyrile A. Curat and Wolfgang F. Vogel

J Am Soc Nephrol 13: 2648-2656. [Abstract] [Full Text]  

Inhibitory Smads and TGF- Signaling in Glomerular Cells

Mario Schiffer, Lena E. Schiffer, Arti Gupta, Andrey S. Shaw, Ian S.D. Roberts, Peter Mundel, and Erwin P. Böttinger

J Am Soc Nephrol 13: 2657-2666. [Abstract] [Full Text]  

Site-Specific Alteration of Actin Assembly Visualized in Living Renal Epithelial Cells during ATP Depletion

Eric A. Shelden, Joel M. Weinberg, Dorothy R. Sorenson, Chris A. Edwards, and Fiona M. Pollock

J Am Soc Nephrol 13: 2667-2680. [Abstract] [Full Text]  

Hemodynamics, Hypertension, and Vascular Regulation:

Abolition of Hypertension-Induced End-Organ Damage by Androgen Receptor Blockade in Transgenic Rats Harboring the Mouse Ren-2 Gene

Ovidiu Baltatu, Cécile Cayla, Radu Iliescu, Dmitrii Andreev, Cynthia Jordan, and Michael Bader

J Am Soc Nephrol 13: 2681-2687. [Abstract] [Full Text]  

Changes of Cell Volume and Nitric Oxide Concentration in Macula Densa Cells Caused by Changes in Luminal NaCl Concentration

Ruisheng Liu, János Pittner, and A. Erik G. Persson

J Am Soc Nephrol 13: 2688-2696. [Abstract] [Full Text]  

Immunology and Pathology:

Estimating Mean Glomerular Volume Using Two Arbitrary Parallel Sections

Behzad Najafian, John M. Basgen, and Michael Mauer

J Am Soc Nephrol 13: 2697-2705. [Abstract] [Full Text]  

Molecular Medicine, Genetics and Development:

Genetic Dissection of Increased Urinary Albumin Excretion in the Munich Wistar Frömter Rat

Angela Schulz, Andre Litfin, Peter Kossmehl, and Reinhold Kreutz

J Am Soc Nephrol 13: 2706-2714. [Abstract] [Full Text]  

Transcriptional Regulation of a Mesangium-Predominant Gene, Megsin

Reiko Inagi, Toshio Miyata, Masaomi Nangaku, Hiroshi Ueyama, Ken-ichi Takeyama, Shigeaki Kato, and Kiyoshi Kurokawa

J Am Soc Nephrol 13: 2715-2722. [Abstract] [Full Text]  

Pathophysiology of Renal Disease:

The Effect of Caffeine on Renal Epithelial Cells from Patients with Autosomal Dominant Polycystic Kidney Disease

Franck A. Belibi, Darren P. Wallace, Tamio Yamaguchi, Marcy Christensen, Gail Reif, and Jared J. Grantham

J Am Soc Nephrol 13: 2723-2729. [Abstract] [Full Text]  

Effects of Cigarette Smoking on Glomerular Structure and Function in Type 2 Diabetic Patients

Bruno Baggio, Alessandro Budakovic, Michele Dalla Vestra, Alois Saller, Marino Bruseghin, and Paola Fioretto

J Am Soc Nephrol 13: 2730-2736. [Abstract] [Full Text]  

2-Hydroxyestradiol Attenuates Renal Disease in Chronic Puromycin Aminonucleoside Nephropathy

Stevan P. Tofovic, Raghvendra Dubey, Eman M. Salah, and Edwin K. Jackson

J Am Soc Nephrol 13: 2737-2747. [Abstract] [Full Text]  

Plasma Ghrelin and Desacyl Ghrelin Concentrations in Renal Failure

Akihiro Yoshimoto, Kiyoshi Mori, Akira Sugawara, Masashi Mukoyama, Kensei Yahata, Takayoshi Suganami, Kazuhiko Takaya, Hiroshi Hosoda, Masayasu Kojima, Kenji Kangawa, and Kazuwa Nakao

J Am Soc Nephrol 13: 2748-2752. [Abstract] [Full Text]  

Preconditioning and Adenosine Protect Human Proximal Tubule Cells in an In Vitro Model of Ischemic Injury

H. Thomas Lee and Charles W. Emala

J Am Soc Nephrol 13: 2753-2761. [Abstract] [Full Text]  

Mineral Metabolism and Bone Disease:

The Severity of Secondary Hyperparathyroidism in Chronic Renal Insufficiency is GFR-Dependent, Race-Dependent, and Associated with Cardiovascular Disease

Ian H. de Boer, Irina Gorodetskaya, Belinda Young, Chi-yuan Hsu, and Glenn M. Chertow

J Am Soc Nephrol 13: 2762-2769. [Abstract] [Full Text]  

Dialysis:

Efficacy of Oral Sildenafil in Hemodialysis Patients with Erectile Dysfunction

Ivan Seibel, Carlos Eduardo Poli de Figueiredo, Cláudio Telöken, and João Feliz Moraes

J Am Soc Nephrol 13: 2770-2775. [Abstract] [Full Text]  

Epidemiology and Outcomes:

Blood Pressure and Decline in Kidney Function: Findings from the Systolic Hypertension in the Elderly Program (SHEP)

J. Hunter Young, Michael J. Klag, Paul Muntner, Joanna L. Whyte, Marco Pahor, and Josef Coresh

J Am Soc Nephrol 13: 2776-2782. [Abstract] [Full Text]  

BRIEF COMMUNICATIONS:

Iron Status and Hemoglobin Level in Chronic Renal Insufficiency

Chi-yuan Hsu, Charles E. McCulloch, and Gary C. Curhan

J Am Soc Nephrol 13: 2783-2786. [Abstract] [Full Text]  

DISEASE OF THE MONTH:

Acquired Ultrafiltration Dysfunction in Peritoneal Dialysis Patients

Peter J. Margetts and David N. Churchill

J Am Soc Nephrol 13: 2787-2794. [Full Text]  

REVIEWS:

Molecular Approaches to Urea Transporters

Jeff M. Sands

J Am Soc Nephrol 13: 2795-2806. [Abstract] [Full Text]  

EDITORIALS:

Gender and the Progression of Renal Disease

Joel Neugarten

J Am Soc Nephrol 13: 2807-2809. [Full Text]  

EDITOR-IN-CHIEF COMMENT:

Chronic Kidney Disease – How Many Have It?

William G. Couser

J Am Soc Nephrol 13: 2810. [Full Text]  

LETTER TO THE EDITOR:

Estimating the Prevalence of Low Glomerular Filtration Rate Requires Attention to the Creatinine Assay Calibration

Josef Coresh, Garabed Eknoyan, Andrew S. Levey, Catherine M. Clase, Amit X. Garg, and Bryce A Kiberd

J Am Soc Nephrol 13: 2811-2816. [Full Text]  

OVERVIEW:

Overview: As to Diseases, Make a Habit of Two Things — To Help, or at Least Do No Harm

William McClellan

J Am Soc Nephrol 13: 2817-2819. [Full Text]  

ANNOUNCEMENTS:

J Am Soc Nephrol 13: 2820-2821. [Full Text]  

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