THIS MONTH'S HIGHLIGHTS:

This Month's Highlights

J Am Soc Nephrol 13: A11-A12. [Full Text]  

ASN NEWS:

ASN News

J Am Soc Nephrol 13: A17-A20. [Full Text]  

NIDDK NEWS:

NIDDK News

J Am Soc Nephrol 13: A44-A45. [Full Text]  

ARTICLES:

Cell and Transport Physiology:

Secretory-Defect Distal Renal Tubular Acidosis Is Associated with Transporter Defect in H⁺-ATPase and Anion Exchanger-1

Jin Suk Han, Gheun-Ho Kim, Jin Kim, Un Sil Jeon, Kwon Wook Joo, Ki Young Na, Curie Ahn, Suhnggwon Kim, Sang Eun Lee, and Jung Sang Lee

J Am Soc Nephrol 13: 1425-1432. [Abstract] [Full Text]  

Rapid (24-Hour) Reaccumulation of Brain Organic Osmolytes (Particularly myo-Inositol) in Azotemic Rats after Correction of Chronic Hyponatremia

Alain Soupart, Stephen Silver, Barbara Schroöeder, Richard Sterns, and Guy Decaux

J Am Soc Nephrol 13: 1433-1441. [Abstract] [Full Text]  

Functional Expression of Mutations in the Human NaCl Cotransporter: Evidence for Impaired Routing Mechanisms in Gitelman’s Syndrome

Joke C. de Jong, Walter A. van der Vliet, Lambertus P. W. J. van den Heuvel, Peter H. G. M. Willems, Nine V. A. M. Knoers, and René J. M. Bindels

J Am Soc Nephrol 13: 1442-1448. [Abstract] [Full Text]  

Indomethacin Blocks Enhanced Paracellular Backflux in Proximal Tubules

Carla R. Ramsey, Theresa J. Berndt, and Franklyn G. Knox

J Am Soc Nephrol 13: 1449-1454. [Abstract] [Full Text]  

Hormones, Growth Factors, Cell Signaling, Cell Biology and Structure:

Identification of a Renal Proximal Tubular Cell-Specific Enhancer in the Mouse 25-Hydroxyvitamin D 1-Hydroxylase Gene

Tadashi Yoshida, Jun Yoshino, Matsuhiko Hayashi, and Takao Saruta

J Am Soc Nephrol 13: 1455-1463. [Abstract] [Full Text]  

Smad7 Inhibits Fibrotic Effect of TGF- on Renal Tubular Epithelial Cells by Blocking Smad2 Activation

Jin H. Li, Hong-Jian Zhu, Xiao R. Huang, Kar N. Lai, Richard J. Johnson, and Hui Y. Lan

J Am Soc Nephrol 13: 1464-1472. [Abstract] [Full Text]  

In Vivo Identification of the Mitogen-Activated Protein Kinase Cascade as a Central Pathogenic Pathway in Experimental Mesangioproliferative Glomerulonephritis

Dirk Bokemeyer, Darius Panek, Herbert J. Kramer, Marion Lindemann, Masashi Kitahara, Peter Boor, Dontscho Kerjaschki, James M. Trzaskos, Jürgen Floege, and Tammo Ostendorf

J Am Soc Nephrol 13: 1473-1480. [Abstract] [Full Text]  

Aminoglycosides Increase Intracellular Calcium Levels and ERK Activity in Proximal Tubular OK Cells Expressing the Extracellular Calcium-Sensing Receptor

Donald T. Ward, Stuart J. McLarnon, and Daniela Riccardi

J Am Soc Nephrol 13: 1481-1489. [Abstract] [Full Text]  

Clonal Chromosomal Defects in the Molecular Pathogenesis of Refractory Hyperparathyroidism of Uremia

Yasuo Imanishi, Hideki Tahara, Nallasivam Palanisamy, Sarah Spitalny, Isidro B. Salusky, William Goodman, Maria Luisa Brandi, Tilman B. Drüeke, Emile Sarfati, Pablo Ureña, R. S. K. Chaganti, and Andrew Arnold

J Am Soc Nephrol 13: 1490-1498. [Abstract] [Full Text]  

Transforming Growth Factor- Induces Renal Epithelial Jagged-1 Expression in Fibrotic Disease

Jeremiah Morrissey, Guangjie Guo, Kazuaki Moridaira, Melanie Fitzgerald, Ruth McCracken, Timothy Tolley, and Saulo Klahr

J Am Soc Nephrol 13: 1499-1508. [Abstract] [Full Text]  

Hemodynamics, Hypertension, and Vascular Regulation:

Blood Pressure, Cardiac, and Renal Responses to Salt and Deoxycorticosterone Acetate in Mice: Role of Renin Genes

Qing Wang, Edith Hummler, Jürg Nussberger, Sophie Clément, Giulio Gabbiani, Hans R. Brunner, and Michel Burnier

J Am Soc Nephrol 13: 1509-1516. [Abstract] [Full Text]  

Immunology and Pathology:

Renal Tubular Epithelial Expression of the Costimulatory Molecule B7RP-1 (Inducible Costimulator Ligand)

Patricia Wahl, Roland Schoop, Grozdana Bilic, Jörg Neuweiler, Michel Le Hir, Steven K. Yoshinaga, and Rudolf P. Wüthrich

J Am Soc Nephrol 13: 1517-1526. [Abstract] [Full Text]  

Chronic Graft-versus-Host Autoimmune Disease in Fc Receptor chain-deficient Mice Results in Lipoprotein Glomerulopathy

Yutaka Kanamaru, Atsuhito Nakao, Isao Shirato, Ko Okumura, Hideoki Ogawa, Yasuhiko Tomino, and Chisei Ra

J Am Soc Nephrol 13: 1527-1533. [Abstract] [Full Text]  

MCP-1 Induces Inflammatory Activation of Human Tubular Epithelial Cells: Involvement of the Transcription Factors, Nuclear Factor-B and Activating Protein-1

Christiane Viedt, Ralph Dechend, Jianwei Fei, Gertrud M. Hänsch, Jörg Kreuzer, and Stephan R. Orth

J Am Soc Nephrol 13: 1534-1547. [Abstract] [Full Text]  

Molecular Medicine, Genetics and Development:

Loss of the VEGF₁₆₄ and VEGF₁₈₈ Isoforms Impairs Postnatal Glomerular Angiogenesis and Renal Arteriogenesis in Mice

Virginie Mattot, Lieve Moons, Florea Lupu, Daniel Chernavvsky, R. Ariel Gómez, Désiré Collen, and Peter Carmeliet

J Am Soc Nephrol 13: 1548-1560. [Abstract] [Full Text]  

Two Gene Fragments that Direct Podocyte-Specific Expression in Transgenic Mice

Marcus J. Moeller, Silja K. Sanden, Abdulsalam Soofi, Roger C. Wiggins, and Lawrence B. Holzman

J Am Soc Nephrol 13: 1561-1567. [Abstract] [Full Text]  

Transcription Factor Ets-1 Regulates Gelatinase A Gene Expression in Mesangial Cells

Julia Reisdorff, Abdelaziz En-Nia, Ioannis Stefanidis, Jürgen Floege, David H. Lovett, and Peter R. Mertens

J Am Soc Nephrol 13: 1568-1578. [Abstract] [Full Text]  

Pathophysiology of Renal Disease:

Downregulation of Intestinal Cytochrome P450 in Chronic Renal Failure

Francois A. Leblond, Martin Petrucci, Pierre Dubé, Gilbert Bernier, Alain Bonnardeaux, and Vincent Pichette

J Am Soc Nephrol 13: 1579-1585. [Abstract] [Full Text]  

Nephrin TRAP Mice Lack Slit Diaphragms and Show Fibrotic Glomeruli and Cystic Tubular Lesions

Maija Rantanen, Tuula Palmén, Anu Pätäri, Heikki Ahola, Sanna Lehtonen, Eva Åström, Thomas Floss, Franz Vauti, Wolfgang Wurst, Patrizia Ruiz, Dontscho Kerjaschki, and Harry Holthöfer

J Am Soc Nephrol 13: 1586-1594. [Abstract] [Full Text]  

Angiotensin II Increases Parathyroid Hormone-Related Protein (PTHrP) and the Type 1 PTH/PTHrP Receptor in the Kidney

Oscar Lorenzo, Marta Ruiz-Ortega, Pedro Esbrit, Mönica Rupérez, Arantxa Ortega, Soledad Santos, Julia Blanco, Luis Ortega, and Jesus Egido

J Am Soc Nephrol 13: 1595-1607. [Abstract] [Full Text]  

Mineral Metabolism and Bone Disease:

Treatment with Vitamin D and Calcium Reduces Bone Loss after Renal Transplantation: A Randomized Study

Ruud G. L. de Sévaux, Andries J. Hoitsma, Frans H. M. Corstens, and Jack F. M. Wetzels

J Am Soc Nephrol 13: 1608-1614. [Abstract] [Full Text]  

Clinical Nephrology:

Oral Sulodexide Reduces Albuminuria in Microalbuminuric and Macroalbuminuric Type 1 and Type 2 Diabetic Patients: The Di.N.A.S. Randomized Trial

Giovanni Gambaro, Ida Kinalska, Adrian Oksa, Peter Pont’uch, Miluse Hertlová, Jindrich Olsovsky, Jacek Manitius, Domenico Fedele, Stanislaw Czekalski, Jindriska Perusicová, Jan Skrha, Jan Taton, Wladyslaw Grzeszczak, and Gaetano Crepaldi

J Am Soc Nephrol 13: 1615-1625. [Abstract] [Full Text]  

Dialysis:

Association of the Insulin Resistance Syndrome and Microalbuminuria among Nondiabetic Native Americans.The Inter-Tribal Heart Project

Christine M. Hoehner, Kurt J. Greenlund, Stephen Rith-Najarian, Michele L. Casper, and William M. McClellan

J Am Soc Nephrol 13: 1626-1634. [Abstract] [Full Text]  

Epidemiology and Outcomes:

Cumulative Risk for Developing End-Stage Renal Disease in the US Population

Bryce A. Kiberd and Catherine M. Clase

J Am Soc Nephrol 13: 1635-1644. [Abstract] [Full Text]  

Transplantation:

Creatinine Reduction Ratio and 24-Hour Creatinine Excretion on Posttransplant Day Two: Simple and Objective Tools to Define Graft Function

Mahendra V. Govani, Osun Kwon, Thomas D. Batiuk, Martin L. Milgrom, and Ronald S. Filo

J Am Soc Nephrol 13: 1645-1649. [Abstract] [Full Text]  

Identification of Highly Responsive Kidney Transplant Recipients Using Pretransplant Soluble CD30

Caner Süsal, Steffen Pelzl, Bernd Döhler, and Gerhard Opelz

J Am Soc Nephrol 13: 1650-1656. [Abstract] [Full Text]  

BRIEF COMMUNICATIONS:

15-Epi-16-(Para-Fluorophenoxy)-Lipoxin A₄-Methyl Ester, a Synthetic Analogue of 15-epi-Lipoxin A₄, Is Protective in Experimental Ischemic Acute Renal Failure

Martin O. Leonard, Kieran Hannan, Melissa J. Burne, David W. P. Lappin, Peter Doran, Patrick Coleman, Catherine Stenson, Cormac T. Taylor, Frank Daniels, Catherine Godson, Nicos A. Petasis, Hamid Rabb, and Hugh R. Brady

J Am Soc Nephrol 13: 1657-1662. [Abstract] [Full Text]  

DISEASE OF THE MONTH:

Smoking and the Kidney

Stephan R. Orth

J Am Soc Nephrol 13: 1663-1672. [Full Text]  

REVIEWS:

Immunomodulatory Effects of Statins: Mechanisms and Potential Impact on Arteriosclerosis

Wulf Palinski and Sotirios Tsimikas

J Am Soc Nephrol 13: 1673-1681. [Abstract] [Full Text]  

EDITORIALS:

A "Molecular Toolbox" for the Nephrologist

Susan E. Quaggin

J Am Soc Nephrol 13: 1682-1685. [Full Text]  

Perception versus Reality of the Burden of Chronic Kidney Disease in the United States

Joseph Coladonato, Preston Klassen, and William F. Owen, Jr

J Am Soc Nephrol 13: 1686-1688. [Full Text]  

ANNOUNCEMENTS:

J Am Soc Nephrol 13: 1689. [Full Text]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.