THIS MONTH'S HIGHLIGHTS:

This Month’s Highlights

J Am Soc Nephrol 14: A15-A16. [Full Text]  

ASN NEWS:

ASN News

J Am Soc Nephrol 14: A39-A40. [Full Text]  

BASIC SCIENCE:

Cell and Transport Physiology:

Albumin Regulates the Na⁺/H⁺ Exchanger 3 in OKP Cells

Jelena Klisic, Jianning Zhang, Vera Nief, Livia Reyes, Orson W. Moe, and Patrice M. Ambühl

J Am Soc Nephrol 14: 3008-3016. [Abstract] [Full Text]  

Short-Term Regulation of Basolateral Organic Anion Uptake in Proximal Tubular Opossum Kidney Cells: Prostaglandin E₂ Acts via Receptor-Mediated Activation of Protein Kinase A

Christoph Sauvant, Hildegard Holzinger, and Michael Gekle

J Am Soc Nephrol 14: 3017-3026. [Abstract] [Full Text]  

Localization and Regulation of the ATP6V0A4 (a4) Vacuolar H⁺-ATPase Subunit Defective in an Inherited Form of Distal Renal Tubular Acidosis

Paul A. Stehberger, Nicole Schulz, Karin E. Finberg, Fiona E. Karet, Gerhard Giebisch, Richard P. Lifton, John P. Geibel, and Carsten A. Wagner

J Am Soc Nephrol 14: 3027-3038. [Abstract] [Full Text]  

Dimeric Architecture of the Human Bumetanide-Sensitive Na-K-Cl Co-transporter

Patrick G.J.F. Starremans, Ferry F.J. Kersten, Lambertus P.W.J. van den Heuvel, Nine V.A.M. Knoers, and René J.M. Bindels

J Am Soc Nephrol 14: 3039-3046. [Abstract] [Full Text]  

Cell Biology:

Hepatocyte Growth Factor Modulates Matrix Metalloproteinases and Plasminogen Activator/Plasmin Proteolytic Pathways in Progressive Renal Interstitial Fibrosis

Rujun Gong, Abdalla Rifai, Evelyn M. Tolbert, Jason N. Centracchio, and Lance D. Dworkin

J Am Soc Nephrol 14: 3047-3060. [Abstract] [Full Text]  

Increased Renal Vascular Endothelial Growth Factor and Angiopoietins by Angiotensin II Infusion Is Mediated by Both AT₁ and AT₂ Receptors

Bishoy Rizkalla, Josephine M. Forbes, Mark E. Cooper, and Zemin Cao

J Am Soc Nephrol 14: 3061-3071. [Abstract] [Full Text]  

Intracellular Mechanisms of Cyclosporin A–Induced Tubular Cell Apoptosis

Pilar Justo, Corina Lorz, Ana Sanz, Jesus Egido, and Alberto Ortiz

J Am Soc Nephrol 14: 3072-3080. [Abstract] [Full Text]  

Genetics and Development:

A Major Gene Locus Links Early Onset Albuminuria with Renal Interstitial Fibrosis in the MWF Rat with Polygenetic Albuminuria

Angela Schulz, Dorothea Standke, Larisa Kovacevic, Martin Mostler, Peter Kossmehl, Monika Stoll, and Reinhold Kreutz

J Am Soc Nephrol 14: 3081-3089. [Abstract] [Full Text]  

Leukemia Inhibitory Factor Is Involved in Tubular Regeneration after Experimental Acute Renal Failure

Jun Yoshino, Toshiaki Monkawa, Mihoko Tsuji, Matsuhiko Hayashi, and Takao Saruta

J Am Soc Nephrol 14: 3090-3101. [Abstract] [Full Text]  

Hemodynamics and Vascular Regulation:

Decreases in Renal Functional Reserve and Proximal Tubular Fluid Output in Conscious Oophorectomized Rats: Normalization with Sex Hormone Substitution

Camilla Birch Nielsen, Allan Flyvbjerg, Jens Meldgaard Bruun, Axel Forman, Lise Wogensen, and Klaus Thomsen

J Am Soc Nephrol 14: 3102-3110. [Abstract] [Full Text]  

Immunology and Pathology:

IFN-Inducible Protein-10 Has a Differential Role in Podocyte during Thy 1.1 Glomerulonephritis

Gi Dong Han, Hiroko Koike, Takeshi Nakatsue, Kenji Suzuki, Hiroyuki Yoneyama, Shosaku Narumi, Naoto Kobayashi, Peter Mundel, Fujio Shimizu, and Hiroshi Kawachi

J Am Soc Nephrol 14: 3111-3126. [Abstract] [Full Text]  

Polymeric IgA1 from Patients with IgA Nephropathy Upregulates Transforming Growth Factor- Synthesis and Signal Transduction in Human Mesangial Cells via the Renin-Angiotensin System

Kar Neng Lai, Sydney C. W. Tang, Jinn-Yuh Guh, Tsai-Der Chuang, Man Fai Lam, Loretta Y. Y. Chan, Anita W. L. Tsang, and Joseph C. K. Leung

J Am Soc Nephrol 14: 3127-3137. [Abstract] [Full Text]  

Pathophysiology of Renal Disease and Progression:

Identification of Renal Progenitor-Like Tubular Cells that Participate in the Regeneration Processes of the Kidney

Akito Maeshima, Shin Yamashita, and Yoshihisa Nojima

J Am Soc Nephrol 14: 3138-3146. [Abstract] [Full Text]  

Importance of Functional EGF Receptors in Recovery from Acute Nephrotoxic Injury

Zoufei Wang, Jian-Kang Chen, Su-wan Wang, Gilbert Moeckel, and Raymond C. Harris

J Am Soc Nephrol 14: 3147-3154. [Abstract] [Full Text]  

Calcium Oxalate Crystal Adherence to Hyaluronan-, Osteopontin-, and CD44-Expressing Injured/Regenerating Tubular Epithelial Cells in Rat Kidneys

Marino Asselman, Anja Verhulst, Marc E. de Broe, and Carl F. Verkoelen

J Am Soc Nephrol 14: 3155-3166. [Abstract] [Full Text]  

Downregulation of Smad Transcriptional Corepressors SnoN and Ski in the Fibrotic Kidney: An Amplification Mechanism for TGF-1 Signaling

Junwei Yang, Xianghong Zhang, Yingjian Li, and Youhua Liu

J Am Soc Nephrol 14: 3167-3177. [Abstract] [Full Text]  

Role of 12-Lipoxygenase in the Stimulation of p38 Mitogen-Activated Protein Kinase and Collagen 5(IV) in Experimental Diabetic Nephropathy and in Glucose-Stimulated Podocytes

Shin-Wook Kang, Rama Natarajan, Asha Shahed, Cynthia C. Nast, Janine LaPage, Peter Mundel, Clifford Kashtan, and Sharon G. Adler

J Am Soc Nephrol 14: 3178-3187. [Abstract] [Full Text]  

Basic Transplantation:

Cyclosporin A Administration during Pregnancy Induces a Permanent Nephron Deficit in Young Rabbits

Anaïs Tendron, Stéphane Decramer, Eve Justrabo, Jean-Bernard Gouyon, Denis Salomon Semama, and Thierry Gilbert

J Am Soc Nephrol 14: 3188-3196. [Abstract] [Full Text]  

Dendritic Cells Pulsed with Polyomavirus BK Antigen Induce Ex Vivo Polyoma BK Virus–Specific Cytotoxic T-Cell Lines in Seropositive Healthy Individuals and Renal Transplant Recipients

Patrizia Comoli, Sabrina Basso, Alberta Azzi, Antonia Moretta, Riccardo De Santis, Francesco Del Galdo, Raffaele De Palma, Umberto Valente, Arcangelo Nocera, Francesco Perfumo, Franco Locatelli, Rita Maccario, and Fabrizio Ginevri

J Am Soc Nephrol 14: 3197-3204. [Abstract] [Full Text]  

Basic Dialysis:

Mice that Lack Endothelial Nitric Oxide Synthase Are Protected against Functional and Structural Modifications Induced by Acute Peritonitis

Jie Ni, Pierre Moulin, Pierre Gianello, Olivier Feron, Jean-Luc Balligand, and Olivier Devuyst

J Am Soc Nephrol 14: 3205-3216. [Abstract] [Full Text]  

CLINICAL SCIENCE:

Disease of the Month:

Management of Glomerular Proteinuria: A Commentary

William A. Wilmer, Brad H. Rovin, Christopher J. Hebert, Sunil V. Rao, Karen Kumor, and Lee A. Hebert

J Am Soc Nephrol 14: 3217-3232. [Abstract] [Full Text]  

Clinical Nephrology:

Association between Renal Insufficiency and Inducible Ischemia in Patients with Coronary Artery Disease: The Heart and Soul Study

Joachim H. Ix, Michael G. Shlipak, Haiying H. Liu, Nelson B. Schiller, and Mary A. Whooley

J Am Soc Nephrol 14: 3233-3238. [Abstract] [Full Text]  

Sympathetic Nerve Activity Is Inappropriately Increased in Chronic Renal Disease

Inge H.H.T. Klein, Gerry Ligtenberg, Jutta Neumann, P. Liam Oey, Hein A. Koomans, and Peter J. Blankestijn

J Am Soc Nephrol 14: 3239-3244. [Abstract] [Full Text]  

Human Genetics:

1-Adrenergic Blockade Augments Pulsatile PTH Secretion in Humans

Claus P. Schmitt, Jennifer Obry, Reinhard Feneberg, Johannes D. Veldhuis, Otto Mehls, Eberhard Ritz, and Franz Schaefer

J Am Soc Nephrol 14: 3245-3250. [Abstract] [Full Text]  

Dialysis:

Effects of High-Flux Hemodialysis on Clinical Outcomes: Results of the HEMO Study

Alfred K. Cheung, Nathan W. Levin, Tom Greene, Lawrence Agodoa, James Bailey, Gerald Beck, William Clark, Andrew S. Levey, John K. Leypoldt, Daniel B. Ornt, Michael V. Rocco, Gerald Schulman, Steve Schwab, Brendan Teehan, and Garabed Eknoyan

J Am Soc Nephrol 14: 3251-3263. [Abstract] [Full Text]  

Best Threshold for Diagnosis of Stenosis or Thrombosis within Six Months of Access Flow Measurement in Arteriovenous Fistulae

Marcello Tonelli, Gian S. Jhangri, David J. Hirsch, Joanne Marryatt, Paula Mossop, Colleen Wile, and Kailash K. Jindal

J Am Soc Nephrol 14: 3264-3269. [Abstract] [Full Text]  

Association of Comorbid Conditions and Mortality in Hemodialysis Patients in Europe, Japan, and the United States: The Dialysis Outcomes and Practice Patterns Study (DOPPS)

David A. Goodkin, Jennifer L. Bragg-Gresham, Karl G. Koenig, Robert A. Wolfe, Takashi Akiba, Vittorio E. Andreucci, Akira Saito, Hugh C. Rayner, Kiyoshi Kurokawa, Friedrich K. Port, Philip J. Held, and Eric W. Young

J Am Soc Nephrol 14: 3270-3277. [Abstract] [Full Text]  

Transplantation:

Differential Expression of Heme Oxygenase-1 and Vascular Endothelial Growth Factor in Cadaveric and Living Donor Kidneys after Ischemia-Reperfusion

Francine B.C. Lemos, Jan N.M. Ijzermans, Pieter E. Zondervan, Annemiek M.A. Peeters, Sandra van den Engel, Wendy M. Mol, Willem Weimar, and Carla C. Baan

J Am Soc Nephrol 14: 3278-3287. [Abstract] [Full Text]  

REVIEWS:

Genetic Features of Mitochondrial Respiratory Chain Disorders

Agnès Rötig and Arnold Munnich

J Am Soc Nephrol 14: 2995-3007. [Abstract] [Full Text]  

EDITORIALS:

Edema in the Nephrotic Syndrome: New Aspect of an Old Enigma

L. Lee Hamm and Vecihi Batuman

J Am Soc Nephrol 14: 3288-3289. [Full Text]  

Searching for Stem/Progenitor Cells in the Adult Mouse Kidney

Fangming Lin and Peter Igarashi

J Am Soc Nephrol 14: 3290-3292. [Full Text]  

ACKNOWLEDGMENT OF MANUSCRIPT CONSULTANTS:

Acknowledgment of Manuscript Consultants

J Am Soc Nephrol 14: 3293-3295. [Full Text]  

ANNOUNCEMENTS:

J Am Soc Nephrol 14: 3296. [Full Text]  

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