THIS MONTH'S HIGHLIGHTS:

This Month’s Highlights

J Am Soc Nephrol 14: A9-A12. [Full Text]  

ASN NEWS:

ASN News

J Am Soc Nephrol 14: A29-A30. [Full Text]  

NIDDK NEWS:

NIDDK News

J Am Soc Nephrol 14: A52-A54. [Full Text]  

ARTICLES:

Cell and Transport Physiology:

N-Glycosylation at Two Sites Critically Alters Thiazide Binding and Activity of the Rat Thiazide-sensitive Na⁺:Cl^- Cotransporter

Robert S. Hoover, Esteban Poch, Adriana Monroy, Norma Vázquez, Toshiyuki Nishio, Gerardo Gamba, and Steven C. Hebert

J Am Soc Nephrol 14: 271-282. [Abstract] [Full Text]  

Silencing of TonEBP/NFAT5 Transcriptional Activator by RNA Interference

Ki Young Na, Seung Kyoon Woo, Sang Do Lee, and H. Moo Kwon

J Am Soc Nephrol 14: 283-288. [Abstract] [Full Text]  

Hormones, Growth Factors, Cell Signaling, Cell Biology and Structure:

Annexin II Is Present on Renal Epithelial Cells and Binds Calcium Oxalate Monohydrate Crystals

Vivek Kumar, Gerard Farell, Sergio Deganello, and John C. Lieske

J Am Soc Nephrol 14: 289-297. [Abstract] [Full Text]  

Hemodynamics, Hypertension and Vascular Regulation:

Fabry Disease in Mice Is Associated With Age-Dependent Susceptibility to Vascular Thrombosis

Daniel T. Eitzman, Peter F. Bodary, Yuechun Shen, Christian G. Khairallah, Susan R. Wild, Akira Abe, Jacqueline Shaffer-Hartman, and James A. Shayman

J Am Soc Nephrol 14: 298-302. [Abstract] [Full Text]  

Pressure Natriuresis in AT₂ Receptor–Deficient Mice with L-NAME Hypertension

Michael Obst, Volkmar Gross, Jürgen Janke, Maren Wellner, Wolfgang Schneider, and Friedrich C. Luft

J Am Soc Nephrol 14: 303-310. [Abstract] [Full Text]  

The Apolipoprotein E Knockout Mouse: A Model Documenting Accelerated Atherogenesis In Uremia

Moriz Buzello, Johannes Törnig, Jörg Faulhaber, Heimo Ehmke, Eberhard Ritz, and Kerstin Amann

J Am Soc Nephrol 14: 311-316. [Abstract] [Full Text]  

Immunology and Pathology:

Bacterial CpG-DNA Aggravates Immune Complex Glomerulonephritis: Role of TLR9-Mediated Expression of Chemokines and Chemokine Receptors

Hans-Joachim Anders, Bernhard Banas, Yvonne Linde, Lars Weller, Clemens D. Cohen, Matthias Kretzler, Stefan Martin, Volker Vielhauer, Detlef Schlöndorff, and Hermann-Josef Gröne

J Am Soc Nephrol 14: 317-326. [Abstract] [Full Text]  

Enhanced Expression of the CD71 Mesangial IgA1 Receptor in Berger Disease and Henoch-Schönlein Nephritis: Association between CD71 Expression and IgA Deposits

Elie Haddad, Ivan C. Moura, Michelle Arcos-Fajardo, Marie-Alice Macher, Veronique Baudouin, Corinne Alberti, Chantal Loirat, Renato C. Monteiro, and Michel Peuchmaur

J Am Soc Nephrol 14: 327-337. [Abstract] [Full Text]  

Blockade of p38 MAPK Ameliorates Acute Inflammatory Renal Injury in Rat Anti-GBM Glomerulonephritis

Cosimo Stambe, Robert C. Atkins, Greg H. Tesch, Ann M. Kapoun, Prudence A. Hill, George F. Schreiner, and David J. Nikolic-Paterson

J Am Soc Nephrol 14: 338-351. [Abstract] [Full Text]  

Molecular Medicine, Genetics and Development:

Alternatively Used Promoters and Distinct Elements Direct Tissue-Specific Expression of Nephrin

Olga Beltcheva, Sirpa Kontusaari, Sergueï Fetissov, Heli Putaala, Pekka Kilpeläinen, Tomas Hökfelt, and Karl Tryggvason

J Am Soc Nephrol 14: 352-358. [Abstract] [Full Text]  

Molecular Cytogenetic Aberrations in Autosomal Dominant Polycystic Kidney Disease Tissue

Jean Gogusev, Ichiro Murakami, Mireille Doussau, Louise Telvi, Alexandre Stojkoski, Philippe Lesavre, and Dominique Droz

J Am Soc Nephrol 14: 359-366. [Abstract] [Full Text]  

Pathophysiology of Renal Disease:

ETA Receptor Blockade Induces Tubular Cell Proliferation and Cyst Growth in Rats with Polycystic Kidney Disease

Berthold Hocher, Philipp Kalk, Torsten Slowinski, Michael Godes, Alexander Mach, Sophia Herzfeld, Doreen Wiesner, Petra Clara Arck, Hans-H. Neumayer, and Benno Nafz

J Am Soc Nephrol 14: 367-376. [Abstract] [Full Text]  

Therapeutic Role of TGF-–Neutralizing Antibody in Mouse Cyclosporin A Nephropathy: Morphologic Improvement Associated with Functional Preservation

Hong Ling, Xuemei Li, Sharda Jha, Wei Wang, Lina Karetskaya, Bruce Pratt, and Steven Ledbetter

J Am Soc Nephrol 14: 377-388. [Abstract] [Full Text]  

Docosahexaenoic Acid Ameliorates Murine Ischemic Acute Renal Failure and Prevents Increases in mRNA Abundance for both TNF- and Inducible Nitric Oxide Synthase

Mariusz L. Kielar, D. Rohan Jeyarajah, X. J. Zhou, and Christopher Y. Lu

J Am Soc Nephrol 14: 389-396. [Abstract] [Full Text]  

Endothelin A Receptor Blockade and Endothelin B Receptor Blockade Improve Hypokalemic Nephropathy by Different Mechanisms

Shin-ichi Suga, Naomi Yasui, Fumiki Yoshihara, Takeshi Horio, Yuhei Kawano, Kenji Kangawa, and Richard J. Johnson

J Am Soc Nephrol 14: 397-406. [Abstract] [Full Text]  

Mineral Metabolism and Bone Disease:

PTH Pulsatility but Not Calcium Sensitivity Is Restored after Total Parathyroidectomy with Heterotopic Autotransplantation

Claus P. Schmitt, Swee Löcken, Otto Mehls, Johannes D. Veldhuis, Thomas Lehnert, Eberhard Ritz, and Franz Schaefer

J Am Soc Nephrol 14: 407-414. [Abstract] [Full Text]  

Clinical Nephrology:

Mortality Differences by Dialysis Modality among Incident ESRD Patients with and without Coronary Artery Disease

Santhi K. Ganesh, Tempie Hulbert-Shearon, Friedrich K. Port, Kim Eagle, and Austin G. Stack

J Am Soc Nephrol 14: 415-424. [Abstract] [Full Text]  

Enalapril and Losartan Reduce Sympathetic Hyperactivity in Patients with Chronic Renal Failure

Inge H.H.T. Klein, Gerry Ligtenberg, P. Liam Oey, Hein A. Koomans, and Peter J. Blankestijn

J Am Soc Nephrol 14: 425-430. [Abstract] [Full Text]  

Prognostic Value of Myocardial Perfusion Studies in Patients with End-Stage Renal Disease Assessed for Kidney or Kidney-Pancreas Transplantation: A Meta-Analysis

Christian G. Rabbat, Darin J. Treleaven, J. David Russell, David Ludwin, and Deborah J. Cook

J Am Soc Nephrol 14: 431-439. [Abstract] [Full Text]  

15-Deoxyspergualin in Patients with Refractory ANCA-Associated Systemic Vasculitis: A Six-Month Open-Label Trial to Evaluate Safety and Efficacy

Rainer Birck, Klaus Warnatz, Hanns M. Lorenz, Mira Choi, Marion Haubitz, Mathias Grünke, Hans H. Peter, Joachim R. Kalden, Ursula Göbel, Johannes M. Drexler, Osamu Hotta, Rainer Nowack, and Fokko J. van der Woude

J Am Soc Nephrol 14: 440-447. [Abstract] [Full Text]  

Serial Estimates of Serum Permeability Activity and Clinical Correlates in Patients with Native Kidney Focal Segmental Glomerulosclerosis

Daniel Cattran, Tuhina Neogi, Ram Sharma, Ellen T. McCarthy, and Virginia J. Savin

J Am Soc Nephrol 14: 448-453. [Abstract] [Full Text]  

Dialysis:

Bioartificial Kidney Ameliorates Gram-Negative Bacteria-Induced Septic Shock in Uremic Animals

William H. Fissell, Liandi Lou, Simin Abrishami, Deborah A. Buffington, and H. David Humes

J Am Soc Nephrol 14: 454-461. [Abstract] [Full Text]  

Epidemiology and Outcomes:

Electrocardiographic Left Ventricular Hypertrophy in Renal Transplant Recipients: Prognostic Value and Impact of Blood Pressure and Anemia

Claudio Rigatto, Robert Foley, John Jeffery, Carol Negrijn, Carrie Tribula, and Patrick Parfrey

J Am Soc Nephrol 14: 462-468. [Abstract] [Full Text]  

Insulin Resistance and Risk of Chronic Kidney Disease in Nondiabetic US Adults

Jing Chen, Paul Muntner, L. Lee Hamm, Vivian Fonseca, Vecihi Batuman, Paul K. Whelton, and Jiang He

J Am Soc Nephrol 14: 469-477. [Abstract] [Full Text]  

Adjustment for Comorbidity in Studies on Health Status in ESRD Patients: Which Comorbidity Index to Use?

Jeannette G. van Manen, Johanna C. Korevaar, Friedo W. Dekker, Elisabeth W. Boeschoten, Patrick M. M. Bossuyt, and Raymond T. Krediet

J Am Soc Nephrol 14: 478-485. [Abstract] [Full Text]  

A Propensity Analysis of Late Versus Early Nephrologist Referral and Mortality on Dialysis

Wolfgang C. Winkelmayer, William F. Owen, Jr., Raisa Levin, and Jerry Avorn

J Am Soc Nephrol 14: 486-492. [Abstract] [Full Text]  

Transplantation:

Donor Tissue Characteristics Influence Cadaver Kidney Transplant Function and Graft Survival but Not Rejection

Sita Gourishankar, Gian S. Jhangri, Sandra M. Cockfield, and Philip F. Halloran

J Am Soc Nephrol 14: 493-499. [Abstract] [Full Text]  

Dialysis, Kidney Transplantation, or Pancreas Transplantation for Patients with Diabetes Mellitus and Renal Failure: A Decision Analysis of Treatment Options

Greg A. Knoll and Graham Nichol

J Am Soc Nephrol 14: 500-515. [Abstract] [Full Text]  

DISEASE OF THE MONTH:

Eye and Kidney: From Clinical Findings to Genetic Explanations

Hassane Izzedine, Bahram Bodaghi, Vincent Launay-Vacher, and Gilbert Deray

J Am Soc Nephrol 14: 516-529. [Full Text]  

REVIEWS:

Glomerular Hyperfiltration and the Salt Paradox in Early Type 1 Diabetes Mellitus: A Tubulo-Centric View

Volker Vallon, Roland C. Blantz, and Scott Thomson

J Am Soc Nephrol 14: 530-537. [Abstract] [Full Text]  

EDITORIALS:

The Thiazide-Sensitive Na-Cl Cotransporter and Human Disease: Reemergence of an Old Player

David H. Ellison

J Am Soc Nephrol 14: 538-540. [Full Text]  

Circulating Permeability Factors in the Nephrotic Syndrome: A Fresh Look at an Old Problem

Richard J. Glassock

J Am Soc Nephrol 14: 541-543. [Full Text]  

ANNOUNCEMENTS:

J Am Soc Nephrol 14: 544. [Full Text]  

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