THIS MONTH'S HIGHLIGHTS:

This Month’s Highlights

J Am Soc Nephrol 14: A9-A11. [Full Text]  

ASN NEWS:

ASN NEWS

J Am Soc Nephrol 14: A29-A30. [Full Text]  

ARTICLES:

Cell and Transport Physiology:

Na Transport in Autosomal Recessive Polycystic Kidney Disease (ARPKD) Cyst Lining Epithelial Cells

Rajeev Rohatgi, Andrew Greenberg, Christopher R. Burrow, Patricia D. Wilson, and Lisa M. Satlin

J Am Soc Nephrol 14: 827-836. [Abstract] [Full Text]  

Basolateral LAT-2 Has a Major Role in the Transepithelial Flux of L-Cystine in the Renal Proximal Tubule Cell Line OK

Esperanza Fernández, David Torrents, Josep Chillarón, Rafael Martín del Río, Antonio Zorzano, and Manuel Palacín

J Am Soc Nephrol 14: 837-847. [Abstract] [Full Text]  

Hormones, Growth Factors, Cell Signaling, Cell Biology and Structure:

Ras Antagonist Farnesylthiosalicylic Acid (FTS) Reduces Glomerular Cellular Proliferation and Macrophage Number in Rat Thy-1 Nephritis

Helen C. Clarke, Hemant M. Kocher, Arif Khwaja, Yoel Kloog, H. Terence Cook, and Bruce M. Hendry

J Am Soc Nephrol 14: 848-854. [Abstract] [Full Text]  

Activation of Pro-Apoptotic Cascade by Dopamine in Renal Epithelial Cells is Fully Dependent on Hydrogen Peroxide Generation by Monoamine Oxidases

Pascale Bianchi, Marie-Hélène Séguélas, Angelo Parini, and Claudie Cambon

J Am Soc Nephrol 14: 855-862. [Abstract] [Full Text]  

N-Acetyl-Seryl-Aspartyl-Lysyl-Proline Inhibits TGF-–Mediated Plasminogen Activator Inhibitor-1 Expression via Inhibition of Smad Pathway in Human Mesangial Cells

Keizo Kanasaki, Daisuke Koya, Toshiro Sugimoto, Motohide Isono, Atsunori Kashiwagi, and Masakazu Haneda

J Am Soc Nephrol 14: 863-872. [Abstract] [Full Text]  

Mechanism of Increased Angiotensin II Levels in Glomerular Mesangial Cells Cultured in High Glucose

Rekha Singh, Ashok K. Singh, Nahid Alavi, and David J. Leehey

J Am Soc Nephrol 14: 873-880. [Abstract] [Full Text]  

Hemodynamics, Hypertension and Vascular Regulation:

Left Ventricular Remodeling and Renal Function in Never-Treated Essential Hypertension

Pierre Fesler, Guilhem du Cailar, Jean Ribstein, and Albert Mimran

J Am Soc Nephrol 14: 881-887. [Abstract] [Full Text]  

Immunology and Pathology:

Interferon- Augments Acute Macrophage-Mediated Renal Injury Via a Glucocorticoid-Sensitive Mechanism

Yohei Ikezumi, Robert C. Atkins, and David J. Nikolic-Paterson

J Am Soc Nephrol 14: 888-898. [Abstract] [Full Text]  

Renal mRNA Levels as Prognostic Tools in Kidney Diseases

Michael Eikmans, Hans J. Baelde, E. Chris Hagen, Leendert C. Paul, Paul H. C. Eilers, Emile de Heer, and Jan A. Bruijn

J Am Soc Nephrol 14: 899-907. [Abstract] [Full Text]  

Atubular Glomeruli and Glomerulotubular Junction Abnormalities in Diabetic Nephropathy

Behzad Najafian, Youngki Kim, John T. Crosson, and Michael Mauer

J Am Soc Nephrol 14: 908-917. [Abstract] [Full Text]  

Molecular Medicine, Genetics and Development:

Homodimerization and Heterodimerization of the Glomerular Podocyte Proteins Nephrin and NEPH1

Peter Gerke, Tobias B. Huber, Lorenz Sellin, Thomas Benzing, and Gerd Walz

J Am Soc Nephrol 14: 918-926. [Abstract] [Full Text]  

Podocyte Expression of Hypoxia-Inducible Factor (HIF)–1 and HIF–2 during Glomerular Development

Paul B. Freeburg, Barry Robert, Patricia L. St. John, and Dale R. Abrahamson

J Am Soc Nephrol 14: 927-938. [Abstract] [Full Text]  

Control of Oxalate Formation from L-Hydroxyproline in Liver Mitochondria

Tatsuya Takayama, Kimio Fujita, Kazuo Suzuki, Michiko Sakaguchi, Michio Fujie, Erina Nagai, Shinya Watanabe, Arata Ichiyama, and Yoshihide Ogawa

J Am Soc Nephrol 14: 939-946. [Abstract] [Full Text]  

Gene Delivery in Renal Tubular Epithelial Cells Using Recombinant Adeno-Associated Viral Vectors

Sifeng Chen, Anupam Agarwal, Olena Y. Glushakova, Marda S. Jorgensen, Shashikumar K. Salgar, Amy Poirier, Terence R. Flotte, Byron P. Croker, Kirsten M. Madsen, Mark A. Atkinson, William W. Hauswirth, Kenneth I. Berns, and C. Craig Tisher

J Am Soc Nephrol 14: 947-958. [Abstract] [Full Text]  

Pathophysiology of Renal Disease:

Beneficial Effects of Calcimimetics on Progression of Renal Failure and Cardiovascular Risk Factors

Hiroaki Ogata, Eberhard Ritz, Giulio Odoni, Kerstin Amann, and Stephan R. Orth

J Am Soc Nephrol 14: 959-967. [Abstract] [Full Text]  

Amelioration of Diabetic Nephropathy in SPARC-Null Mice

Sekiko Taneda, Jeffrey W. Pippin, E. Helene Sage, Kelly L. Hudkins, Yasuo Takeuchi, William G. Couser, and Charles E. Alpers

J Am Soc Nephrol 14: 968-980. [Abstract] [Full Text]  

Retinoids Regulate the Repairing Process of the Podocytes in Puromycin Aminonucleoside-induced Nephrotic Rats

Akira Suzuki, Takahito Ito, Enyu Imai, Masaya Yamato, Hirotsugu Iwatani, Hiroshi Kawachi, and Masatsugu Hori

J Am Soc Nephrol 14: 981-991. [Abstract] [Full Text]  

Clinical Nephrology:

Additive Effect of ACE Inhibition and Angiotensin II Receptor Blockade in Type I Diabetic Patients with Diabetic Nephropathy

Peter Jacobsen, Steen Andersen, Berit R. Jensen, and Hans-Henrik Parving

J Am Soc Nephrol 14: 992-999. [Abstract] [Full Text]  

Dialysis:

Creatinine Production, Nutrition, and Glomerular Filtration Rate Estimation

Srinivasan Beddhu, Matthew H. Samore, Mark S. Roberts, Gregory J. Stoddard, Lisa M. Pappas, and Alfred K. Cheung

J Am Soc Nephrol 14: 1000-1005. [Abstract] [Full Text]  

Sustained-Release Diltiazem Reduces Myocardial Ischemic Episodes in End-Stage Renal Disease: A Double-Blind, Randomized, Crossover, Placebo-Controlled Trial

Gennaro Cice, Attilio Di Benedetto, Antonello D’Andrea, Salvatore D’Isa, Luigi Ferrara, Pina Elvira Russo, Aldo Iacono, and Raffaele Calabrò

J Am Soc Nephrol 14: 1006-1011. [Abstract] [Full Text]  

Epidemiology and Outcomes:

Octogenarians Reaching End-Stage Renal Disease: Cohort Study of Decision-Making and Clinical Outcomes

Dominique Joly, Dany Anglicheau, Corinne Alberti, Anh-Thu Nguyen, Malik Touam, Jean-Pierre Grünfeld, and Paul Jungers

J Am Soc Nephrol 14: 1012-1021. [Abstract] [Full Text]  

Acute Renal Failure in Patients with Sepsis in a Surgical ICU: Predictive Factors, Incidence, Comorbidity, and Outcome

Eric A.J. Hoste, Norbert H. Lameire, Raymond C. Vanholder, Dominique D. Benoit, Johan M.A. Decruyenaere, and Francis A. Colardyn

J Am Soc Nephrol 14: 1022-1030. [Abstract] [Full Text]  

Transplantation:

Dual Kidneys from Marginal Adult Donors as a Source For Cadaveric Renal Transplantation in the United States

Suphamai Bunnapradist, H. Albin Gritsch, Alice Peng, Stanley C. Jordan, and Yong W. Cho

J Am Soc Nephrol 14: 1031-1036. [Abstract] [Full Text]  

Delayed Graft Function and Cast Nephropathy Associated with Tacrolimus Plus Rapamycin Use

Kelly D. Smith, Lucile E. Wrenshall, Roberto F. Nicosia, Raimund Pichler, Christopher L. Marsh, Charles E. Alpers, Nayak Polissar, and Connie L. Davis

J Am Soc Nephrol 14: 1037-1045. [Abstract] [Full Text]  

The Impact of Repeated Subclinical Acute Rejection on the Progression of Chronic Allograft Nephropathy

Seiichirou Shishido, Hiroshi Asanuma, Hideo Nakai, Yoshiaki Mori, Hiroyuki Satoh, Isamu Kamimaki, Hiroshi Hataya, Masahiro Ikeda, Masataka Honda, and Akira Hasegawa

J Am Soc Nephrol 14: 1046-1052. [Abstract] [Full Text]  

A Novel Mechanism for the Immunomodulatory Functions of Class II MHC–Derived Peptides

Barbara Murphy, Joyce Yu, Qingsheng Jiao, Marvin Lin, Tanuja Chitnis, and Mohamed H. Sayegh

J Am Soc Nephrol 14: 1053-1065. [Abstract] [Full Text]  

BRIEF COMMUNICATIONS:

Gene Therapy Expressing Amino-Terminal Truncated Monocyte Chemoattractant Protein-1 Prevents Renal Ischemia-Reperfusion Injury

Kengo Furuichi, Takashi Wada, Yasunori Iwata, Kiyoki Kitagawa, Ken-ichi Kobayashi, Hiroyuki Hashimoto, Yoshiro Ishiwata, Naohisa Tomosugi, Naofumi Mukaida, Kouji Matsushima, Kensuke Egashira, and Hitoshi Yokoyama

J Am Soc Nephrol 14: 1066-1071. [Abstract] [Full Text]  

DISEASE OF THE MONTH:

Advances in the Pathogenesis, Diagnosis, and Treatment of Thrombotic Thrombocytopenic Purpura

Han-Mou Tsai

J Am Soc Nephrol 14: 1072-1081. [Abstract] [Full Text]  

REVIEWS:

Molecular Mechanisms of Primary Hypercalciuria

Kevin K. Frick and David A. Bushinsky

J Am Soc Nephrol 14: 1082-1095. [Full Text]  

EDITORIALS:

Windows on Renal Biopsy Interpretation: Does mRNA Analysis Represent a New Gold Standard?

Liliane J. Striker and Gary E. Striker

J Am Soc Nephrol 14: 1096-1098. [Full Text]  

Geriatric Nephrology is Coming of Age

Dimitrios G. Oreopoulos and Nada Dimkovic

J Am Soc Nephrol 14: 1099-1101. [Full Text]  

Gene Therapy for Renal Diseases: Its Potential and Limitation

Enyu Imai

J Am Soc Nephrol 14: 1102-1104. [Full Text]  

ANNOUNCEMENTS:

J Am Soc Nephrol 14: 1105. [Full Text]  

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