THIS MONTH'S HIGHLIGHTS:

This Month’s Highlights

J Am Soc Nephrol 15: A14-A16. [Full Text]  

BASIC SCIENCE:

Cell and Transport Physiology:

Investigations of Pharmacologic Properties of the Renal CLC-K1 Chloride Channel Co-expressed with Barttin by the Use of 2-(p-Chlorophenoxy)Propionic Acid Derivatives and Other Structurally Unrelated Chloride Channels Blockers

Antonella Liantonio, Michael Pusch, Alessandra Picollo, Patrizia Guida, Annamaria De Luca, Sabata Pierno, Giuseppe Fracchiolla, Fulvio Loiodice, Paolo Tortorella, and Diana Conte Camerino

J Am Soc Nephrol 15: 13-20. [Abstract] [Full Text]  

Cell Biology:

Oncostatin M, a Cytokine Released by Activated Mononuclear Cells, Induces Epithelial Cell-Myofibroblast Transdifferentiation via Jak/Stat Pathway Activation

Joanna Nightingale, Sharmila Patel, Naotaka Suzuki, Roger Buxton, Ken-ichro Takagi, Jun Suzuki, Yoshihiko Sumi, Atsushi Imaizumi, Roger M. Mason, and Zhi Zhang

J Am Soc Nephrol 15: 21-32. [Abstract] [Full Text]  

Angiotensin II Type 1–Receptor Mediated Changes in Heparan Sulfate Proteoglycans in Human SV40 Transformed Podocytes

Paul-Thomas Brinkkoetter, Simone Holtgrefe, Fokko J. van der Woude, and Benito A. Yard

J Am Soc Nephrol 15: 33-40. [Abstract] [Full Text]  

The Death Domain of Kidney Ankyrin Interacts with Fas and Promotes Fas-Mediated Cell Death in Renal Epithelia

Marcela Del Rio, Abubakr Imam, Maryely DeLeon, Gary Gomez, Jaya Mishra, Qing Ma, Samir Parikh, and Prasad Devarajan

J Am Soc Nephrol 15: 41-51. [Abstract] [Full Text]  

Hemodynamics and Vascular Regulation:

Oxidant Stress Leads to Impaired Regulation of Renal Cortical Oxygen Consumption by Nitric Oxide in the Aging Kidney

Stephen Adler, Harer Huang, Michael S. Wolin, and Pawel M. Kaminski

J Am Soc Nephrol 15: 52-60. [Abstract] [Full Text]  

Immunology and Pathology:

Podocytes Populate Cellular Crescents in a Murine Model of Inflammatory Glomerulonephritis

Marcus J. Moeller, Abdulsalaam Soofi, Inge Hartmann, Michel Le Hir, Roger Wiggins, Wilhelm Kriz, and Lawrence B. Holzman

J Am Soc Nephrol 15: 61-67. [Abstract] [Full Text]  

Heparanase Is Involved in the Pathogenesis of Proteinuria as a Result of Glomerulonephritis

Vicki Levidiotis, Craig Freeman, Chris Tikellis, Mark E. Cooper, and David A. Power

J Am Soc Nephrol 15: 68-78. [Abstract] [Full Text]  

Downregulation of Bcl-2 by Podocytes Is Associated with Progressive Glomerular Injury and Clinical Indices of Poor Renal Prognosis in Human IgA Nephropathy

Lian-Qun Qiu, Raja Sinniah, and Stephen I-Hong Hsu

J Am Soc Nephrol 15: 79-90. [Abstract] [Full Text]  

Pathophysiology of Renal Disease and Progression:

Activin A Is a Potent Activator of Renal Interstitial Fibroblasts

Shin Yamashita, Akito Maeshima, Itaru Kojima, and Yoshihisa Nojima

J Am Soc Nephrol 15: 91-101. [Abstract] [Full Text]  

A₁ Adenosine Receptor Activation Inhibits Inflammation, Necrosis, and Apoptosis after Renal Ischemia-Reperfusion Injury in Mice

H. Thomas Lee, George Gallos, Samih H. Nasr, and Charles W. Emala

J Am Soc Nephrol 15: 102-111. [Abstract] [Full Text]  

Prevention of Acute Ischemic Renal Failure by Targeted Delivery of Growth Factors to the Proximal Tubule in Transgenic Mice: The Efficacy of Parathyroid Hormone-Related Protein and Hepatocyte Growth Factor

Nathalie M. Fiaschi-Taesch, Soledad Santos, Vasumathi Reddy, Scott K. Van Why, William F. Philbrick, Arantxa Ortega, Pedro Esbrit, John J. Orloff, and Adolfo Garcia-Ocaña

J Am Soc Nephrol 15: 112-125. [Abstract] [Full Text]  

Basic Dialysis:

Glycosaminoglycans Enhance the Trifluoroethanol-Induced Extension of ₂-Microglobulin–Related Amyloid Fibrils at a Neutral pH

Suguru Yamamoto, Itaru Yamaguchi, Kazuhiro Hasegawa, Shinobu Tsutsumi, Yuji Goto, Fumitake Gejyo, and Hironobu Naiki

J Am Soc Nephrol 15: 126-133. [Abstract] [Full Text]  

CLINICAL SCIENCE:

Disease of the Month:

Transplant Renal Artery Stenosis

Simona Bruno, Giuseppe Remuzzi, and Piero Ruggenenti

J Am Soc Nephrol 15: 134-141. [Abstract] [Full Text]  

Clinical Nephrology:

Timing of Complications in Percutaneous Renal Biopsy

William L. Whittier and Stephen M. Korbet

J Am Soc Nephrol 15: 142-147. [Abstract] [Full Text]  

Effects of Early and Late Intervention with Epoetin on Left Ventricular Mass among Patients with Chronic Kidney Disease (Stage 3 or 4): Results of a Randomized Clinical Trial

Simon D. Roger, Lawrence P. McMahon, Anthony Clarkson, Alex Disney, David Harris, Carmel Hawley, Helen Healy, Peter Kerr, Kelvin Lynn, Alan Parnham, Roess Pascoe, David Voss, Robert Walker, and Adeera Levin

J Am Soc Nephrol 15: 148-156. [Abstract] [Full Text]  

Corticosteroid Effectiveness in IgA Nephropathy: Long-Term Results of a Randomized, Controlled Trial

Claudio Pozzi, Simeone Andrulli, Lucia Del Vecchio, Patrizia Melis, Giovanni B. Fogazzi, Paolo Altieri, Claudio Ponticelli, and Francesco Locatelli

J Am Soc Nephrol 15: 157-163. [Abstract] [Full Text]  

Human Genetics:

Clinical and Molecular Analysis of Patients with Renal Hypouricemia in Japan-Influence of URAT1 Gene on Urinary Urate Excretion

Kimiyoshi Ichida, Makoto Hosoyamada, Ichiro Hisatome, Atsushi Enomoto, Miho Hikita, Hitoshi Endou, and Tatsuo Hosoya

J Am Soc Nephrol 15: 164-173. [Abstract] [Full Text]  

Epidemiology and Outcomes:

Hemoglobin Levels and Erythropoietin Doses in Hemodialysis and Peritoneal Dialysis Patients in the United States

Jon J. Snyder, Robert N. Foley, David T. Gilbertson, Edward F. Vonesh, and Allan J. Collins

J Am Soc Nephrol 15: 174-179. [Abstract] [Full Text]  

Absence of Association between Organic Solvent Exposure and Risk of Chronic Renal Failure: A Nationwide Population-Based Case-Control Study

C. Michael Fored, Gun Nise, Elisabeth Ejerblad, Jon P. Fryzek, Per Lindblad, Joseph K. McLaughlin, Carl-Gustaf Elinder, and Olof Nyrén

J Am Soc Nephrol 15: 180-186. [Abstract] [Full Text]  

Blood Pressure and the Survival of Renal Allografts from Living Donors

Kevin C. Mange, Harold I. Feldman, Marshall M. Joffe, Kosunarty Fa, and Roy D. Bloom

J Am Soc Nephrol 15: 187-193. [Abstract] [Full Text]  

Dialysis:

Factors that Affect Postdialysis Rebound in Serum Urea Concentration, Including the Rate of Dialysis: Results from the HEMO Study

John T. Daugirdas, Tom Greene, Thomas A. Depner, John Leypoldt, Frank Gotch, Gerald Schulman, and Robert Star

J Am Soc Nephrol 15: 194-203. [Abstract] [Full Text]  

Cardiovascular Comorbidity and Late Referral Impact Arteriovenous Fistula Survival: A Prospective Multicenter Study

Pietro Ravani, Giuliano Brunori, Salvatore Mandolfo, Giovanni Cancarini, Enrico Imbasciati, Daniele Marcelli, and Fabio Malberti

J Am Soc Nephrol 15: 204-209. [Abstract] [Full Text]  

Frequency of Patient–Physician Contact and Patient Outcomes in Hemodialysis Care

Laura C. Plantinga, Nancy E. Fink, John H. Sadler, Andrew S. Levey, Nathan W. Levin, Haya R. Rubin, Josef Coresh, Michael J. Klag, and Neil R. Powe

J Am Soc Nephrol 15: 210-218. [Abstract] [Full Text]  

Transplantation:

Proteomic-Based Detection of Urine Proteins Associated with Acute Renal Allograft Rejection

Stefan Schaub, David Rush, John Wilkins, Ian W. Gibson, Tracey Weiler, Kevin Sangster, Lindsay Nicolle, Martin Karpinski, John Jeffery, and Peter Nickerson

J Am Soc Nephrol 15: 219-227. [Abstract] [Full Text]  

Addition of Sirolimus to Cyclosporine Delays the Recovery from Delayed Graft Function but Does not Affect 1-Year Graft Function

Giovanni Stallone, Salvatore Di Paolo, Antonio Schena, Barbara Infante, Michele Battaglia, Pasquale Ditonno, Loreto Gesualdo, Giuseppe Grandaliano, and Francesco Paolo Schena

J Am Soc Nephrol 15: 228-233. [Abstract] [Full Text]  

REVIEWS:

Epithelial to Mesenchymal Transition in Renal Fibrogenesis: Pathologic Significance, Molecular Mechanism, and Therapeutic Intervention

Youhua Liu

J Am Soc Nephrol 15: 1-12. [Abstract] [Full Text]  

SPECIAL COMMENTARY:

Diets For Patients With Chronic Kidney Disease, Still Worth Prescribing

William E. Mitch and Guiseppe Remuzzi

J Am Soc Nephrol 15: 234-237. [Full Text]  

EDITORIALS:

Frequency of Physician Visits to Patients on In-Center Maintenance Hemodialysis: Does One Strategy Fit All?

Thomas A. Golper

J Am Soc Nephrol 15: 238-239. [Full Text]  

ANNOUNCEMENTS:

J Am Soc Nephrol 15: 240. [Full Text]  

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