THIS MONTH'S HIGHLIGHTS:

This Month’s Highlights

J Am Soc Nephrol 15: 2955-2958 [Full Text] [PDF]  

REVIEWS:

Vascular Calcification Mechanisms

Cecilia M. Giachelli

J Am Soc Nephrol 15: 2959-2964 [Abstract] [Full Text] [PDF]  

Organ Transplantation: Halfway through the First Century

Alden M. Doyle, Robert I. Lechler, and Laurence A. Turka

J Am Soc Nephrol 15: 2965-2971 [Full Text] [PDF]  

BASIC SCIENCE:

Cell and Transport Physiology:

Calcineurin A Is Central to the Expression of the Renal Type II Na/Pi Co-transporter Gene and to the Regulation of Renal Phosphate Transport

Yulia Moz, Ronen Levi, Vardit Lavi-Moshayoff, Keith B. Cox, Jeffery D. Molkentin, Justin Silver, and Tally Naveh-Many

J Am Soc Nephrol 15: 2972-2980 [Abstract] [Full Text] [PDF]  

Human Podocytes Possess a Stretch-Sensitive, Ca²⁺-Activated K⁺ Channel: Potential Implications for the Control of Glomerular Filtration

Michael J. Morton, Katie Hutchinson, Peter W. Mathieson, Ian R. Witherden, Moin A. Saleem, and Malcolm Hunter

J Am Soc Nephrol 15: 2981-2987 [Abstract] [Full Text] [PDF]  

Regulation of the Cl^–/HCO₃^– Exchanger AE2 in Rat Thick Ascending Limb of Henle’s Loop in Response to Changes in Acid-Base and Sodium Balance

Fabienne Quentin, Dominique Eladari, Sebastian Frische, Michèle Cambillau, Søren Nielsen, Seth L. Alper, Michel Paillard, and Régine Chambrey

J Am Soc Nephrol 15: 2988-2997 [Abstract] [Full Text] [PDF]  

Indomethacin Enhances Shuttling of Aquaporin-2 Despite Decreased Abundance in Rat Kidney

Soo Wan Kim, Joon Wan Kim, Ki Chul Choi, Seong Kwon Ma, YoonWha Oh, Ju-Young Jung, Jin Kim, and JongUn Lee

J Am Soc Nephrol 15: 2998-3005 [Abstract] [Full Text] [PDF]  

Cell Biology:

Src-Family Kinase Fyn Phosphorylates the Cytoplasmic Domain of Nephrin and Modulates Its Interaction with Podocin

Hongping Li, Serge Lemay, Lamine Aoudjit, Hiroshi Kawachi, and Tomoko Takano

J Am Soc Nephrol 15: 3006-3015 [Abstract] [Full Text] [PDF]  

Role of Parathyroid Hormone–Related Protein in the Regulation of Stretch-Induced Renal Vascular Smooth Muscle Cell Proliferation

Eric Schordan, Sandra Welsch, Sylvie Rothhut, Alain Lambert, Mariette Barthelmebs, Jean-Jacques Helwig, and Thierry Massfelder

J Am Soc Nephrol 15: 3016-3025 [Abstract] [Full Text] [PDF]  

Oxidized LDL Induces Proliferation and Hypertrophy in Human Umbilical Vein Endothelial Cells via Regulation of p27^Kip1 Expression: Role of RhoA

Stefan Seibold, Dorothea Schürle, Alexandra Heinloth, Gunter Wolf, Martin Wagner, and Jan Galle

J Am Soc Nephrol 15: 3026-3034 [Abstract] [Full Text] [PDF]  

Genetics and Development:

A Functional Floxed Allele of Pkd1 that Can Be Conditionally Inactivated In Vivo

Klaus B. Piontek, David L. Huso, Alexander Grinberg, Lijuan Liu, Djahida Bedja, Haidan Zhao, Kathleen Gabrielson, Feng Qian, Changlin Mei, Heiner Westphal, and Gregory G. Germino

J Am Soc Nephrol 15: 3035-3043 [Abstract] [Full Text] [PDF] [Supplementary Figure for "A Functional Floxed Allele of Pkd1 ...]  

The Major Podocyte Protein Nephrin Is Transcriptionally Activated by the Wilms’ Tumor Suppressor WT1

Nicole Wagner, Kay-Dietrich Wagner, Yiming Xing, Holger Scholz, and Andreas Schedl

J Am Soc Nephrol 15: 3044-3051 [Abstract] [Full Text] [PDF]  

Mineral Metabolism and Bone Disease:

Modulation of Proliferating Renal Epithelial Cell Affinity for Calcium Oxalate Monohydrate Crystals

Gerard Farell, Erick Huang, Soo Y. Kim, Rüdiger Horstkorte, and John C. Lieske

J Am Soc Nephrol 15: 3052-3062 [Abstract] [Full Text] [PDF]  

Pathophysiology of Renal Disease and Progression:

Reversal of Glomerular Lesions Involves Coordinated Restructuring of Glomerular Microvasculature

Marcin Adamczak, Marie-Luise Gross, Kerstin Amann, and Eberhard Ritz

J Am Soc Nephrol 15: 3063-3072 [Abstract] [Full Text] [PDF]  

Amelioration of Ischemic Acute Renal Injury by Neutrophil Gelatinase-Associated Lipocalin

Jaya Mishra, Kiyoshi Mori, Qing Ma, Caitlin Kelly, Jun Yang, Mark Mitsnefes, Jonathan Barasch, and Prasad Devarajan

J Am Soc Nephrol 15: 3073-3082 [Abstract] [Full Text] [PDF]  

Expression and Function of Ets-1 during Experimental Acute Renal Failure in Rats

Hiroyuki Tanaka, Yoshio Terada, Takahiko Kobayashi, Tomokazu Okado, Seiji Inoshita, Michio Kuwahara, Arun Seth, Yasufumi Sato, and Sei Sasaki

J Am Soc Nephrol 15: 3083-3092 [Abstract] [Full Text] [PDF]  

Acute Renal Failure in Endotoxemia is Dependent on Caspase Activation

Rongqing Guo, Ying Wang, Andrew W. Minto, Richard J. Quigg, and Patrick N. Cunningham

J Am Soc Nephrol 15: 3093-3102 [Abstract] [Full Text] [PDF]  

Myocardial Infarction Enhances Progressive Renal Damage in an Experimental Model for Cardio-Renal Interaction

Richard P.E. van Dokkum, Wouter B.A. Eijkelkamp, Alex C.A. Kluppel, Rob H. Henning, Harry van Goor, Marin Citgez, Willemijn A.K.M. Windt, Dirk J. van Veldhuisen, Pieter A. de Graeff, and Dick de Zeeuw

J Am Soc Nephrol 15: 3103-3110 [Abstract] [Full Text] [PDF]  

Basic Dialysis:

Acute Peritoneal Dialysis in Rats Results in a Marked Reduction of Interstitial Colloid Osmotic Pressure

Bert-Inge Rosengren, Bengt Rippe, Olav Tenstad, and Helge Wiig

J Am Soc Nephrol 15: 3111-3116 [Abstract] [Full Text] [PDF]  

CLINICAL SCIENCE:

Clinical Nephrology:

Continuum of Renoprotection with Losartan at All Stages of Type 2 Diabetic Nephropathy: A Post Hoc Analysis of the RENAAL Trial Results

Giuseppe Remuzzi, Piero Ruggenenti, Annalisa Perna, Borislav D. Dimitrov, Dick de Zeeuw, Darcy A. Hille, Shahnaz Shahinfar, George W. Carides, Barry M. Brenner for the RENAAL Study Group

J Am Soc Nephrol 15: 3117-3125 [Abstract] [Full Text] [PDF]  

Pharmacologic Demonstration of the Synergistic Effects of a Combination of the Renin Inhibitor Aliskiren and the AT1 Receptor Antagonist Valsartan on the Angiotensin II–Renin Feedback Interruption

Michel Azizi, Joël Ménard, Alvine Bissery, Than-Tam Guyenne, Alessandra Bura-Rivière, Sujata Vaidyanathan, and Riccardo P. Camisasca

J Am Soc Nephrol 15: 3126-3133 [Abstract] [Full Text] [PDF]  

Epidemiology and Outcomes:

Resting Energy Expenditure and Subsequent Mortality Risk in Peritoneal Dialysis Patients

Angela Yee-Moon Wang, Mandy Man-Mei Sea, Nelson Tang, John E. Sanderson, Siu-Fai Lui, Philip Kam-Tao Li, and Jean Woo

J Am Soc Nephrol 15: 3134-3143 [Abstract] [Full Text] [PDF]  

Frequency of Sit-Down Patient Care Rounds, Attainment of Clinical Performance Targets, Hospitalization, and Mortality in Hemodialysis Patients

Laura C. Plantinga, Nancy E. Fink, Bernard G. Jaar, John H. Sadler, Josef Coresh, Michael J. Klag, Andrew S. Levey, and Neil R. Powe

J Am Soc Nephrol 15: 3144-3153 [Abstract] [Full Text] [PDF]  

Hemoglobin Targets for the Anemia of Chronic Kidney Disease: A Meta-analysis of Randomized, Controlled Trials

Giovanni F.M. Strippoli, Jonathan C. Craig, Carlo Manno, and Francesco P. Schena

J Am Soc Nephrol 15: 3154-3165 [Abstract] [Full Text] [PDF]  

Impact of Diabetes and Hepatitis after Kidney Transplantation on Patients Who Are Affected by Hepatitis C Virus

Kevin C. Abbott, Krista L. Lentine, Jay R. Bucci, Lawrence Y. Agodoa, Jonathan M. Koff, Kent C. Holtzmuller, and Mark A. Schnitzler

J Am Soc Nephrol 15: 3166-3174 [Abstract] [Full Text] [PDF]  

A Comparison of Iothalamate-GFR and Serum Creatinine-Based Outcomes: Acceleration in the Rate of GFR Decline in the African American Study of Kidney Disease and Hypertension

Julia Lewis, Tom Greene, Lawrence Appel, Gabriel Contreras, Janice Douglas, Jim Lash, Robert Toto, Fredrick Van Lente, Xuelei Wang, Jackson T. Wright, Jr. for the AASK Study Group

J Am Soc Nephrol 15: 3175-3183 [Abstract] [Full Text] [PDF]  

Inflammatory and Prothrombotic Markers and the Progression of Renal Disease in Elderly Individuals

Linda Fried, Cam Solomon, Michael Shlipak, Stephen Seliger, Catherine Stehman-Breen, Anthony J. Bleyer, Paolo Chaves, Curt Furberg, Lewis Kuller, and Anne Newman

J Am Soc Nephrol 15: 3184-3191 [Abstract] [Full Text] [PDF]  

Clinical Dialysis:

Safety and Efficacy of Low Molecular Weight Heparins for Hemodialysis in Patients with End-Stage Renal Failure: A Meta-analysis of Randomized Trials

Wendy Lim, Deborah J. Cook, and Mark A. Crowther

J Am Soc Nephrol 15: 3192-3206 [Abstract] [Full Text] [PDF]  

Short Bacterial DNA Fragments: Detection in Dialysate and Induction of Cytokines

Ralf Schindler, Werner Beck, Reinhold Deppisch, Mario Aussieker, Adelheid Wilde, Hermann Göhl, and Ulrich Frei

J Am Soc Nephrol 15: 3207-3214 [Abstract] [Full Text] [PDF]  

The Critical Role of Src Homology Domain 2–Containing Tyrosine Phosphatase-1 in Recombinant Human Erythropoietin Hyporesponsive Anemia in Chronic Hemodialysis Patients

Shigeru Akagi, Haruo Ichikawa, Tatsuo Okada, Ai Sarai, Taro Sugimoto, Hisanori Morimoto, Takashi Kihara, Ai Yano, Kazushi Nakao, Yoshio Nagake, Jun Wada, and Hirofumi Makino

J Am Soc Nephrol 15: 3215-3224 [Abstract] [Full Text] [PDF]  

Human Mineral Metabolism and Bone Disease:

Dietary Factors and the Risk of Incident Kidney Stones in Men: New Insights after 14 Years of Follow-up

Eric N. Taylor, Meir J. Stampfer, and Gary C. Curhan

J Am Soc Nephrol 15: 3225-3232 [Abstract] [Full Text] [PDF]  

Clinical Transplantation:

Insulin Resistance after Renal Transplantation: The Effect of Steroid Dose Reduction and Withdrawal

Karsten Midtvedt, Jøran Hjelmesæth, Anders Hartmann, Kirsten Lund, Dag Paulsen, Thore Egeland, and Trond Jenssen

J Am Soc Nephrol 15: 3233-3239 [Abstract] [Full Text] [PDF]  

Bioinformatic Analysis of the Urine Proteome of Acute Allograft Rejection

Edmond O’Riordan, Tatyana N. Orlova, Jianfeng Mei J, Khalid Butt, Praveen M. Chander, Shafiq Rahman, Muong Mya, Rena Hu, Jahangir Momin, Elizabeth W. Eng, Dierk J. Hampel, Bertram Hartman, Matthias Kretzler, Veronica Delaney, and Michael S. Goligorsky

J Am Soc Nephrol 15: 3240-3248 [Abstract] [Full Text] [PDF]  

Hepatitis C, Acute Humoral Rejection, and Renal Allograft Survival

John P. Forman, Nina Tolkoff-Rubin, Manuel Pascual, and Julie Lin

J Am Soc Nephrol 15: 3249-3255 [Abstract] [Full Text] [PDF]  

Evaluation of Intravenous Immunoglobulin as an Agent to Lower Allosensitization and Improve Transplantation in Highly Sensitized Adult Patients with End-Stage Renal Disease: Report of the NIH IG02 Trial

Stanley C. Jordan, Dolly Tyan, Don Stablein, Matthew McIntosh, Steve Rose, Ashley Vo, Mieko Toyoda, Connie Davis, Ron Shapiro, Deborah Adey, Dawn Milliner, Ralph Graff, Robert Steiner, Gaetano Ciancio, Shobah Sahney, and Jimmy Light

J Am Soc Nephrol 15: 3256-3262 [Abstract] [Full Text] [PDF]  

EDITORIALS:

Renal Transplantation: A Half Century of Success and the Long Road Ahead

Bruce Kaplan and Herwig-Ulf Meier-Kriesche

J Am Soc Nephrol 15: 3270-3271 [Full Text] [PDF]  

Farewell to Lippincott Williams & Wilkins: JASN Moves to Self-Publication

William G. Couser and Bonnie O’Brien

J Am Soc Nephrol 15: 3272 [Full Text] [PDF]  

SPECIAL FEATURE:

Payment for Quality in End-Stage Renal Disease

Jonathan Himmelfarb, Brian J.G. Pereira, Donald E. Wesson, Paul C. Smedberg, and William L. Henrich

J Am Soc Nephrol 15: 3263-3269 [Full Text] [PDF]  

ACKNOWLEDGMENT OF MANUSCRIPT CONSULTANTS:

ACKNOWLEDGMENT OF MANUSCRIPT CONSULTANTS

William G. Couser Editor-in-Chief

J Am Soc Nephrol 15: 3273-3276 [Full Text] [PDF]  

ANNOUNCEMENTS:

ANNOUNCEMENTS

J Am Soc Nephrol 15: 3277 [Full Text] [PDF]  

ERRATA:

Correction

J Am Soc Nephrol 15: A9 [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.