THIS MONTH'S HIGHLIGHTS:

This Month’s Highlights

J Am Soc Nephrol 15: A26-A29. [Full Text]  

ASN NEWS:

ASN News

J Am Soc Nephrol 15: A39-A40. [Full Text]  

BASIC SCIENCE:

Cell and Transport Physiology:

Function and Localization of Urate Transporter 1 in Mouse Kidney

Makoto Hosoyamada, Kimiyoshi Ichida, Atsushi Enomoto, Tatsuo Hosoya, and Hitoshi Endou

J Am Soc Nephrol 15: 261-268. [Abstract] [Full Text]  

Acute and Chronic Regulation of Thick Ascending Limb Endothelial Nitric Oxide Synthase by Statins

Marisela Varela and Jeffrey L. Garvin

J Am Soc Nephrol 15: 269-275. [Abstract] [Full Text]  

Cell Biology:

Activation of the Signal Transducer and Activator of Transcription Signaling Pathway in Renal Proximal Tubular Cells by Albumin

Hideaki Nakajima, Masaru Takenaka, Jun-Ya Kaimori, Takayuki Hamano, Hirotsugu Iwatani, Takeshi Sugaya, Takahito Ito, Masatsugu Hori, and Enyu Imai

J Am Soc Nephrol 15: 276-285. [Abstract] [Full Text]  

Exogenous PDGF-D Is a Potent Mesangial Cell Mitogen and Causes a Severe Mesangial Proliferative Glomerulopathy

Kelly L. Hudkins, Debra G. Gilbertson, Matthew Carling, Sekiko Taneda, Steven D. Hughes, Matthew S. Holdren, Thomas E. Palmer, Stavros Topouzis, Aaron C. Haran, Andrew L. Feldhaus, and Charles E. Alpers

J Am Soc Nephrol 15: 286-298. [Abstract] [Full Text]  

Genetics and Development:

Rescue of Defective Branching Nephrogenesis in Renal-Coloboma Syndrome by the Caspase Inhibitor, Z-VAD-fmk

Patsy Clark, Alison Dziarmaga, Michael Eccles, and Paul Goodyer

J Am Soc Nephrol 15: 299-305. [Abstract] [Full Text]  

Hemodynamics and Vascular Regulation:

The SOD Mimetic Tempol Ameliorates Glomerular Injury and Reduces Mitogen-Activated Protein Kinase Activity in Dahl Salt-Sensitive Rats

Akira Nishiyama, Masanori Yoshizumi, Hirofumi Hitomi, Shoji Kagami, Shuji Kondo, Akira Miyatake, Megumu Fukunaga, Toshiaki Tamaki, Hideyasu Kiyomoto, Masakazu Kohno, Takatomi Shokoji, Shoji Kimura, and Youichi Abe

J Am Soc Nephrol 15: 306-315. [Abstract] [Full Text]  

₂-Adrenoceptor Activation Attenuates Endotoxin-Induced Acute Renal Failure

Akio Nakamura, Akira Imaizumi, Yukishige Yanagawa, Takao Kohsaka, and Edward J. Johns

J Am Soc Nephrol 15: 316-325. [Abstract] [Full Text]  

Immunology and Pathology:

p38 Mitogen-Activated Protein Kinase Activation and Cell Localization in Human Glomerulonephritis: Correlation with Renal Injury

Cosimo Stambe, David J. Nikolic-Paterson, Prudence A. Hill, John Dowling, and Robert C. Atkins

J Am Soc Nephrol 15: 326-336. [Abstract] [Full Text]  

Chemokine Receptor CCR1 But Not CCR5 Mediates Leukocyte Recruitment and Subsequent Renal Fibrosis after Unilateral Ureteral Obstruction

Vaclav Eis, Bruno Luckow, Volker Vielhauer, Jens T. Siveke, Yvonne Linde, Stephan Segerer, Guillermo Perez de Lema, Clemens D. Cohen, Matthias Kretzler, Matthias Mack, Richard Horuk, Philip M. Murphy, Ji-Liang Gao, Kelly L. Hudkins, Charles E. Alpers, Hermann-Josef Gröne, Detlef Schlöndorff, and Hans-Joachim Anders

J Am Soc Nephrol 15: 337-347. [Abstract] [Full Text]  

Pathophysiology of Renal Disease and Progression:

Beneficial Effects of Estrogens on Indices of Renal Damage in Uninephrectomized SHRsp Rats

Marie-Luise Gross, Marcin Adamczak, Thomas Rabe, Nevin Ali Harbi, Jan Krtil, Andreas Koch, Peter Hamar, Kerstin Amann, and Eberhard Ritz

J Am Soc Nephrol 15: 348-358. [Abstract] [Full Text]  

Successful Treatment of an Adynamic Bone Disorder with Bone Morphogenetic Protein-7 in a Renal Ablation Model

Richard J. Lund, Matthew R. Davies, Alex J. Brown, and Keith A. Hruska

J Am Soc Nephrol 15: 359-369. [Abstract] [Full Text]  

The Role of p38 Mitogen-Activated Protein Kinase Activation in Renal Fibrosis

Cosimo Stambe, Robert C. Atkins, Greg H. Tesch, Takao Masaki, George F. Schreiner, and David J. Nikolic-Paterson

J Am Soc Nephrol 15: 370-379. [Abstract] [Full Text]  

Paracetamol-Induced Renal Tubular Injury: A Role for ER Stress

Corina Lorz, Pilar Justo, Ana Sanz, Dolores Subirá, Jesús Egido, and Alberto Ortiz

J Am Soc Nephrol 15: 380-389. [Abstract] [Full Text]  

Basic Transplantation:

Chronic Renal Allograft Dysfunction: The Role of T Cell–Mediated Tubular Epithelial to Mesenchymal Cell Transition

Helen Robertson, Simi Ali, Benjamin J. McDonnell, Alastair D. Burt, and John A. Kirby

J Am Soc Nephrol 15: 390-397. [Abstract] [Full Text]  

CLINICAL SCIENCE:

Disease of the Month:

Anti-Erythropoietin Antibodies and Pure Red Cell Aplasia

Jerome Rossert, Nicole Casadevall, and Kai-Uwe Eckardt

J Am Soc Nephrol 15: 398-406. [Full Text]  

Clinical Nephrology:

The Value of N-Acetylcysteine in the Prevention of Radiocontrast Agent-Induced Nephropathy Seems Questionable

Ute Hoffmann, Michael Fischereder, Bernd Krüger, Wolfgang Drobnik, and Bernhard K. Krämer

J Am Soc Nephrol 15: 407-410. [Abstract] [Full Text]  

Epidemiology and Outcomes:

The Number, Quality, and Coverage of Randomized Controlled Trials in Nephrology

Giovanni F. M. Strippoli, Jonathan C. Craig, and Francesco P. Schena

J Am Soc Nephrol 15: 411-419. [Abstract] [Full Text]  

Randomized Trial of Folic Acid for Prevention of Cardiovascular Events in End-Stage Renal Disease

Elizabeth M. Wrone, John M. Hornberger, James L. Zehnder, Linda M. McCann, Norman S. Coplon, and Stephen P. Fortmann

J Am Soc Nephrol 15: 420-426. [Abstract] [Full Text]  

Postoperative Mortality after Nontraumatic Lower Extremity Amputation in Patients with Renal Insufficiency

Ann M. O’Hare, Joe Feinglass, Gayle E. Reiber, Rudolph A. Rodriguez, Jennifer Daley, Shukri Khuri, William G. Henderson, and Kirsten L. Johansen

J Am Soc Nephrol 15: 427-434. [Abstract] [Full Text]  

Analysis of the Relationship between Norepinephrine and Asymmetric Dimethyl Arginine Levels among Patients with End-Stage Renal Disease

Francesca Mallamaci, Giovanni Tripepi, Renke Maas, Lorenzo Malatino, Rainer Böger, and Carmine Zoccali

J Am Soc Nephrol 15: 435-441. [Abstract] [Full Text]  

A Low, Rather than a High, Total Plasma Homocysteine Is an Indicator of Poor Outcome in Hemodialysis Patients

Kamyar Kalantar-Zadeh, Gladys Block, Michael H. Humphreys, Charles J. McAllister, and Joel D. Kopple

J Am Soc Nephrol 15: 442-453. [Abstract] [Full Text]  

Effect of Nosocomial Bloodstream Infection on the Outcome of Critically Ill Patients with Acute Renal Failure Treated with Renal Replacement Therapy

Eric A. J. Hoste, Stijn I. Blot, Norbert H. Lameire, Raymond C. Vanholder, Dirk De Bacquer, and Francis A. Colardyn

J Am Soc Nephrol 15: 454-462. [Abstract] [Full Text]  

Dialysis:

The Relationship Between Systemic and Whole-Body Hematocrit Is Not Constant during Ultrafiltration on Hemodialysis

Sandip Mitra, Paul Chamney, Roger Greenwood, and Ken Farrington

J Am Soc Nephrol 15: 463-469. [Abstract] [Full Text]  

Increased Plasma S-Nitrosothiol Concentrations Predict Cardiovascular Outcomes among Patients with End-Stage Renal Disease: A Prospective Study

Ziad A. Massy, Christine Fumeron, Didier Borderie, Philippe Tuppin, Thao Nguyen-Khoa, Marie-Odile Benoit, Christian Jacquot, Claude Buisson, Tilman B. Drüeke, Ohvanesse G. Ekindjian, Bernard Lacour, and Marie-Christine Iliou

J Am Soc Nephrol 15: 470-476. [Abstract] [Full Text]  

Vascular Access and All-Cause Mortality: A Propensity Score Analysis

Kevan R. Polkinghorne, Stephen P. McDonald, Robert C. Atkins, and Peter G. Kerr

J Am Soc Nephrol 15: 477-486. [Abstract] [Full Text]  

A Randomized, Controlled Trial of Albumin versus Saline for the Treatment of Intradialytic Hypotension

Greg A. Knoll, Jenny A. Grabowski, Geoffrey F. Dervin, and Keith O’Rourke

J Am Soc Nephrol 15: 487-492. [Abstract] [Full Text]  

Human Renal Pathology:

Chymase-like Angiotensin II–Generating Activity in End-Stage Human Autosomal Dominant Polycystic Kidney Disease

Elizabeth A. McPherson, Zaiming Luo, Rachel A. Brown, Linda S. LeBard, Christopher C. Corless, Robert C. Speth, and Susan P. Bagby

J Am Soc Nephrol 15: 493-500. [Abstract] [Full Text]  

SPECIAL FEATURE:

The Classification of Glomerulonephritis in Systemic Lupus Erythematosus Revisited

Jan J. Weening, Vivette D. D’Agati, Melvin M. Schwartz, Surya V. Seshan, Charles E. Alpers, Gerald B. Appel, James E. Balow, Jan A. Bruijn, Terence Cook, Franco Ferrario, Agnes B. Fogo, Ellen M. Ginzler, Lee Hebert, Gary Hill, Prue Hill, J. Charles Jennette, Norella C. Kong, Philippe Lesavre, Michael Lockshin, Lai-Meng Looi, Hirofumi Makino, Luiz A. Moura, and Michio Nagata

J Am Soc Nephrol 15: 241-250. [Abstract] [Full Text]  

REVIEWS:

N-Acetylcysteine In The Prevention Of Radiocontrast-Induced Nephropathy

Steven Fishbane, John H. Durham, Kevin Marzo, and Michael Rudnick

J Am Soc Nephrol 15: 251-260. [Abstract] [Full Text]  

EDITORIALS:

Reclassification of Lupus Glomerulonephritis: Back to the Future

Richard J. Glassock

J Am Soc Nephrol 15: 501-503. [Full Text]  

Albumin Signals the Coming of Age of Proteinuric Nephropathy

Nigel J. Brunskill

J Am Soc Nephrol 15: 504-505. [Full Text]  

Clinical Trial in Nephrology at Hard End Point?

Dick de Zeeuw and Pieter A. de Graeff

J Am Soc Nephrol 15: 506-508. [Full Text]  

ERRATA:

Correction

J Am Soc Nephrol 15: 509-510. [Full Text]  

ANNOUNCEMENTS:

ANNOUNCEMENTS

J Am Soc Nephrol 15: 511. [Full Text]  

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