THIS MONTH'S HIGHLIGHTS:

This Month's Highlights

J Am Soc Nephrol 15: 1367-1369 [Full Text]  

REVIEWS:

Renal Epithelial Traffic Jams and One-Way Streets

Mark A.J. Devonald and Fiona E. Karet

J Am Soc Nephrol 15: 1370-1381 [Full Text]  

Signaling at the Slit Diaphragm

Thomas Benzing

J Am Soc Nephrol 15: 1382-1391 [Full Text]  

BASIC SCIENCE:

Cell and Transport Physiology:

Phosphate-Induced Vascular Calcification: Role of Pyrophosphate and Osteopontin

Koba A. Lomashvili, Scott Cobbs, Randolph A. Hennigar, Kenneth I. Hardcastle, and W. Charles O’Neill

J Am Soc Nephrol 15: 1392-1401 [Abstract] [Full Text]  

Cell Biology:

Hepatocyte Growth Factor Antagonizes the Profibrotic Action of TGF-1 in Mesangial Cells by Stabilizing Smad Transcriptional Corepressor TGIF

Chunsun Dai and Youhua Liu

J Am Soc Nephrol 15: 1402-1412 [Abstract] [Full Text]  

Role of Nitric Oxide in the Renal Hemodynamic Response to Unilateral Nephrectomy

David H. Sigmon, Edgard Gonzalez-Feldman, Maria A. Cavasin, D’Anna L. Potter, and William H. Beierwaltes

J Am Soc Nephrol 15: 1413-1420 [Abstract] [Full Text]  

Differential Expression of Calcineurin A Isoforms in the Diabetic Kidney

Jennifer L. Gooch, Pablo E. Pèrgola, Rebecca L. Guler, Hanna E. Abboud, and Jeffrey L. Barnes

J Am Soc Nephrol 15: 1421-1429 [Abstract] [Full Text]  

Reduction in Connective Tissue Growth Factor by Antisense Treatment Ameliorates Renal Tubulointerstitial Fibrosis

Hideki Yokoi, Masashi Mukoyama, Tetsuya Nagae, Kiyoshi Mori, Takayoshi Suganami, Kazutomo Sawai, Tetsuro Yoshioka, Masao Koshikawa, Takashi Nishida, Masaharu Takigawa, Akira Sugawara, and Kazuwa Nakao

J Am Soc Nephrol 15: 1430-1440 [Abstract] [Full Text]  

Inactivation of Endoplasmic Reticulum Bound Ca²⁺-Independent Phospholipase A₂ in Renal Cells during Oxidative Stress

Brian S. Cummings, Andrew K. Gelasco, Gilbert R. Kinsey, Jane Mchowat, and Rick G. Schnellmann

J Am Soc Nephrol 15: 1441-1451 [Abstract] [Full Text]  

Genetics and Development:

Angiotensin II Increases Pax-2 Expression in Fetal Kidney Cells Via the AT₂ Receptor

Shao-Ling Zhang, Babak Moini, and Julie R. Ingelfinger

J Am Soc Nephrol 15: 1452-1465 [Abstract] [Full Text]  

Mouse Model of X-Linked Alport Syndrome

Michelle N. Rheault, Stefan M. Kren, Beth K. Thielen, Hector A. Mesa, John T. Crosson, William Thomas, Yoshikazu Sado, Clifford E. Kashtan, and Yoav Segal

J Am Soc Nephrol 15: 1466-1474 [Abstract] [Full Text]  

Angiotensin II Type 1 Receptor Overexpression in Podocytes Induces Glomerulosclerosis in Transgenic Rats

Sigrid Hoffmann, Dirk Podlich, Brunhilde Hähnel, Wilhelm Kriz, and Norbert Gretz

J Am Soc Nephrol 15: 1475-1487 [Abstract] [Full Text]  

Hemodynamics and Vascular Regulation:

Anandamide Decreases Glomerular Filtration Rate through Predominant Vasodilation of Efferent Arterioles in Rat Kidneys

Yukako Koura, Atsuhiro Ichihara, Yuko Tada, Yuki Kaneshiro, Hirokazu Okada, Constance J. Temm, Matsuhiko Hayashi, and Takao Saruta

J Am Soc Nephrol 15: 1488-1494 [Abstract] [Full Text]  

Increased Expression of Adhesion Molecules in Uremic Atherosclerosis in Apolipoprotein-E–Deficient Mice

Susanne Bro, Flemming Moeller, Claus B. Andersen, Klaus Olgaard, and Lars B. Nielsen

J Am Soc Nephrol 15: 1495-1503 [Abstract] [Full Text]  

Basic Immunology and Pathology:

Late Onset of Treatment with a Chemokine Receptor CCR1 Antagonist Prevents Progression of Lupus Nephritis in MRL-Fas(lpr) Mice

Hans-Joachim Anders, Emilia Belemezova, Vaclav Eis, Stephan Segerer, Volker Vielhauer, Guillermo Perez de Lema, Matthias Kretzler, Clemens D. Cohen, Michael Frink, Richard Horuk, Kelly L. Hudkins, Charles E. Alpers, Francisco Mampaso, and Detlef Schlöndorff

J Am Soc Nephrol 15: 1504-1513 [Abstract] [Full Text]  

Pathophysiology of Renal Disease and Progression:

Angiotensin II, via AT₁ and AT₂ Receptors and NF-B Pathway, Regulates the Inflammatory Response in Unilateral Ureteral Obstruction

Vanesa Esteban, Oscar Lorenzo, Mónica Rupérez, Yusuke Suzuki, Sergio Mezzano, Julia Blanco, Mathias Kretzler, Takeshi Sugaya, Jesús Egido, and Marta Ruiz-Ortega

J Am Soc Nephrol 15: 1514-1529 [Abstract] [Full Text]  

Increased Infarct Size in Uremic Rats: Reduced Ischemia Tolerance?

Ralf Dikow, Lars Philipp Kihm, Martin Zeier, Jolanthe Kapitza, Johannes Törnig, Kerstin Amann, Christiane Tiefenbacher, and Eberhard Ritz

J Am Soc Nephrol 15: 1530-1536 [Abstract] [Full Text]  

Regulation of Muscle Protein Degradation: Coordinated Control of Apoptotic and Ubiquitin-Proteasome Systems by Phosphatidylinositol 3 Kinase

Seoung Woo Lee, Guoli Dai, Zhaoyong Hu, Xiaonan Wang, Jie Du, and William E. Mitch

J Am Soc Nephrol 15: 1537-1545 [Abstract] [Full Text]  

Glomerulosclerosis and Tubulointerstitial Fibrosis are Attenuated with 17-Estradiol in the Aging Dahl Salt Sensitive Rat

Christine Maric, Kathryn Sandberg, and Carmen Hinojosa-Laborde

J Am Soc Nephrol 15: 1546-1556 [Abstract] [Full Text]  

Differential Inhibition of HSP72 and HSP25 Produces Profound Impairment of Cellular Integrity

Michael Riordan, Vivek Garg, Gunilla Thulin, Michael Kashgarian, and Norman J. Siegel

J Am Soc Nephrol 15: 1557-1566 [Abstract] [Full Text]  

Dependence of Oxalate Absorption on the Daily Calcium Intake

Gerd E. von Unruh, Susanne Voss, Tilman Sauerbruch, and Albrecht Hesse

J Am Soc Nephrol 15: 1567-1573 [Abstract] [Full Text]  

Hypoperfusion of Peritubular Capillaries Induces Chronic Hypoxia before Progression of Tubulointerstitial Injury in a Progressive Model of Rat Glomerulonephritis

Makiko Matsumoto, Tetsuhiro Tanaka, Tokunori Yamamoto, Eisei Noiri, Toshio Miyata, Reiko Inagi, Toshiro Fujita, and Masaomi Nangaku

J Am Soc Nephrol 15: 1574-1581 [Abstract] [Full Text]  

CLINICAL SCIENCE:

Disease of the Month:

Malignancy in Renal Transplantation

Christian Morath, Martina Mueller, Hartmut Goldschmidt, Vedat Schwenger, Gerhard Opelz, and Martin Zeier

J Am Soc Nephrol 15: 1582-1588 [Full Text]  

Clinical Nephrology:

Acute Metabolic Acidosis: Characterization and Diagnosis of the Disorder and the Plasma Potassium Response

Jean-Martin Wiederseiner, Juergen Muser, Thomas Lutz, Henry N. Hulter, and Reto Krapf

J Am Soc Nephrol 15: 1589-1596 [Abstract] [Full Text]  

Minimal Changes of Serum Creatinine Predict Prognosis in Patients after Cardiothoracic Surgery: A Prospective Cohort Study

Andrea Lassnigg, Daniel Schmidlin, Mohamed Mouhieddine, Lucas M. Bachmann, Wilfred Druml, Peter Bauer, and Michael Hiesmayr

J Am Soc Nephrol 15: 1597-1605 [Abstract] [Full Text]  

Kidney Protein Dynamics and Ammoniagenesis in Humans with Chronic Metabolic Acidosis

Giacomo Garibotto, Antonella Sofia, Cristina Robaudo, Stefano Saffioti, Maria Rita Sala, Daniela Verzola, Monica Vettore, Rodolfo Russo, Vanessa Procopio, Giacomo Deferrari, and Paolo Tessari

J Am Soc Nephrol 15: 1606-1615 [Abstract] [Full Text]  

Development Of Chronic Kidney Disease and Cardiovascular Prognosis in Essential Hypertensive Patients

Julián Segura, Carlos Campo, Paloma Gil, Cecilia Roldán, Luis Vigil, José L. Rodicio, and Luis M. Ruilope

J Am Soc Nephrol 15: 1616-1622 [Abstract] [Full Text]  

Epidemiology and Outcomes:

Administration of Parenteral Iron and Mortality among Hemodialysis Patients

Harold I. Feldman, Marshall Joffe, Bruce Robinson, Jill Knauss, Borut Cizman, Wensheng Guo, Eunice Franklin-Becker, and Gerald Faich

J Am Soc Nephrol 15: 1623-1632 [Abstract] [Full Text]  

Human Immunodeficiency Virus Infection and Kidney Transplantation in the Era of Highly Active Antiretroviral Therapy and Modern Immunosuppression

Kevin C. Abbott, S. John Swanson, Lawrence Y.C. Agodoa, and Paul L. Kimmel

J Am Soc Nephrol 15: 1633-1639 [Abstract] [Full Text]  

Development, Prevention, and Potential Reversal of Left Ventricular Hypertrophy in Chronic Kidney Disease

Lawrence P. McMahon, Simon D. Roger, and Adeera Levin

J Am Soc Nephrol 15: 1640-1647 [Abstract] [Full Text]  

Clinical Dialysis:

Non–Transferrin-Bound Iron in the Serum of Hemodialysis Patients Who Receive Ferric Saccharate: No Correlation to Peroxide Generation

Barbara Scheiber-Mojdehkar, Barbara Lutzky, Roland Schaufler, Brigitte Sturm, and Hans Goldenberg

J Am Soc Nephrol 15: 1648-1655 [Abstract] [Full Text]  

Clinical Transplantation:

Incorporating Recipient Choice in Kidney Transplantation

Xuanming Su, Stefanos A. Zenios, and Glenn M. Chertow

J Am Soc Nephrol 15: 1656-1663 [Abstract] [Full Text]  

EDITORIALS:

Pathophysiology Underlying Accelerated Atherogenesis in Renal Disease: Closing in on the Target

Kerstin Amann, Marie-Luise Gross, and Eberhard Ritz

J Am Soc Nephrol 15: 1664-1666 [Full Text]  

PCO₂ and [K⁺]_p in Metabolic Acidosis: Certainty for the First and Uncertainty for the Other

Horacio J. Adrogué and Nicolaos E. Madias

J Am Soc Nephrol 15: 1667-1668 [Full Text]  

ANNOUNCEMENTS:

ASN NEWS

J Am Soc Nephrol 15: A25-A27 [Full Text]  

Announcements

J Am Soc Nephrol 15: 1669 [Full Text]  

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