THIS MONTH'S HIGHLIGHTS:

This Month’s Highlights

J Am Soc Nephrol 15: 1967-1970 [Full Text]  

FRONTIERS IN NEPHROLOGY:

Mechanisms of Hypertension: Cells, Hormones, and the Kidney:

Overview: Mechanisms of Hypertension: Cells, Hormones, and the Kidney

Phyllis August

J Am Soc Nephrol 15: 1971-1973 [Full Text]  

Ischemic Nephropathy: Where Are We Now?

Stephen C. Textor

J Am Soc Nephrol 15: 1974-1982 [Abstract] [Full Text]  

Endothelial Dysfunction

Dierk H. Endemann and Ernesto L. Schiffrin

J Am Soc Nephrol 15: 1983-1992 [Abstract] [Full Text]  

Mechanisms of Hypertension: The Expanding Role of Aldosterone

E. Marie Freel and John M.C. Connell

J Am Soc Nephrol 15: 1993-2001 [Abstract] [Full Text]  

BASIC SCIENCE:

Cell and Transport Physiology:

Differential Regulation of Basolateral Cl^–/HCO₃^– Exchangers SLC26A7 and AE1 in Kidney Outer Medullary Collecting Duct

Sharon Barone, Hassane Amlal, Jie Xu, Minna Kujala, Juha Kere, Snezana Petrovic, and Manoocher Soleimani

J Am Soc Nephrol 15: 2002-2011 [Abstract] [Full Text]  

The Renal-Specific Transporter Mediates Facilitative Transport of Organic Anions at the Brush Border Membrane of Mouse Renal Tubules

Tomoki Imaoka, Hiroyuki Kusuhara, Satomi Adachi-Akahane, Maki Hasegawa, Naomi Morita, Hitoshi Endou, and Yuichi Sugiyama

J Am Soc Nephrol 15: 2012-2022 [Abstract] [Full Text]  

Homocysteine and the Renal Epithelial Transport and Toxicity of Inorganic Mercury: Role of Basolateral Transporter Organic Anion Transporter 1

Rudolfs K. Zalups and Sarfaraz Ahmad

J Am Soc Nephrol 15: 2023-2031 [Abstract] [Full Text]  

Cell Biology:

High Ambient Glucose Enhances Sensitivity to TGF-1 via Extracellular Signal—Regulated Kinase and Protein Kinase C Activities in Human Mesangial Cells

Tomoko Hayashida and H. William Schnaper

J Am Soc Nephrol 15: 2032-2041 [Abstract] [Full Text]  

Genetics and Development:

Siah-1 Interacts with the Intracellular Region of Polycystin-1 and Affects Its Stability via the Ubiquitin-Proteasome Pathway

Hyunho Kim, Woocho Jeong, Kwangseog Ahn, Curie Ahn, and Seongman Kang

J Am Soc Nephrol 15: 2042-2049 [Abstract] [Full Text]  

Specific Cre/Lox Recombination in the Mouse Proximal Tubule

Isabelle Rubera, Chantal Poujeol, Guillaume Bertin, Lilia Hasseine, Laurent Counillon, Philippe Poujeol, and Michel Tauc

J Am Soc Nephrol 15: 2050-2056 [Abstract] [Full Text]  

Basic Mineral Metabolism:

An Acidic Peptide Sequence of Nucleolin-Related Protein Can Mediate the Attachment of Calcium Oxalate to Renal Tubule Cells

Elena A. Sorokina, Jeffrey A. Wesson, and Jack G. Kleinman

J Am Soc Nephrol 15: 2057-2065 [Abstract] [Full Text]  

Basic Immunology and Pathology:

Coupled Induction of iNOS and p53 Upregulation in Renal Resident Cells May Be Linked with Apoptotic Activity in the Pathogenesis of Progressive IgA Nephropathy

Lian-Qun Qiu, Raja Sinniah, and Stephen I-Hong Hsu

J Am Soc Nephrol 15: 2066-2078 [Abstract] [Full Text]  

Podocyte Flattening and Disorder of Glomerular Basement Membrane Are Associated with Splitting of Dystroglycan-Matrix Interaction

Kenichiro Kojima, Agnes Davidovits, Helga Poczewski, Brigitte Langer, Shunya Uchida, Katalyn Nagy-Bojarski, Anny Hovorka, Roland Sedivy, and Dontscho Kerjaschki

J Am Soc Nephrol 15: 2079-2089 [Abstract] [Full Text]  

Mitogenic Signaling of Urokinase Receptor–Deficient Kidney Fibroblasts: Actions of an Alternative Urokinase Receptor and LDL Receptor–Related Protein

Guoqiang Zhang, Xiaohe Cai, Jesús M. López-Guisa, Sarah J. Collins, and Allison A. Eddy

J Am Soc Nephrol 15: 2090-2102 [Abstract] [Full Text]  

Circumvention of Normal Constraints on Granule Protein Gene Expression in Peripheral Blood Neutrophils and Monocytes of Patients with Antineutrophil Cytoplasmic Autoantibody–Associated Glomerulonephritis

Jia Jin Yang, William F. Pendergraft, David A. Alcorta, Patrick H. Nachman, Susan L. Hogan, Robin P. Thomas, Pamela Sullivan, J. Charles Jennette, Ronald J. Falk, and Gloria A. Preston

J Am Soc Nephrol 15: 2103-2114 [Abstract] [Full Text]  

Pathophysiology of Renal Disease and Progression:

Erythropoietin Protects the Kidney against the Injury and Dysfunction Caused by Ischemia-Reperfusion

Edward J. Sharples, Nimesh Patel, Paul Brown, Keith Stewart, Helder Mota-Philipe, Michael Sheaff, Julius Kieswich, David Allen, Steven Harwood, Martin Raftery, Christoph Thiemermann, and Muhammad M. Yaqoob

J Am Soc Nephrol 15: 2115-2124 [Abstract] [Full Text] [HTML Page - index.htslp]  

Accelerated Nephropathy in Diabetic Apolipoprotein E-Knockout Mouse: Role of Advanced Glycation End Products

Markus Lassila, Kwee K. Seah, Terri J. Allen, Vicki Thallas, Merlin C. Thomas, Riccardo Candido, Wendy C. Burns, Josephine M. Forbes, Anna C. Calkin, Mark E. Cooper, and Karin A.M. Jandeleit-Dahm

J Am Soc Nephrol 15: 2125-2138 [Abstract] [Full Text]  

Interactions between Angiotensin II and NF-B–Dependent Pathways in Modulating Macrophage Infiltration in Experimental Diabetic Nephropathy

Fiona T.H. Lee, Zemin Cao, David M. Long, Sianna Panagiotopoulos, George Jerums, Mark E. Cooper, and Josephine M. Forbes

J Am Soc Nephrol 15: 2139-2151 [Abstract] [Full Text]  

Involvement of Peripheral Benzodiazepine Receptor in the Oxidative Stress, Death-Signaling Pathways, and Renal Injury Induced by Ischemia-Reperfusion

Oxana R. Kunduzova, Ghislaine Escourrou, France De La Farge, Robert Salvayre, Marie-Hélène Séguélas, Nathalie Leducq, Françoise Bono, Jean-Marc Herbert, and Angelo Parini

J Am Soc Nephrol 15: 2152-2160 [Abstract] [Full Text]  

CLINICAL SCIENCE:

Disease of the Month:

From Finland to Fatland: Beneficial Effects of Statins for Patients with Chronic Kidney Disease

Behdad Afzali, Ali A. Haydar, Katie Vinen, and David J.A. Goldsmith

J Am Soc Nephrol 15: 2161-2168 [Abstract] [Full Text]  

Clinical Nephrology:

Focal Segmental Glomerulosclerosis in Nephrotic Adults: Presentation, Prognosis, and Response to Therapy of the Histologic Variants

Micky J. Chun, Stephen M. Korbet, Melvin M. Schwartz, and Edmund J. Lewis

J Am Soc Nephrol 15: 2169-2177 [Abstract] [Full Text]  

Epidemiology and Outcomes:

Association between Smoking and Chronic Renal Failure in a Nationwide Population-Based Case-Control Study

Elisabeth Ejerblad, C. Michael Fored, Per Lindblad, Jon Fryzek, Paul W. Dickman, Carl-Gustaf Elinder, Joseph K. McLaughlin, and Olof Nyrén

J Am Soc Nephrol 15: 2178-2185 [Abstract] [Full Text]  

Inflammation, Residual Kidney Function, and Cardiac Hypertrophy Are Interrelated and Combine Adversely to Enhance Mortality and Cardiovascular Death Risk of Peritoneal Dialysis Patients

Angela Yee-Moon Wang, Mei Wang, Jean Woo, Christopher Wai-Kei Lam, Siu-Fai Lui, Philip Kam-Tao Li, and John E. Sanderson

J Am Soc Nephrol 15: 2186-2194 [Abstract] [Full Text]  

Renal Function, Digoxin Therapy, and Heart Failure Outcomes: Evidence from the Digoxin Intervention Group Trial

Michael G. Shlipak, Grace L. Smith, Saif S. Rathore, Barry M. Massie, and Harlan M. Krumholz

J Am Soc Nephrol 15: 2195-2203 [Abstract] [Full Text]  

Clinical Dialysis:

Pure Red Cell Aplasia Secondary to Epoetin alpha Responding to Darbepoetin Alpha in a Patient on Peritoneal Dialysis

Ashwin Asari and Ram Gokal

J Am Soc Nephrol 15: 2204-2207 [Abstract] [Full Text]  

Human Mineral Metabolism and Bone Disease:

Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis

Geoffrey A. Block, Preston S. Klassen, J. Michael Lazarus, Norma Ofsthun, Edmund G. Lowrie, and Glenn M. Chertow

J Am Soc Nephrol 15: 2208-2218 [Abstract] [Full Text]  

Does the Phosphate Binder Lanthanum Carbonate Affect Bone in Rats with Chronic Renal Failure?

Geert J. Behets, Geert Dams, Sven R. Vercauteren, Stephen J. Damment, Roger Bouillon, Marc E. De Broe, and Patrick C. D’Haese

J Am Soc Nephrol 15: 2219-2228 [Abstract] [Full Text]  

Clinical Transplantation:

Angiotensin Converting Enzyme Genotype and Chronic Allograft Nephropathy in Protocol Biopsies

Miguel Hueso, Pedro Alía, Francesc Moreso, Violeta Beltrán-Sastre, Luis Riera, Carlota González, Miguel Ángel Navarro, Josep Maria Grinyó, Estanis Navarro, and Daniel Serón

J Am Soc Nephrol 15: 2229-2236 [Abstract] [Full Text]  

EDITORIALS:

Kidney-Specific Gene Targeting

Peter Igarashi

J Am Soc Nephrol 15: 2237-2239 [Full Text]  

Erythropoietin Is More than Just a Promoter of Erythropoiesis

Josef Pfeilschifter and Andrea Huwiler

J Am Soc Nephrol 15: 2240-2241 [Full Text]  

ASN NEWS:

ASN NEWS

J Am Soc Nephrol 15: A36-A37 [Full Text]  

ERRATA:

Correction

J Am Soc Nephrol 15: A8 [Full Text]  

Correction

J Am Soc Nephrol 15: A8 [Full Text]  

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