JASN -- Table of Contents (16 [12])

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THIS MONTH'S HIGHLIGHTS:

This Month’s Highlights: J Am Soc Nephrol 16: 3447-3448. [Full Text] [PDF]

Nephrology beyond JASN:

Heart Failure after Myocardial Infarction—Benefit beyond Hemoglobin from Erythropoietin: Erythropoietin Induces Neovascularization and Improves Cardiac Function in Rats with Heart Failure after Myocardial Infarction: P Van der Meer, E Lipsic, RH Henning, K Boddeus, J van der Velden, AA Voors, DJ van Veldhuisen, WH van Gilst, RG Schoemaker, JC Leemans, G Stokman, N Claessen, KM Rouschop, G Teske, CJ Kirschning, S Akira, T van der Poll, JJ Weening, and S Florquin; J Am Soc Nephrol 16: 3449-3454. [Full Text] [PDF]

Editorials:

Autotopes and Allotopes: Clifford Kashtan; J Am Soc Nephrol 16: 3455-3457. [Full Text] [PDF]

Novel Mechanism of P-Fimbriated Escherichia coli Virulence in Pyelonephritis: Ann Stapleton; J Am Soc Nephrol 16: 3458-3460. [Full Text] [PDF]

Race and Kidney Disease Outcomes: Genes or Environment?: Sylvia Ramirez; J Am Soc Nephrol 16: 3461-3463. [Full Text] [PDF]

Special Features:

The Kidneys in the Bible: What Happened?: Garabed Eknoyan; J Am Soc Nephrol 16: 3464-3471. [Abstract] [Full Text] [PDF]

Glomerular Disease Workshop: Catherine M. Meyers, Mark Geanacopoulos, Lawrence B. Holzman, and David J. Salant; J Am Soc Nephrol 16: 3472-3476. [Abstract] [Full Text] [PDF]

Reviews:

Observational Research Databases in Renal Disease: Michael Shlipak and Catherine Stehman-Breen; J Am Soc Nephrol 16: 3477-3484. [Abstract] [Full Text] [PDF]

Fast Track:

NIMA-Related Kinases Defective in Murine Models of Polycystic Kidney Diseases Localize to Primary Cilia and Centrosomes: Moe R. Mahjoub, Melissa L. Trapp, and Lynne M. Quarmby; J Am Soc Nephrol 16: 3485-3489. [Abstract] [Full Text] [PDF]

Cell and Transport Physiology:

Role of Mitochondrial Na⁺ Concentration, Measured by CoroNa Red, in the Protection of Metabolically Inhibited MDCK Cells: Szilvia Baron, Adrian Caplanusi, Martin van de Ven, Mihai Radu, Sanda Despa, Ivo Lambrichts, Marcel Ameloot, Paul Steels, and Ilse Smets; J Am Soc Nephrol 16: 3490-3497. [Abstract] [Full Text] [PDF]

Modulation of Renal Apical Organic Anion Transporter 4 Function by Two PDZ Domain–Containing Proteins: Hiroki Miyazaki, Naohiko Anzai, Sophapun Ekaratanawong, Takeshi Sakata, Ho Jung Shin, Promsuk Jutabha, Taku Hirata, Xin He, Hiroshi Nonoguchi, Kimio Tomita, Yoshikatsu Kanai, and Hitoshi Endou; J Am Soc Nephrol 16: 3498-3506. [Abstract] [Full Text] [PDF]

Cell Biology:

Extracellular ATP Determines 11 ${beta}$ -Hydroxysteroid Dehydrogenase Type 2 Activity via Purinergic Receptors: Bert Kadereit, Pierre Fustier, Kushiar Shojaati, Brigitte M. Frey, Felix J. Frey, and Markus G. Mohaupt; J Am Soc Nephrol 16: 3507-3516. [Abstract] [Full Text] [PDF]

Genetics and Development:

Missense Mutation in Sterile ${alpha}$ Motif of Novel Protein SamCystin is Associated with Polycystic Kidney Disease in (cy/+) Rat: Joanna H. Brown, Marie-Thérèse Bihoreau, Sigrid Hoffmann, Bettina Kränzlin, Iulia Tychinskaya, Nicholas Obermüller, Dirk Podlich, Suzanne N. Boehn, Pamela J. Kaisaki, Natalia Megel, Patrick Danoy, Richard R. Copley, John Broxholme, Ralph Witzgall, Mark Lathrop, Norbert Gretz, and Dominique Gauguier; J Am Soc Nephrol 16: 3517-3526. [Abstract] [Full Text] [PDF] [Data Supplements]

Nephrogenic Factors Promote Differentiation of Mouse Embryonic Stem Cells into Renal Epithelia: Doyeob Kim and Gregory R. Dressler; J Am Soc Nephrol 16: 3527-3534. [Abstract] [Full Text] [PDF]

Nephron Function in Transgenic Mice with Selective Vascular or Tubular Expression of Angiotensin-Converting Enzyme: Sean P. Kessler, Seiji Hashimoto, Preenie S. Senanayake, Christina Gaughan, Ganes C. Sen, and Jurgen Schnermann; J Am Soc Nephrol 16: 3535-3542. [Abstract] [Full Text] [PDF]

Protein Kinase X Activates Ureteric Bud Branching Morphogenesis in Developing Mouse Metanephric Kidney: Xiaohong Li, Deborah P. Hyink, Katalin Polgar, G. Luca Gusella, Patricia D. Wilson, and Christopher R. Burrow; J Am Soc Nephrol 16: 3543-3552. [Abstract] [Full Text] [PDF]

Hemodynamics and Vascular Regulation:

Uric Acid–Induced C-Reactive Protein Expression: Implication on Cell Proliferation and Nitric Oxide Production of Human Vascular Cells: Duk-Hee Kang, Sung-Kwang Park, In-Kyu Lee, and Richard J. Johnson; J Am Soc Nephrol 16: 3553-3562. [Abstract] [Full Text] [PDF]

Basic Immunology and Pathology:

Distinct Epitopes for Anti–Glomerular Basement Membrane Alport Alloantibodies and Goodpasture Autoantibodies within the Noncollagenous Domain of ${alpha}$ 3(IV) Collagen: A Janus-Faced Antigen: Xu-Ping Wang, Agnes B. Fogo, Selene Colon, Giovanna Giannico, Sameh R. Abul-Ezz, Jeffrey H. Miner, and Dorin-Bogdan Borza; J Am Soc Nephrol 16: 3563-3571. [Abstract] [Full Text] [PDF]

C5a Receptor Deficiency Attenuates T Cell Function and Renal Disease in MRL^lpr Mice: Scott E. Wenderfer, Baozhen Ke, Travis J. Hollmann, Rick A. Wetsel, Hui Yao Lan, and Michael C. Braun; J Am Soc Nephrol 16: 3572-3582. [Abstract] [Full Text] [PDF]

Pyelonephritic Escherichia coli Expressing P Fimbriae Decrease Immune Response of the Mouse Kidney: James C. Rice, Tao Peng, Jeff S. Spence, Hui-Qun Wang, Randall M. Goldblum, Blaise Corthésy, and Bogdan J. Nowicki; J Am Soc Nephrol 16: 3583-3591. [Abstract] [Full Text] [PDF]

Chemokine Receptor Ccr2 Deficiency Reduces Renal Disease and Prolongs Survival in MRL/lpr Lupus-Prone Mice: Guillermo Pérez de Lema, Holger Maier, Tobias J. Franz, Maríia Escribese, Silvia Chilla, Stephan Segerer, Natalia Camarasa, Holger Schmid, Bernhard Banas, Svetoslav Kalaydjiev, Dirk H. Busch, Klaus Pfeffer, Francisco Mampaso, Detlef Schlöndorff, and Bruno Luckow; J Am Soc Nephrol 16: 3592-3601. [Abstract] [Full Text] [PDF]

Basic Mineral Metabolism:

Tissue Kallikrein–Deficient Mice Display a Defect in Renal Tubular Calcium Absorption: Nicolas Picard, Monique Van Abel, Christelle Campone, Michelle Seiler, May Bloch-Faure, Joost G.J. Hoenderop, Johannes Loffing, Pierre Meneton, René J.M. Bindels, Michel Paillard, François Alhenc-Gelas, and Pascal Houillier; J Am Soc Nephrol 16: 3602-3610. [Abstract] [Full Text] [PDF]

Pathophysiology of Renal Disease and Progression:

Activation of G ${alpha}$ q-Coupled Signaling Pathways in Glomerular Podocytes Promotes Renal Injury: Liming Wang, Timothy A. Fields, Kathy Pazmino, Qunsheng Dai, James L. Burchette, David N. Howell, Thomas M. Coffman, and Robert F. Spurney; J Am Soc Nephrol 16: 3611-3622. [Abstract] [Full Text] [PDF]

Renal Structural and Functional Repair in a Mouse Model of Reversal of Ureteral Obstruction: Anita L. Cochrane, Michelle M. Kett, Chrishan S. Samuel, Naomi V. Campanale, Warwick P. Anderson, David A. Hume, Melissa H. Little, John F. Bertram, and Sharon D. Ricardo; J Am Soc Nephrol 16: 3623-3630. [Abstract] [Full Text] [PDF]

Renoprotective Properties of Angiotensin Receptor Blockers beyond Blood Pressure Lowering: Yuko Izuhara, Masaomi Nangaku, Reiko Inagi, Naoto Tominaga, Toru Aizawa, Kiyoshi Kurokawa, Charles van Ypersele de Strihou, and Toshio Miyata; J Am Soc Nephrol 16: 3631-3641. [Abstract] [Full Text] [PDF]

Hyperaldosteronemia and Activation of the Epithelial Sodium Channel Are Not Required for Sodium Retention in Puromycin-Induced Nephrosis: Stéphane Lourdel, Johannes Loffing, Guillaume Favre, Marc Paulais, Antoine Nissant, Panos Fakitsas, Christophe Créminon, Eric Féraille, François Verrey, Jacques Teulon, Alain Doucet, and Georges Deschênes; J Am Soc Nephrol 16: 3642-3650. [Abstract] [Full Text] [PDF]

IL-10 Suppresses Chemokines, Inflammation, and Fibrosis in a Model of Chronic Renal Disease: Wei Mu, Xiaosen Ouyang, Anupam Agarwal, Li Zhang, David A. Long, Pedro E. Cruz, Carlos A. Roncal, Olena Y. Glushakova, Vince A. Chiodo, Mark A. Atkinson, William W. Hauswirth, Terry R. Flotte, Bernardo Rodriguez-Iturbe, and Richard J. Johnson; J Am Soc Nephrol 16: 3651-3660. [Abstract] [Full Text] [PDF]

Basic Transplantation:

MHC Class II–Mediated Apoptosis by a Nonpolymorphic MHC Class II Peptide Proceeds by Activation of Protein Kinase C: Weiping Zang, Safa Kalache, Marvin Lin, Bernd Schroppel, and Barbara Murphy; J Am Soc Nephrol 16: 3661-3668. [Abstract] [Full Text] [PDF]

Disease of the Month:

Hantavirus Infection: Walter Muranyi, Udo Bahr, Martin Zeier, and Fokko J. van der Woude; J Am Soc Nephrol 16: 3669-3679. [Full Text] [PDF]

Clinical Nephrology:

Renal Apolipoprotein A-I Amyloidosis: A Rare and Usually Ignored Cause of Hereditary Tubulointerstitial Nephritis: Gina Gregorini, Claudia Izzi, Laura Obici, Regina Tardanico, Christoph Röcken, Battista Fabio Viola, Mariano Capistrano, Simona Donadei, Luciano Biasi, Tiziano Scalvini, Giampaolo Merlini, and Francesco Scolari; J Am Soc Nephrol 16: 3680-3686. [Abstract] [Full Text] [PDF]

Skin Autofluorescence, a Measure of Cumulative Metabolic Stress and Advanced Glycation End Products, Predicts Mortality in Hemodialysis Patients: Robbert Meerwaldt, Jasper W.L. Hartog, Reindert Graaff, Roel J. Huisman, Thera P. Links, Nynke C. den Hollander, Susan R. Thorpe, John W. Baynes, Gerjan Navis, Rijk O.B. Gans, and Andries J. Smit; J Am Soc Nephrol 16: 3687-3693. [Abstract] [Full Text] [PDF]

Human Genetics:

Mutational and Biological Analysis of ${alpha}$ -Actinin-4 in Focal Segmental Glomerulosclerosis: Astrid Weins, Peter Kenlan, Stephanie Herbert, Tu C. Le, Ivan Villegas, Bernard S. Kaplan, Gerald B. Appel, and Martin R. Pollak; J Am Soc Nephrol 16: 3694-3701. [Abstract] [Full Text] [PDF]

Epidemiology and Outcomes:

Microalbuminuria and Coronary Heart Disease Risk in an Ethnically Diverse UK Population: A Prospective Cohort Study: Therese Tillin, Nita Forouhi, Paul McKeigue, and Nish Chaturvedi; J Am Soc Nephrol 16: 3702-3710. [Abstract] [Full Text] [PDF]

Differential Mortality and Transplantation Rates among Asians and Pacific Islanders with ESRD: Yoshio N. Hall, Jared G. Sugihara, Alan S. Go, and Glenn M. Chertow; J Am Soc Nephrol 16: 3711-3720. [Abstract] [Full Text] [PDF]

Cystatin C and Subclinical Brain Infarction: Stephen L. Seliger, W.T. Longstreth, Jr, Ronit Katz, Teri Manolio, Linda F. Fried, Michael Shlipak, Catherine O. Stehman-Breen, Anne Newman, Mark Sarnak, Daniel L. Gillen, Anthony Bleyer, and David S. Siscovick; J Am Soc Nephrol 16: 3721-3727. [Abstract] [Full Text] [PDF]

Kidney Function as a Predictor of Noncardiovascular Mortality: Linda F. Fried, Ronit Katz, Mark J. Sarnak, Michael G. Shlipak, Paulo H.M. Chaves, Nancy Swords Jenny, Catherine Stehman-Breen, Dan Gillen, Anthony J. Bleyer, Calvin Hirsch, David Siscovick, and Anne B. Newman; J Am Soc Nephrol 16: 3728-3735. [Abstract] [Full Text] [PDF]

Projecting the Number of Patients with End-Stage Renal Disease in the United States to the Year 2015: David T. Gilbertson, Jiannong Liu, Jay L. Xue, Thomas A. Louis, Craig A. Solid, James P. Ebben, and Allan J. Collins; J Am Soc Nephrol 16: 3736-3741. [Abstract] [Full Text] [PDF]

Clinical Dialysis:

${kappa}$ -Opioid System in Uremic Pruritus: Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Studies: Björn Wikström, Ryszard Gellert, Søren D. Ladefoged, Yasuaki Danda, Masahiko Akai, Kaoru Ide, Midori Ogasawara, Yoshiharu Kawashima, Koki Ueno, Akio Mori, and Yuji Ueno; J Am Soc Nephrol 16: 3742-3747. [Abstract] [Full Text] [PDF]

Chronic Kidney Disease:

Effect of Pravastatin in People with Diabetes and Chronic Kidney Disease: Marcello Tonelli, Anthony Keech, Jim Shepherd, Frank Sacks, Andrew Tonkin, Chris Packard, Marc Pfeffer, John Simes, Chris Isles, Curt Furberg, Malcolm West, Tim Craven, and Gary Curhan; J Am Soc Nephrol 16: 3748-3754. [Abstract] [Full Text] [PDF]

Clinical Transplantation:

Rapamycin for Treatment of Chronic Allograft Nephropathy in Renal Transplant Patients: Giovanni Stallone, Barbara Infante, Antonio Schena, Michele Battaglia, Pasquale Ditonno, Antonia Loverre, Loreto Gesualdo, Francesco Paolo Schena, and Giuseppe Grandaliano; J Am Soc Nephrol 16: 3755-3762. [Abstract] [Full Text] [PDF]

Estimating Glomerular Filtration Rate in Kidney Transplantation: A Comparison between Serum Creatinine and Cystatin C–Based Methods: Christine White, Ayub Akbari, Naser Hussain, Laurent Dinh, Guido Filler, Nathalie Lepage, and Greg A. Knoll; J Am Soc Nephrol 16: 3763-3770. [Abstract] [Full Text] [PDF]

Expression of Surfactant Protein-C, S100A8, S100A9, and B Cell Markers in Renal Allografts: Investigation of the Prognostic Value: Michael Eikmans, Marian C. Roos-van Groningen, Yvo W.J. Sijpkens, Jan Ehrchen, Johannes Roth, Hans J. Baelde, Ingeborg M. Bajema, Johan W. de Fijter, Emile de Heer, and Jan A. Bruijn; J Am Soc Nephrol 16: 3771-3786. [Abstract] [Full Text] [PDF]

Acknowledgments:

ACKNOWLEDGMENT OF MANUSCRIPT CONSULTANTS: JASN Volume 16: J Am Soc Nephrol 16: 3787-3790. [Full Text] [PDF]

Announcements:

Announcements: J Am Soc Nephrol 16: 3791. [Full Text] [PDF]

ASN News:

ASN News: J Am Soc Nephrol 16: A20-A21. [Full Text]