THIS MONTH'S HIGHLIGHTS:

This Month’s Highlights

J Am Soc Nephrol 16: 565-566 [Full Text] [PDF]  

BASIC SCIENCE:

Cell and Transport Physiology:

Modulation of Hypertonicity-Induced Aquaporin-1 by Sodium Chloride, Urea, Betaine, and Heat Shock in Murine Renal Medullary Cells

Fuminori Umenishi, Shigemi Yoshihara, Takefumi Narikiyo, and Robert W. Schrier

J Am Soc Nephrol 16: 600-607 First Published on January 12, 2005; 10.1681/ASN.2004030241 [Abstract] [Full Text] [PDF]  

Renal Tubular Reabsorption of Folate Mediated by Folate Binding Protein 1

Henrik Birn, Ofer Spiegelstein, Erik I. Christensen, and Richard H. Finnell

J Am Soc Nephrol 16: 608-615 First Published on February 9, 2005; 10.1681/ASN.2004080711 [Abstract] [Full Text] [PDF]  

Cell Biology:

Heterogenous Nuclear Ribonucleoprotein F Modulates Angiotensinogen Gene Expression in Rat Kidney Proximal Tubular Cells

Chih-Chang Wei, Deng-Fu Guo, Shao-Ling Zhang, Julie R. Ingelfinger, and John S.D. Chan

J Am Soc Nephrol 16: 616-628 First Published on January 19, 2005; 10.1681/ASN.2004080715 [Abstract] [Full Text] [PDF]  

Nephrotic Plasma Alters Slit Diaphragm–Dependent Signaling and Translocates Nephrin, Podocin, and CD2 Associated Protein in Cultured Human Podocytes

Richard J.M. Coward, Rebecca R. Foster, David Patton, Lan Ni, Rachel Lennon, David O. Bates, Steven J. Harper, Peter W. Mathieson, and Moin A. Saleem

J Am Soc Nephrol 16: 629-637 First Published on January 19, 2005; 10.1681/ASN.2004030172 [Abstract] [Full Text] [PDF]  

Pioglitazone Inhibits Cell Growth and Reduces Matrix Production in Human Kidney Fibroblasts

Stephen Zafiriou, Scott R. Stanners, Sonia Saad, Tania S. Polhill, Philip Poronnik, and Carol A. Pollock

J Am Soc Nephrol 16: 638-645 First Published on February 2, 2005; 10.1681/ASN.2004040278 [Abstract] [Full Text] [PDF]  

Knockdown of Fibronectin Induces Mitochondria-Dependent Apoptosis in Rat Mesangial Cells

Di Wu, XiangMei Chen, DengFu Guo, Quan Hong, Bo Fu, Rui Ding, LiFang Yu, Kai Hou, Zhe Feng, XiaoJie Zhang, and JianZhong Wang

J Am Soc Nephrol 16: 646-657 First Published on January 26, 2005; 10.1681/ASN.2004060445 [Abstract] [Full Text] [PDF]  

Mobilization of Bone Marrow Cells by G-CSF Rescues Mice from Cisplatin-Induced Renal Failure, and M-CSF Enhances the Effects of G-CSF

Masayoshi Iwasaki, Yasushi Adachi, Keizo Minamino, Yasuhiro Suzuki, Yuming Zhang, Mitsuhiko Okigaki, Keiji Nakano, Yasushi Koike, Jianfeng Wang, Hiromi Mukaide, Shigeru Taketani, Yasukiyo Mori, Hakuo Takahashi, Toshiji Iwasaka, and Susumu Ikehara

J Am Soc Nephrol 16: 658-666 First Published on February 2, 2005; 10.1681/ASN.2004010067 [Abstract] [Full Text] [PDF]  

Role of Reactive Oxygen Species in TGF-1-Induced Mitogen-Activated Protein Kinase Activation and Epithelial-Mesenchymal Transition in Renal Tubular Epithelial Cells

Dong Young Rhyu, Yanqiang Yang, Hunjoo Ha, Geun Taek Lee, Jae Sook Song, Soo-taek Uh, and Hi Bahl Lee

J Am Soc Nephrol 16: 667-675 First Published on January 26, 2005; 10.1681/ASN.2004050425 [Abstract] [Full Text] [PDF]  

Genetics and Development:

Expression and Phenotype Analysis of the Nephrocystin-1 and Nephrocystin-4 Homologs in Caenorhabditis elegans

Matthias T.F. Wolf, Jeeyong Lee, Franziska Panther, Edgar A. Otto, Kun-Liang Guan, and Friedhelm Hildebrandt

J Am Soc Nephrol 16: 676-687 First Published on January 19, 2005; 10.1681/ASN.2003121025 [Abstract] [Full Text] [PDF]  

Hemodynamics and Vascular Regulation:

Mechanical Stretch Induces Monocyte Chemoattractant Activity via an NF-B-Dependent Monocyte Chemoattractant Protein-1-Mediated Pathway in Human Mesangial Cells: Inhibition by Rosiglitazone

Gabriella Gruden, Giorgia Setti, Anthea Hayward, David Sugden, Sara Duggan, Davina Burt, Robin E. Buckingham, Luigi Gnudi, and Giancarlo Viberti

J Am Soc Nephrol 16: 688-696 First Published on January 26, 2005; 10.1681/ASN.2004030251 [Abstract] [Full Text] [PDF]  

Basic Immunology and Pathology:

Cisplatin Nephrotoxicity Is Mediated by Deoxyribonuclease I

Alexei G. Basnakian, Eugene O. Apostolov, Xiaoyan Yin, Markus Napirei, Hans Georg Mannherz, and Sudhir V. Shah

J Am Soc Nephrol 16: 697-702 First Published on January 12, 2005; 10.1681/ASN.2004060494 [Abstract] [Full Text] [PDF]  

Pathophysiology of Renal Disease and Progression:

Temporary Angiotensin II Blockade at the Prediabetic Stage Attenuates the Development of Renal Injury in Type 2 Diabetic Rats

Yukiko Nagai, Li Yao, Hiroyuki Kobori, Kayoko Miyata, Yuri Ozawa, Akira Miyatake, Tokihito Yukimura, Takatomi Shokoji, Shoji Kimura, Hideyasu Kiyomoto, Masakazu Kohno, Youichi Abe, and Akira Nishiyama

J Am Soc Nephrol 16: 703-711 First Published on January 12, 2005; 10.1681/ASN.2004080649 [Abstract] [Full Text] [PDF]  

Mice Lacking the 110-kD Isoform of Poly(ADP-Ribose) Glycohydrolase Are Protected against Renal Ischemia/Reperfusion Injury

Nimesh S.A. Patel, Ulrich Cortes, Rosanna Di Poala, Emanuela Mazzon, Helder Mota-Filipe, Salvatore Cuzzocrea, Zhao-Qi Wang, and Christoph Thiemermann

J Am Soc Nephrol 16: 712-719 First Published on January 26, 2005; 10.1681/ASN.2004080677 [Abstract] [Full Text] [PDF]  

T Cells Modulate Neutrophil-Dependent Acute Renal Failure during Endotoxemia: Critical Role for CD28

Kai Singbartl, Susanne Große Bockhorn, Alexander Zarbock, Mirco Schmolke, and Hugo Van Aken

J Am Soc Nephrol 16: 720-728 First Published on February 2, 2005; 10.1681/ASN.2004050381 [Abstract] [Full Text] [PDF]  

CLINICAL SCIENCE:

Clinical Nephrology:

Ultradian but not Circadian Blood Pressure Rhythms Correlate with Renal Dysfunction in Children with Chronic Renal Failure

Elke Wühl, Charlotte Hadtstein, Otto Mehls, Franz Schaefer, and the ESCAPE Trial Group

J Am Soc Nephrol 16: 746-754 First Published on January 12, 2005; 10.1681/ASN.2004070537 [Abstract] [Full Text] [PDF]  

Human Genetics:

Progressive Loss of Renal Function Is an Age-Dependent Heritable Trait in Type 1 Autosomal Dominant Polycystic Kidney Disease

Andrew D. Paterson, Riccardo Magistroni, Ning He, Kairong Wang, Ann Johnson, Pamela R. Fain, Elizabeth Dicks, Patrick Parfrey, Peter St. George-Hyslop, and York Pei

J Am Soc Nephrol 16: 755-762 First Published on January 26, 2005; 10.1681/ASN.2004090758 [Abstract] [Full Text] [PDF]  

Chronic Kidney Disease:

Predictive Performance of the Modification of Diet in Renal Disease and Cockcroft-Gault Equations for Estimating Renal Function

Marc Froissart, Jerome Rossert, Christian Jacquot, Michel Paillard, and Pascal Houillier

J Am Soc Nephrol 16: 763-773 First Published on January 19, 2005; 10.1681/ASN.2004070549 [Abstract] [Full Text] [PDF]  

Epidemiology and Outcomes:

Suicide in the United States End-Stage Renal Disease Program

Manjula Kurella, Paul L. Kimmel, Belinda S. Young, and Glenn M. Chertow

J Am Soc Nephrol 16: 774-781 First Published on January 19, 2005; 10.1681/ASN.2004070550 [Abstract] [Full Text] [PDF]  

Survival Advantage of Hispanic Patients Initiating Dialysis in the United States Is Modified by Race

Bhamidipati V.R. Murthy, Donald A. Molony, and Austin G. Stack

J Am Soc Nephrol 16: 782-790 First Published on January 26, 2005; 10.1681/ASN.2004080627 [Abstract] [Full Text] [PDF]  

Risk Factors for Development of Decreased Kidney Function in a Southeast Asian Population: A 12-Year Cohort Study

Somnuek Domrongkitchaiporn, Piyamitr Sritara, Chagriya Kitiyakara, Wasana Stitchantrakul, Vorasakdi Krittaphol, Porntip Lolekha, Sayan Cheepudomwit, and Tada Yipintsoi

J Am Soc Nephrol 16: 791-799 First Published on January 26, 2005; 10.1681/ASN.2004030208 [Abstract] [Full Text] [PDF]  

Human Mineral Metabolism and Bone Disease:

Cinacalcet HCl, an Oral Calcimimetic Agent for the Treatment of Secondary Hyperparathyroidism in Hemodialysis and Peritoneal Dialysis: A Randomized, Double-Blind, Multicenter Study

Jill S. Lindberg, Bruce Culleton, Gordon Wong, Michael F. Borah, Roderick V. Clark, Warren B. Shapiro, Simon D. Roger, Fred E. Husserl, Preston S. Klassen, Matthew D. Guo, Moetaz B. Albizem, and Jack W. Coburn

J Am Soc Nephrol 16: 800-807 First Published on February 2, 2005; 10.1681/ASN.2004060512 [Abstract] [Full Text] [PDF]  

Clinical Transplantation:

Cardiovascular Events and Investigation in Patients Who Are Awaiting Cadaveric Kidney Transplantation

John S. Gill, Irene Ma, David Landsberg, Nathan Johnson, and Adeera Levin

J Am Soc Nephrol 16: 808-816 First Published on February 2, 2005; 10.1681/ASN.2004090810 [Abstract] [Full Text] [PDF]  

Predictors of Renal Allograft Histologic Damage Progression

Fernanda Ortiz, Timo Paavonen, Tom Törnroth, Petri Koskinen, Patrik Finne, Kaija Salmela, Lauri Kyllönen, Carola Grönhagen-Riska, and Eero Honkanen

J Am Soc Nephrol 16: 817-824 First Published on February 2, 2005; 10.1681/ASN.2004060475 [Abstract] [Full Text] [PDF]  

Nephrology beyond JASN:

Why Less Diabetes with Blockade of the Renin-Angiotensin System?: Evidence for a Local Angiotensin-Generating System and Dose-Dependent Inhibition of Glucose-Stimulated Insulin Release by Angiotensin II in Isolated Pancreatic Islets. Diabetologia 47: 240–248, 2004

T. Lau, P.-O. Carlsson, P.S. Leung, C. Wolfrum, E. Asilmaz, E. Luca, J.M. Friedman, M. Stoffel, J.C. Verhave, H.L. Hillege, J.G.M. Burgerhof, W.M.T. Janssen, R.T. Gansevoort, G.J. Navis, D. de Zeeuw, P.E. de Jong for the PREVEND Study Group

J Am Soc Nephrol 16: 567-573 [Full Text] [PDF]  

Editorial:

Type 2 Diabetic Nephropathy: Never too Early to Treat?

Karl F. Hilgers and Roland Veelken

J Am Soc Nephrol 16: 574-575 First Published on February 9, 2005; 10.1681/ASN.2005010083 [Full Text] [PDF]  

Presidential Address:

2004 Presidential Address: An Evaluation of Progress toward Goals

William E. Mitch

J Am Soc Nephrol 16: 576-582 First Published on January 26, 2005; 10.1681/ASN.2004110977 [Full Text] [PDF]  

Review:

Establishing the Role of Angiotensin-Converting Enzyme in Renal Function and Blood Pressure Control through the Analysis of Genetically Modified Mice

Kenneth E. Bernstein, Hong D. Xiao, Jon W. Adams, Kristen Frenzel, Ping Li, Xiao Z. Shen, Justin M. Cole, and Sebastien Fuchs

J Am Soc Nephrol 16: 583-591 First Published on January 19, 2005; 10.1681/ASN.2004080693 [Full Text] [PDF]  

Special Commentary:

Renin Inhibition: What Are the Therapeutic Opportunities?

Naomi D.L. Fisher and Norman K. Hollenberg

J Am Soc Nephrol 16: 592-599 First Published on February 9, 2005; 10.1681/ASN.2004100874 [Abstract] [Full Text] [PDF]  

Disease of the Month:

Genetic Hypercalciuria

Orson W. Moe and Olivier Bonny

J Am Soc Nephrol 16: 729-745 First Published on February 2, 2005; 10.1681/ASN.2004100888 [Abstract] [Full Text] [PDF]  

Announcements:

Announcements

J Am Soc Nephrol 16: 825 [Full Text] [PDF]  

ERRATA:

Erratum

J Am Soc Nephrol 16: 826 [Full Text] [PDF]  

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