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Contents: Volume 16, Issue 4, April 2005   [Index by Author] 
      THIS MONTH'S HIGHLIGHTS
      BASIC SCIENCE
            Cell and Transport Physiology
            Cell Biology
            Genetics and Development
            Basic Mineral Metabolism
            Hemodynamics and Vascular Regulation
            Basic Immunology and Pathology
            Pathophysiology of Renal Disease and Progression
            Basic Dialysis
      CLINICAL SCIENCE
            Clinical Nephrology
            Human Genetics
            Epidemiology and Outcomes
            Clinical Dialysis
            Clinical Immunology and Pathology
            Chronic Kidney Disease
      ASN News
      Nephrology beyond JASN
      Editorials
      FastTrack
      2004 Young Investigator Award Lecture
      Review
      Disease of the Month
      Announcements
      Errata
 
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THIS MONTH'S HIGHLIGHTS:

This Month’s Highlights
J Am Soc Nephrol 16: 827-828 [Full Text] [PDF]  

BASIC SCIENCE:

Cell and Transport Physiology:

Induction and Targeting of the Glutamine Transporter SN1 to the Basolateral Membranes of Cortical Kidney Tubule Cells during Chronic Metabolic Acidosis Suggest a Role in pH Regulation
Tom Tallak Solbu, Jean-Luc Boulland, Wasim Zahid, May Kristin Lyamouri Bredahl, Mahmood Amiry-Moghaddam, Jon Storm-Mathisen, Bjørg Åse Roberg, and Farrukh A. Chaudhry
J Am Soc Nephrol 16: 869-877 First Published on February 16, 2005; 10.1681/ASN.2004060433 [Abstract] [Full Text] [PDF]  

Mineralocorticoid versus Glucocorticoid Receptor Occupancy Mediating Aldosterone-Stimulated Sodium Transport in a Novel Renal Cell Line
Hans-Peter Gaeggeler, Elena Gonzalez-Rodriguez, Nicole Fowler Jaeger, Dominique Loffing-Cueni, Rikke Norregaard, Johannes Loffing, Jean-Daniel Horisberger, and Bernard C. Rossier
J Am Soc Nephrol 16: 878-891 First Published on March 2, 2005; 10.1681/ASN.2004121110 [Abstract] [Full Text] [PDF]  

Cell Biology:

Erythropoietin Increases Asymmetric Dimethylarginine in Endothelial Cells: Role of Dimethylarginine Dimethylaminohydrolase
Fortunato Scalera, Jan T. Kielstein, Jens Martens-Lobenhoffer, Sylvia C. Postel, Michael Täger, and Stefanie M. Bode-Böger
J Am Soc Nephrol 16: 892-898 First Published on February 23, 2005; 10.1681/ASN.2004090735 [Abstract] [Full Text] [PDF]  

Role of ERK1/2 and p38 Mitogen-Activated Protein Kinases in the Regulation of Thrombospondin-1 by TGF-{beta}1 in Rat Proximal Tubular Cells and Mouse Fibroblasts
Takahiko Nakagawa, Hui Y. Lan, Olena Glushakova, Hong J. Zhu, Duk-Hee Kang, George F. Schreiner, Erwin P. Böttinger, Richard J. Johnson, and Yuri Y. Sautin
J Am Soc Nephrol 16: 899-904 First Published on February 16, 2005; 10.1681/ASN.2004080689 [Abstract] [Full Text] [PDF]  

Genetics and Development:

Kinesin Family Member 12 Is a Candidate Polycystic Kidney Disease Modifier in the cpk Mouse
Michal Mrug, Renhua Li, Xiangqin Cui, Trenton R. Schoeb, Gary A. Churchill, and Lisa M. Guay-Woodford
J Am Soc Nephrol 16: 905-916 First Published on February 23, 2005; 10.1681/ASN.2004121083 [Abstract] [Full Text] [PDF]  

Basic Mineral Metabolism:

Low Turnover Osteodystrophy and Vascular Calcification Are Amenable to Skeletal Anabolism in an Animal Model of Chronic Kidney Disease and the Metabolic Syndrome
Matthew R. Davies, Richard. J. Lund, Suresh Mathew, and Keith A. Hruska
J Am Soc Nephrol 16: 917-928 First Published on March 2, 2005; 10.1681/ASN.2004100835 [Abstract] [Full Text] [PDF]  

Daily or Intermittent Calcitriol Administration during Growth Hormone Therapy in Rats with Renal Failure and Advanced Secondary Hyperparathyroidism
Cheryl P. Sanchez and Yu-Zhu He
J Am Soc Nephrol 16: 929-938 First Published on February 23, 2005; 10.1681/ASN.2003100878 [Abstract] [Full Text] [PDF]  

Hemodynamics and Vascular Regulation:

Role of the Renin-Angiotensin System on the Parathyroid Hormone–Related Protein Overexpression Induced by Nephrotoxic Acute Renal Failure in the Rat
Arantxa Ortega, David Rámila, Adriana Izquierdo, Laura González, Antonio Barat, Rosa Gazapo, Ricardo J. Bosch, and Pedro Esbrit
J Am Soc Nephrol 16: 939-949 First Published on February 23, 2005; 10.1681/ASN.2004040328 [Abstract] [Full Text] [PDF]  

Protective Effect of Carbon Monoxide–Releasing Compounds in Ischemia-Induced Acute Renal Failure
Trinity Vera, Jeffery R. Henegar, Heather A. Drummond, John M. Rimoldi, and David E. Stec
J Am Soc Nephrol 16: 950-958 First Published on February 23, 2005; 10.1681/ASN.2004090736 [Abstract] [Full Text] [PDF]  

Reduced Agonist-Induced Endothelium-Dependent Vasodilation in Uremia Is Attributable to an Impairment of Vascular Nitric Oxide
Jens Passauer, Frank Pistrosch, Eckhart Büssemaker, Grit Lässig, Kay Herbrig, and Peter Gross
J Am Soc Nephrol 16: 959-965 First Published on February 23, 2005; 10.1681/ASN.2004070582 [Abstract] [Full Text] [PDF]  

Basic Immunology and Pathology:

Regression of Glomerulosclerosis with High-Dose Angiotensin Inhibition Is Linked to Decreased Plasminogen Activator Inhibitor-1
Li-Jun Ma, Shinya Nakamura, Jean Claude Aldigier, Michele Rossini, Haichun Yang, Xiubin Liang, Ikuko Nakamura, Carmelita Marcantoni, and Agnes B. Fogo
J Am Soc Nephrol 16: 966-976 First Published on February 23, 2005; 10.1681/ASN.2004060492 [Abstract] [Full Text] [PDF]  

Delayed Chemokine Receptor 1 Blockade Prolongs Survival in Collagen 4A3–Deficient Mice with Alport Disease
Volha Ninichuk, Oliver Gross, Christoph Reichel, Andrej Khandoga, Rahul D. Pawar, Raluca Ciubar, Stephan Segerer, Emilia Belemezova, Ewa Radomska, Bruno Luckow, Guillermo Perez de Lema, Philip M. Murphy, Ji-Liang Gao, Anna Henger, Matthias Kretzler, Richard Horuk, Manfred Weber, Fritz Krombach, Detlef Schlöndorff, and Hans-Joachim Anders
J Am Soc Nephrol 16: 977-985 First Published on February 16, 2005; 10.1681/ASN.2004100871 [Abstract] [Full Text] [PDF]  

Vasodilator-Stimulated Phosphoprotein–Deficient Mice Demonstrate Increased Platelet Activation but Improved Renal Endothelial Preservation and Regeneration in Passive Nephrotoxic Nephritis
Bernd Hohenstein, Laura Kasperek, Dieter-Johannes Kobelt, Christoph Daniel, Stepan Gambaryan, Thomas Renné, Ulrich Walter, Kerstin U. Amann, and Christian P.M. Hugo
J Am Soc Nephrol 16: 986-996 First Published on March 2, 2005; 10.1681/ASN.2004070591 [Abstract] [Full Text] [PDF]  

Intrarenal Injection of Bone Marrow-Derived Angiogenic Cells Reduces Endothelial Injury and Mesangial Cell Activation in Experimental Glomerulonephritis
Hideki Uchimura, Takeshi Marumo, Osamu Takase, Hiroshi Kawachi, Fujio Shimizu, Matsuhiko Hayashi, Takao Saruta, Keiichi Hishikawa, and Toshiro Fujita
J Am Soc Nephrol 16: 997-1004 First Published on March 2, 2005; 10.1681/ASN.2004050367 [Abstract] [Full Text] [PDF]  

Pathophysiology of Renal Disease and Progression:

Effects of Proteasome Inhibition on the Kidney in Experimental Hypercholesterolemia
Alejandro R. Chade, Joerg Herrmann, Xiangyang Zhu, James D. Krier, Amir Lerman, and Lilach O. Lerman
J Am Soc Nephrol 16: 1005-1012 First Published on February 16, 2005; 10.1681/ASN.2004080674 [Abstract] [Full Text] [PDF]  

Genetic Engineering of Glomerular Sclerosis in the Mouse via Control of Onset and Severity of Podocyte-Specific Injury
Taiji Matsusaka, Jing Xin, Suguri Niwa, Kazuto Kobayashi, Akira Akatsuka, Hiroomi Hashizume, Qing-cheng Wang, Ira Pastan, Agnes B. Fogo, and Iekuni Ichikawa
J Am Soc Nephrol 16: 1013-1023 First Published on March 9, 2005; 10.1681/ASN.2004080720 [Abstract] [Full Text] [PDF]  

Basic Dialysis:

Effect of Chymase Inhibition on the Arteriovenous Fistula Stenosis in Dogs
Denan Jin, Haruhiko Ueda, Shinji Takai, Yukiko Okamoto, Michiko Muramatsu, Masato Sakaguchi, Nobuhisa Shibahara, Yoji Katsuoka, and Mizuo Miyazaki
J Am Soc Nephrol 16: 1024-1034 First Published on March 2, 2005; 10.1681/ASN.2003121009 [Abstract] [Full Text] [PDF]  

CLINICAL SCIENCE:

Clinical Nephrology:

An Alternative Formula to the Cockcroft-Gault and the Modification of Diet in Renal Diseases Formulas in Predicting GFR in Individuals with Type 1 Diabetes
Hassan Ibrahim, Michael Mondress, Abel Tello, Ying Fan, Joseph Koopmeiners, and William Thomas
J Am Soc Nephrol 16: 1051-1060 First Published on February 16, 2005; 10.1681/ASN.2004080692 [Abstract] [Full Text] [PDF]  

Focal and Segmental Glomerulosclerosis: Definition and Relevance of a Partial Remission
Stéphan Troyanov, Catherine A. Wall, Judith A. Miller, James W. Scholey, Daniel C. Cattran for the Toronto Glomerulonephritis Registry Group
J Am Soc Nephrol 16: 1061-1068 First Published on February 16, 2005; 10.1681/ASN.2004070593 [Abstract] [Full Text] [PDF]  

Aortic Pulse Wave Velocity and Albuminuria in Patients with Type 2 Diabetes
Andrew Smith, Janaka Karalliedde, Lorenita De Angelis, David Goldsmith, and Giancarlo Viberti
J Am Soc Nephrol 16: 1069-1075 First Published on March 2, 2005; 10.1681/ASN.2004090769 [Abstract] [Full Text] [PDF]  

Long-Term Study of Mycophenolate Mofetil as Continuous Induction and Maintenance Treatment for Diffuse Proliferative Lupus Nephritis
Tak-Mao Chan, Kai-Chung Tse, Colin Siu-On Tang, Mo-Yin Mok, Fu-Keung Li for the Hong Kong Nephrology Study Group
J Am Soc Nephrol 16: 1076-1084 First Published on February 23, 2005; 10.1681/ASN.2004080686 [Abstract] [Full Text] [PDF]  

Human Genetics:

T-786C Polymorphism of the Endothelial Nitric Oxide Synthase Gene Is Associated with Albuminuria in the Diabetes Heart Study
Yongmei Liu, Kathryn P. Burdon, Carl D. Langefeld, Stephanie R. Beck, Lynne E. Wagenknecht, Stephen S. Rich, Donald W. Bowden, and Barry I. Freedman
J Am Soc Nephrol 16: 1085-1090 First Published on March 2, 2005; 10.1681/ASN.2004100817 [Abstract] [Full Text] [PDF]  

Epidemiology and Outcomes:

Renal Insulin Resistance Syndrome, Adiponectin and Cardiovascular Events in Patients with Kidney Disease: The Mild and Moderate Kidney Disease Study
Bjoern Becker, Florian Kronenberg, Jan T. Kielstein, Hermann Haller, Christian Morath, Eberhard Ritz, Danilo Fliser for the MMKD Study Group
J Am Soc Nephrol 16: 1091-1098 First Published on March 2, 2005; 10.1681/ASN.2004090742 [Abstract] [Full Text] [PDF]  

Clinical Dialysis:

In Vivo Modulation of Soluble "Antagonistic" IL-6 Receptor Synthesis and Release in ESRD
Bruno Memoli, Giuseppe Grandaliano, Michela Soccio, Loredana Postiglione, Brunella Guida, Vincenzo Bisesti, Pasquale Esposito, Alfredo Procino, Daniela Marrone, Ashour Michael, Michele Andreucci, Francesco Paolo Schena, and Giovanni Pertosa
J Am Soc Nephrol 16: 1099-1107 First Published on February 16, 2005; 10.1681/ASN.2004080628 [Abstract] [Full Text] [PDF]  

Thrombophilia and the Risk for Hemodialysis Vascular Access Thrombosis
Greg A. Knoll, Philip S. Wells, Darlene Young, Sherry L. Perkins, Rachel M. Pilkey, Jennifer J. Clinch, and Marc A. Rodger
J Am Soc Nephrol 16: 1108-1114 First Published on February 23, 2005; 10.1681/ASN.2004110999 [Abstract] [Full Text] [PDF]  

Activated Injectable Vitamin D and Hemodialysis Survival: A Historical Cohort Study
Ming Teng, Myles Wolf, M. Norma Ofsthun, J. Michael Lazarus, Miguel A. Hernán, Carlos A. Camargo, Jr, and Ravi Thadhani
J Am Soc Nephrol 16: 1115-1125 First Published on February 23, 2005; 10.1681/ASN.2004070573 [Abstract] [Full Text] [PDF]  

Clinical Immunology and Pathology:

Human Kidney Injury Molecule-1 Is a Tissue and Urinary Tumor Marker of Renal Cell Carcinoma
Won K. Han, Anwar Alinani, Chin-Lee Wu, Dror Michaelson, Massimo Loda, Francis J. McGovern, Ravi Thadhani, and Joseph V. Bonventre
J Am Soc Nephrol 16: 1126-1134 First Published on March 2, 2005; 10.1681/ASN.2004070530 [Abstract] [Full Text] [PDF]  

Chronic Kidney Disease:

Chronic Angiotensin II Receptor Blockade Reduces (Intra)Renal Vascular Resistance in Patients with Type 2 Diabetes
Danilo Fliser, Kathrin-Kristin Wagner, Astrid Loos, Dimitrios Tsikas, and Hermann Haller
J Am Soc Nephrol 16: 1135-1140 First Published on February 16, 2005; 10.1681/ASN.2004100852 [Abstract] [Full Text] [PDF]  

High Prevalence of Occult Coronary Artery Stenosis in Patients with Chronic Kidney Disease at the Initiation of Renal Replacement Therapy: An Angiographic Examination
Takayasu Ohtake, Shuzo Kobayashi, Hidekazu Moriya, Kousuke Negishi, Kouji Okamoto, Kyoko Maesato, and Shigeru Saito
J Am Soc Nephrol 16: 1141-1148 First Published on March 2, 2005; 10.1681/ASN.2004090765 [Abstract] [Full Text] [PDF]  

ASN News:

ASN News
J Am Soc Nephrol 16: A17-A18 [Full Text] [PDF]  

Nephrology beyond JASN:

Immunoregulation in Urinary Tract Inflammation—A Role of Tamm-Horsfall Glycoprotein: Tamm-Horsfall Glycoprotein Links Innate Immune Cell Activation with Adaptive Immunity via a Toll-Like Receptor-4–Dependent Mechanism. J Clin Invest 115: 468–475, 2005
MD Säemann, T Weichhart, M Zeyda, G Staffler, M Schunn, KM Stuhlmeier, Y Sobanov, TM Stulnig, S Akira, A von Gabain, U von Ahsen, WH Horl, GJ Zlabinger, T. Tanaka, T. Miyata, R. Inagi, T. Fujita, M. Nangaku, M Desvarieux, RT Demmer, T Rundek, B Boden-Albala, DR Jacobs, Jr, RL Sacco, and PN Papapanou
J Am Soc Nephrol 16: 829-836 [Full Text] [PDF]  

Editorials:

Uniform Clinical Trial Registration Policy for Journals of Kidney Diseases, Dialysis, and Transplantation
William G. Couser, Tilman Drueke, Phillip Halloran, Bertram Kasiske, Saulo Klahr, and Peter Morris
J Am Soc Nephrol 16: 837 First Published on March 2, 2005; 10.1681/ASN.2005010036 [Full Text] [PDF]  

V2 Receptor Antagonists in Cystic Kidney Diseases: An Exciting Step towards a Practical Treatment
William M. Bennett
J Am Soc Nephrol 16: 838-839 First Published on February 23, 2005; 10.1681/ASN.2005020136 [Full Text] [PDF]  

Is Regression of Chronic Nephropathies a Therapeutic Target?
Giuseppe Remuzzi and Andrea Remuzzi
J Am Soc Nephrol 16: 840-842 First Published on March 16, 2005; 10.1681/ASN.2005020171 [Full Text] [PDF]  

Cardiovascular Risk Evaluation before Kidney Transplantation
Steven Fishbane
J Am Soc Nephrol 16: 843-845 First Published on March 16, 2005; 10.1681/ASN.2005020189 [Full Text] [PDF]  

FastTrack:

Effectiveness of Vasopressin V2 Receptor Antagonists OPC-31260 and OPC-41061 on Polycystic Kidney Disease Development in the PCK Rat
Xiaofang Wang, Vincent Gattone, II, Peter C. Harris, and Vicente E. Torres
J Am Soc Nephrol 16: 846-851 First Published on February 23, 2005; 10.1681/ASN.2004121090 [Abstract] [Full Text] [PDF]  

Rf-2 Gene Modulates Proteinuria and Albuminuria Independently of Changes in Glomerular Permeability in the Fawn-Hooded Hypertensive Rat
Artur Rangel-Filho, Mukut Sharma, Yvonne H. Datta, Carol Moreno, Richard J. Roman, Yoshiki Iwamoto, Abraham P. Provoost, Jozef Lazar, and Howard J. Jacob
J Am Soc Nephrol 16: 852-856 First Published on March 9, 2005; 10.1681/ASN.2005010029 [Full Text] [PDF]  

2004 Young Investigator Award Lecture:

Building the Glomerulus: A Matricentric View
Jeffrey H. Miner
J Am Soc Nephrol 16: 857-861 First Published on February 23, 2005; 10.1681/ASN.2004121139 [Full Text] [PDF]  

Review:

Does Hemodialysis Increase Protein Breakdown? Dissociation between Whole-Body Amino Acid Turnover and Regional Muscle Kinetics
Victoria S. Lim, T. Alp Ikizler, Dominic S.C. Raj, and Michael J. Flanigan
J Am Soc Nephrol 16: 862-868 First Published on February 16, 2005; 10.1681/ASN.2004080624 [Abstract] [Full Text] [PDF]  

Disease of the Month:

Hemolytic Uremic Syndrome
Marina Noris and Giuseppe Remuzzi
J Am Soc Nephrol 16: 1035-1050 First Published on February 23, 2005; 10.1681/ASN.2004100861 [Full Text] [PDF]  

Announcements:

Announcements
J Am Soc Nephrol 16: 1149 [Full Text] [PDF]  

Errata:

Errata
J Am Soc Nephrol 16: 1150 [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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