JASN -- Table of Contents (17 [1])

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THIS MONTH'S HIGHLIGHTS:

This Month’s Highlights: J Am Soc Nephrol 17: 1-2. [Full Text] [PDF]

Nephrology beyond JASN:

Accessory Renal Arteries—Mostly, But Not Always, Innocuous: Renin-Dependent Hypertension Caused by Nonfocal Stenotic Aberrant Renal Arteries—Proof of a New Syndrome. Hypertension 46: 380–385, 2005: Kem D.C., Lyons D.F., Wenzl J., Halverstadt D., Yu X, Titze J., Bauer K., Schafflhuber M., Dietsch P., Lang R., Schwind K.H., Luft F.C., Eckhardt K.-U., Hilgers K.F, Barnoya J., and Glantz S.A.; J Am Soc Nephrol 17: 3-11. [Full Text] [PDF]

Editorials:

Renal Therapy by Stem Cells: Outsource or In-House?: Dale R. Abrahamson and Brooke M. Steenhard; J Am Soc Nephrol 17: 12-14. [Full Text] [PDF]

Thinking about Rare Kidney Diseases: James A. Shayman; J Am Soc Nephrol 17: 15-16. [Full Text] [PDF]

Review:

Chronic Hypoxia and Tubulointerstitial Injury: A Final Common Pathway to End-Stage Renal Failure: Masaomi Nangaku; J Am Soc Nephrol 17: 17-25. [Abstract] [Full Text] [PDF]

Fast Track:

Identification of BSPRY as a Novel Auxiliary Protein Inhibiting TRPV5 Activity: Stan F.J. van de Graaf, Annemiete W.C.M. van der Kemp, Dennis van den Berg, Mijke van Oorschot, Joost G.J. Hoenderop, and René J.M. Bindels; J Am Soc Nephrol 17: 26-30. [Abstract] [Full Text] [PDF] [Data Supplement]

Cell and Transport Physiology:

Contrary to Rat-Type, Human-Type Na,K-ATPase Is Phosphorylated at the Same Amino Acid by Hormones that Produce Opposite Effects on Enzyme Activity: Riad Efendiev and Carlos H. Pedemonte; J Am Soc Nephrol 17: 31-38. [Abstract] [Full Text] [PDF]

Aquaporin-1 Facilitates Epithelial Cell Migration in Kidney Proximal Tubule: Mariko Hara-Chikuma and A.S. Verkman; J Am Soc Nephrol 17: 39-45. [Abstract] [Full Text] [PDF] [Supplemental Material]

Prostaglandin E₂ Inhibits Its Own Renal Transport by Downregulation of Organic Anion Transporters rOAT1 and rOAT3: Christoph Sauvant, Hildegard Holzinger, and Michael Gekle; J Am Soc Nephrol 17: 46-53. [Abstract] [Full Text] [PDF]

Cell Biology:

Hepatocyte Growth Factor Is a Downstream Effector that Mediates the Antifibrotic Action of Peroxisome Proliferator–Activated Receptor- ${gamma}$ Agonists: Yingjian Li, Xiaoyan Wen, Bradley C. Spataro, Kebin Hu, Chunsun Dai, and Youhua Liu; J Am Soc Nephrol 17: 54-65. [Abstract] [Full Text] [PDF]

Type IV Collagen Induces Podocytic Features in Bone Marrow Stromal Stem Cells In Vitro: Julie Perry, Stephanie Tam, Keqin Zheng, Yoshikazu Sado, Howard Dobson, Barbara Jefferson, Robert Jacobs, and Paul S. Thorner; J Am Soc Nephrol 17: 66-76. [Abstract] [Full Text] [PDF]

Three-Dimensional Reconstruction of the Mouse Nephron: Xiao-Yue Zhai, Jesper S. Thomsen, Henrik Birn, Inger B. Kristoffersen, Arne Andreasen, and Erik I. Christensen; J Am Soc Nephrol 17: 77-88. [Abstract] [Full Text] [PDF]

Identification of Novel Protein Targets for Modification by 15-Deoxy- ${Delta}$ ^12,14-Prostaglandin J₂ in Mesangial Cells Reveals Multiple Interactions with the Cytoskeleton: Konstantinos Stamatakis, Francisco J. Sánchez-Gómez, and Dolores Pérez-Sala; J Am Soc Nephrol 17: 89-98. [Abstract] [Full Text] [PDF]

Src Activation of NF- ${kappa}$ B Augments IL-1 ${beta}$ –Induced Nitric Oxide Production in Mesangial Cells: Diane I. Jalal and Bruce C. Kone; J Am Soc Nephrol 17: 99-106. [Abstract] [Full Text] [PDF]

Basic Mineral Metabolism:

Increased Parathyroid Hormone Gene Expression in Secondary Hyperparathyroidism of Experimental Uremia Is Reversed by Calcimimetics: Correlation with Posttranslational Modification of the Trans Acting Factor AUF1: Ronen Levi, Iddo Z. Ben-Dov, Vardit Lavi-Moshayoff, Maya Dinur, David Martin, Tally Naveh-Many, and Justin Silver; J Am Soc Nephrol 17: 107-112. [Abstract] [Full Text] [PDF]

Genetics and Development:

Ghrelin Improves Renal Function in Mice with Ischemic Acute Renal Failure: Ryo Takeda, Hiroaki Nishimatsu, Etsu Suzuki, Hiroshi Satonaka, Daisuke Nagata, Shigeyoshi Oba, Masataka Sata, Masao Takahashi, Yuji Yamamoto, Yasuo Terauchi, Takashi Kadowaki, Kenji Kangawa, Tadaichi Kitamura, Ryozo Nagai, and Yasunobu Hirata; J Am Soc Nephrol 17: 113-121. [Abstract] [Full Text] [PDF]

Basic Immunology and Pathology:

Inducible Co-Stimulator Null MRL-Fas^lpr Mice: Uncoupling of Autoantibodies and T Cell Responses in Lupus: Geraldine C. Zeller, Junichi Hirahashi, Andreas Schwarting, Arlene H. Sharpe, and Vicki R. Kelley; J Am Soc Nephrol 17: 122-130. [Abstract] [Full Text] [PDF]

Tissue-Type Plasminogen Activator Modulates Inflammatory Responses and Renal Function in Ischemia Reperfusion Injury: Joris J.T.H. Roelofs, Kasper M.A. Rouschop, Jaklien C. Leemans, Nike Claessen, Anita M. de Boer, Wilma M. Frederiks, H.Roger Lijnen, Jan J. Weening, and Sandrine Florquin; J Am Soc Nephrol 17: 131-140. [Abstract] [Full Text] [PDF]

Toll-Like Receptor-7 Modulates Immune Complex Glomerulonephritis: Rahul D. Pawar, Prashant S. Patole, Daniel Zecher, Stephan Segerer, Matthias Kretzler, Detlef Schlöndorff, and Hans-Joachim Anders; J Am Soc Nephrol 17: 141-149. [Abstract] [Full Text] [PDF]

A Pathogenetic Role for Mast Cells in Experimental Crescentic Glomerulonephritis: Jennifer R. Timoshanko, Richard Kitching, Timothy J. Semple, Peter G. Tipping, and Stephen R. Holdsworth; J Am Soc Nephrol 17: 150-159. [Abstract] [Full Text] [PDF]

Therapeutic Effect of Anti–TNF- ${alpha}$ Antibodies in an Experimental Model of Anti-Neutrophil Cytoplasm Antibody–Associated Systemic Vasculitis: Mark A. Little, Gurjeet Bhangal, C. Lucy Smyth, Marian T. Nakada, H. Terence Cook, Sussan Nourshargh, and Charles D. Pusey; J Am Soc Nephrol 17: 160-169. [Abstract] [Full Text] [PDF]

Factor H and Atypical Hemolytic Uremic Syndrome: Mutations in the C-Terminus Cause Structural Changes and Defective Recognition Functions: Mihály Józsi, Stefan Heinen, Andrea Hartmann, Clemens W. Ostrowicz, Steffi Hälbich, Heiko Richter, Anja Kunert, Christoph Licht, Rebecca E. Saunders, Stephen J. Perkins, Peter F. Zipfel, and Christine Skerka; J Am Soc Nephrol 17: 170-177. [Abstract] [Full Text] [PDF]

Pathophysiology of Renal Disease and Progression:

Calcium Restores a Normal Proliferation Phenotype in Human Polycystic Kidney Disease Epithelial Cells: Tamio Yamaguchi, Scott J. Hempson, Gail A. Reif, Anne-Marie Hedge, and Darren P. Wallace; J Am Soc Nephrol 17: 178-187. [Abstract] [Full Text] [PDF]

Adult Kidney Tubular Cell Population Showing Phenotypic Plasticity, Tubulogenic Capacity, and Integration Capability into Developing Kidney: Akito Maeshima, Hiroyuki Sakurai, and Sanjay K. Nigam; J Am Soc Nephrol 17: 188-198. [Abstract] [Full Text] [PDF]

Basic Dialysis:

Damage to the Peritoneal Membrane by Glucose Degradation Products Is Mediated by the Receptor for Advanced Glycation End-Products: Vedat Schwenger, Christian Morath, Alexander Salava, Kerstin Amann, Yuri Seregin, Reinhold Deppisch, Eberhard Ritz, Angelika Bierhaus, Peter P. Nawroth, and Martin Zeier; J Am Soc Nephrol 17: 199-207. [Abstract] [Full Text] [PDF]

Disease of the Month:

Familial Hyperkalemic Hypertension: Juliette Hadchouel, Céline Delaloy, Sébastien Fauré, Jean-Michel Achard, and Xavier Jeunemaitre; J Am Soc Nephrol 17: 208-217. [Full Text] [PDF]

Clinical Nephrology:

Left Ventricular Geometry in Children with Mild to Moderate Chronic Renal Insufficiency: Maria Chiara Matteucci, Elke Wühl, Stefano Picca, Antonio Mastrostefano, Gabriele Rinelli, Carmela Romano, Gianfranco Rizzoni, Otto Mehls, Giovanni de Simone, Franz Schaefer ESCAPE Trial Group; J Am Soc Nephrol 17: 218-226. [Abstract] [Full Text] [PDF]

The Heart of Children with Steroid-Resistant Nephrotic Syndrome: Is It All Podocin?: Yaacov Frishberg, Sofia Feinstein, Choni Rinat, Rachel Becker-Cohen, Israela Lerer, Annick Raas-Rothschild, Benjamin Ferber, and Amiram Nir; J Am Soc Nephrol 17: 227-231. [Abstract] [Full Text] [PDF]

Human Genetics:

Pharmacologic Chaperones as a Potential Treatment for X-Linked Nephrogenic Diabetes Insipidus: Virginie Bernier, Jean-Pierre Morello, Alexandro Zarruk, Nicolas Debrand, Ali Salahpour, Michèle Lonergan, Marie-Françoise Arthus, André Laperrière, Rémi Brouard, Michel Bouvier, and Daniel G. Bichet; J Am Soc Nephrol 17: 232-243. [Abstract] [Full Text] [PDF]

Epidemiology and Outcomes:

Kidney Function and Mortality among Patients with Left Ventricular Systolic Dysfunction: Nadia A. Khan, Irene Ma, Christopher R. Thompson, Karin Humphries, Deeb N. Salem, Mark J. Sarnak, and Adeera Levin; J Am Soc Nephrol 17: 244-253. [Abstract] [Full Text] [PDF]

Cystatin C and Mortality Risk in the Elderly: The Health, Aging, and Body Composition Study: Michael G. Shlipak, Christina L. Wassel Fyr, Glenn M. Chertow, Tamara B. Harris, Stephen B. Kritchevsky, Frances A. Tylavsky, Suzanne Satterfield, Steven R. Cummings, Anne B. Newman, and Linda F. Fried; J Am Soc Nephrol 17: 254-261. [Abstract] [Full Text] [PDF]

Plasma Osteoprotegerin Is Associated with Mortality in Hemodialysis Patients: Marion Morena, Nathalie Terrier, Isabelle Jaussent, Hélène Leray-Moragues, Lotfi Chalabi, Jean-Pierre Rivory, François Maurice, Cécile Delcourt, Jean-Paul Cristol, Bernard Canaud, and Anne-Marie Dupuy; J Am Soc Nephrol 17: 262-270. [Abstract] [Full Text] [PDF]

Higher Peritoneal Transport Status Is Associated with Higher Mortality and Technique Failure in the Australian and New Zealand Peritoneal Dialysis Patient Populations: Markus Rumpsfeld, Stephen P. McDonald, and David W. Johnson; J Am Soc Nephrol 17: 271-278. [Abstract] [Full Text] [PDF]

Low Hemoglobin, Chronic Kidney Disease, and Risk for Coronary Heart Disease–Related Death: The Blue Mountains Eye Study: Stephen R. Leeder, Paul Mitchell, Gerald Liew, Elena Rochtchina, Wayne Smith, and Jie Jin Wang; J Am Soc Nephrol 17: 279-284. [Abstract] [Full Text] [PDF]

Clinical Dialysis:

Anthropometric Prediction of Total Body Water in Children Who Are on Pediatric Peritoneal Dialysis: Bruce Z. Morgenstern, Elke Wühl, K. Sreekumaran Nair, Bradley A. Warady, and Franz Schaefer; J Am Soc Nephrol 17: 285-293. [Abstract] [Full Text] [PDF]

Clinical Transplantation:

Phenotypically and Functionally Distinct CD8⁺ Lymphocyte Populations in Long-Term Drug-Free Tolerance and Chronic Rejection in Human Kidney Graft Recipients: Dominique Baeten, Stéphanie Louis, Christophe Braud, Cécile Braudeau, Caroline Ballet, Frédéric Moizant, Annaik Pallier, Magali Giral, Sophie Brouard, and Jean-Paul Soulillou; J Am Soc Nephrol 17: 294-304. [Abstract] [Full Text] [PDF]

No Difference in Degree of Interstitial Sirius Red–Stained Area in Serial Biopsies from Area under Concentration-over-Time Curves–Guided Cyclosporine versus Tacrolimus-Treated Renal Transplant Recipients at One Year: Ajda T. Rowshani, Eduard M. Scholten, Frederike Bemelman, Michael Eikmans, Mirza Idu, Marian C.R. van Groningen, Janto S. Surachno, Marko J.K. Mallat, Leendert C. Paul, Johan W. de Fijter, Ingeborg M. Bajema, Ineke ten Berge, and Sandrine Florquin; J Am Soc Nephrol 17: 305-312. [Abstract] [Full Text] [PDF]

Announcements:

Announcements: J Am Soc Nephrol 17: 313. [Full Text] [PDF]

Errata:

Errata: J Am Soc Nephrol 17: 314. [Full Text] [PDF]

ASN News:

ASN News: J Am Soc Nephrol 17: A25-A27. [Full Text] [PDF]