JASN -- Table of Contents (17 [11])

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This Month's Highlights:

This Month’s Highlights: J Am Soc Nephrol 17: 2947-2948. [Full Text] [PDF]

Nephrology beyond JASN:

Vitamin D₃–Triggered Antimicrobial Response—Another Pleiotropic Effect beyond Mineral and Bone Metabolism: Toll-Like Receptor Triggering of a Vitamin D–Mediated Human Antimicrobial Response. Science 311: 1770–1773, 2006: P.T. Liu, S. Stenger, H. Li, L. Wenzel, B.H. Tan, S.R. Krutzik, M.T. Ochoa, J. Schauber, K. Wu, C. Meinken, D.L. Kamen, M. Wagner, R. Bals, A. Steinmeyer, U. Zugel, R.L. Gallo, D. Eisenberg, M. Hewison, B.W. Hollis, J.S. Adams, B.R. Bloom, and R.L. Modlin; J Am Soc Nephrol 17: 2949-2953. [Full Text] [PDF]

Editorials:

Who Wins the Competition: TRPV5 or Calbindin-D_28K?: Eberhard Schlatter; J Am Soc Nephrol 17: 2954-2956. [Full Text] [PDF]

ACE2: A New Target for Prevention of Diabetic Nephropathy?: Julie R. Ingelfinger; J Am Soc Nephrol 17: 2957-2959. [Full Text] [PDF]

An Emerging Role for Relaxin as a Renal Vasodilator: Jennifer M Sasser, Marshall D. Lindheimer, and Chris Baylis; J Am Soc Nephrol 17: 2960-2961. [Full Text] [PDF]

Anemia after Kidney Transplantation: Time for Action: Joshua J. Augustine and Donald E. Hricik; J Am Soc Nephrol 17: 2962-2963. [Full Text] [PDF]

Frontiers in Nephrology:

Chronic Kidney Disease Progression: Allison A. Eddy and Eric G. Neilson; J Am Soc Nephrol 17: 2964-2966. [Full Text] [PDF]

The Chronic Kidney Disease Epidemic: Stepping Back and Looking Forward: Bryce Kiberd; J Am Soc Nephrol 17: 2967-2973. [Abstract] [Full Text] [PDF]

How Does Proteinuria Cause Progressive Renal Damage?: Mauro Abbate, Carla Zoja, and Giuseppe Remuzzi; J Am Soc Nephrol 17: 2974-2984. [Abstract] [Full Text] [PDF]

Renin-Angiotensin-Aldosterone System and Progression of Renal Disease: Christiane Rüster and Gunter Wolf; J Am Soc Nephrol 17: 2985-2991. [Abstract] [Full Text] [PDF]

Renal Fibroblasts and Myofibroblasts in Chronic Kidney Disease: Frank Strutz and Michael Zeisberg; J Am Soc Nephrol 17: 2992-2998. [Full Text] [PDF]

Plasminogen Activator Inhibitor-1 in Chronic Kidney Disease: Evidence and Mechanisms of Action: Allison A. Eddy and Agnes B. Fogo; J Am Soc Nephrol 17: 2999-3012. [Full Text] [PDF]

Fast Track:

Cyst Number but Not the Rate of Cystic Growth Is Associated with the Mutated Gene in Autosomal Dominant Polycystic Kidney Disease: Peter C. Harris, Kyongtae T. Bae, Sandro Rossetti, Vicente E. Torres, Jared J. Grantham, Arlene B. Chapman, Lisa M. Guay-Woodford, Bernard F. King, Louis H. Wetzel, Deborah A. Baumgarten, Philip J. Kenney, Mark Consugar, Saulo Klahr, William M. Bennett, Catherine M. Meyers, Qin (Jean) Zhang, Paul A. Thompson, Fang Zhu, J. Philip Miller, and and the CRISP Consortium; J Am Soc Nephrol 17: 3013-3019. [Abstract] [Full Text] [PDF]

Cell and Transport Physiology:

Critical Role of the Epithelial Ca²⁺ Channel TRPV5 in Active Ca²⁺ Reabsorption as Revealed by TRPV5/Calbindin-D_28K Knockout Mice: Dimitra Gkika, Yu-Juei Hsu, Annemiete W. van der Kemp, Sylvia Christakos, René J. Bindels, and Joost G. Hoenderop; J Am Soc Nephrol 17: 3020-3027. [Abstract] [Full Text] [PDF]

Cell Biology:

Isolation and Characterization of Kidney-Derived Stem Cells: Sandeep Gupta, Catherine Verfaillie, David Chmielewski, Stefan Kren, Keith Eidman, Jeffrey Connaire, Yves Heremans, Troy Lund, Mark Blackstad, Yuehua Jiang, Aernout Luttun, and Mark E. Rosenberg; J Am Soc Nephrol 17: 3028-3040. [Abstract] [Full Text] [PDF]

Role of Parathyroid Hormone in the Downregulation of Liver Cytochrome P450 in Chronic Renal Failure: Josée Michaud, Judith Naud, Jérôme Chouinard, François Désy, Francois A. Leblond, Karine Desbiens, Alain Bonnardeaux, and Vincent Pichette; J Am Soc Nephrol 17: 3041-3048. [Abstract] [Full Text] [PDF]

Stable Knockdown of Polycystin-1 Confers Integrin- ${alpha}$ 2 $beta$ 1–Mediated Anoikis Resistance: Lorenzo Battini, Elena Fedorova, Salvador Macip, Xiaohong Li, Patricia D. Wilson, and G. Luca Gusella; J Am Soc Nephrol 17: 3049-3058. [Abstract] [Full Text] [PDF]

Hemodynamics and Vascular Regulation:

Renal Damage after Myocardial Infarction Is Prevented by Renin-Angiotensin-Aldosterone-System Intervention: Willemijn A.K.M. Windt, Wouter B.A. Eijkelkamp, Robert H. Henning, Alex C.A. Kluppel, Pieter A. de Graeff, Hans L. Hillege, Stefan Schäfer, Dick de Zeeuw, and Richard P.E. van Dokkum; J Am Soc Nephrol 17: 3059-3066. [Abstract] [Full Text] [PDF]

Glomerular Localization and Expression of Angiotensin-Converting Enzyme 2 and Angiotensin-Converting Enzyme: Implications for Albuminuria in Diabetes: Minghao Ye, Jan Wysocki, Josette William, Maria José Soler, Ivan Cokic, and Daniel Batlle; J Am Soc Nephrol 17: 3067-3075. [Abstract] [Full Text] [PDF]

Influence of Recombinant Human Relaxin on Renal Hemodynamics in Healthy Volunteers: Marie C. Smith, Lee. A. Danielson, Kirk. P. Conrad, and John M. Davison; J Am Soc Nephrol 17: 3192-3197. [Abstract] [Full Text] [PDF]

Basic Immunology and Pathology:

A Nephritogenic Peptide Induces Intermolecular Epitope Spreading on Collagen IV in Experimental Autoimmune Glomerulonephritis: Lanlin Chen, Thomas Hellmark, Vadim Pedchenko, Billy G. Hudson, Charles D. Pusey, Jay W. Fox, and W. Kline Bolton; J Am Soc Nephrol 17: 3076-3081. [Abstract] [Full Text] [PDF]

Pathophysiology of Renal Disease and Progression:

Heat Preconditioning Attenuates Renal Injury in Ischemic ARF in Rats: Role of Heat-Shock Protein 70 on NF- ${kappa}$ B–Mediated Inflammation and on Tubular Cell Injury: Sang-Kyung Jo, Gang Jee Ko, Chang Su Boo, Won Yong Cho, and Hyoung Kyu Kim; J Am Soc Nephrol 17: 3082-3092. [Abstract] [Full Text] [PDF]

Blockade of Vascular Endothelial Growth Factor Signaling Ameliorates Diabetic Albuminuria in Mice: Sun Hee Sung, Fuad N. Ziyadeh, Amy Wang, Petr E. Pyagay, Yashpal S. Kanwar, and Sheldon Chen; J Am Soc Nephrol 17: 3093-3104. [Abstract] [Full Text] [PDF]

Signaling Mechanism of Renal Fibrosis in Unilateral Ureteral Obstructive Kidney Disease in ROCK1 Knockout Mice: Ping Fu, Fang Liu, Spencer Su, Wansheng Wang, Xiao R. Huang, Mark L. Entman, Robert J. Schwartz, Lei Wei, and Hui Y. Lan; J Am Soc Nephrol 17: 3105-3114. [Abstract] [Full Text] [PDF]

Ischemic Preconditioning Provides Both Acute and Delayed Protection against Renal Ischemia and Reperfusion Injury in Mice: Jin Deok Joo, Mihwa Kim, Vivette D. D’Agati, and H. Thomas Lee; J Am Soc Nephrol 17: 3115-3123. [Abstract] [Full Text] [PDF]

Acute Uremia but Not Renal Inflammation Attenuates Aseptic Acute Lung Injury: A Critical Role for Uremic Neutrophils: Alexander Zarbock, Mirco Schmolke, Tilman Spieker, Kerstin Jurk, Hugo Van Aken, and Kai Singbartl; J Am Soc Nephrol 17: 3124-3131. [Abstract] [Full Text] [PDF]

Clinical Nephrology:

Survival by Dialysis Modality in Critically Ill Patients with Acute Kidney Injury: Kerry C. Cho, Jonathan Himmelfarb, Emil Paganini, T. Alp Ikizler, Sharon H. Soroko, Ravindra L. Mehta, and Glenn M. Chertow; J Am Soc Nephrol 17: 3132-3138. [Abstract] [Full Text] [PDF]

Repetitive Fragmentation Products of Albumin and ${alpha}$ 1-Antitrypsin in Glomerular Diseases Associated with Nephrotic Syndrome: Giovanni Candiano, Luca Musante, Maurizio Bruschi, Andrea Petretto, Laura Santucci, Piero Del Boccio, Barbara Pavone, Francesco Perfumo, Andrea Urbani, Francesco Scolari, and Gian Marco Ghiggeri; J Am Soc Nephrol 17: 3139-3148. [Abstract] [Full Text] [PDF]

Intradialytic Oral Nutrition Improves Protein Homeostasis in Chronic Hemodialysis Patients with Deranged Nutritional Status: Lara B. Pupim, Karen M. Majchrzak, Paul J. Flakoll, and T. Alp Ikizler; J Am Soc Nephrol 17: 3149-3157. [Abstract] [Full Text] [PDF]

Human Genetics:

Functional Variants in the Lymphotoxin- ${alpha}$ Gene Predict Cardiovascular Disease in Dialysis Patients: Yongmei Liu, Yvette Berthier-Schaad, Laura Plantinga, Nancy E. Fink, Russell P. Tracy, Wen Hong Kao, Michael J. Klag, Michael W. Smith, and Josef Coresh; J Am Soc Nephrol 17: 3158-3166. [Abstract] [Full Text] [PDF]

Increased Apoptosis in Cystinotic Fibroblasts and Renal Proximal Tubule Epithelial Cells Results from Cysteinylation of Protein Kinase C ${delta}$: Margaret A. Park, Vojislav Pejovic, Kathryn G. Kerisit, Sacha Junius, and Jess G. Thoene; J Am Soc Nephrol 17: 3167-3175. [Abstract] [Full Text] [PDF]

Apparent Mineralocorticoid Excess: Report of Six New Cases and Extensive Personal Experience: Gilles Morineau, Véronique Sulmont, Remi Salomon, Beatrice Fiquet-Kempf, Xavier Jeunemaître, Jérôme Nicod, and Paolo Ferrari; J Am Soc Nephrol 17: 3176-3184. [Abstract] [Full Text] [PDF]

Major Histocompatibility Complex HLA Region Largely Explains the Genetic Variance Exercised on Neutrophil Membrane Proteinase 3 Expression: Sibylle von Vietinghoff, Andreas Busjahn, Constanze Schönemann, Gero Massenkeil, Björn Otto, Friedrich C. Luft, and Ralph Kettritz; J Am Soc Nephrol 17: 3185-3191. [Abstract] [Full Text] [PDF]

Epidemiology and Outcomes:

Efficacy of the World Health Organization Analgesic Ladder to Treat Pain in End-Stage Renal Disease: Ahmad S. Barakzoy and Alvin H. Moss; J Am Soc Nephrol 17: 3198-3203. [Abstract] [Full Text] [PDF]

Clinical Dialysis:

Risk Equation Determining Unsuccessful Cannulation Events and Failure to Maturation in Arteriovenous Fistulas (REDUCE FTM I): Charmaine E. Lok, Michael Allon, Louise Moist, Matthew J. Oliver, Hemal Shah, and Deborah Zimmerman; J Am Soc Nephrol 17: 3204-3212. [Abstract] [Full Text] [PDF]

Human Mineral Metabolism:

Partial Neutralization of the Acidogenic Western Diet with Potassium Citrate Increases Bone Mass in Postmenopausal Women with Osteopenia: Sigrid Jehle, Antonella Zanetti, Jürgen Muser, Henry N. Hulter, and Reto Krapf; J Am Soc Nephrol 17: 3213-3222. [Abstract] [Full Text] [PDF]

Chronic Kidney Disease:

Relationship between Moderate to Severe Kidney Disease and Hip Fracture in the United States: Thomas L. Nickolas, Donald J. McMahon, and Elizabeth Shane; J Am Soc Nephrol 17: 3223-3232. [Abstract] [Full Text] [PDF]

Development of a Diagnostic Method for Detecting Increased Muscle Protein Degradation in Patients with Catabolic Conditions: Biruh T. Workeneh, Helbert Rondon-Berrios, Liping Zhang, Zhaoyong Hu, Gashu Ayehu, Arny Ferrando, Joel D. Kopple, Huiyun Wang, Thomas Storer, Mario Fournier, Seoung Woo Lee, Jie Du, and William E. Mitch; J Am Soc Nephrol 17: 3233-3239. [Abstract] [Full Text] [PDF]

Clinical Transplantation:

Posttransplantation Anemia at 12 Months in Kidney Recipients Treated with Mycophenolate Mofetil: Risk Factors and Implications for Mortality: Anikphe E. Imoagene-Oyedeji, Sylvia E. Rosas, Alden M. Doyle, Simin Goral, and Roy D. Bloom; J Am Soc Nephrol 17: 3240-3247. [Abstract] [Full Text] [PDF]

Proteomic Analysis of Urine in Kidney Transplant Patients with BK Virus Nephropathy: Timo Jahnukainen, David Malehorn, Mai Sun, James Lyons-Weiler, William Bigbee, Gaurav Gupta, Ron Shapiro, Parmjeet Singh Randhawa, Richard Pelikan, Milos Hauskrecht, and Abhay Vats; J Am Soc Nephrol 17: 3248-3256. [Abstract] [Full Text] [PDF]

No Improvement of Patient or Graft Survival in Transplant Recipients Treated with Angiotensin-Converting Enzyme Inhibitors or Angiotensin II Type 1 Receptor Blockers: A Collaborative Transplant Study Report: Gerhard Opelz, Martin Zeier, Gunter Laux, Christian Morath, and Bernd Döhler; J Am Soc Nephrol 17: 3257-3262. [Abstract] [Full Text] [PDF]

Announcements:

Announcements: J Am Soc Nephrol 17: 3263. [Full Text] [PDF]

Errata:

Erratum: J Am Soc Nephrol 17: 3264. [Full Text] [PDF]

ASN News:

ASN News: J Am Soc Nephrol 17: A25-A26. [Full Text] [PDF]