JASN -- Table of Contents (17 [12])

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This Month's Highlights:

This Month’s Highlights: J Am Soc Nephrol 17: 3265-3266. [Full Text] [PDF]

Nephrology beyond JASN:

Faulty Podocyte Hypoxia Sensing—A Novel Pathway for Rapidly Progressive Glomerulonephritis: Loss of the Tumor Suppressor Vhlh Leads to Upregulation of Cxcr4 and Rapidly Progressive Glomerulonephritis. Nat Med 12: 1081–1087, 2006: M. Ding, S. Cui, C. Li, S. Jothy, V. Haase, B. Steer, P. Marsden, J. Pippin, S. Shankland, M. Rastaldi, C. Cohen, M. Kretzler, S. Quaggin, M. Chromek, Z. Slamová, P. Bergman, L. Kovács, L. Podracká, I. Ehrén, T. Hökfelt, G. Gudmundsson, R. Gallo, B. Agerberth, and A. Brauner; J Am Soc Nephrol 17: 3267-3272. [Full Text] [PDF]

Editorials:

Lupus Nephritis: Toll the Trigger!: Kelly D. Smith; J Am Soc Nephrol 17: 3273-3275. [Full Text] [PDF]

Prevention of Microalbuminuria in Type 2 Diabetes: Millimeters or Milligrams?: Richard J. Glassock; J Am Soc Nephrol 17: 3276-3278. [Full Text] [PDF]

Sleep Apnea with Intermittent Hemodialysis: Time for a Wake-Up Call!: Christopher T. Chan; J Am Soc Nephrol 17: 3279-3280. [Full Text] [PDF]

Reviews:

mRNA Translation: Unexplored Territory in Renal Science: Balakuntalam S. Kasinath, Meenalakshmi M. Mariappan, Kavithalakshmi Sataranatarajan, Myung Ja Lee, and Denis Feliers; J Am Soc Nephrol 17: 3281-3292. [Abstract] [Full Text] [PDF]

Fast Track:

Prorenin and Angiotensin-Dependent Renal Vasoconstriction in Type 1 and Type 2 Diabetes: Ana R. Stankovic, Naomi D.L. Fisher, and Norman K. Hollenberg; J Am Soc Nephrol 17: 3293-3299. [Abstract] [Full Text] [PDF]

Cell Biology:

Isolation and Characterization of Nontubular Sca-1⁺Lin^– Multipotent Stem/Progenitor Cells from Adult Mouse Kidney: Benjamin Dekel, Lior Zangi, Elias Shezen, Shlomit Reich-Zeliger, Smadar Eventov-Friedman, Helena Katchman, Jasmin Jacob-Hirsch, Ninette Amariglio, Gideon Rechavi, Raanan Margalit, and Yair Reisner; J Am Soc Nephrol 17: 3300-3314. [Abstract] [Full Text] [PDF]

Smoking Induces Glomerulosclerosis in Aging Estrogen-Deficient Mice through Cross-Talk between TGF- $beta$ 1 and IGF-I Signaling Pathways: Sharon J. Elliot, Michael Karl, Mariana Berho, Xiaomei Xia, Simone Pereria-Simon, Diego Espinosa-Heidmann, and Gary E. Striker; J Am Soc Nephrol 17: 3315-3324. [Abstract] [Full Text] [PDF]

Role of the Akt/FoxO3a Pathway in TGF- $beta$ 1–Mediated Mesangial Cell Dysfunction: A Novel Mechanism Related to Diabetic Kidney Disease: Mitsuo Kato, Hang Yuan, Zhong-Gao Xu, Linda Lanting, Shu-Lian Li, Mei Wang, Mickey C.-T. Hu, Marpadga A. Reddy, and Rama Natarajan; J Am Soc Nephrol 17: 3325-3335. [Abstract] [Full Text] [PDF]

Apoptosis Antagonizing Transcription Factor Protects Renal Tubule Cells against Oxidative Damage and Apoptosis Induced by Ischemia-Reperfusion: Jun Xie and Qing Guo; J Am Soc Nephrol 17: 3336-3346. [Abstract] [Full Text] [PDF]

Hemodynamics and Vascular Regulation:

$beta$ ₁ Receptors Protect the Renal Afferent Arteriole of Angiotensin-Infused Rabbits from Norepinephrine-Induced Oxidative Stress: Dan Wang, Pedro Jose, and Christopher S. Wilcox; J Am Soc Nephrol 17: 3347-3354. [Abstract] [Full Text] [PDF]

Basic Immunology and Pathology:

Bone Marrow–Derived Cells Are Sufficient and Necessary Targets to Mediate Glomerulonephritis and Vasculitis Induced by Anti-Myeloperoxidase Antibodies: Adrian Schreiber, Hong Xiao, Ronald J. Falk, and J. Charles Jennette; J Am Soc Nephrol 17: 3355-3364. [Abstract] [Full Text] [PDF]

Ligands to Nucleic Acid–Specific Toll-Like Receptors and the Onset of Lupus Nephritis: Rahul D. Pawar, Prashant S. Patole, Andreas Ellwart, Maciej Lech, Stephan Segerer, Detlef Schlondorff, and Hans-Joachim Anders; J Am Soc Nephrol 17: 3365-3373. [Abstract] [Full Text] [PDF]

Pathophysiology of Renal Disease and Progression:

Discoidin Domain Receptor 1 Null Mice Are Protected against Hypertension-Induced Renal Disease: Martin Flamant, Sandrine Placier, Anita Rodenas, Cyrile Anne Curat, Wolfgang F. Vogel, Christos Chatziantoniou, and Jean-Claude Dussaule; J Am Soc Nephrol 17: 3374-3381. [Abstract] [Full Text] [PDF]

Paricalcitol Attenuates Renal Interstitial Fibrosis in Obstructive Nephropathy: Xiaoyue Tan, Yingjian Li, and Youhua Liu; J Am Soc Nephrol 17: 3382-3393. [Abstract] [Full Text] [PDF] [Data Supplement]

Endothelin-A Receptor Blockade Improves Renal Microvascular Architecture and Function in Experimental Hypercholesterolemia: Alejandro R. Chade, James D. Krier, Stephen C. Textor, Amir Lerman, and Lilach O. Lerman; J Am Soc Nephrol 17: 3394-3403. [Abstract] [Full Text] [PDF]

A Murine Model of HUS: Shiga Toxin with Lipopolysaccharide Mimics the Renal Damage and Physiologic Response of Human Disease: Tiffany R. Keepers, Mitchell A. Psotka, Lisa K. Gross, and Tom G. Obrig; J Am Soc Nephrol 17: 3404-3414. [Abstract] [Full Text] [PDF] [Data Supplement]

Calpain Activation and Secretion Promote Glomerular Injury in Experimental Glomerulonephritis: Evidence from Calpastatin-Transgenic Mice: Julie Peltier, Agnès Bellocq, Joëlle Perez, Sophie Doublier, Yi-Chun Xu Dubois, Jean-Philippe Haymann, Giovanni Camussi, and Laurent Baud; J Am Soc Nephrol 17: 3415-3423. [Abstract] [Full Text] [PDF]

Early Embryonic Renal Tubules of Wild-Type and Polycystic Kidney Disease Kidneys Respond to cAMP Stimulation with Cystic Fibrosis Transmembrane Conductance Regulator/Na⁺,K⁺,2Cl^– Co-Transporter–Dependent Cystic Dilation: Brenda S. Magenheimer, Patricia L. St. John, Kathryn S. Isom, Dale R. Abrahamson, Robert C. De Lisle, Darren P. Wallace, Robin L. Maser, Jared J. Grantham, and James P. Calvet; J Am Soc Nephrol 17: 3424-3437. [Abstract] [Full Text] [PDF]

Enhanced Aldosterone Signaling in the Early Nephropathy of Rats with Metabolic Syndrome: Possible Contribution of Fat-Derived Factors: Miki Nagase, Shigetaka Yoshida, Shigeru Shibata, Takashi Nagase, Takanari Gotoda, Katsuyuki Ando, and Toshiro Fujita; J Am Soc Nephrol 17: 3438-3446. [Abstract] [Full Text] [PDF]

Basic Dialysis:

Novel Role for Mast Cells in Omental Tissue Remodeling and Cell Recruitment in Experimental Peritoneal Dialysis: Mohammad Zareie, Paolo Fabbrini, Liesbeth H.P. Hekking, Eelco D. Keuning, Piet M. ter Wee, Robert H.J. Beelen, and Jacob van den Born; J Am Soc Nephrol 17: 3447-3457. [Abstract] [Full Text] [PDF]

Disease of the Month:

Amyloidosis-Associated Kidney Disease: Laura M. Dember; J Am Soc Nephrol 17: 3458-3471. [Abstract] [Full Text] [PDF]

Clinical Nephrology:

Impact of Blood Pressure Control and Angiotensin-Converting Enzyme Inhibitor Therapy on New-Onset Microalbuminuria in Type 2 Diabetes: A Post Hoc Analysis of the BENEDICT Trial: Piero Ruggenenti, Annalisa Perna, Maria Ganeva, Bogdan Ene-Iordache, Giuseppe Remuzzi for the BENEDICT Study Group; J Am Soc Nephrol 17: 3472-3481. [Abstract] [Full Text] [PDF]

Effect of Various Diuretic Treatments on Rosiglitazone-Induced Fluid Retention: Janaka Karalliedde, Robin Buckingham, Margaret Starkie, Daniel Lorand, Murray Stewart, Giancarlo Viberti for the Rosiglitazone Fluid Retention Study Group; J Am Soc Nephrol 17: 3482-3490. [Abstract] [Full Text] [PDF]

Epidemiology and Outcomes:

African Ancestry, Socioeconomic Status, and Kidney Function in Elderly African Americans: A Genetic Admixture Analysis: Carmen A. Peralta, Elad Ziv, Ronit Katz, Alex Reiner, Esteban González Burchard, Linda Fried, Pui-Yan Kwok, Bruce Psaty, and Michael Shlipak; J Am Soc Nephrol 17: 3491-3496. [Abstract] [Full Text] [PDF]

Medical Costs of Untreated Anemia in Elderly Patients with Predialysis Chronic Kidney Disease: Patrick Lefebvre, Mei Sheng Duh, Sharon Buteau, Brahim Bookhart, and Samir H. Mody; J Am Soc Nephrol 17: 3497-3502. [Abstract] [Full Text] [PDF]

Clinical Dialysis:

Sleep Apnea in Patients on Conventional Thrice-Weekly Hemodialysis: Comparison with Matched Controls from the Sleep Heart Health Study: Mark L. Unruh, Mark H. Sanders, Susan Redline, Beth M. Piraino, Jason G. Umans, Terese C. Hammond, Imran Sharief, Naresh M. Punjabi, and Anne B. Newman; J Am Soc Nephrol 17: 3503-3509. [Abstract] [Full Text] [PDF]

International Differences in Dialysis Mortality Reflect Background General Population Atherosclerotic Cardiovascular Mortality: Maki Yoshino, Martin K. Kuhlmann, Peter Kotanko, Roger N. Greenwood, Ronald L. Pisoni, Friedrich K. Port, Kitty J. Jager, Peter Homel, Hans Augustijn, Frank T. de Charro, Frederic Collart, Ekrem Erek, Patrik Finne, Guillermo Garcia-Garcia, Carola Grönhagen-Riska, George A. Ioannidis, Frank Ivis, Torbjorn Leivestad, Hans Løkkegaard, Frantisek Lopot, Dong-Chan Jin, Reinhard Kramar, Toshiyuki Nakao, Mooppil Nandakumar, Sylvia Ramirez, Frank M. van der Sande, Staffan Schön, Keith Simpson, Rowan G. Walker, Wojciech Zaluska, and Nathan W. Levin; J Am Soc Nephrol 17: 3510-3519. [Abstract] [Full Text] [PDF]

Clinical Immunology and Pathology:

O-Glycosylation of Serum IgA1 Antibodies against Mucosal and Systemic Antigens in IgA Nephropathy: Alice C. Smith, Karen Molyneux, John Feehally, and Jonathan Barratt; J Am Soc Nephrol 17: 3520-3528. [Abstract] [Full Text] [PDF]

Differential Glycosylation of Polymeric and Monomeric IgA: A Possible Role in Glomerular Inflammation in IgA Nephropathy: Beatrijs D. Oortwijn, Anja Roos, Louise Royle, Daniëlle J. van Gijlswijk-Janssen, Maria C. Faber-Krol, Jan-Willem Eijgenraam, Raymond A. Dwek, Mohamed R. Daha, Pauline M. Rudd, and Cees van Kooten; J Am Soc Nephrol 17: 3529-3539. [Abstract] [Full Text] [PDF]

Erratum:

Correction: J Am Soc Nephrol 17: 3540. [Full Text] [PDF]

ASN News:

ASN News: J Am Soc Nephrol 17: A27-A28. [Full Text] [PDF]