THIS MONTH'S HIGHLIGHTS:

This Month’s Highlights

J Am Soc Nephrol 17: 315-316. [Full Text] [PDF]  

Nephrology beyond JASN:

Stem Cells of Aging Donors—Insufficient Capacity to Repair Causes Progression of Atherosclerosis in the Recipient: Molecular Evidence for Arterial Repair in Atherosclerosis. Proc Natl Acad Sci U S A 102: 16789-16794, 2005

R. Karra, S. Vemullapalli, C. Dong, E.E. Herderick, X. Song, K. Slosek, J.R. Nevins, M. West, P.J. Goldschmidt-Clermont, D. Seo, P. Muntner, A. Menke, Salvo K. De, F. Rabito, and V. Batuman

J Am Soc Nephrol 17: 317-322. [Full Text] [PDF]  

Editorials:

Endothelial Health and Diversity in the Kidney

Mark S. Segal, Chris Baylis, and Richard J. Johnson

J Am Soc Nephrol 17: 323-324. [Full Text] [PDF]  

Antiangiogenic Therapy in Diabetic Nephropathy

Roy Zent and Ambra Pozzi

J Am Soc Nephrol 17: 325-327. [Full Text] [PDF]  

Measuring T Cell Alloreactivity to Predict Kidney Transplant Outcomes: Are We There Yet?

John Iacomini and Mohamed H. Sayegh

J Am Soc Nephrol 17: 328-330. [Full Text] [PDF]  

Fast Track:

Urinary Albumin Excretion as a Predictor of the Development of Hypertension in the General Population

Auke H. Brantsma, Stephan J.L. Bakker, Dick de Zeeuw, Paul E. de Jong, Ronald T. Gansevoort for the PREVEND Study Group

J Am Soc Nephrol 17: 331-335. [Abstract] [Full Text] [PDF]  

Frontiers in Nephrology: Diabetic Nephropathy: Understanding Mechanism and Defining Risk:

Frontiers in Diabetic Nephropathy: Can We Predict Who Will Get Sick?

John R. Sedor

J Am Soc Nephrol 17: 336-338. [Full Text] [PDF]  

Enhancing the Predictive Value of Urinary Albumin for Diabetic Nephropathy

M. Luiza Caramori, Paola Fioretto, and Michael Mauer

J Am Soc Nephrol 17: 339-352. [Abstract] [Full Text] [PDF]  

Genetics of Diabetes and Its Complications

Stephen S. Rich

J Am Soc Nephrol 17: 353-360. [Full Text] [PDF]  

Diabetic Nephropathy: A Frontier for Personalized Medicine

Katalin Susztak and Erwin P. Böttinger

J Am Soc Nephrol 17: 361-367. [Abstract] [Full Text] [PDF]  

Leukocyte Recruitment and Vascular Injury in Diabetic Nephropathy

Elena Galkina and Klaus Ley

J Am Soc Nephrol 17: 368-377. [Abstract] [Full Text] [PDF]  

Review:

Unexpected Role of TRPC6 Channel in Familial Nephrotic Syndrome: Does It Have Clinical Implications?

Michelle P. Winn, Nikki Daskalakis, Robert F. Spurney, and John P. Middleton

J Am Soc Nephrol 17: 378-387. [Full Text] [PDF]  

Cell and Transport Physiology:

Nonspecific Cation Current Associated with Native Polycystin-2 in HEK-293 Cells

Bruna Pelucchi, Gianluca Aguiari, Angela Pignatelli, Elisa Manzati, Ralph Witzgall, Laura del Senno, and Ottorino Belluzzi

J Am Soc Nephrol 17: 388-397. [Abstract] [Full Text] [PDF]  

Intrinsic Gluconeogenesis Is Enhanced in Renal Proximal Tubules of Zucker Diabetic Fatty Rats

Assaad Eid, Sophie Bodin, Bernard Ferrier, Hélène Delage, Michelle Boghossian, Mireille Martin, Gabriel Baverel, and Agnès Conjard

J Am Soc Nephrol 17: 398-405. [Abstract] [Full Text] [PDF]  

Endothelin-Induced Increased Nitric Oxide Mediates Augmented Distal Nephron Acidification as a Result of Dietary Protein

Donald E. Wesson, Jan Simoni, and Sharma Prabhakar

J Am Soc Nephrol 17: 406-413. [Abstract] [Full Text] [PDF]  

Cell Biology:

Advanced Glycation End Products Inhibit Tubulogenesis and Migration of Kidney Epithelial Cells in an Ezrin-Dependent Manner

Marisa A Gallicchio, E. Anne McRobert, Anjali Tikoo, Mark E. Cooper, and Leon A. Bach

J Am Soc Nephrol 17: 414-421. [Abstract] [Full Text] [PDF]  

Genetics and Development:

Development of Gene Silencing Pyrrole-Imidazole Polyamide Targeting the TGF-1 Promoter for Treatment of Progressive Renal Diseases

Hiroyuki Matsuda, Noboru Fukuda, Takahiro Ueno, Yoshiko Tahira, Hirohito Ayame, Wen Zhang, Toshikazu Bando, Hiroshi Sugiyama, Satoshi Saito, Koichi Matsumoto, Hideo Mugishima, and Kazuo Serie

J Am Soc Nephrol 17: 422-432. [Abstract] [Full Text] [PDF]  

Hemodynamics and Vascular Regulation:

Antiatherogenic Effects of Angiotensin Receptor Antagonism in Mild Renal Dysfunction

Eisuke Suganuma, Yiqin Zuo, Nobuhiko Ayabe, Ji Ma, Vladimir R. Babaev, MacRae F. Linton, Sergio Fazio, Iekuni Ichikawa, Agnes B. Fogo, and Valentina Kon

J Am Soc Nephrol 17: 433-441. [Abstract] [Full Text] [PDF]  

Basic Immunology and Pathology:

IFN-Inducible Protein-10 Plays a Pivotal Role in Maintaining Slit-Diaphragm Function by Regulating Podocyte Cell-Cycle Balance

Gi Dong Han, Koichi Suzuki, Hiroko Koike, Kenji Suzuki, Hiroyuki Yoneyama, Shosaku Narumi, Fujio Shimizu, and Hiroshi Kawachi

J Am Soc Nephrol 17: 442-453. [Abstract] [Full Text] [PDF]  

Compartment-Specific Expression and Function of the Chemokine IP-10/CXCL10 in a Model of Renal Endothelial Microvascular Injury

Ulf Panzer, Oliver M. Steinmetz, Rüdiger R. Reinking, Tobias N. Meyer, Susanne Fehr, André Schneider, Gunther Zahner, Gunter Wolf, Udo Helmchen, Patrick Schaerli, Rolf A.K. Stahl, and Friedrich Thaiss

J Am Soc Nephrol 17: 454-464. [Abstract] [Full Text] [PDF]  

DNA Vaccination with CCL2 DNA Modified by the Addition of an Adjuvant Epitope Protects against "Nonimmune" Toxic Renal Injury

Guoping Zheng, Yiping Wang, Shi-Hua Xiang, Yuet-Ching Tay, Huiling Wu, Debbie Watson, Jason Coombes, Gopala K. Rangan, Stephen I. Alexander, and David C.H. Harris

J Am Soc Nephrol 17: 465-474. [Abstract] [Full Text] [PDF]  

Pathophysiology of Renal Disease and Progression:

Therapeutic Potential of Angiostatin in Diabetic Nephropathy

Sarah X. Zhang, Joshua J. Wang, Kangmo Lu, Robert Mott, Richard Longeras, and Jian-xing Ma

J Am Soc Nephrol 17: 475-486. [Abstract] [Full Text] [PDF]  

Clinical Nephrology:

Estimating Pediatric Glomerular Filtration Rates in the Era of Chronic Kidney Disease Staging

Andre Mattman, Shaun Eintracht, Thomas Mock, Geraldine Schick, David W. Seccombe, Robert Morrison Hurley, and Colin Thomas White

J Am Soc Nephrol 17: 487-496. [Abstract] [Full Text] [PDF]  

Human Genetics:

Renal Phenotypes Related to Hepatocyte Nuclear Factor-1 (TCF2) Mutations in a Pediatric Cohort

Tim Ulinski, Sandra Lescure, Sandrine Beaufils, Vincent Guigonis, Stéphane Decramer, Denis Morin, Séverine Clauin, Georges Deschênes, François Bouissou, Albert Bensman, and Christine Bellanné-Chantelot

J Am Soc Nephrol 17: 497-503. [Abstract] [Full Text] [PDF]  

Genetic Variation of the Renin-Angiotensin System and Chronic Kidney Disease Progression in Black Individuals in the Atherosclerosis Risk in Communities Study

Charles Chia-chuen Hsu, Molly S. Bray, W.H.Linda Kao, James S. Pankow, Eric Boerwinkle, and Josef Coresh

J Am Soc Nephrol 17: 504-512. [Abstract] [Full Text] [PDF]  

Epidemiology and Outcomes:

Changing Relationship of Blood Pressure with Mortality over Time among Hemodialysis Patients

Christine A. Stidley, William C. Hunt, Francesca Tentori, Darren Schmidt, Mark Rohrscheib, Susan Paine, Edward J. Bedrick, Klemens B. Meyer, H. Keith Johnson, Philip G. Zager for the Medical Directors of Dialysis Clinic Inc.

J Am Soc Nephrol 17: 513-520. [Abstract] [Full Text] [PDF]  

Cross-Sectional Association of Kidney Function with Valvular and Annular Calcification: The Framingham Heart Study

Caroline S. Fox, Martin G. Larson, Ramachandran S. Vasan, Chao-Yu Guo, Helen Parise, Daniel Levy, Eric P. Leip, Christopher J. O’Donnell, Ralph B. D’Agostino, Sr., and Emelia J. Benjamin

J Am Soc Nephrol 17: 521-527. [Abstract] [Full Text] [PDF]  

Apolipoprotein A-IV Predicts Progression of Chronic Kidney Disease: The Mild to Moderate Kidney Disease Study

Eva Boes, Danilo Fliser, Eberhard Ritz, Paul König, Karl Lhotta, Johannes F.E. Mann, Gerhard A. Müller, Ulrich Neyer, Werner Riegel, Peter Riegler, Florian Kronenberg for the MMKD Study Group

J Am Soc Nephrol 17: 528-536. [Abstract] [Full Text] [PDF]  

Endothelial Dysfunction Contributes to Renal Function–Associated Cardiovascular Mortality in a Population with Mild Renal Insufficiency: The Hoorn Study

Frank Stam, Coen van Guldener, Annemarie Becker, Jacqueline M. Dekker, Robert J. Heine, Lex M. Bouter, and Coen D.A. Stehouwer

J Am Soc Nephrol 17: 537-545. [Abstract] [Full Text] [PDF]  

Clinical Dialysis:

Serum -2 Microglobulin Levels Predict Mortality in Dialysis Patients: Results of the HEMO Study

Alfred K. Cheung, Michael V. Rocco, Guofen Yan, John K. Leypoldt, Nathan W. Levin, Tom Greene, Lawrence Agodoa, James Bailey, Gerald J. Beck, William Clark, Andrew S. Levey, Daniel B. Ornt, Gerald Schulman, Steven Schwab, Brendan Teehan, Garabed Eknoyan for HEMO Study Group

J Am Soc Nephrol 17: 546-555. [Abstract] [Full Text] [PDF]  

Clinical Immunology and Pathology:

How Many Glomerular Profiles Must Be Measured to Obtain Reliable Estimates of Mean Glomerular Areas in Human Renal Biopsies?

Wendy E. Hoy, Terence Samuel, Michael D. Hughson, Jennifer L. Nicol, and John F. Bertram

J Am Soc Nephrol 17: 556-563. [Abstract] [Full Text] [PDF]  

Clinical Transplantation:

Panel of Reactive T Cells as a Measurement of Primed Cellular Alloimmunity in Kidney Transplant Candidates

Emilio D. Poggio, Michael Clemente, Donald E. Hricik, and Peter S. Heeger

J Am Soc Nephrol 17: 564-572. [Abstract] [Full Text] [PDF]  

Identification of Dialysis Patients with Panel-Reactive Memory T Cells before Kidney Transplantation Using an Allogeneic Cell Bank

Holger Andree, Peter Nickel, Christin Nasiadko, Markus H. Hammer, Constanze Schönemann, Axel Pruss, Hans-Dieter Volk, and Petra Reinke

J Am Soc Nephrol 17: 573-580. [Abstract] [Full Text] [PDF]  

Sirolimus Therapy after Early Cyclosporine Withdrawal Reduces the Risk for Cancer in Adult Renal Transplantation

Josep M. Campistol, Josette Eris, Rainer Oberbauer, Peter Friend, Brian Hutchison, José M. Morales, Kerstin Claesson, Giovanni Stallone, Graeme Russ, Lionel Rostaing, Henri Kreis, James T. Burke, Yves Brault, Joseph A. Scarola, John F. Neylan for the Rapamune Maintenance Regimen Study Group

J Am Soc Nephrol 17: 581-589. [Abstract] [Full Text] [PDF]  

Announcement:

Announcements

J Am Soc Nephrol 17: 590. [Full Text] [PDF]  

Errata:

Errata

J Am Soc Nephrol 17: 591. [Full Text] [PDF]  

Errata

J Am Soc Nephrol 17: 591. [Full Text] [PDF]  

Errata

J Am Soc Nephrol 17: 591. [Full Text] [PDF]  

ASN News:

ASN News

J Am Soc Nephrol 17: A23-A25. [Full Text] [PDF]  

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