THIS MONTH'S HIGHLIGHTS:

This Month’s Highlights

J Am Soc Nephrol 17: 593-594. [Full Text] [PDF]  

Nephrology beyond JASN:

Radiocontrast-Induced Acute Renal Failure—Impact beyond the Acute Phase: Contrast-Induced Nephropathy after Percutaneous Coronary Interventions in Relation to Chronic Kidney Disease and Hemodynamic Variables. Am J Cardiol 95: 13–19, 2005

Dangas G., Iakovou I., Nikolsky E., Aymong E.D., Mintz G.S., Kipshidze N.N., Lansky A.J., Moussa I., Stone G.W., Moses J.W., Leon M.B., Mehran R., De Tomaso A.W., Nyholm S.V., Palmeri K.J., Ishizuka K.J., Ludington W.B., Mitchel K., and Weissman I.L.

J Am Soc Nephrol 17: 595-599. [Full Text] [PDF]  

Editorials:

World Kidney Day: An Idea Whose Time Has Come

Allan J. Collins, William G. Couser, John H. Dirks, Joel D. Kopple, Thomas Reiser, Miguel C. Riella, Sheila Robinson, Sudhir V. Shah, and Anne Wilson

J Am Soc Nephrol 17: 600-601. [Full Text] [PDF]  

How Much VEGF Do You Need?

Peter W. Mathieson

J Am Soc Nephrol 17: 602-603. [Full Text] [PDF]  

Immune Modulation of Acute Kidney Injury

Hamid Rabb

J Am Soc Nephrol 17: 604-606. [Full Text] [PDF]  

Review:

Cellular Effects of Guanylin and Uroguanylin

Aleksandra Sindic and Eberhard Schlatter

J Am Soc Nephrol 17: 607-616. [Abstract] [Full Text] [PDF]  

Cell and Transport Physiology:

Acid-Base Status Determines the Renal Expression of Ca²⁺ and Mg²⁺ Transport Proteins

Tom Nijenhuis, Kirsten Y. Renkema, Joost G.J. Hoenderop, and René J.M. Bindels

J Am Soc Nephrol 17: 617-626. [Abstract] [Full Text] [PDF]  

Cell Biology:

CD40L Proinflammatory and Profibrotic Effects on Proximal Tubular Epithelial Cells: Role of NF-B and Lyn

Paola Pontrelli, Michele Ursi, Elena Ranieri, Carmen Capobianco, Francesco P. Schena, Loreto Gesualdo, and Giuseppe Grandaliano

J Am Soc Nephrol 17: 627-636. [Abstract] [Full Text] [PDF]  

Polycystin-1 Induces Resistance to Apoptosis through the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway

Manila Boca, Gianfranco Distefano, Feng Qian, Anil K. Bhunia, Gregory G. Germino, and Alessandra Boletta

J Am Soc Nephrol 17: 637-647. [Abstract] [Full Text] [PDF] [Data Supplements]  

Genetics and Development:

Podocyte Cell–Specific Expression of Doxycycline Inducible Cre Recombinase in Mice

Juuso Juhila, Ramon Roozendaal, Markus Lassila, Sjef J. Verbeek, and Harry Holthofer

J Am Soc Nephrol 17: 648-654. [Abstract] [Full Text] [PDF] [Data Supplement]  

Hemodynamics and Vascular Regulation:

Acute Blood Pressure Effects and Chronic Hypotensive Action of Calcimimetics in Uremic Rats

Tobias Odenwald, Kumiko Nakagawa, Charlotte Hadtstein, Frank Roesch, Peter Gohlke, Eberhard Ritz, Franz Schaefer, and Claus Peter Schmitt

J Am Soc Nephrol 17: 655-662. [Abstract] [Full Text] [PDF]  

Prevention of Lithotripsy-Induced Renal Injury by Pretreating Kidneys with Low-Energy Shock Waves

Lynn R. Willis, Andrew P. Evan, Bret A. Connors, Rajash K. Handa, Philip M. Blomgren, and James E. Lingeman

J Am Soc Nephrol 17: 663-673. [Abstract] [Full Text] [PDF]  

Basic Immunology and Pathology:

N-Acetyl-Seryl-Aspartyl-Lysyl-Proline Ameliorates the Progression of Renal Dysfunction and Fibrosis in WKY Rats with Established Anti–Glomerular Basement Membrane Nephritis

Mitsugu Omata, Hajime Taniguchi, Daisuke Koya, Keizo Kanasaki, Rumiko Sho, Yoshimi Kato, Ryoji Kojima, Masakazu Haneda, and Norio Inomata

J Am Soc Nephrol 17: 674-685. [Abstract] [Full Text] [PDF]  

Accumulation of Immune Complexes in Glomerular Disease Is Independent of Locally Synthesized C3

Neil S. Sheerin, Katsushige Abe, Paul Risley, and Steven H. Sacks

J Am Soc Nephrol 17: 686-696. [Abstract] [Full Text] [PDF]  

Foxp3-Transduced Polyclonal Regulatory T Cells Protect against Chronic Renal Injury from Adriamycin

Yuan Min Wang, Geoff Yu Zhang, Yiping Wang, Min Hu, Huiling Wu, Debbie Watson, Shohei Hori, Ian E. Alexander, David C.H. Harris, and Stephen I. Alexander

J Am Soc Nephrol 17: 697-706. [Abstract] [Full Text] [PDF]  

Treatment with an Inhibitory Monoclonal Antibody to Mouse Factor B Protects Mice from Induction of Apoptosis and Renal Ischemia/Reperfusion Injury

Joshua M. Thurman, Pamela A. Royer, Danica Ljubanovic, Belda Dursun, Amanda M. Lenderink, Charles L. Edelstein, and V. Michael Holers

J Am Soc Nephrol 17: 707-715. [Abstract] [Full Text] [PDF]  

Role of CXC Chemokine Receptor 3 Pathway in Renal Ischemic Injury

Paolo Fiorina, Mohammed Javeed Ansari, Mollie Jurewicz, Mark Barry, Vincent Ricchiuti, Rex Neal Smith, Susan Shea, Terry K. Means, Hugh Auchincloss, Jr., Andrew D. Luster, Mohamed H. Sayegh, and Reza Abdi

J Am Soc Nephrol 17: 716-723. [Abstract] [Full Text] [PDF]  

Pathophysiology of Renal Disease and Progression:

Vascular Endothelial Growth Factor A Signaling in the Podocyte-Endothelial Compartment Is Required for Mesangial Cell Migration and Survival

Vera Eremina, Shiying Cui, Hanspeter Gerber, Napoleone Ferrara, Jody Haigh, Andras Nagy, Masatsugu Ema, Janet Rossant, Serge Jothy, Jeffrey H. Miner, and Susan E. Quaggin

J Am Soc Nephrol 17: 724-735. [Abstract] [Full Text] [PDF]  

Uncoupling of Vascular Endothelial Growth Factor with Nitric Oxide as a Mechanism for Diabetic Vasculopathy

Takahiko Nakagawa, Waichi Sato, Yuri Y. Sautin, Olena Glushakova, Byron Croker, Mark A. Atkinson, C. Craig Tisher, and Richard J. Johnson

J Am Soc Nephrol 17: 736-745. [Abstract] [Full Text] [PDF]  

CD44 Disruption Prevents Degeneration of the Capillary Network in Obstructive Nephropathy via Reduction of TGF-1–Induced Apoptosis

Kasper M.A. Rouschop, Nike Claessen, Steven T. Pals, Jan J. Weening, and Sandrine Florquin

J Am Soc Nephrol 17: 746-753. [Abstract] [Full Text] [PDF]  

Fluvastatin Ameliorates Podocyte Injury in Proteinuric Rats via Modulation of Excessive Rho Signaling

Shigeru Shibata, Miki Nagase, and Toshiro Fujita

J Am Soc Nephrol 17: 754-764. [Abstract] [Full Text] [PDF]  

A Pathophysiologic Role for T Lymphocytes in Murine Acute Cisplatin Nephrotoxicity

Manchang Liu, Chu-Chun Chien, Melissa Burne-Taney, Roshni R. Molls, Lorraine C. Racusen, Robert B. Colvin, and Hamid Rabb

J Am Soc Nephrol 17: 765-774. [Abstract] [Full Text] [PDF]  

Bone Marrow–Derived Cells Do Not Contribute Significantly to Collagen I Synthesis in a Murine Model of Renal Fibrosis

Candice Roufosse, George Bou-Gharios, Evangelia Prodromidi, Catherine Alexakis, Rosemary Jeffery, Sarah Khan, William R. Otto, Julia Alter, Richard Poulsom, and H. Terence Cook

J Am Soc Nephrol 17: 775-782. [Abstract] [Full Text] [PDF]  

Addition of the Antioxidant Probucol to Angiotensin II Type I Receptor Antagonist Arrests Progressive Mesangioproliferative Glomerulonephritis in the Rat

Shuji Kondo, Maki Shimizu, Maki Urushihara, Koichiro Tsuchiya, Masanori Yoshizumi, Toshiaki Tamaki, Akira Nishiyama, Hiroshi Kawachi, Fujio Shimizu, Mark T. Quinn, David J. Lambeth, and Shoji Kagami

J Am Soc Nephrol 17: 783-794. [Abstract] [Full Text] [PDF]  

Basic Mineral Metabolism and Bone Disease:

Calcimimetic R-568 Decreases Extraosseous Calcifications in Uremic Rats Treated with Calcitriol

Ignacio Lopez, Escolastico Aguilera-Tejero, Francisco J. Mendoza, Yolanda Almaden, Jose Perez, David Martin, and Mariano Rodriguez

J Am Soc Nephrol 17: 795-804. [Abstract] [Full Text] [PDF]  

Basic Transplantation:

Heat Shock–Induced Protection of Renal Proximal Tubular Epithelial Cells from Cold Storage and Rewarming Injury

Declan A. Healy, Padraig J. Daly, Neil G. Docherty, Madeline Murphy, John M. Fitzpatrick, and R. William G. Watson

J Am Soc Nephrol 17: 805-812. [Abstract] [Full Text] [PDF]  

Disease of the Month:

Thin Basement Membrane Nephropathy

Karl Tryggvason and Jaakko Patrakka

J Am Soc Nephrol 17: 813-822. [Full Text] [PDF]  

Human Genetics:

Functional Polymorphisms in the Vascular Endothelial Growth Factor Gene Are Associated with Development of End-Stage Renal Disease in Males

Kent Doi, Eisei Noiri, Akihide Nakao, Toshiro Fujita, Shuzo Kobayashi, and Katsushi Tokunaga

J Am Soc Nephrol 17: 823-830. [Abstract] [Full Text] [PDF]  

A Genome-Wide DNA Microsatellite Association Screen to Identify Chromosomal Regions Harboring Candidate Genes in Diabetic Nephropathy

Amy Jayne McKnight, A. Peter Maxwell, Stephen Sawcer, Alastair Compston, Efrosini Setakis, Chris C. Patterson, Hugh R. Brady, and David A. Savage

J Am Soc Nephrol 17: 831-836. [Abstract] [Full Text] [PDF]  

Epidemiology and Outcomes:

Adverse Perinatal Outcome and Later Kidney Biopsy in the Mother

Bjørn Egil Vikse, Lorentz M. Irgens, Leif Bostad, and Bjarne M. Iversen

J Am Soc Nephrol 17: 837-845. [Abstract] [Full Text] [PDF]  

Mortality Risk Stratification in Chronic Kidney Disease: One Size for All Ages?

Ann M. O’Hare, Daniel Bertenthal, Kenneth E. Covinsky, C. Seth Landefeld, Saunak Sen, Kala Mehta, Michael A. Steinman, Ann Borzecki, and Louise C. Walter

J Am Soc Nephrol 17: 846-853. [Abstract] [Full Text] [PDF]  

Comparison of Methods for Determining Renal Function Decline in Early Autosomal Dominant Polycystic Kidney Disease: The Consortium of Radiologic Imaging Studies of Polycystic Kidney Disease Cohort

Andrew D. Rule, Vicente E. Torres, Arlene B. Chapman, Jared J. Grantham, Lisa M. Guay-Woodford, Kyongtae T. Bae, Saulo Klahr, William M. Bennett, Catherine M. Meyers, Paul A. Thompson, J. Philip Miller CRISP Consortium

J Am Soc Nephrol 17: 854-862. [Abstract] [Full Text] [PDF]  

IL-6 Haplotypes, Inflammation, and Risk for Cardiovascular Disease in a Multiethnic Dialysis Cohort

Yongmei Liu, Yvette Berthier-Schaad, Margaret D. Fallin, Nancy E. Fink, Russell P. Tracy, Michael J. Klag, Michael W. Smith, and Josef Coresh

J Am Soc Nephrol 17: 863-870. [Abstract] [Full Text] [PDF]  

Clinical Transplantation:

Explaining Variability in Mycophenolic Acid Exposure to Optimize Mycophenolate Mofetil Dosing: A Population Pharmacokinetic Meta-Analysis of Mycophenolic Acid in Renal Transplant Recipients

Reinier M. van Hest, Ron A.A. Mathot, Mark D. Pescovitz, Robert Gordon, Richard D. Mamelok, and Teun van Gelder

J Am Soc Nephrol 17: 871-880. [Abstract] [Full Text] [PDF]  

Molecular Comparison of Calcineurin Inhibitor–Induced Fibrogenic Responses in Protocol Renal Transplant Biopsies

Marian C. Roos-van Groningen, Eduard M. Scholten, Patrick M. Lelieveld, Ajda T. Rowshani, Hans J. Baelde, Ingeborg M. Bajema, Sandrine Florquin, Frederike J. Bemelman, Emile de Heer, Johan W. de Fijter, Jan A. Bruijn, and Michael Eikmans

J Am Soc Nephrol 17: 881-888. [Abstract] [Full Text] [PDF]  

Angiotensin-Converting Enzyme Inhibitor or Angiotensin II Type 1 Receptor Antagonist Therapy Is Associated with Prolonged Patient and Graft Survival after Renal Transplantation

Georg Heinze, Christa Mitterbauer, Heinz Regele, Reinhard Kramar, Wolfgang C. Winkelmayer, Gary C. Curhan, and Rainer Oberbauer

J Am Soc Nephrol 17: 889-899. [Abstract] [Full Text] [PDF]  

Acute Myocardial Infarction and Kidney Transplantation

Bertram L. Kasiske, J. Ross Maclean, and Jon J. Snyder

J Am Soc Nephrol 17: 900-907. [Abstract] [Full Text] [PDF]  

Announcements:

Announcements

J Am Soc Nephrol 17: 908. [Full Text] [PDF]  

ASN News:

ASN News

J Am Soc Nephrol 17: A23-A24. [Full Text] [PDF]  

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