TABLE OF CONTENTS: Volume 20, Issue 10, October 2009

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UP FRONT MATTERS

Editorials
Occasional Observation
Clinical Commentary
Brief Reviews

This Month's Highlights

BRIEF COMMUNICATION

BASIC RESEARCH

CLINICAL EPIDEMIOLOGY

CLINICAL RESEARCH

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This Month's Highlights

This Month's Highlights
J Am Soc Nephrol 20: A12. [Full Text] [PDF]

UP FRONT MATTERS

Editorials

Insight versus Quagmire with Compound HIV Transgenics
Leslie A. Bruggeman J Am Soc Nephrol 20: 2085-2086. [Full Text] [PDF]

Surprising Results following Conditional Podocyte Inactivation
Martin R. Pollak J Am Soc Nephrol 20: 2086-2088. [Full Text] [PDF]

More Evidence that Cystatin C Predicts Mortality Better than Creatinine
Peter P. Reese and Harold I. Feldman J Am Soc Nephrol 20: 2088-2090. [Full Text] [PDF]

Warfarin and Stroke Outcomes in Hemodialysis Patients with Atrial Fibrillation
Simonetta Genovesi and Antonio Santoro J Am Soc Nephrol 20: 2090-2092. [Full Text] [PDF]

Occasional Observation

ESRD as a Window into America's Cost Crisis in Health Care
Felix Knauf and Peter S. Aronson J Am Soc Nephrol 20: 2093-2097. [Full Text] [PDF]

Clinical Commentary

Over-the-Counter Analgesic Use
Marc E. De Broe and Monique M. Elseviers J Am Soc Nephrol 20: 2098-2103. [Abstract] [Full Text] [PDF]

Brief Reviews

Planar Cell Polarity and the Kidney
Helen McNeill J Am Soc Nephrol 20: 2104-2111. [Abstract] [Full Text] [PDF]

Is There Such a Thing as a Renal Stem Cell?
Melissa H. Little and John F. Bertram J Am Soc Nephrol 20: 2112-2117. [Abstract] [Full Text] [PDF]

BRIEF COMMUNICATION

Modification of Collagen IV by Glucose or Methylglyoxal Alters Distinct Mesangial Cell Functions
Ambra Pozzi, Roy Zent, Sergei Chetyrkin, Corina Borza, Nada Bulus, Peale Chuang, Dong Chen, Billy Hudson, and Paul Voziyan J Am Soc Nephrol 20: 2119-2125. [Abstract] [Full Text] [PDF] [Supplemental Data]

BASIC RESEARCH

TβRI Independently Activates Smad- and CD2AP-Dependent Pathways in Podocytes
Sandhya Xavier, Thiruvur Niranjan, Stefanie Krick, Taoran Zhang, Wenjun Ju, Andrey S. Shaw, Mario Schiffer, and Erwin P. Böttinger J Am Soc Nephrol 20: 2127-2137. [Abstract] [Full Text] [PDF]

Reduction of Stat3 Activity Attenuates HIV-Induced Kidney Injury
Xiaobei Feng, Ting-Chi Lu, Peter Y. Chuang, Wei Fang, Krishna Ratnam, Huabao Xiong, Xinshou Ouyang, Yuhong Shen, David E. Levy, Deborah Hyink, Mary Klotman, Vivette D'Agati, Ravi Iyengar, Paul E. Klotman, and John C. He J Am Soc Nephrol 20: 2138-2146. [Abstract] [Full Text] [PDF] [Supplemental Data]

Renal Primary Cilia Lengthen after Acute Tubular Necrosis
Elizabeth Verghese, Sharon D. Ricardo, Raphael Weidenfeld, Junli Zhuang, Prudence A. Hill, Robyn G. Langham, and James A. Deane J Am Soc Nephrol 20: 2147-2153. [Abstract] [Full Text] [PDF]

Hypotonicity-Induced Renin Exocytosis from Juxtaglomerular Cells Requires Aquaporin-1 and Cyclooxygenase-2
Ulla G. Friis, Kirsten Madsen, Per Svenningsen, Pernille B.L. Hansen, Ambika Gulaveerasingam, Finn Jørgensen, Christian Aalkjær, Ole Skøtt, and Boye L. Jensen J Am Soc Nephrol 20: 2154-2161. [Abstract] [Full Text] [PDF]

The Orphan Nuclear Receptor SHP Attenuates Renal Fibrosis
Gwon-Soo Jung, Mi-Kyung Kim, Mi Sun Choe, Kyeong-Min Lee, Hye-Soon Kim, Young Joo Park, Hueng-Sik Choi, Ki-Up Lee, Keun-Gyu Park, and In-Kyu Lee J Am Soc Nephrol 20: 2162-2170. [Abstract] [Full Text] [PDF] [Supplemental Data]

MMP9 Limits Apoptosis and Stimulates Branching Morphogenesis During Kidney Development
Catherine Arnould, Martine Lelièvre-Pégorier, Pierre Ronco, and Brigitte Lelongt J Am Soc Nephrol 20: 2171-2180. [Abstract] [Full Text] [PDF]

Podocin Inactivation in Mature Kidneys Causes Focal Segmental Glomerulosclerosis and Nephrotic Syndrome
Géraldine Mollet, Julien Ratelade, Olivia Boyer, Andrea Onetti Muda, Ludivine Morisset, Tiphaine Aguirre Lavin, David Kitzis, Margaret J. Dallman, Laurence Bugeon, Norbert Hubner, Marie-Claire Gubler, Corinne Antignac, and Ernie L. Esquivel J Am Soc Nephrol 20: 2181-2189. [Abstract] [Full Text] [PDF] [Supplemental Data]

Biased Agonist Pharmacochaperones of the AVP V2 Receptor May Treat Congenital Nephrogenic Diabetes Insipidus
Frédéric Jean-Alphonse, Sanja Perkovska, Marie-Céline Frantz, Thierry Durroux, Catherine Méjean, Denis Morin, Stéphanie Loison, Dominique Bonnet, Marcel Hibert, Bernard Mouillac, and Christiane Mendre J Am Soc Nephrol 20: 2190-2203. [Abstract] [Full Text] [PDF] [Supplemental Data]

CLINICAL EPIDEMIOLOGY

Cost-Effectiveness of Aliskiren in Type 2 Diabetes, Hypertension, and Albuminuria
Thomas E. Delea, Oleg Sofrygin, James L. Palmer, Helen Lau, Veronica C. Munk, Jennifer Sung, Alan Charney, Hans-Henrik Parving, and Sean D. Sullivan J Am Soc Nephrol 20: 2205-2213. [Abstract] [Full Text] [PDF]

Method of Glomerular Filtration Rate Estimation Affects Prediction of Mortality Risk
Brad C. Astor, Andrew S. Levey, Lesley A. Stevens, Frederick Van Lente, Elizabeth Selvin, and Josef Coresh J Am Soc Nephrol 20: 2214-2222. [Abstract] [Full Text] [PDF]

Warfarin Use Associates with Increased Risk for Stroke in Hemodialysis Patients with Atrial Fibrillation
Kevin E. Chan, J. Michael Lazarus, Ravi Thadhani, and Raymond M. Hakim J Am Soc Nephrol 20: 2223-2233. [Abstract] [Full Text] [PDF] [Supplemental Data][Press Release]

CLINICAL RESEARCH

The Soluble VEGF Receptor sFlt1 Contributes to Endothelial Dysfunction in CKD
Giovana S. Di Marco, Stefan Reuter, Uta Hillebrand, Susanne Amler, Maximilian König, Etienne Larger, Hans Oberleithner, Eva Brand, Hermann Pavenstädt, and Marcus Brand J Am Soc Nephrol 20: 2235-2245. [Abstract] [Full Text] [PDF] [Supplemental Data]

Endogenous Bradykinin Contributes to Increased Plasminogen Activator Inhibitor 1 Antigen following Hemodialysis
Annis M. Marney, Ji Ma, James M. Luther, T. Alp Ikizler, and Nancy J. Brown J Am Soc Nephrol 20: 2246-2252. [Abstract] [Full Text] [PDF] [Supplemental Data]

DASH-Style Diet Associates with Reduced Risk for Kidney Stones
Eric N. Taylor, Teresa T. Fung, and Gary C. Curhan J Am Soc Nephrol 20: 2253-2259. [Abstract] [Full Text] [PDF] [Press Release]

Combination of Peritubular C4d and Transplant Glomerulopathy Predicts Late Renal Allograft Failure
Niamh Kieran, Xiaotong Wang, James Perkins, Connie Davis, Elizabeth Kendrick, Ramaswamy Bakthavatsalam, Nancy Dunbar, Paul Warner, Karen Nelson, Kelly D. Smith, Roberto F. Nicosia, Charles E. Alpers, Nicolae Leca, and Jolanta Kowalewska J Am Soc Nephrol 20: 2260-2268. [Abstract] [Full Text] [PDF]

ESRD Impairs Nonrenal Clearance of Fexofenadine but not Midazolam
Thomas D. Nolin, Reginald F. Frye, Phuong Le, Hooman Sadr, Judith Naud, Francois A. Leblond, Vincent Pichette, and Jonathan Himmelfarb J Am Soc Nephrol 20: 2269-2276. [Abstract] [Full Text] [PDF]