TABLE OF CONTENTS: Volume 20, Issue 4, April 2009

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UP FRONT MATTERS

Editorials
Clinical Commentary
Brief Reviews

This Month's Highlights

BASIC RESEARCH

CLINICAL EPIDEMIOLOGY

CLINICAL RESEARCH

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This Month's Highlights

This Month's Highlights
J Am Soc Nephrol 20: A12. [Full Text] [PDF]

UP FRONT MATTERS

Editorials

The Patient-Centered Medical Home and Nephrology
Thomas D. DuBose, Jr., Mary Tessie Behrens, Arnold Berns, Connie Davis, Stanley Goldfarb, Thomas Hostetter, Paul Klotman, Stuart Linas, Susan Owens, Lynda Szczech, and Jonathan Himmelfarb J Am Soc Nephrol 20: 681-682. [Full Text] [PDF]

Initial Insight on the Determinants of Podocyte Polarity
Lawrence B. Holzman and Puneet Garg J Am Soc Nephrol 20: 683-685. [Full Text] [PDF]

Interfacing Kidney Stroma with Dendritic Cells
Zae Kim and Peter J. Nelson J Am Soc Nephrol 20: 685-686. [Full Text] [PDF]

Are We Ready to Screen the General Population for Microalbuminuria?
Linda Fried J Am Soc Nephrol 20: 686-688. [Full Text] [PDF]

Drug Dosing for Renoprotection: Maybe It's Time for a Drug Efficacy-Safety Score?
Dick de Zeeuw and Hiddo Lambers-Heerspink J Am Soc Nephrol 20: 688-689. [Full Text] [PDF]

Treatment of Membranous Lupus Nephritis: Where Are We Now?
Laurence H. Beck, Jr. and David J. Salant J Am Soc Nephrol 20: 690-691. [Full Text] [PDF]

Clinical Commentary

Bicarbonate Therapy in Severe Metabolic Acidosis
Sandra Sabatini and Neil A. Kurtzman J Am Soc Nephrol 20: 692-695. [Abstract] [Full Text] [PDF]

Brief Reviews

Nephritogenic Potential of Anti-DNA Antibodies against Necrotic Nucleosomes
Elin Synnøve Mortensen and Ole Petter Rekvig J Am Soc Nephrol 20: 696-704. [Abstract] [Full Text] [PDF]

Dilemmas in the Management of Atrial Fibrillation in Chronic Kidney Disease
Holger Reinecke, Eva Brand, Rolf Mesters, Wolf-Rüdiger Schäbitz, Marc Fisher, Hermann Pavenstädt, and Günter Breithardt J Am Soc Nephrol 20: 705-711. [Abstract] [Full Text] [PDF]

BASIC RESEARCH

Xenon Preconditioning Protects against Renal Ischemic-Reperfusion Injury via HIF-1 ${alpha}$ Activation
Daqing Ma, Ta Lim, Jing Xu, Haidy Tang, Yanjie Wan, Hailin Zhao, Mahmuda Hossain, Patrick H. Maxwell, and Mervyn Maze J Am Soc Nephrol 20: 713-720. [Abstract] [Full Text] [PDF]

Thiazolidinedione-Induced Fluid Retention Is Independent of Collecting Duct ${alpha}$ ENaC Activity
Volker Vallon, Edith Hummler, Timo Rieg, Oleh Pochynyuk, Vladislav Bugaj, Jana Schroth, Georges Dechenes, Bernard Rossier, Robyn Cunard, and James Stockand J Am Soc Nephrol 20: 721-729. [Abstract] [Full Text] [PDF]

Expression, Localization, and Function of the Thioredoxin System in Diabetic Nephropathy
Andrew Advani, Richard E. Gilbert, Kerri Thai, Renae M. Gow, Robyn G. Langham, Alison J. Cox, Kim A. Connelly, Yuan Zhang, Andrew M. Herzenberg, Per Knud Christensen, Carol A. Pollock, Weier Qi, Sih Min Tan, Hans-Henrik Parving, and Darren J. Kelly J Am Soc Nephrol 20: 730-741. [Abstract] [Full Text] [PDF] [Supplemental Data]

RAGE-Induced Cytosolic ROS Promote Mitochondrial Superoxide Generation in Diabetes
Melinda T. Coughlan, David R. Thorburn, Sally A. Penfold, Adrienne Laskowski, Brooke E. Harcourt, Karly C. Sourris, Adeline L.Y. Tan, Kei Fukami, Vicki Thallas-Bonke, Peter P. Nawroth, Michael Brownlee, Angelika Bierhaus, Mark E. Cooper, and Josephine M. Forbes J Am Soc Nephrol 20: 742-752. [Abstract] [Full Text] [PDF] [Supplemental Data]

A Mouse Model for Meckel Syndrome Type 3
Susan A. Cook, Gayle B. Collin, Roderick T. Bronson, Jürgen K. Naggert, Dong P. Liu, Ellen C. Akeson, and Muriel T. Davisson J Am Soc Nephrol 20: 753-764. [Abstract] [Full Text] [PDF]

Wnt/β-Catenin Signaling Promotes Renal Interstitial Fibrosis
Weichun He, Chunsun Dai, Yingjian Li, Gang Zeng, Satdarshan P. Monga, and Youhua Liu J Am Soc Nephrol 20: 765-776. [Abstract] [Full Text] [PDF] [Supplemental Data]

Placental Insufficiency Associated with Loss of Cited1 Causes Renal Medullary Dysplasia
Duncan B. Sparrow, Scott C. Boyle, Rebecca S. Sams, Bogdan Mazuruk, Li Zhang, Gilbert W. Moeckel, Sally L. Dunwoodie, and Mark P. de Caestecker J Am Soc Nephrol 20: 777-786. [Abstract] [Full Text] [PDF]

MMP9 and SCF Protect from Apoptosis in Acute Kidney Injury
Soraya Bengatta, Catherine Arnould, Emmanuel Letavernier, Matthieu Monge, Hélène Martinan de Préneuf, Zena Werb, Pierre Ronco, and Brigitte Lelongt J Am Soc Nephrol 20: 787-797. [Abstract] [Full Text] [PDF]

Loss of Podocyte aPKC ${lambda}$ / ${iota}$ Causes Polarity Defects and Nephrotic Syndrome
Tobias B. Huber, Björn Hartleben, Kirstin Winkelmann, Lisa Schneider, Jan U. Becker, Michael Leitges, Gerd Walz, Hermann Haller, and Mario Schiffer J Am Soc Nephrol 20: 798-806. [Abstract] [Full Text] [PDF] [Supplemental Data]

C/EBP-β Modulates Transcription of Tubulointerstitial Nephritis Antigen in Obstructive Uropathy
Ping Xie, Lin Sun, Baibasawata Nayak, Yoshisuke Haruna, Fu-you Liu, Naoki Kashihara, and Yashpal S. Kanwar J Am Soc Nephrol 20: 807-819. [Abstract] [Full Text] [PDF]

Regulatory Allospecific T Cell Clones Abrogate Chronic Allograft Rejection
Ana Maria Waaga-Gasser, Martin R. Grimm, Jens Lutz, Volkmar Lange, Susanne M. Lenhard, Beatriz Aviles, Joana E. Kist-van Holthe, Tatiana Lebedeva, Dimitry Samsonov, Detlef Meyer, Wayne W. Hancock, Uwe Heemann, Martin Gasser, and Anil Chandraker J Am Soc Nephrol 20: 820-830. [Abstract] [Full Text] [PDF]

Kidney-Derived Stromal Cells Modulate Dendritic and T Cell Responses
Yanfei Huang, Peter Johnston, Borui Zhang, Asif Zakari, Tayseer Chowdhry, Rachel Ruckdeschel Smith, Eduardo Marbán, Hamid Rabb, and Karl L. Womer J Am Soc Nephrol 20: 831-841. [Abstract] [Full Text] [PDF]

CLINICAL EPIDEMIOLOGY

Probability, Predictors, and Prognosis of Posttransplantation Glomerulonephritis
Worawon Chailimpamontree, Svetlana Dmitrienko, Guiyun Li, Robert Balshaw, Alexander Magil, R. Jean Shapiro, David Landsberg, John Gill, Paul A. Keown and the Genome Canada Biomarkers in Transplantation Group J Am Soc Nephrol 20: 843-851. [Abstract] [Full Text] [PDF]

Screening for Albuminuria Identifies Individuals at Increased Renal Risk
Marije van der Velde, Nynke Halbesma, Frank T. de Charro, Stephan J.L. Bakker, Dick de Zeeuw, Paul E. de Jong, and Ronald T. Gansevoort J Am Soc Nephrol 20: 852-862. [Abstract] [Full Text] [PDF]

Fructose and Vitamin C Intake Do Not Influence Risk for Developing Hypertension
John P. Forman, Hyon Choi, and Gary C. Curhan J Am Soc Nephrol 20: 863-871. [Abstract] [Full Text] [PDF]

Anticoagulant and Antiplatelet Usage Associates with Mortality among Hemodialysis Patients
Kevin E. Chan, J. Michael Lazarus, Ravi Thadhani, and Raymond M. Hakim J Am Soc Nephrol 20: 872-881. [Abstract] [Full Text] [PDF]

CLINICAL RESEARCH

Lowering Blood Pressure Reduces Renal Events in Type 2 Diabetes
Bastiaan E. de Galan, Vlado Perkovic, Toshiharu Ninomiya, Avinesh Pillai, Anushka Patel, Alan Cass, Bruce Neal, Neil Poulter, Stephen Harrap, Carl-Erik Mogensen, Mark Cooper, Michel Marre, Bryan Williams, Pavel Hamet, Giuseppe Mancia, Mark Woodward, Paul Glasziou, Diederick E. Grobbee, Stephen MacMahon, John Chalmers on behalf of the ADVANCE Collaborative Group J Am Soc Nephrol 20: 883-892. [Abstract] [Full Text] [PDF]

Supramaximal Dose of Candesartan in Proteinuric Renal Disease
Ellen Burgess, Norman Muirhead, Paul Rene de Cotret, Anthony Chiu, Vincent Pichette, Sheldon Tobe the SMART (Supra Maximal Atacand Renal Trial) Investigators J Am Soc Nephrol 20: 893-900. [Abstract] [Full Text] [PDF]

Randomized, Controlled Trial of Prednisone, Cyclophosphamide, and Cyclosporine in Lupus Membranous Nephropathy
Howard A. Austin, III, Gabor G. Illei, Michelle J. Braun, and James E. Balow J Am Soc Nephrol 20: 901-911. [Abstract] [Full Text] [PDF]

Kidney Function Influences Warfarin Responsiveness and Hemorrhagic Complications
Nita A. Limdi, T. Mark Beasley, Melissa F. Baird, Joyce A. Goldstein, Gerald McGwin, Donna K. Arnett, Ronald T. Acton, and Michael Allon J Am Soc Nephrol 20: 912-921. [Abstract] [Full Text] [PDF]