TABLE OF CONTENTS: Volume 20, Issue 5, May 2009

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UP FRONT MATTERS

Obituary
Editorials
Brief Review
Special Article
Science in Renal Medicine

This Month's Highlights

BRIEF COMMUNICATIONS

BASIC RESEARCH

CLINICAL EPIDEMIOLOGY

CLINICAL RESEARCH

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This Month's Highlights

This Month's Highlights
J Am Soc Nephrol 20: A14. [Full Text] [PDF]

UP FRONT MATTERS

Obituary

A Tribute to Willem Johan Kolff, M.D., 1912–2009
Lee W. Henderson J Am Soc Nephrol 20: 923-924. [Full Text] [PDF]

Editorials

17 and 23: Prime Numbers that Matter
Sally Hamour and Alan D. Salama J Am Soc Nephrol 20: 925-927. [Full Text] [PDF]

Microvesicles from Mesenchymal Stromal Cells Protect against Acute Kidney Injury
Joseph V. Bonventre J Am Soc Nephrol 20: 927-928. [Full Text] [PDF]

CKD Classification: Time to Move Beyond KDOQI
T. Alp Ikizler J Am Soc Nephrol 20: 929-930. [Full Text] [PDF]

Lessons from Geographic Variations in Predialysis Nephrology Care
Wolfgang C. Winkelmayer J Am Soc Nephrol 20: 930-932. [Full Text] [PDF]

Brief Review

Sympathetic Activation in Chronic Renal Failure
Markus P. Schlaich, Flora Socratous, Sarah Hennebry, Nina Eikelis, Elisabeth A. Lambert, Nora Straznicky, Murray D. Esler, and Gavin W. Lambert J Am Soc Nephrol 20: 933-939. [Abstract] [Full Text] [PDF]

Special Article

Liver-Kidney Transplantation to Cure Atypical Hemolytic Uremic Syndrome
Jeffrey M. Saland, Piero Ruggenenti, Giuseppe Remuzzi and the Consensus Study Group J Am Soc Nephrol 20: 940-949. [Abstract] [Full Text] [PDF]

Science in Renal Medicine

Sensitizing the Slit Diaphragm with TRPC6 Ion Channels
Clemens C. Möller, Jan Flesche, and Jochen Reiser J Am Soc Nephrol 20: 950-953. [Abstract] [Full Text] [PDF]

BRIEF COMMUNICATIONS

Initial FGF23-Mediated Signaling Occurs in the Distal Convoluted Tubule
Emily G. Farrow, Siobhan I. Davis, Lelia J. Summers, and Kenneth E. White J Am Soc Nephrol 20: 955-960. [Abstract] [Full Text] [PDF]

Patients with ACTN4 Mutations Demonstrate Distinctive Features of Glomerular Injury
Joel M. Henderson, Mariam P. Alexander, and Martin R. Pollak J Am Soc Nephrol 20: 961-968. [Abstract] [Full Text] [PDF] [Supplemental Data]

BASIC RESEARCH

The IL-23/Th17 Axis Contributes to Renal Injury in Experimental Glomerulonephritis
Hans-Joachim Paust, Jan-Eric Turner, Oliver M. Steinmetz, Anett Peters, Felix Heymann, Christoph Hölscher, Gunter Wolf, Christian Kurts, Hans-Willi Mittrücker, Rolf A.K. Stahl, and Ulf Panzer J Am Soc Nephrol 20: 969-979. [Abstract] [Full Text] [PDF] [Supplemental Data]

IL-23, not IL-12, Directs Autoimmunity to the Goodpasture Antigen
Joshua D. Ooi, Richard K.S. Phoon, Stephen R. Holdsworth, and A. Richard Kitching J Am Soc Nephrol 20: 980-989. [Abstract] [Full Text] [PDF] [Supplemental Data]

LIP5 Interacts with Aquaporin 2 and Facilitates Its Lysosomal Degradation
Bas W.M. van Balkom, Michelle Boone, Giel Hendriks, Erik-Jan Kamsteeg, Joris H. Robben, H. Christiaan Stronks, Anne van der Voorde, Francois van Herp, Peter van der Sluijs, and Peter M.T. Deen J Am Soc Nephrol 20: 990-1001. [Abstract] [Full Text] [PDF] [Supplemental Data]

Activation of the Succinate Receptor GPR91 in Macula Densa Cells Causes Renin Release
Sarah Laurin Vargas, Ildikó Toma, Jung Julie Kang, Elliott James Meer, and János Peti-Peterdi J Am Soc Nephrol 20: 1002-1011. [Abstract] [Full Text] [PDF]

Reactive Immunization Suppresses Advanced Glycation and Mitigates Diabetic Nephropathy
Tatiana Shcheglova, Sudesh Makker, and Alfonso Tramontano J Am Soc Nephrol 20: 1012-1019. [Abstract] [Full Text] [PDF]

Chordin-like 1 and Twisted Gastrulation 1 Regulate BMP Signaling following Kidney Injury
Barry W. Larman, Michele J. Karolak, Derek C. Adams, and Leif Oxburgh J Am Soc Nephrol 20: 1020-1031. [Abstract] [Full Text] [PDF] [Supplemental Data]

IL-6 and TNF- ${alpha}$ Synergistically Inhibit Allograft Acceptance
Hua Shen and Daniel R. Goldstein J Am Soc Nephrol 20: 1032-1040. [Abstract] [Full Text] [PDF] [Supplemental Data]

Urine Podocyte mRNAs Mark Progression of Renal Disease
Yuji Sato, Bryan L. Wharram, Sang Koo Lee, Larysa Wickman, Meera Goyal, Madhusudan Venkatareddy, Jai Won Chang, Jocelyn E. Wiggins, Chrysta Lienczewski, Matthias Kretzler, and Roger C. Wiggins J Am Soc Nephrol 20: 1041-1052. [Abstract] [Full Text] [PDF]

Mesenchymal Stem Cell-Derived Microvesicles Protect Against Acute Tubular Injury
Stefania Bruno, Cristina Grange, Maria Chiara Deregibus, Raffaele A. Calogero, Silvia Saviozzi, Federica Collino, Laura Morando, Alessandro Busca, Michele Falda, Benedetta Bussolati, Ciro Tetta, and Giovanni Camussi J Am Soc Nephrol 20: 1053-1067. [Abstract] [Full Text] [PDF]

CLINICAL EPIDEMIOLOGY

Combining GFR and Albuminuria to Classify CKD Improves Prediction of ESRD
Stein I. Hallan, Eberhard Ritz, Stian Lydersen, Solfrid Romundstad, Kurt Kvenild, and Stephan R. Orth J Am Soc Nephrol 20: 1069-1077. [Abstract] [Full Text] [PDF] [Press Release]

Treatment Center and Geographic Variability in Pre-ESRD Care Associate with Increased Mortality
William M. McClellan, Haimanot Wasse, Ann C. McClellan, Adam Kipp, Lance A. Waller, and Michael V. Rocco J Am Soc Nephrol 20: 1078-1085. [Abstract] [Full Text] [PDF]

Cystatin C Associates with Arterial Stiffness in Older Adults
Magdalena Madero, Christina L. Wassel, Carmen A. Peralta, Samer S. Najjar, Kim Sutton-Tyrrell, Linda Fried, Robert Canada, Anne Newman, Michael G. Shlipak, Mark J. Sarnak for the Health ABC Study J Am Soc Nephrol 20: 1086-1093. [Abstract] [Full Text] [PDF]

Rosiglitazone Is Associated with Mortality in Chronic Hemodialysis Patients
Sylvia P.B. Ramirez, Justin M. Albert, Margaret J. Blayney, Francesca Tentori, David A. Goodkin, Robert A. Wolfe, Eric W. Young, George R. Bailie, Ronald L. Pisoni, and Friedrich K. Port J Am Soc Nephrol 20: 1094-1101. [Abstract] [Full Text] [PDF]

CLINICAL RESEARCH

Mycophenolate Mofetil versus Cyclophosphamide for Induction Treatment of Lupus Nephritis
Gerald B. Appel, Gabriel Contreras, Mary Anne Dooley, Ellen M. Ginzler, David Isenberg, David Jayne, Lei-Shi Li, Eduardo Mysler, Jorge Sánchez-Guerrero, Neil Solomons, David Wofsy the Aspreva Lupus Management Study Group J Am Soc Nephrol 20: 1103-1112. [Abstract] [Full Text] [PDF] [Supplemental Data][Press Release]

Regulatory, Effector, and Cytotoxic T Cell Profiles in Long-Term Kidney Transplant Patients
Joanna Ashton-Chess, Emilie Dugast, Robert B. Colvin, Magali Giral, Yohann Foucher, Anne Moreau, Karine Renaudin, Christophe Braud, Anne Devys, Sophie Brouard, and Jean-Paul Soulillou J Am Soc Nephrol 20: 1113-1122. [Abstract] [Full Text] [PDF] [Supplemental Data]

HNF1B Mutations Associate with Hypomagnesemia and Renal Magnesium Wasting
Shazia Adalat, Adrian S. Woolf, Karen A. Johnstone, Andrea Wirsing, Lorna W. Harries, David A. Long, Raoul C. Hennekam, Sarah E. Ledermann, Lesley Rees, William van't Hoff, Stephen D. Marks, Richard S. Trompeter, Kjell Tullus, Paul J. Winyard, Janette Cansick, Imran Mushtaq, Harjeeta K. Dhillon, Coralie Bingham, Emma L. Edghill, Rukshana Shroff, Horia Stanescu, Gerhart U. Ryffel, Sian Ellard, and Detlef Bockenhauer J Am Soc Nephrol 20: 1123-1131. [Abstract] [Full Text] [PDF]

Agalsidase Alfa and Kidney Dysfunction in Fabry Disease
Michael West, Kathy Nicholls, Atul Mehta, Joe T.R. Clarke, Robert Steiner, Michael Beck, Bruce A. Barshop, William Rhead, Robert Mensah, Markus Ries, and Raphael Schiffmann J Am Soc Nephrol 20: 1132-1139. [Abstract] [Full Text] [PDF] [Press Release]

Plasma Gelsolin and Circulating Actin Correlate with Hemodialysis Mortality
Po-Shun Lee, Kartik Sampath, S. Ananth Karumanchi, Hector Tamez, Ishir Bhan, Tamara Isakova, Orlando M. Gutierrez, Myles Wolf, Yuchiao Chang, Thomas P. Stossel, and Ravi Thadhani J Am Soc Nephrol 20: 1140-1148. [Abstract] [Full Text] [PDF] [Supplemental Data]

Molecular Correlates of Renal Function in Kidney Transplant Biopsies
Sakarn Bunnag, Gunilla Einecke, Jeff Reeve, Gian S. Jhangri, Thomas F. Mueller, Banu Sis, Luis G. Hidalgo, Michael Mengel, Daniel Kayser, Bruce Kaplan, and Philip F. Halloran J Am Soc Nephrol 20: 1149-1160. [Abstract] [Full Text] [PDF] [Supplemental Data]