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- Table 1.
GFR, peritoneal creatinine clearance, and fluid removal at volumes baseline and at 6, 12, 18, and 24 months of follow-upa
Parameter Baseline 6 Mo 12 Mo 18 Mo 24 Mo aCcrp, peritoneal creatinine clearance; UF, ultrafiltration. GFR and Ccrp are normalized to 1.73 m2. n 601 469 290 147 69 GFR (L/wk) 37.7 28.7 21.4 19.4 14.8 Ccrp (L/wk) 44.3 45.8 46.4 45.3 47.2 Urine volume (ml/24 h) 670 519 428 379 335 Net peritoneal UF (ml/24 h) 958 1478 1807 1677 1951 Total fluid removal (ml/24 h) 1628 1997 2235 2056 2286 - Table 2.
Cox model of relative risk of death with time-dependent Ccr divided into peritoneal clearance and GFR and entered as time-dependent covariatesa
Variable Relative Risk 95% Confidence Limit aCVD, cardiovascular disease; LA, low average; HA, high average; H, high; SGA, subjective global assessment. Age 1.02 1.005-1.044 CVD 2.42 1.499-3.904 Diabetes mellitus 1.25 0.769-2.036 Serum albumin 0.96 0.912-1.000 LA transport 1.66 0.379-7.218 HA transport 2.33 0.554-9.801 H transport 2.01 0.430-9.357 SGA 0.74 0.647-0.842 Ccrp (5 L/wk per 1.73 m2 greater) 1.00 0.898-1.105 GFR (5 L/wk per 1.73 m2 greater) 0.88 0.829-0.943 - Table 3.
Cox model of relative risk for death with urine volume forced in as a time-dependent covariate
Variable Relative Risk 95% Confidence Limits Age (1 yr older) 1.02 1.002-1.041 CVD 2.37 1.465-3.821 Diabetes mellitus 1.31 0.807-2.134 Serum albumin (1 g/L increase) 0.96 0.914-1.003 LA transport 1.84 0.418-8.075 HA transport 2.71 0.631-11.623 H transport 2.46 0.523-11.590 SGA (1 unit greater) 0.78 0.672-0.876 Ccrp (5 L/wk per 1.73 m2 greater) 0.93 0.795-1.079 GFR (5 L/wk per 1.73 m2 greater) 0.99 0.943-1.044 Urine volume (250 ml daily greater) 0.64 0.508-0.800
Relative Contribution of Residual Renal Function and Peritoneal Clearance to Adequacy of Dialysis: A Reanalysis of the CANUSA Study
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