Journal of the American Society of Nephrology: 13 (9)

September 01, 2002; Volume 13,Issue 9

THIS MONTH'S HIGHLIGHTS

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This Month’s Highlights
JASN September 2002, 13 (9) A10-A12; DOI: https://doi.org/10.1681/ASN.V139a10

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ASN NEWS

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ASN News
JASN September 2002, 13 (9) A17-A18; DOI: https://doi.org/10.1681/ASN.V139a17

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Cell and Transport Physiology

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Regulation of the Proximal Tubular Sodium/Proton Exchanger NHE3 in Rats with Puromycin Aminonucleoside (PAN)-Induced Nephrotic Syndrome
Valérie Besse-Eschmann, Jelena Klisic, Vera Nief, Michel Le Hir, Brigitte Kaissling and Patrice M. Ambühl

JASN September 2002, 13 (9) 2199-2206; DOI: https://doi.org/10.1097/01.ASN.0000028839.52271.DF

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Hemodynamics, Hypertension, and Vascular Regulation

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Renal Interstitial Fluid Angiotensin I and Angiotensin II Concentrations during Local Angiotensin-Converting Enzyme Inhibition
Akira Nishiyama, Dale M. Seth and L. Gabriel Navar

JASN September 2002, 13 (9) 2207-2212; DOI: https://doi.org/10.1097/01.ASN.0000026610.48842.CB

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Prognostic Significance of Renal Function in Elderly Patients with Isolated Systolic Hypertension: Results from the Syst-Eur Trial
Peter W. de Leeuw, Lutgarde Thijs, Willem H. Birkenhäger, Sophia M. Voyaki, Aris D. Efstratopoulos, Robert H. Fagard, Gastone Leonetti, Choudomir Nachev, James C. Petrie, José L. Rodicio, Joseph J. Rosenfeld, Cinzia Sarti, Jan A. Staessen and ; for the Systolic Hypertension in Europe (Syst-Eur) Trial Investigators

JASN September 2002, 13 (9) 2213-2222; DOI: https://doi.org/10.1097/01.ASN.0000027871.86296.92

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Immunology and Pathology

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PPAR Agonists Amplify iNOS Expression While Inhibiting NF-κB: Implications for Mesangial Cell Activation by Cytokines
Eva Cernuda-Morollón, Fernando Rodríguez-Pascual, Peter Klatt, Santiago Lamas and Dolores Pérez-Sala

JASN September 2002, 13 (9) 2223-2231; DOI: https://doi.org/10.1097/01.ASN.0000025786.87646.B1

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Neutrophil Membrane Expression of Proteinase 3 (PR3) Is Related to Relapse in PR3-ANCA-Associated Vasculitis
Agnieszka A. Rarok, Coen A. Stegeman, Pieter C. Limburg and Cees G. M. Kallenberg

JASN September 2002, 13 (9) 2232-2238; DOI: https://doi.org/10.1097/01.ASN.0000028642.26222.00

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Molecular Basis for High Renal Cell Sensitivity to the Cytotoxic Effects of Shigatoxin-1: Upregulation of Globotriaosylceramide Expression
Alisa K. Hughes, Zuhal Ergonul, Peter K. Stricklett and Donald E. Kohan

JASN September 2002, 13 (9) 2239-2245; DOI: https://doi.org/10.1097/01.ASN.0000027873.85792.52

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Molecular Medicine, Genetics and Development

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Identification and Characterization of Pkhd1, the Mouse Orthologue of the Human ARPKD Gene
Yasuyuki Nagasawa, Sonja Matthiesen, Luiz F. Onuchic, Xiaoying Hou, Carsten Bergmann, Ernie Esquivel, Jan Senderek, Zhiyong Ren, Raoul Zeltner, Laszlo Furu, Ellis Avner, Markus Moser, Stefan Somlo, Lisa Guay-Woodford, Reinhard Büttner, Klaus Zerres and Gregory G. Germino

JASN September 2002, 13 (9) 2246-2258; DOI: https://doi.org/10.1097/01.ASN.0000030392.19694.9D

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Pathophysiology of Renal Disease

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Functional Characterization of a Calcium-Sensing Receptor Mutation in Severe Autosomal Dominant Hypocalcemia with a Bartter-Like Syndrome
Rosa Vargas-Poussou, Chunfa Huang, Philippe Hulin, Pascal Houillier, Xavier Jeunemaître, Michel Paillard, Gabrielle Planelles, Michèle Déchaux, R. Tyler Miller and Corinne Antignac

JASN September 2002, 13 (9) 2259-2266; DOI: https://doi.org/10.1097/01.ASN.0000025781.16723.68

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Cell-Biologic and Functional Analyses of Five New Aquaporin-2 Missense Mutations that Cause Recessive Nephrogenic Diabetes Insipidus
Nannette Marr, Daniel G. Bichet, Susan Hoefs, Paul J. M. Savelkoul, Irene B. M. Konings, Fabrizio de Mattia, Michael P. J. Graat, Marie-Françoise Arthus, Michele Lonergan, T. Mary Fujiwara, Nine V. A. M. Knoers, Daniel Landau, William J. Balfe, Alexander Oksche, Walter Rosenthal, Dominik Müller, Carel H. van Os and Peter M. T. Deen

JASN September 2002, 13 (9) 2267-2277; DOI: https://doi.org/10.1097/01.ASN.0000027355.41663.14

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Evidence for the Existence of Two Distinct Functions for the Inducible NO Synthase in the Rat Kidney: Effect of Aminoguanidine in Rats with 5/6 Ablation
Clarice Kazue Fujihara, Ana Lúcia Mattar, José Mauro Vieira, Denise Maria Avancini Costa Malheiros, Irene de Lourdes Noronha, Anderson Ricardo Roman Gonçalves, Gilberto de Nucci and Roberto Zatz

JASN September 2002, 13 (9) 2278-2287; DOI: https://doi.org/10.1097/01.ASN.0000027354.12330.F4

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Postischemic Acute Renal Failure Is Reduced by Short-Term Statin Treatment in a Rat Model
Faikah Gueler, Song Rong, Joon-Keun Park, Anette Fiebeler, Jan Menne, Marlies Elger, Dominik N. Mueller, Franziska Hampich, Ralf Dechend, Uta Kunter, Friedrich C. Luft and Hermann Haller

JASN September 2002, 13 (9) 2288-2298; DOI: https://doi.org/10.1097/01.ASN.0000026609.45827.3D

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Mineral Metabolism and Bone Disease

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The Effects of Sevelamer Hydrochloride and Calcium Carbonate on Kidney Calcification in Uremic Rats
Mario Cozzolino, Adriana S. Dusso, Helen Liapis, Jane Finch, Yan Lu, Steven K. Burke and Eduardo Slatopolsky

JASN September 2002, 13 (9) 2299-2308; DOI: https://doi.org/10.1097/01.ASN.0000025782.24383.0D

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Clinical Nephrology

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Characteristics of Polymeric λ-IgA Binding to Leukocytes in IgA Nephropathy
Kar Neng Lai, Loretta Y. Y. Chan, Sydney C. W. Tang, Anita W. L. Tsang, Hong Guo, Kai Chung Tse, Terrance Yip and Joseph C. K. Leung

JASN September 2002, 13 (9) 2309-2319; DOI: https://doi.org/10.1097/01.ASN.0000026497.82930.73

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Molecular Identification of SV40 Infection in Human Subjects and Possible Association with Kidney Disease
Rui-Mei Li, Mary H. Branton, Somsak Tanawattanacharoen, Ronald A. Falk, J. Charles Jennette and Jeffrey B. Kopp

JASN September 2002, 13 (9) 2320-2330; DOI: https://doi.org/10.1097/01.ASN.0000028249.06596.CF

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Low-Intensity Warfarin Is Ineffective for the Prevention of PTFE Graft Failure in Patients on Hemodialysis: A Randomized Controlled Trial
Mark A. Crowther, Catherine M. Clase, Peter J. Margetts, Jim Julian, Kim Lambert, Denise Sneath, Ryuta Nagai, Sarah Wilson and Alistair J. Ingram

JASN September 2002, 13 (9) 2331-2337; DOI: https://doi.org/10.1097/01.ASN.0000027356.16598.99

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Dialysis

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Measuring the Efficacy of a Quality Improvement Program in Dialysis Adequacy with Changes in Center Effects
Jeffrey C. Fink, Min Zhan, Steven A. Blahut, Michael Soucie and William M. McClellan

JASN September 2002, 13 (9) 2338-2344; DOI: https://doi.org/10.1097/01.ASN.0000027978.98194.1F

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Seasonal Variations in Clinical and Laboratory Variables among Chronic Hemodialysis Patients
Alfred K. Cheung, Guofen Yan, Tom Greene, John T. Daugirdas, Johanna T. Dwyer, Nathan W. Levin, Daniel B. Ornt, Gerald Schulman, Garabed Eknoyan and ; the Hemodialysis Study Group

JASN September 2002, 13 (9) 2345-2352; DOI: https://doi.org/10.1097/01.ASN.0000026611.07106.A7

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Epidemiology and Outcomes

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Comparing Mortality of Elderly Patients on Hemodialysis versus Peritoneal Dialysis: A Propensity Score Approach
Wolfgang C. Winkelmayer, Robert J. Glynn, Murray A. Mittleman, Raisa Levin, Joseph S. Pliskin and Jerry Avorn

JASN September 2002, 13 (9) 2353-2362; DOI: https://doi.org/10.1097/01.ASN.0000025785.41314.76

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Excess Risk of Chronic Kidney Disease among African-American versus White Subjects in the United States: A Population-Based Study of Potential Explanatory Factors
Michelle E. Tarver-Carr, Neil R. Powe, Mark S. Eberhardt, Thomas A. LaVeist, Raynard S. Kington, Josef Coresh and Frederick L. Brancati

JASN September 2002, 13 (9) 2363-2370; DOI: https://doi.org/10.1097/01.ASN.0000026493.18542.6A

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Transplantation

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Capillary Deposition of Complement Split Product C4d in Renal Allografts is Associated with Basement Membrane Injury in Peritubular and Glomerular Capillaries: A Contribution of Humoral Immunity to Chronic Allograft Rejection
Heinz Regele, Georg A. Böhmig, Antje Habicht, Daniela Gollowitzer, Martin Schillinger, Susanne Rockenschaub, Bruno Watschinger, Dontscho Kerjaschki and Markus Exner

JASN September 2002, 13 (9) 2371-2380; DOI: https://doi.org/10.1097/01.ASN.0000025780.03790.0F

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BRIEF COMMUNICATIONS

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Allergic Skin and Systemic Reactions in a Patient with Pure Red Cell Aplasia and Anti-Erythropoietin Antibodies Challenged with Different Epoetins
Gertrud Weber, Johann Gross, Arno Kromminga, Hans-H. Loew and Kai-Uwe Eckardt

JASN September 2002, 13 (9) 2381-2383; DOI: https://doi.org/10.1097/01.ASN.0000027031.79843.6C

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DISEASE OF THE MONTH

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Genetics and Pathogenesis of Polycystic Kidney Disease
Peter Igarashi, Stefan Somlo and ; Feature Editor

JASN September 2002, 13 (9) 2384-2398; DOI: https://doi.org/10.1097/01.ASN.0000028643.17901.42

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REVIEWS

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Disturbances of Na/K Balance: Pseudohypoaldosteronism Revisited
Olivier Bonny and Bernard C. Rossier

JASN September 2002, 13 (9) 2399-2414; DOI: https://doi.org/10.1097/01.ASN.0000028641.59030.B2

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EDITORIALS

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Chronic Kidney Disease and Cardiovascular Risk: Time to Focus on Therapy
Donal N. Reddan and Preston S. Klassen

JASN September 2002, 13 (9) 2415-2416; DOI: https://doi.org/10.1097/01.ASN.0000030306.16107.AE

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C4d and the Fate of Organ Allografts
Jeffrey L. Platt

JASN September 2002, 13 (9) 2417-2419; DOI: https://doi.org/10.1097/01.ASN.0000030140.74450.0B

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Capillary C4d Deposition as a Marker of Humoral Immunity in Renal Allograft Rejection
Bruno Watschinger and Manuel Pascual

JASN September 2002, 13 (9) 2420-2423; DOI: https://doi.org/10.1097/01.ASN.0000029941.34837.22

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ANNOUNCEMENTS

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JASN September 2002, 13 (9) 2424; DOI: https://doi.org/10.1681/ASN.V1392424

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Table of Contents

THIS MONTH'S HIGHLIGHTS

ASN NEWS

Cell and Transport Physiology

Hemodynamics, Hypertension, and Vascular Regulation

Immunology and Pathology

Molecular Medicine, Genetics and Development

Pathophysiology of Renal Disease

Mineral Metabolism and Bone Disease

Clinical Nephrology

Dialysis

Epidemiology and Outcomes

Transplantation

BRIEF COMMUNICATIONS

DISEASE OF THE MONTH

REVIEWS

EDITORIALS

ANNOUNCEMENTS

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