Journal of the American Society of Nephrology: 14 (4)

April 01, 2003; Volume 14,Issue 4

THIS MONTH'S HIGHLIGHTS

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This Month’s Highlights
JASN April 2003, 14 (4) A9-A11; DOI: https://doi.org/10.1681/ASN.V144a9

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ASN NEWS

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ASN NEWS
JASN April 2003, 14 (4) A29-A30; DOI: https://doi.org/10.1681/ASN.V144a29

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Cell and Transport Physiology

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Na Transport in Autosomal Recessive Polycystic Kidney Disease (ARPKD) Cyst Lining Epithelial Cells
Rajeev Rohatgi, Andrew Greenberg, Christopher R. Burrow, Patricia D. Wilson and Lisa M. Satlin

JASN April 2003, 14 (4) 827-836; DOI: https://doi.org/10.1097/01.ASN.0000056481.66379.B2

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Basolateral LAT-2 Has a Major Role in the Transepithelial Flux of L-Cystine in the Renal Proximal Tubule Cell Line OK
Esperanza Fernández, David Torrents, Josep Chillarón, Rafael Martín del Río, Antonio Zorzano and Manuel Palacín

JASN April 2003, 14 (4) 837-847; DOI: https://doi.org/10.1097/01.ASN.0000057852.35075.AC

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Hormones, Growth Factors, Cell Signaling, Cell Biology and Structure

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Ras Antagonist Farnesylthiosalicylic Acid (FTS) Reduces Glomerular Cellular Proliferation and Macrophage Number in Rat Thy-1 Nephritis
Helen C. Clarke, Hemant M. Kocher, Arif Khwaja, Yoel Kloog, H. Terence Cook and Bruce M. Hendry

JASN April 2003, 14 (4) 848-854; DOI: https://doi.org/10.1097/01.ASN.0000057543.55318.8B

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Activation of Pro-Apoptotic Cascade by Dopamine in Renal Epithelial Cells is Fully Dependent on Hydrogen Peroxide Generation by Monoamine Oxidases
Pascale Bianchi, Marie-Hélène Séguélas, Angelo Parini and Claudie Cambon

JASN April 2003, 14 (4) 855-862; DOI: https://doi.org/10.1097/01.ASN.0000058909.00567.5C

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N-Acetyl-Seryl-Aspartyl-Lysyl-Proline Inhibits TGF-β–Mediated Plasminogen Activator Inhibitor-1 Expression via Inhibition of Smad Pathway in Human Mesangial Cells
Keizo Kanasaki, Daisuke Koya, Toshiro Sugimoto, Motohide Isono, Atsunori Kashiwagi and Masakazu Haneda

JASN April 2003, 14 (4) 863-872; DOI: https://doi.org/10.1097/01.ASN.0000057544.95569.EC

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Mechanism of Increased Angiotensin II Levels in Glomerular Mesangial Cells Cultured in High Glucose
Rekha Singh, Ashok K. Singh, Nahid Alavi and David J. Leehey

JASN April 2003, 14 (4) 873-880; DOI: https://doi.org/10.1097/01.ASN.0000060804.40201.6E

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Hemodynamics, Hypertension and Vascular Regulation

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Left Ventricular Remodeling and Renal Function in Never-Treated Essential Hypertension
Pierre Fesler, Guilhem du Cailar, Jean Ribstein and Albert Mimran

JASN April 2003, 14 (4) 881-887; DOI: https://doi.org/10.1097/01.ASN.0000057855.93268.9F

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Immunology and Pathology

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Interferon-γ Augments Acute Macrophage-Mediated Renal Injury Via a Glucocorticoid-Sensitive Mechanism
Yohei Ikezumi, Robert C. Atkins and David J. Nikolic-Paterson

JASN April 2003, 14 (4) 888-898; DOI: https://doi.org/10.1097/01.ASN.0000056604.13964.62

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Renal mRNA Levels as Prognostic Tools in Kidney Diseases
Michael Eikmans, Hans J. Baelde, E. Chris Hagen, Leendert C. Paul, Paul H. C. Eilers, Emile de Heer and Jan A. Bruijn

JASN April 2003, 14 (4) 899-907; DOI: https://doi.org/10.1097/01.ASN.0000056611.92730.7B

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Atubular Glomeruli and Glomerulotubular Junction Abnormalities in Diabetic Nephropathy
Behzad Najafian, Youngki Kim, John T. Crosson and Michael Mauer

JASN April 2003, 14 (4) 908-917; DOI: https://doi.org/10.1097/01.ASN.0000057854.32413.81

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Molecular Medicine, Genetics and Development

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Homodimerization and Heterodimerization of the Glomerular Podocyte Proteins Nephrin and NEPH1
Peter Gerke, Tobias B. Huber, Lorenz Sellin, Thomas Benzing and Gerd Walz

JASN April 2003, 14 (4) 918-926; DOI: https://doi.org/10.1097/01.ASN.0000057853.05686.89

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Podocyte Expression of Hypoxia-Inducible Factor (HIF)–1 and HIF–2 during Glomerular Development
Paul B. Freeburg, Barry Robert, Patricia L. St. John and Dale R. Abrahamson

JASN April 2003, 14 (4) 927-938; DOI: https://doi.org/10.1097/01.ASN.0000059308.82322.4F

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Control of Oxalate Formation from L-Hydroxyproline in Liver Mitochondria
Tatsuya Takayama, Kimio Fujita, Kazuo Suzuki, Michiko Sakaguchi, Michio Fujie, Erina Nagai, Shinya Watanabe, Arata Ichiyama and Yoshihide Ogawa

JASN April 2003, 14 (4) 939-946; DOI: https://doi.org/10.1097/01.ASN.0000059310.67812.4F

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Gene Delivery in Renal Tubular Epithelial Cells Using Recombinant Adeno-Associated Viral Vectors
Sifeng Chen, Anupam Agarwal, Olena Y. Glushakova, Marda S. Jorgensen, Shashikumar K. Salgar, Amy Poirier, Terence R. Flotte, Byron P. Croker, Kirsten M. Madsen, Mark A. Atkinson, William W. Hauswirth, Kenneth I. Berns and C. Craig Tisher

JASN April 2003, 14 (4) 947-958; DOI: https://doi.org/10.1097/01.ASN.0000057858.45649.F7

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Pathophysiology of Renal Disease

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Beneficial Effects of Calcimimetics on Progression of Renal Failure and Cardiovascular Risk Factors
Hiroaki Ogata, Eberhard Ritz, Giulio Odoni, Kerstin Amann and Stephan R. Orth

JASN April 2003, 14 (4) 959-967; DOI: https://doi.org/10.1097/01.ASN.0000056188.23717.E5

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Amelioration of Diabetic Nephropathy in SPARC-Null Mice
Sekiko Taneda, Jeffrey W. Pippin, E. Helene Sage, Kelly L. Hudkins, Yasuo Takeuchi, William G. Couser and Charles E. Alpers

JASN April 2003, 14 (4) 968-980; DOI: https://doi.org/10.1097/01.ASN.0000054498.83125.90

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Retinoids Regulate the Repairing Process of the Podocytes in Puromycin Aminonucleoside-induced Nephrotic Rats
Akira Suzuki, Takahito Ito, Enyu Imai, Masaya Yamato, Hirotsugu Iwatani, Hiroshi Kawachi and Masatsugu Hori

JASN April 2003, 14 (4) 981-991; DOI: https://doi.org/10.1097/01.ASN.0000057857.66268.8F

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Clinical Nephrology

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Additive Effect of ACE Inhibition and Angiotensin II Receptor Blockade in Type I Diabetic Patients with Diabetic Nephropathy
Peter Jacobsen, Steen Andersen, Berit R. Jensen and Hans-Henrik Parving

JASN April 2003, 14 (4) 992-999; DOI: https://doi.org/10.1097/01.ASN.0000054495.96193.BF

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Dialysis

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Creatinine Production, Nutrition, and Glomerular Filtration Rate Estimation
Srinivasan Beddhu, Matthew H. Samore, Mark S. Roberts, Gregory J. Stoddard, Lisa M. Pappas and Alfred K. Cheung

JASN April 2003, 14 (4) 1000-1005; DOI: https://doi.org/10.1097/01.ASN.0000057856.88335.DD

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Sustained-Release Diltiazem Reduces Myocardial Ischemic Episodes in End-Stage Renal Disease: A Double-Blind, Randomized, Crossover, Placebo-Controlled Trial
Gennaro Cice, Attilio Di Benedetto, Antonello D’Andrea, Salvatore D’Isa, Luigi Ferrara, Pina Elvira Russo, Aldo Iacono and Raffaele Calabrò

JASN April 2003, 14 (4) 1006-1011; DOI: https://doi.org/10.1097/01.ASN.0000059309.66107.FC

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Epidemiology and Outcomes

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Octogenarians Reaching End-Stage Renal Disease: Cohort Study of Decision-Making and Clinical Outcomes
Dominique Joly, Dany Anglicheau, Corinne Alberti, Anh-Thu Nguyen, Malik Touam, Jean-Pierre Grünfeld and Paul Jungers

JASN April 2003, 14 (4) 1012-1021; DOI: https://doi.org/10.1097/01.ASN.0000054493.04151.80

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Acute Renal Failure in Patients with Sepsis in a Surgical ICU: Predictive Factors, Incidence, Comorbidity, and Outcome
Eric A.J. Hoste, Norbert H. Lameire, Raymond C. Vanholder, Dominique D. Benoit, Johan M.A. Decruyenaere and Francis A. Colardyn

JASN April 2003, 14 (4) 1022-1030; DOI: https://doi.org/10.1097/01.ASN.0000059863.48590.E9

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Transplantation

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Dual Kidneys from Marginal Adult Donors as a Source For Cadaveric Renal Transplantation in the United States
Suphamai Bunnapradist, H. Albin Gritsch, Alice Peng, Stanley C. Jordan and Yong W. Cho

JASN April 2003, 14 (4) 1031-1036; DOI: https://doi.org/10.1097/01.ASN.0000054494.85680.1C

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Delayed Graft Function and Cast Nephropathy Associated with Tacrolimus Plus Rapamycin Use
Kelly D. Smith, Lucile E. Wrenshall, Roberto F. Nicosia, Raimund Pichler, Christopher L. Marsh, Charles E. Alpers, Nayak Polissar and Connie L. Davis

JASN April 2003, 14 (4) 1037-1045; DOI: https://doi.org/10.1097/01.ASN.0000057542.86377.5A

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The Impact of Repeated Subclinical Acute Rejection on the Progression of Chronic Allograft Nephropathy
Seiichirou Shishido, Hiroshi Asanuma, Hideo Nakai, Yoshiaki Mori, Hiroyuki Satoh, Isamu Kamimaki, Hiroshi Hataya, Masahiro Ikeda, Masataka Honda and Akira Hasegawa

JASN April 2003, 14 (4) 1046-1052; DOI: https://doi.org/10.1097/01.ASN.0000056189.02819.32

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A Novel Mechanism for the Immunomodulatory Functions of Class II MHC–Derived Peptides
Barbara Murphy, Joyce Yu, Qingsheng Jiao, Marvin Lin, Tanuja Chitnis and Mohamed H. Sayegh

JASN April 2003, 14 (4) 1053-1065; DOI: https://doi.org/10.1097/01.ASN.0000057541.69641.F8

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BRIEF COMMUNICATIONS

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Gene Therapy Expressing Amino-Terminal Truncated Monocyte Chemoattractant Protein-1 Prevents Renal Ischemia-Reperfusion Injury
Kengo Furuichi, Takashi Wada, Yasunori Iwata, Kiyoki Kitagawa, Ken-ichi Kobayashi, Hiroyuki Hashimoto, Yoshiro Ishiwata, Naohisa Tomosugi, Naofumi Mukaida, Kouji Matsushima, Kensuke Egashira and Hitoshi Yokoyama

JASN April 2003, 14 (4) 1066-1071; DOI: https://doi.org/10.1097/01.ASN.0000059339.14780.E4

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DISEASE OF THE MONTH

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Advances in the Pathogenesis, Diagnosis, and Treatment of Thrombotic Thrombocytopenic Purpura
Han-Mou Tsai

JASN April 2003, 14 (4) 1072-1081; DOI: https://doi.org/10.1097/01.ASN.0000060805.04118.4C

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REVIEWS

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Molecular Mechanisms of Primary Hypercalciuria
Kevin K. Frick and David A. Bushinsky

JASN April 2003, 14 (4) 1082-1095; DOI: https://doi.org/10.1097/01.ASN.0000062960.26868.17

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EDITORIALS

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Windows on Renal Biopsy Interpretation: Does mRNA Analysis Represent a New Gold Standard?
Liliane J. Striker and Gary E. Striker

JASN April 2003, 14 (4) 1096-1098; DOI: https://doi.org/10.1097/01.ASN.0000060865.30249.40

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Geriatric Nephrology is Coming of Age
Dimitrios G. Oreopoulos and Nada Dimkovic

JASN April 2003, 14 (4) 1099-1101; DOI: https://doi.org/10.1097/01.ASN.0000067656.48829.0E

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Gene Therapy for Renal Diseases: Its Potential and Limitation
Enyu Imai

JASN April 2003, 14 (4) 1102-1104; DOI: https://doi.org/10.1097/01.ASN.0000067655.48829.D5

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ANNOUNCEMENTS

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JASN April 2003, 14 (4) 1105; DOI: https://doi.org/10.1681/ASN.V1441105

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Table of Contents

THIS MONTH'S HIGHLIGHTS

ASN NEWS

Cell and Transport Physiology

Hormones, Growth Factors, Cell Signaling, Cell Biology and Structure

Hemodynamics, Hypertension and Vascular Regulation

Immunology and Pathology

Molecular Medicine, Genetics and Development

Pathophysiology of Renal Disease

Clinical Nephrology

Dialysis

Epidemiology and Outcomes

Transplantation

BRIEF COMMUNICATIONS

DISEASE OF THE MONTH

REVIEWS

EDITORIALS

ANNOUNCEMENTS

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