Journal of the American Society of Nephrology: 14 (8)

August 01, 2003; Volume 14,Issue 8

THIS MONTH'S HIGHLIGHTS

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This Month’s Highlights
JASN August 2003, 14 (8) A9-A11; DOI: https://doi.org/10.1681/ASN.V148a9

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ASN NEWS

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ASN News
JASN August 2003, 14 (8) A25-A26; DOI: https://doi.org/10.1681/ASN.V148a25

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Cell and Transport Physiology

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Protein Kinase C Activation Downregulates Human Organic Anion Transporter 1-Mediated Transport through Carrier Internalization
Natascha A. Wolff, Karen Thies, Nicola Kuhnke, Glen Reid, Björn Friedrich, Florian Lang and Gerhard Burckhardt

JASN August 2003, 14 (8) 1959-1968; DOI: https://doi.org/10.1097/01.ASN.0000079040.55124.25

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Hormones, Growth Factors, Cell Signaling, Cell Biology and Structure

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Cytoskeletal Rearrangement and Signal Transduction in TGF-β1–Stimulated Mesangial Cell Collagen Accumulation
Susan C. Hubchak, Constance E. Runyan, Jeffrey I. Kreisberg and H. William Schnaper

JASN August 2003, 14 (8) 1969-1980; DOI: https://doi.org/10.1097/01.ASN.0000076079.02452.92

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Immunology and Pathology

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Lymphatic Microvessels in the Rat Remnant Kidney Model of Renal Fibrosis: Aminopeptidase P and Podoplanin Are Discriminatory Markers for Endothelial Cells of Blood and Lymphatic Vessels
Katsuyuki Matsui, Katalyn Nagy-Bojarsky, Pirjo Laakkonen, Sigurd Krieger, Karl Mechtler, Shunya Uchida, Silvana Geleff, Due-Hee Kang, Richard J. Johnson and Dontscho Kerjaschki

JASN August 2003, 14 (8) 1981-1989; DOI: https://doi.org/10.1097/01.ASN.0000076078.50889.43

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Aldosterone Plays a Pivotal Role in the Pathogenesis of Thrombotic Microangiopathy in SHRSP
Praveen N. Chander, Ricardo Rocha, Jeffrey Ranaudo, Gagan Singh, Andrea Zuckerman and Charles T. Stier

JASN August 2003, 14 (8) 1990-1997; DOI: https://doi.org/10.1097/01.ASN.0000078960.15147.05

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Molecular Medicine, Genetics, and Development

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Inducible Podocyte-Specific Gene Expression in Transgenic Mice
Tetsuya Shigehara, Concepcion Zaragoza, Chagriya Kitiyakara, Hideko Takahashi, Huiyan Lu, Marcus Moeller, Lawrence B. Holzman and Jeffrey B. Kopp

JASN August 2003, 14 (8) 1998-2003; DOI: https://doi.org/10.1681/ASN.V1481998

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Milder Presentation of Recessive Polycystic Kidney Disease Requires Presence of Amino Acid Substitution Mutations
Laszlo Furu, Luiz F. Onuchic, Ali Gharavi, Xiaoying Hou, Ernie L. Esquivel, Yasuyuki Nagasawa, Carsten Bergmann, Jan Senderek, Ellis Avner, Klaus Zerres, Gregory G. Germino, Lisa M. Guay-Woodford and Stefan Somlo

JASN August 2003, 14 (8) 2004-2014; DOI: https://doi.org/10.1097/01.ASN.0000078805.87038.05

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Identification of a Common Risk Haplotype for Diabetic Nephropathy at the Protein Kinase C-β1 (PRKCB1) Gene Locus
Shin-ichi Araki, Daniel P.K. Ng, Bozena Krolewski, Lucjan Wyrwicz, John J. Rogus, Luis Canani, Yuichiro Makita, Masakazu Haneda, James H. Warram and Andrzej S. Krolewski

JASN August 2003, 14 (8) 2015-2024; DOI: https://doi.org/10.1097/01.ASN.0000077347.27669.5C

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Bioengineered Implantation of Megalin-Expressing Cells: A Potential Intracorporeal Therapeutic Model for Uremic Toxin Protein Clearance in Renal Failure
Akihiko Saito, Junichiro J. Kazama, Noriaki Iino, Kenji Cho, Nobuo Sato, Hajime Yamazaki, Yuko Oyama, Tetsuro Takeda, Robert A. Orlando, Fujio Shimizu, Yasuhiko Tabata and Fumitake Gejyo

JASN August 2003, 14 (8) 2025-2032; DOI: https://doi.org/10.1097/01.ASN.0000078804.98322.4A

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Distinct Molecular and Morphogenetic Properties of Mutations in the Human HNF1β Gene That Lead to Defective Kidney Development
Silvia Bohn, Heike Thomas, Gülüzar Turan, Sian Ellard, Coralie Bingham, Andrew T. Hattersley and Gerhart U. Ryffel

JASN August 2003, 14 (8) 2033-2041; DOI: https://doi.org/10.1097/01.ASN.0000078808.70309.C4

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Use of the Tetracycline System for Inducible Protein Synthesis in the Kidney
Anna Rachel Gallagher, Kai Schönig, Nelson Brown, Hermann Bujard and Ralph Witzgall

JASN August 2003, 14 (8) 2042-2051; DOI: https://doi.org/10.1097/01.ASN.0000079615.38843.4A

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Pathophysiology of Renal Disease

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Tissue Transglutaminase and the Progression of Human Renal Scarring
Timothy S. Johnson, Ahmed F. El-Koraie, N. James Skill, Nahed M. Baddour, A. Meguid El Nahas, Melvin Njloma, Ahmed G. Adam and Martin Griffin

JASN August 2003, 14 (8) 2052-2062; DOI: https://doi.org/10.1097/01.ASN.0000079614.63463.DD

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Expression of Podocyte-Associated Molecules in Acquired Human Kidney Diseases
Klaas Koop, Michael Eikmans, Hans J. Baelde, Hiroshi Kawachi, Emile de Heer, Leendert C. Paul and Jan A. Bruijn

JASN August 2003, 14 (8) 2063-2071; DOI: https://doi.org/10.1097/01.ASN.0000078803.53165.C9

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Protease-Activated Receptor-2 Expression in IgA Nephropathy: A Potential Role in the Pathogenesis of Interstitial Fibrosis
Giuseppe Grandaliano, Paola Pontrelli, Giuseppina Cerullo, Raffaella Monno, Elena Ranieri, Michele Ursi, Antonella Loverre, Loreto Gesualdo and Francesco P. Schena

JASN August 2003, 14 (8) 2072-2083; DOI: https://doi.org/10.1097/01.ASN.0000080315.37254.A1

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Clinical Nephrology

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Cholesterol and the Risk of Renal Dysfunction in Apparently Healthy Men
Elke S. Schaeffner, Tobias Kurth, Gary C. Curhan, Robert J. Glynn, Kathryn M. Rexrode, Colin Baigent, Julie E. Buring and J. Michael Gaziano

JASN August 2003, 14 (8) 2084-2091; DOI: https://doi.org/10.1681/ASN.V1482084

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Evidence that Clearance of Hepatitis C Virus RNA after α-Interferon Therapy in Dialysis Patients Is Sustained after Renal Transplantation
Nassim Kamar, Olivier Toupance, Matthias Buchler, Karine Sandres-Saune, Jacques Izopet, Dominique Durand and Lionel Rostaing

JASN August 2003, 14 (8) 2092-2098; DOI: https://doi.org/10.1097/01.ASN.0000079613.81511.3C

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The Spectrum of Systemic Involvement in Adults Presenting with Renal Lesion and Mitochondrial tRNA(Leu) Gene Mutation
Bruno Guéry, Gabriel Choukroun, Laure-Hélène Noël, Pierre Clavel, Agnès Rötig, Sophie Lebon, Pierre Rustin, Christine Bellané-Chantelot, Béatrice Mougenot, Jean-Pierre Grünfeld and Dominique Chauveau

JASN August 2003, 14 (8) 2099-2108; DOI: https://doi.org/10.1097/01.ASN.0000080180.51098.02

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Dialysis

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Inhibition of the Interaction of AGE–RAGE Prevents Hyperglycemia-Induced Fibrosis of the Peritoneal Membrane
An S. De Vriese, Allan Flyvbjerg, Siska Mortier, Ronald G. Tilton and Norbert H. Lameire

JASN August 2003, 14 (8) 2109-2118; DOI: https://doi.org/10.1681/ASN.V1482109

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Oral Sodium Bicarbonate for the Treatment of Metabolic Acidosis in Peritoneal Dialysis Patients: A Randomized Placebo-Control Trial
Cheuk-Chun Szeto, Teresa Yuk-Hwa Wong, Kai-Ming Chow, Chi-Bon Leung and Philip Kam-Tao Li

JASN August 2003, 14 (8) 2119-2126; DOI: https://doi.org/10.1097/01.ASN.0000080316.37254.7A

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Noninvasive Interventions to Decrease Hospitalization and Associated Costs for Pediatric Patients Receiving Hemodialysis
Stuart L. Goldstein, Carolyn M. Smith and Helen Currier

JASN August 2003, 14 (8) 2127-2131; DOI: https://doi.org/10.1097/01.ASN.0000076077.05508.7E

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Epidemiology and Outcomes

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Bias in Assessment of Health-Related Quality of Life in a Hemodialysis Population: A Comparison of Self-Administered and Interviewer-Administered Surveys in the HEMO Study
Mark Unruh, Guofen Yan, Milena Radeva, Ron D. Hays, Robert Benz, Nicolaos V. Athienites, John Kusek, Andrew S. Levey, Klemens B. Meyer and ; and the HEMO Study Group

JASN August 2003, 14 (8) 2132-2141; DOI: https://doi.org/10.1097/01.ASN.0000076076.88336.B1

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Transplantation

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Early Interstitial Accumulation of Collagen Type I Discriminates Chronic Rejection from Chronic Cyclosporine Nephrotoxicity
Rene C. Bakker, Klaas Koop, Yvo W. Sijpkens, Michael Eikmans, Ingeborg M. Bajema, Emile de Heer, Jan A. Bruijn and Leendert C. Paul

JASN August 2003, 14 (8) 2142-2149; DOI: https://doi.org/10.1097/01.ASN.0000077345.81206.00

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Islet Transplantation Is Associated with Improvement of Renal Function among Uremic Patients with Type I Diabetes Mellitus and Kidney Transplants
Paolo Fiorina, Franco Folli, Gianpaolo Zerbini, Paola Maffi, Chiara Gremizzi, Valerio Di Carlo, Carlo Socci, Federico Bertuzzi, Michael Kashgarian and Antonio Secchi

JASN August 2003, 14 (8) 2150-2158; DOI: https://doi.org/10.1097/01.ASN.0000077339.20759.A3

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Blood Pressure Evaluation among Older Living Kidney Donors
Stephen C. Textor, Sandra J. Taler, Timothy S. Larson, Mikel Prieto, Matthew Griffin, James Gloor, Scott Nyberg, Jorge Velosa, Thomas Schwab and Mark Stegall

JASN August 2003, 14 (8) 2159-2167; DOI: https://doi.org/10.1097/01.ASN.0000077346.92039.9C

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Allorecognition and Effector Pathways of Islet Allograft Rejection in Normal versus Nonobese Diabetic Mice
Leila Makhlouf, Akira Yamada, Toshiro Ito, Reza Abdi, Mohammed Javeed I. Ansari, Chau Q. Khuong, Henry J. Winn, Hugh Auchincloss and Mohamed H. Sayegh

JASN August 2003, 14 (8) 2168-2175; DOI: https://doi.org/10.1097/01.ASN.0000079041.15707.A9

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FRONTIERS IN NEPHROLOGY

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Acute Renal Failure: Directions for the Next Decade
Norman J. Siegel and Sudhir V. Shah

JASN August 2003, 14 (8) 2176-2177; DOI: https://doi.org/10.1097/01.ASN.0000079043.01987.34

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Acute Renal Failure Definitions and Classification: Time for Change?
Ravindra L. Mehta and Glenn M. Chertow

JASN August 2003, 14 (8) 2178-2187; DOI: https://doi.org/10.1097/01.ASN.0000079042.13465.1A

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Newly Developed Techniques to Study and Diagnose Acute Renal Failure
Pierre C. Dagher, Stefan Herget-Rosenthal, Stefan G. Ruehm, Sang-Kyung Jo, Robert A. Star, Rajiv Agarwal and Bruce A. Molitoris

JASN August 2003, 14 (8) 2188-2198; DOI: https://doi.org/10.1097/01.ASN.0000079790.91292.4A

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Recent Advances in the Pathophysiology of Ischemic Acute Renal Failure
Joseph V. Bonventre and Joel M. Weinberg

JASN August 2003, 14 (8) 2199-2210; DOI: https://doi.org/10.1097/01.ASN.0000079785.13922.F6

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EDITORIALS

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Cell Therapy: Leveraging Nature’s Therapeutic Potential
H. David Humes

JASN August 2003, 14 (8) 2211-2213; DOI: https://doi.org/10.1097/01.ASN.0000082692.79381.96

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Islet Transplants and Impact on Secondary Diabetic Complications: Does C-Peptide Protect the Kidney?
A. M. James Shapiro

JASN August 2003, 14 (8) 2214-2216; DOI: https://doi.org/10.1097/01.ASN.0000082923.60142.72

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ANNOUNCEMENTS

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JASN August 2003, 14 (8) 2217; DOI: https://doi.org/10.1681/ASN.V1482217

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Table of Contents

THIS MONTH'S HIGHLIGHTS

ASN NEWS

Cell and Transport Physiology

Hormones, Growth Factors, Cell Signaling, Cell Biology and Structure

Immunology and Pathology

Molecular Medicine, Genetics, and Development

Pathophysiology of Renal Disease

Clinical Nephrology

Dialysis

Epidemiology and Outcomes

Transplantation

FRONTIERS IN NEPHROLOGY

EDITORIALS

ANNOUNCEMENTS

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