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Basic Immunology and Pathology
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Experimental Autoimmune Anti–Glomerular Basement Membrane Glomerulonephritis: A Protective Role for IFN-γ

A. Richard Kitching, Amanda L. Turner, Timothy Semple, Ming Li, Kristy L. Edgtton, Gabrielle R. Wilson, Jennifer R. Timoshanko, Billy G. Hudson and Stephen R. Holdsworth
JASN July 2004, 15 (7) 1764-1774; DOI: https://doi.org/10.1097/01.ASN.0000128968.27705.5E
A. Richard Kitching
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Amanda L. Turner
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Timothy Semple
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Ming Li
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Kristy L. Edgtton
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Gabrielle R. Wilson
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Jennifer R. Timoshanko
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Billy G. Hudson
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Stephen R. Holdsworth
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Article Information

vol. 15 no. 7 1764-1774
DOI 
https://doi.org/10.1097/01.ASN.0000128968.27705.5E
PubMed 
15213264

Published By 
American Society of Nephrology
Print ISSN 
1046-6673
Online ISSN 
1533-3450
History 
  • Received for publication August 7, 2003
  • Accepted for publication March 31, 2004
  • Published online June 22, 2004.

Copyright & Usage 
© 2004 American Society of Nephrology

Author Information

  1. A. Richard Kitching*,
  2. Amanda L. Turner*,
  3. Timothy Semple*,
  4. Ming Li*,
  5. Kristy L. Edgtton*,
  6. Gabrielle R. Wilson*,
  7. Jennifer R. Timoshanko*,
  8. Billy G. Hudson† and
  9. Stephen R. Holdsworth*
  1. *Centre for Inflammatory Diseases, Monash University, Department of Medicine, Monash Medical Centre, Clayton, Victoria, Australia; and †Departments of Biochemistry and Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee
  1. Correspondence to Dr. A. Richard Kitching, Monash University Department of Medicine, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia. Phone: 61-3-9594-5520; Fax: 61-3-9594-6495; E-mail: richard.kitching{at}med.monash.edu.au
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Journal of the American Society of Nephrology: 15 (7)
Journal of the American Society of Nephrology
Vol. 15, Issue 7
1 Jul 2004
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Experimental Autoimmune Anti–Glomerular Basement Membrane Glomerulonephritis: A Protective Role for IFN-γ
A. Richard Kitching, Amanda L. Turner, Timothy Semple, Ming Li, Kristy L. Edgtton, Gabrielle R. Wilson, Jennifer R. Timoshanko, Billy G. Hudson, Stephen R. Holdsworth
JASN Jul 2004, 15 (7) 1764-1774; DOI: 10.1097/01.ASN.0000128968.27705.5E

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Experimental Autoimmune Anti–Glomerular Basement Membrane Glomerulonephritis: A Protective Role for IFN-γ
A. Richard Kitching, Amanda L. Turner, Timothy Semple, Ming Li, Kristy L. Edgtton, Gabrielle R. Wilson, Jennifer R. Timoshanko, Billy G. Hudson, Stephen R. Holdsworth
JASN Jul 2004, 15 (7) 1764-1774; DOI: 10.1097/01.ASN.0000128968.27705.5E
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More in this TOC Section

  • Inhibition of Toll-Like Receptor-7 (TLR-7) or TLR-7 plus TLR-9 Attenuates Glomerulonephritis and Lung Injury in Experimental Lupus
  • Toll-Like Receptor 4 Ligation on Intrinsic Renal Cells Contributes to the Induction of Antibody-Mediated Glomerulonephritis via CXCL1 and CXCL2
  • Overexpression of Interleukin-13 Induces Minimal-Change–Like Nephropathy in Rats
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  • A Bayesian approach for analysis of whole-genome bisulphite sequencing data identifies disease-associated changes in DNA methylation
  • A Bayesian Approach for Analysis of Whole-Genome Bisulfite Sequencing Data Identifies Disease-Associated Changes in DNA Methylation
  • MicroRNA-155 Drives TH17 Immune Response and Tissue Injury in Experimental Crescentic GN
  • Serum-Starved Adipose-Derived Stromal Cells Ameliorate Crescentic GN by Promoting Immunoregulatory Macrophages
  • The HLA-DRB1*15:01-Restricted Goodpasture's T Cell Epitope Induces GN
  • The Emergence of Th17 Cells as Effectors of Renal Injury
  • Alport Alloantibodies but Not Goodpasture Autoantibodies Induce Murine Glomerulonephritis: Protection by Quinary Crosslinks Locking Cryptic {alpha}3(IV) Collagen Autoepitopes In Vivo
  • Th1 and Th17 Cells Induce Proliferative Glomerulonephritis
  • IL-23, not IL-12, Directs Autoimmunity to the Goodpasture Antigen
  • The IL-23/Th17 Axis Contributes to Renal Injury in Experimental Glomerulonephritis
  • C1q enhances IFN-{gamma} production by antigen-specific T cells via the CD40 costimulatory pathway on dendritic cells
  • Renal Dendritic Cells Stimulate IL-10 Production and Attenuate Nephrotoxic Nephritis
  • CD100 Enhances Dendritic Cell and CD4+ Cell Activation Leading to Pathogenetic Humoral Responses and Immune Complex Glomerulonephritis
  • Anti-Neutrophil Cytoplasmic Antibodies and Effector CD4+ Cells Play Nonredundant Roles in Anti-Myeloperoxidase Crescentic Glomerulonephritis
  • Leukocyte Recruitment to the Inflamed Glomerulus: A Critical Role for Platelet-Derived P-Selectin in the Absence of Rolling
  • Granulocyte Macrophage Colony-Stimulating Factor Expression by Both Renal Parenchymal and Immune Cells Mediates Murine Crescentic Glomerulonephritis
  • IL-12p40 and IL-18 in Crescentic Glomerulonephritis: IL-12p40 is the Key Th1-Defining Cytokine Chain, Whereas IL-18 Promotes Local Inflammation and Leukocyte Recruitment
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