Skip to main content

Main menu

  • Home
  • Content
    • Published Ahead of Print
    • Current Issue
    • Article Collections
    • JASN Podcasts
    • Archives
    • Saved Searches
    • ASN Meeting Abstracts
  • Authors
    • Submit a Manuscript
    • Author Resources
  • Editorial Team
  • Subscriptions
  • More
    • About JASN
    • Alerts
    • Advertising
    • Editorial Fellowship Team
    • Feedback
    • Reprints
    • Impact Factor
    • Editorial Fellowship Application Process
  • ASN Kidney News
  • Other
    • CJASN
    • Kidney360
    • Kidney News Online
    • American Society of Nephrology

User menu

  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
American Society of Nephrology
  • Other
    • CJASN
    • Kidney360
    • Kidney News Online
    • American Society of Nephrology
  • Subscribe
  • My alerts
  • Log in
  • My Cart
Advertisement
American Society of Nephrology

Advanced Search

  • Home
  • Content
    • Published Ahead of Print
    • Current Issue
    • Article Collections
    • JASN Podcasts
    • Archives
    • Saved Searches
    • ASN Meeting Abstracts
  • Authors
    • Submit a Manuscript
    • Author Resources
  • Editorial Team
  • Subscriptions
  • More
    • About JASN
    • Alerts
    • Advertising
    • Editorial Fellowship Team
    • Feedback
    • Reprints
    • Impact Factor
    • Editorial Fellowship Application Process
  • ASN Kidney News
  • Follow JASN on Twitter
  • Visit ASN on Facebook
  • Follow JASN on RSS
  • Community Forum
Reviews
You have accessRestricted Access

Mouse Models of Diabetic Nephropathy

Matthew D. Breyer, Erwin Böttinger, Frank C. Brosius, Thomas M. Coffman, Raymond C. Harris, Charles W. Heilig, Kumar Sharma and ; for the AMDCC
JASN January 2005, 16 (1) 27-45; DOI: https://doi.org/10.1681/ASN.2004080648
Matthew D. Breyer
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Erwin Böttinger
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Frank C. Brosius III
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Thomas M. Coffman
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Raymond C. Harris
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Charles W. Heilig
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kumar Sharma
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data Supps
  • Info & Metrics
  • View PDF
Loading

Article Information

vol. 16 no. 1 27-45
DOI 
https://doi.org/10.1681/ASN.2004080648
PubMed 
15563560

Published By 
American Society of Nephrology
Print ISSN 
1046-6673
Online ISSN 
1533-3450
History 
  • Published online December 22, 2004.

Article Versions

  • Earlier version (November 24, 2004 - 06:55).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2005 American Society of Nephrology

Author Information

  1. Matthew D. Breyer*,
  2. Erwin Böttinger†,
  3. Frank C. Brosius III‡,
  4. Thomas M. Coffman§,
  5. Raymond C. Harris*,
  6. Charles W. Heilig‖,
  7. Kumar Sharma¶ and
  8. for the AMDCC
  1. *Vanderbilt University and VA Medical Center, Nashville, Tennessee; †Mount Sinai Medical School, New York, New York; ‡University of Michigan, Ann Arbor, Michigan; §Duke University and Durham VA Medical Centers, Durham, North Carolina; ‖Departments of Medicine and Cellular & Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; and ¶Dorrance Hamilton Research Laboratories, Thomas Jefferson University, Philadelphia, Pennsylvania
  1. Address correspondence to:
    Dr. Matthew D. Breyer, Division of Nephrology and Departments of Medicine and Molecular Physiology and Biophysics, Vanderbilt University Medical School, S3223 MCN, Division of Nephrology, Nashville, TN 37232. Phone: 615-343-9867; Fax: 615-343-4704; E-mail: matthew.breyer{at}vanderbilt.edu

Statistics from Altmetric.com

Article usage

Article usage: November 2004 to February 2021

AbstractFullPdf
Nov 200431032
Dec 2004167179229
Jan 2005119378223
Feb 200577295108
Mar 20059525574
Apr 200582170120
May 20057526756
Jun 20057421850
Jul 20057318363
Aug 20056018143
Sep 20055319557
Oct 20056426992
Nov 20058626257
Dec 20055315651
Jan 200626210122
Feb 200632206137
Mar 200650274190
Apr 200628210114
May 200649247142
Jun 200632190129
Jul 200623205146
Aug 200635207124
Sep 200636211147
Oct 20062515096
Nov 20062910991
Dec 2006229682
Jan 200729126105
Feb 20072711296
Mar 200751134109
Apr 200740146105
May 200737135123
Jun 2007288178
Jul 200730124112
Aug 200732127113
Sep 20073111699
Oct 200748125116
Nov 200749151103
Dec 2007318584
Jan 20082910991
Feb 2008448785
Mar 20085210186
Apr 20084211198
May 20085712086
Jun 200845127103
Jul 20085710989
Aug 20086811682
Sep 20088310385
Oct 200837142107
Nov 20084610484
Dec 20084511584
Jan 2009589299
Feb 2009509994
Mar 20096410381
Apr 20095580101
May 2009417998
Jun 2009348175
Jul 200972116113
Aug 20097087106
Sep 20094971106
Oct 2009567789
Nov 200970111118
Dec 20098710191
Jan 2010588390
Feb 20105610295
Mar 2010597387
Apr 2010608066
May 20108110089
Jun 20105457101
Jul 2010938693
Aug 201013210672
Sep 201086118106
Oct 201080113108
Nov 2010347797
Dec 201093377
Jan 201175086
Feb 20114237104
Mar 20112938106
Apr 20111335116
May 201107145
Jun 201101117
Jul 201105123
Aug 201102125
Sep 201103158
Oct 201105155
Nov 2011011157
Dec 2011014139
Jan 2012019124
Feb 2012014189
Mar 2012014197
Apr 20125049141
May 20123990156
Jun 20124443145
Jul 20125376181
Aug 20124256146
Sep 20124653174
Oct 20129153108
Nov 20128079109
Dec 2012975777
Jan 201310611598
Feb 2013798267
Mar 2013748467
Apr 20138210083
May 20138612587
Jun 20137211273
Jul 20135412173
Aug 2013516140
Sep 2013576151
Oct 20139012179
Nov 20138414375
Dec 2013506145
Jan 2014519445
Feb 20144613147
Mar 20147819182
Apr 20146716557
May 20146920467
Jun 20146317469
Jul 20148719277
Aug 20143515460
Sep 20146913976
Oct 20145414189
Nov 20143617358
Dec 20145814258
Jan 20155215768
Feb 20155519681
Mar 20157118876
Apr 20159920988
May 20155515573
Jun 20157317057
Jul 20159714455
Aug 20156123763
Sep 20155018081
Oct 20155619269
Nov 20155519874
Dec 20157217365
Jan 2016122217107
Feb 20167214758
Mar 20167319463
Apr 20166016951
May 20168916068
Jun 20165218576
Jul 20165617062
Aug 20164021074
Sep 20163713062
Oct 20163621691
Nov 20164215762
Dec 20167714652
Jan 20176128157
Feb 20175331372
Mar 20175717387
Apr 2017548155
May 20175818073
Jun 20175112042
Jul 20177415955
Aug 20175919662
Sep 20175828456
Oct 20176222453
Nov 20174420249
Dec 20173721757
Jan 20183318658
Feb 20183315752
Mar 20183513663
Apr 20183913062
May 20184716864
Jun 20183010631
Jul 20182611655
Aug 20183112770
Sep 20183511852
Oct 20182415855
Nov 20181520958
Dec 20182010439
Jan 20192916355
Feb 20192010958
Mar 20192612889
Apr 20191712055
May 20192810339
Jun 20191912153
Jul 20192814258
Aug 20191910249
Sep 20192612145
Oct 20192414654
Nov 20192012054
Dec 2019125856
Jan 20201810362
Feb 20201010168
Mar 2020199868
Apr 2020129475
May 2020119196
Jun 2020116488
Jul 20201567103
Aug 202095685
Sep 20201711293
Oct 20203012372
Nov 20202296109
Dec 20202110780
Jan 202130214170
Feb 20212511682

Cited By...

  • 380 Citations
  • Google Scholar
PreviousNext
Back to top

In this issue

Journal of the American Society of Nephrology: 16 (1)
Journal of the American Society of Nephrology
Vol. 16, Issue 1
1 Jan 2005
  • Table of Contents
  • Index by author
View Selected Citations (0)
Print
Download PDF
Sign up for Alerts
Email Article
Thank you for your help in sharing the high-quality science in JASN.
Enter multiple addresses on separate lines or separate them with commas.
Mouse Models of Diabetic Nephropathy
(Your Name) has sent you a message from American Society of Nephrology
(Your Name) thought you would like to see the American Society of Nephrology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Mouse Models of Diabetic Nephropathy
Matthew D. Breyer, Erwin Böttinger, Frank C. Brosius, Thomas M. Coffman, Raymond C. Harris, Charles W. Heilig, Kumar Sharma
JASN Jan 2005, 16 (1) 27-45; DOI: 10.1681/ASN.2004080648

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Request Permissions
Share
Mouse Models of Diabetic Nephropathy
Matthew D. Breyer, Erwin Böttinger, Frank C. Brosius, Thomas M. Coffman, Raymond C. Harris, Charles W. Heilig, Kumar Sharma
JASN Jan 2005, 16 (1) 27-45; DOI: 10.1681/ASN.2004080648
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like

Jump to section

  • Article
    • Abstract
    • Working Definition of DN
    • Characterization of DN in Mice
    • Assessment of Hyperglycemia in Mice
    • Assessment of Renal Function in Mice
    • Models of Type 1 Diabetes
    • Mouse Models of Type 2 Diabetes
    • Inbred Mice: Strain Dependence of DN
    • Monogenic Mutations and Transgenic Mice
    • Conclusions
    • Acknowledgments
    • References
  • Figures & Data Supps
  • Info & Metrics
  • View PDF

More in this TOC Section

  • Autoimmunity in Acute Poststreptococcal GN: A Neglected Aspect of the Disease
  • COVID-19 and AKI: Where Do We Stand?
  • Management of Obesity in Adults with CKD
Show more Reviews

Cited By...

  • Drug Testing for Residual Progression of Diabetic Kidney Disease in Mice Beyond Therapy with Metformin, Ramipril, and Empagliflozin
  • Systematic review and meta-analysis of mouse models of diabetes-associated ulcers
  • Paternal multigenerational exposure to an obesogenic diet drives epigenetic predisposition to metabolic disorders
  • Changes in excitability and ion channel expression in neurons of the major pelvic ganglion in female type II diabetic mice
  • Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function
  • Effects of insulin and the glucagon-like peptide 1 receptor agonist liraglutide on the kidney proteome in db/db mice
  • Glomerular Endothelial Mitochondrial Dysfunction Is Essential and Characteristic of Diabetic Kidney Disease Susceptibility
  • Comparison of Glomerular and Podocyte mRNA Profiles in Streptozotocin-Induced Diabetes
  • Low-Dose IL-17 Therapy Prevents and Reverses Diabetic Nephropathy, Metabolic Syndrome, and Associated Organ Fibrosis
  • Four-and-a-Half LIM Domains Protein 2 Is a Coactivator of Wnt Signaling in Diabetic Kidney Disease
  • Diabetes Induces Aberrant DNA Methylation in the Proximal Tubules of the Kidney
  • Albumin stimulates renal tubular inflammation through an HSP70-TLR4 axis in mice with early diabetic nephropathy
  • Vascular Endothelial Growth Factor-A165b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy
  • Renoprotective effects of combined SGLT2 and ACE inhibitor therapy in diabetic Dahl S rats
  • Progressive Renal Decline: The New Paradigm of Diabetic Nephropathy in Type 1 Diabetes
  • Endogenous Fructose Production and Fructokinase Activation Mediate Renal Injury in Diabetic Nephropathy
  • Loss of the Podocyte-Expressed Transcription Factor Tcf21/Pod1 Results in Podocyte Differentiation Defects and FSGS
  • CD73-Dependent Generation of Adenosine and Endothelial Adora2b Signaling Attenuate Diabetic Nephropathy
  • Knockdown of Glyoxalase 1 Mimics Diabetic Nephropathy in Nondiabetic Mice
  • Phlorizin Pretreatment Reduces Acute Renal Toxicity in a Mouse Model for Diabetic Nephropathy
  • A Role for the Endothelium in Vascular Calcification
  • Celecoxib modifies glomerular basement membrane, mesangium and podocytes in OVE26 mice, but ibuprofen is more detrimental
  • Direct Evidence for Intrarenal Chymase-Dependent Angiotensin II Formation on the Diabetic Renal Microvasculature
  • A Transcriptional Blueprint for Human and Murine Diabetic Kidney Disease
  • eNOS Deficiency Predisposes Podocytes to Injury in Diabetes
  • Intrarenal Dopamine Inhibits Progression of Diabetic Nephropathy
  • Transgenerational Glucose Intolerance With Igf2/H19 Epigenetic Alterations in Mouse Islet Induced by Intrauterine Hyperglycemia
  • Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice
  • Arginase-2 Mediates Diabetic Renal Injury
  • Knockout of Toll-Like Receptor-2 Attenuates Both the Proinflammatory State of Diabetes and Incipient Diabetic Nephropathy
  • Esculetin induced changes in Mmp13 and Bmp6 gene expression and histone H3 modifications attenuate development of glomerulosclerosis in diabetic rats
  • Thyroid hormone ameliorates diabetic nephropathy in a mouse model of type II diabetes
  • Activation of Vascular Bone Morphogenetic Protein Signaling in Diabetes Mellitus
  • The Protective Role of Smad7 in Diabetic Kidney Disease: Mechanism and Therapeutic Potential
  • Antiatherosclerotic and Renoprotective Effects of Ebselen in the Diabetic Apolipoprotein E/GPx1-Double Knockout Mouse
  • BTBR Ob/Ob Mutant Mice Model Progressive Diabetic Nephropathy
  • Inhibition or Deletion of Soluble Epoxide Hydrolase Prevents Hyperglycemia, Promotes Insulin Secretion, and Reduces Islet Apoptosis
  • Deletion of the Receptor for Advanced Glycation End Products Reduces Glomerulosclerosis and Preserves Renal Function in the Diabetic OVE26 Mouse
  • Mouse Models of Diabetic Nephropathy
  • Vasohibin-1, a Negative Feedback Regulator of Angiogenesis, Ameliorates Renal Alterations in a Mouse Model of Diabetic Nephropathy
  • Effect of the Monocyte Chemoattractant Protein-1/CC Chemokine Receptor 2 System on Nephrin Expression in Streptozotocin-Treated Mice and Human Cultured Podocytes
  • Activation of the Succinate Receptor GPR91 in Macula Densa Cells Causes Renin Release
  • The Use of Animal Models in the Study of Diabetes Mellitus
  • Enhanced Expression of Janus Kinase-Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy
  • Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: Blockade of compensatory renin increase
  • Overexpression of Calmodulin in Pancreatic {beta} Cells Induces Diabetic Nephropathy
  • From Fibrosis to Sclerosis: Mechanisms of Glomerulosclerosis in Diabetic Nephropathy
  • Long-term hyperglucagonaemia induces early metabolic and renal phenotypes of Type 2 diabetes in mice
  • Overexpression of Angiotensinogen Increases Tubular Apoptosis in Diabetes
  • Can rodent models of diabetic kidney disease clarify the significance of early hyperfiltration?: recognizing clinical and experimental uncertainties
  • Thrombospondin-1 Is an Endogenous Activator of TGF-{beta} in Experimental Diabetic Nephropathy In Vivo
  • L-Carnosine, a Substrate of Carnosinase-1, Influences Glucose Metabolism
  • The Vascular Ectonucleotidase ENTPD1 Is a Novel Renoprotective Factor in Diabetic Nephropathy
  • Targeting glucagon receptor signalling in treating metabolic syndrome and renal injury in Type 2 diabetes: theory versus promise
  • Renal Fibrosis and Glomerulosclerosis in a New Mouse Model of Diabetic Nephropathy and Its Regression by Bone Morphogenic Protein-7 and Advanced Glycation End Product Inhibitors
  • Interstitial Vascular Rarefaction and Reduced VEGF-A Expression in Human Diabetic Nephropathy
  • Recipes for Creating Animal Models of Diabetic Cardiovascular Disease
  • Diabetic Endothelial Nitric Oxide Synthase Knockout Mice Develop Advanced Diabetic Nephropathy
  • A Sensitized Screen of N-ethyl-N-nitrosourea-Mutagenized Mice Identifies Dominant Mutants Predisposed to Diabetic Nephropathy
  • Poly(ADP-Ribose) Polymerase Inhibitors Ameliorate Nephropathy of Type 2 Diabetic Leprdb/db Mice
  • Endothelial Nitric Oxide Synthase Deficiency Produces Accelerated Nephropathy in Diabetic Mice
  • Heme Oxygenase-2 Deficiency Contributes to Diabetes-Mediated Increase in Superoxide Anion and Renal Dysfunction
  • Frontiers in Diabetic Nephropathy: Can We Predict Who Will Get Sick?
  • Leukocyte Recruitment and Vascular Injury in Diabetic Nephropathy
  • Glucose-Induced Reactive Oxygen Species Cause Apoptosis of Podocytes and Podocyte Depletion at the Onset of Diabetic Nephropathy
  • Activation of G{alpha}q-Coupled Signaling Pathways in Glomerular Podocytes Promotes Renal Injury
  • Antiangiogenic Endostatin Peptide Ameliorates Renal Alterations in the Early Stage of a Type 1 Diabetic Nephropathy Model
  • Characterization of Susceptibility of Inbred Mouse Strains to Diabetic Nephropathy
  • Accelerated Glucose Intolerance, Nephropathy, and Atherosclerosis in Prostaglandin D2 Synthase Knock-out Mice
  • Google Scholar

Similar Articles

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Articles

  • Current Issue
  • Early Access
  • Subject Collections
  • Article Archive
  • ASN Annual Meeting Abstracts

Information for Authors

  • Submit a Manuscript
  • Author Resources
  • Editorial Fellowship Program
  • ASN Journal Policies
  • Reuse/Reprint Policy

About

  • JASN
  • ASN
  • ASN Journals
  • ASN Kidney News

Journal Information

  • About JASN
  • JASN Email Alerts
  • JASN Key Impact Information
  • JASN Podcasts
  • JASN RSS Feeds
  • Editorial Board

More Information

  • Advertise
  • ASN Podcasts
  • ASN Publications
  • Become an ASN Member
  • Feedback
  • Follow on Twitter
  • Password/Email Address Changes
  • Subscribe

© 2021 American Society of Nephrology

Print ISSN - 1046-6673 Online ISSN - 1533-3450

Powered by HighWire