Journal of the American Society of Nephrology: 18 (3)

March 2007; Volume 18,Issue 3

ASN News

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ASN News
JASN March 2007, 18 (3) A27-A30; DOI: https://doi.org/10.1681/ASN.2007010102

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This Month's Highlights

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This Month’s Highlights
JASN March 2007, 18 (3) 661-662; DOI: https://doi.org/10.1681/ASN.2007010105

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Nephrology beyond JASN

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Endothelial Cell Dysfunction—Can One Outsmart Oxidative Stress by Direct Interaction with the Pathological Oxidized or Heme-Free Soluble Guanyl-Cyclase?
J.-P. Stasch, P.M. Schmidt, P.I. Nedvetsky, T.Y. Arun Nedvetskaya, H.S. Kumar, S. Meurer, M. Deile, A. Taye, A. Knorr, H. Lapp, H. Müller, Y. Turgay, C. Rothkegel, A. Tersteegen, B. Kemp-Harper, W. Müller-Esterl and H. Schmidt

JASN March 2007, 18 (3) 663-669; DOI: https://doi.org/10.1681/ASN.2007010103

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Editorials

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Critical Role of Urea in the Urine-Concentrating Mechanism
Jeff M. Sands

JASN March 2007, 18 (3) 670-671; DOI: https://doi.org/10.1681/ASN.2006121314

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Breaking Down the Barrier: Evidence against a Role for Heparan Sulfate in Glomerular Permselectivity
Scott J. Harvey and Jeffrey H. Miner

JASN March 2007, 18 (3) 672-674; DOI: https://doi.org/10.1681/ASN.2007010086

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Uremic Retention Solutes: The Free and the Bound
Thomas Depner and Jonathan Himmelfarb

JASN March 2007, 18 (3) 675-676; DOI: https://doi.org/10.1681/ASN.2007010071

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Special Tribute

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In Memoriam: Fokke Johannes van der Woude 1953–2006
JASN March 2007, 18 (3) 677-678; DOI: https://doi.org/10.1681/ASN.2006121381

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Review

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Urea and Renal Function in the 21st Century: Insights from Knockout Mice
Robert A. Fenton and Mark A. Knepper

JASN March 2007, 18 (3) 679-688; DOI: https://doi.org/10.1681/ASN.2006101108

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Cell Biology

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Expression and Subcellular Distribution of Novel Glomerulus-Associated Proteins Dendrin, Ehd3, Sh2d4a, Plekhh2, and 2310066E14Rik
Jaakko Patrakka, Zhijie Xiao, Masatoshi Nukui, Minoru Takemoto, Liqun He, Asmundur Oddsson, Ljubica Perisic, Anne Kaukinen, Cristina Al-Khalili Szigyarto, Mathias Uhlén, Hannu Jalanko, Christer Betsholtz and Karl Tryggvason

JASN March 2007, 18 (3) 689-697; DOI: https://doi.org/10.1681/ASN.2006060675

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Distribution of α-Galactosidase A in Normal Human Kidney and Renal Accumulation and Distribution of Recombinant α-Galactosidase A in Fabry Mice
Erik I. Christensen, Qun Zhou, Søren S. Sørensen, Åse K. Rasmussen, Christian Jacobsen, Ulla Feldt-Rasmussen and Rikke Nielsen

JASN March 2007, 18 (3) 698-706; DOI: https://doi.org/10.1681/ASN.2006080822

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Genetics and Development

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Cystic Fibrosis Is Associated with a Defect in Apical Receptor–Mediated Endocytosis in Mouse and Human Kidney
François Jouret, Alfred Bernard, Cédric Hermans, Geneviève Dom, Sara Terryn, Teresinha Leal, Patrick Lebecque, Jean-Jacques Cassiman, Bob J. Scholte, Hugo R. de Jonge, Pierre J. Courtoy and Olivier Devuyst

JASN March 2007, 18 (3) 707-718; DOI: https://doi.org/10.1681/ASN.2006030269

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Impaired Glomerular Maturation and Lack of VEGF165b in Denys-Drash Syndrome
Valérie Anne Schumacher, Stefanie Jeruschke, Frank Eitner, Jan Ulrich Becker, Gerald Pitschke, Yasemin Ince, Jeffrey H. Miner, Ivo Leuschner, Rainer Engers, Anne Schulze Everding, Monika Bulla and Brigitte Royer-Pokora

JASN March 2007, 18 (3) 719-729; DOI: https://doi.org/10.1681/ASN.2006020124

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Hemodynamics and Vascular Regulation

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Lack of Endothelial Nitric Oxide Synthase Promotes Endothelin-Induced Hypertension: Lessons from Endothelin-1 Transgenic/Endothelial Nitric Oxide Synthase Knockout Mice
Thomas Quaschning, Florian Voss, Katharina Relle, Philipp Kalk, Nicolas Vignon-Zellweger, Thiemo Pfab, Christian Bauer, Franziska Theilig, Sebastian Bachmann, Annette Kraemer-Guth, Christoph Wanner, Franz Theuring, Jan Galle and Berthold Hocher

JASN March 2007, 18 (3) 730-740; DOI: https://doi.org/10.1681/ASN.2006050541

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Insulin Induces Renal Vasodilation, Increases Plasma Renin Activity, and Sensitizes the Renal Vasculature to Angiotensin Receptor Blockade in Healthy Subjects
Todd S. Perlstein, Marie Gerhard-Herman, Norman K. Hollenberg, Gordon H. Williams and Abraham Thomas

JASN March 2007, 18 (3) 944-951; DOI: https://doi.org/10.1681/ASN.2006091026

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Chronic Kidney Disease

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Role of Nitric Oxide–Producing and –Degrading Pathways in Coronary Endothelial Dysfunction in Chronic Kidney Disease
Satoru Tatematsu, Shu Wakino, Takeshi Kanda, Koichiro Homma, Kyoko Yoshioka, Kazuhiro Hasegawa, Naoki Sugano, Masumi Kimoto, Takao Saruta and Koichi Hayashi

JASN March 2007, 18 (3) 741-749; DOI: https://doi.org/10.1681/ASN.2006040367

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Long-Term, High-Dosage Candesartan Suppresses Inflammation and Injury in Chronic Kidney Disease: Nonhemodynamic Renal Protection
Chen Yu, Rujun Gong, Abdlla Rifai, Evelyn M. Tolbert and Lance D. Dworkin

JASN March 2007, 18 (3) 750-759; DOI: https://doi.org/10.1681/ASN.2006070770

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Association between Multidisciplinary Care and Survival for Elderly Patients with Chronic Kidney Disease
Brenda R. Hemmelgarn, Braden J. Manns, Jianguo Zhang, Marcello Tonelli, Scott Klarenbach, Michael Walsh, Bruce F. Culleton and ; for the Alberta Kidney Disease Network

JASN March 2007, 18 (3) 993-999; DOI: https://doi.org/10.1681/ASN.2006080860

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Basic Immunology and Pathology

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Endogenous Myeloperoxidase Promotes Neutrophil-Mediated Renal Injury, but Attenuates T Cell Immunity Inducing Crescentic Glomerulonephritis
Dragana Odobasic, A. Richard Kitching, Timothy J. Semple and Stephen R. Holdsworth

JASN March 2007, 18 (3) 760-770; DOI: https://doi.org/10.1681/ASN.2006040375

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Presentation of the Goodpasture Autoantigen Requires Proteolytic Unlocking Steps That Destroy Prominent T Cell Epitopes
Juan Zou, Lorna Henderson, Vicky Thomas, Patricia Swan, A. Neil Turner and Richard. G. Phelps

JASN March 2007, 18 (3) 771-779; DOI: https://doi.org/10.1681/ASN.2006091056

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DEC-205–Mediated Internalization of HIV-1 Results in the Establishment of Silent Infection in Renal Tubular Cells
Ikusuke Hatsukari, Priyanka Singh, Naoko Hitosugi, Davorka Messmer, Elsa Valderrama, Saul Teichberg, Wayne Chaung, Eleanore Gross, Helena Schmidtmayerova and Pravin C. Singhal

JASN March 2007, 18 (3) 780-787; DOI: https://doi.org/10.1681/ASN.2006121307

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Thrombospondin 2 Functions as an Endogenous Regulator of Angiogenesis and Inflammation in Experimental Glomerulonephritis in Mice
Christoph Daniel, Kerstin Amann, Bernd Hohenstein, Paul Bornstein and Christian Hugo

JASN March 2007, 18 (3) 788-798; DOI: https://doi.org/10.1681/ASN.2006080873

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Active Focal Segmental Glomerulosclerosis Is Associated with Massive Oxidation of Plasma Albumin
Luca Musante, Giovanni Candiano, Andrea Petretto, Maurizio Bruschi, Nazzareno Dimasi, Gianluca Caridi, Barbara Pavone, Piero Del Boccio, Monica Galliano, Andrea Urbani, Francesco Scolari, Flavio Vincenti and Gian Marco Ghiggeri

JASN March 2007, 18 (3) 799-810; DOI: https://doi.org/10.1681/ASN.2006090965

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Unrestricted C3 Activation Occurs in Crry-Deficient Kidneys and Rapidly Leads to Chronic Renal Failure
Lihua Bao, Ying Wang, Anthony Chang, Andrew W. Minto, Jian Zhou, Hong Kang, Mark Haas and Richard J. Quigg

JASN March 2007, 18 (3) 811-822; DOI: https://doi.org/10.1681/ASN.2006101176

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Pathophysiology of Renal Disease and Progression

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In Vivo Degradation of Heparan Sulfates in the Glomerular Basement Membrane Does Not Result in Proteinuria
Tessa J.M. Wijnhoven, Joost F.M. Lensen, Ronnie G.P. Wismans, Mohammed Lamrani, Leo A.H. Monnens, Ron A. Wevers, Angelique L.W.M.M. Rops, Johan van der Vlag, Jo H.M. Berden, Lambert P.W.J. van den Heuvel and Toin H. van Kuppevelt

JASN March 2007, 18 (3) 823-832; DOI: https://doi.org/10.1681/ASN.2006070692

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Protective Role of Ecto-5′-Nucleotidase (CD73) in Renal Ischemia
Almut Grenz, Hua Zhang, Tobias Eckle, Michel Mittelbronn, Manfred Wehrmann, Christoph Köhle, Doris Kloor, Linda F. Thompson, Hartmut Osswald and Holger K. Eltzschig

JASN March 2007, 18 (3) 833-845; DOI: https://doi.org/10.1681/ASN.2006101141

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Plasmin(ogen) Promotes Renal Interstitial Fibrosis by Promoting Epithelial-to-Mesenchymal Transition: Role of Plasmin-Activated Signals
Guoqiang Zhang, Kelly A. Kernan, Sarah J. Collins, Xiaohe Cai, Jesús M. López-Guisa, Jay L. Degen, Yigal Shvil and Allison A. Eddy

JASN March 2007, 18 (3) 846-859; DOI: https://doi.org/10.1681/ASN.2006080886

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Role of Protein C in Renal Dysfunction after Polymicrobial Sepsis
Akanksha Gupta, David T. Berg, Bruce Gerlitz, Ganesh R. Sharma, Samreen Syed, Mark A. Richardson, George Sandusky, Josef G. Heuer, Elizabeth J. Galbreath and Brian W. Grinnell

JASN March 2007, 18 (3) 860-867; DOI: https://doi.org/10.1681/ASN.2006101167

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Basic Dialysis

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Increasing the Clearance of Protein-Bound Solutes by Addition of a Sorbent to the Dialysate
Timothy W. Meyer, John W.T. Peattie, Jared D. Miller, Diana C. Dinh, Natalie S. Recht, Jason L. Walther and Thomas H. Hostetter

JASN March 2007, 18 (3) 868-874; DOI: https://doi.org/10.1681/ASN.2006080863

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Disease of the Month

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Metabolic Bone Disease in Chronic Kidney Disease
Kevin J. Martin and Esther A. González

JASN March 2007, 18 (3) 875-885; DOI: https://doi.org/10.1681/ASN.2006070771

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Clinical Nephrology

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Efficient Removal of Immunoglobulin Free Light Chains by Hemodialysis for Multiple Myeloma: In Vitro and In Vivo Studies
Colin A. Hutchison, Paul Cockwell, Steven Reid, Katie Chandler, Graham P. Mead, John Harrison, John Hattersley, Neil D. Evans, Mike J. Chappell, Mark Cook, Hermann Goehl, Markus Storr and Arthur R. Bradwell

JASN March 2007, 18 (3) 886-895; DOI: https://doi.org/10.1681/ASN.2006080821

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Glycated Albumin Is a Better Glycemic Indicator than Glycated Hemoglobin Values in Hemodialysis Patients with Diabetes: Effect of Anemia and Erythropoietin Injection
Masaaki Inaba, Senji Okuno, Yasuro Kumeda, Shinsuke Yamada, Yasuo Imanishi, Tsutomu Tabata, Mikio Okamura, Shigeki Okada, Tomoyuki Yamakawa, Eiji Ishimura, Yoshiki Nishizawa and and the Osaka CKD Expert Research Group

JASN March 2007, 18 (3) 896-903; DOI: https://doi.org/10.1681/ASN.2006070772

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Urinary N-Acetyl-β-(D)-Glucosaminidase Activity and Kidney Injury Molecule-1 Level Are Associated with Adverse Outcomes in Acute Renal Failure
Orfeas Liangos, Mary C. Perianayagam, Vishal S. Vaidya, Won K. Han, Ron Wald, Hocine Tighiouart, Robert W. MacKinnon, Lijun Li, Vaidyanathapuram S. Balakrishnan, Brian J.G. Pereira, Joseph V. Bonventre and Bertrand L. Jaber

JASN March 2007, 18 (3) 904-912; DOI: https://doi.org/10.1681/ASN.2006030221

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Urine Biomarkers Predict the Cause of Glomerular Disease
Sanju A. Varghese, T. Brian Powell, Milos N. Budisavljevic, Jim C. Oates, John R. Raymond, Jonas S. Almeida and John M. Arthur

JASN March 2007, 18 (3) 913-922; DOI: https://doi.org/10.1681/ASN.2006070767

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Human Genetics

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Anomalies of the TCF2 Gene Are the Main Cause of Fetal Bilateral Hyperechogenic Kidneys
Stéphane Decramer, Olivier Parant, Sandrine Beaufils, Séverine Clauin, Cécile Guillou, Sylvie Kessler, Jacqueline Aziza, Flavio Bandin, Joost P. Schanstra and Christine Bellanné-Chantelot

JASN March 2007, 18 (3) 923-933; DOI: https://doi.org/10.1681/ASN.2006091057

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Identification of a Forskolin-Like Molecule in Human Renal Cysts
William C. Putnam, Sarah M. Swenson, Gail A. Reif, Darren P. Wallace, George M. Helmkamp and Jared J. Grantham

JASN March 2007, 18 (3) 934-943; DOI: https://doi.org/10.1681/ASN.2006111218

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Epidemiology and Outcomes

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Infection-Related Hospitalization Rates in Pediatric versus Adult Patients with End-Stage Renal Disease in the United States
Blanche M. Chavers, Craig A. Solid, David T. Gilbertson and Allan J. Collins

JASN March 2007, 18 (3) 952-959; DOI: https://doi.org/10.1681/ASN.2006040406

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Lowest Systolic Blood Pressure Is Associated with Stroke in Stages 3 to 4 Chronic Kidney Disease
Daniel E. Weiner, Hocine Tighiouart, Andrew S. Levey, Essam Elsayed, John L. Griffith, Deeb N. Salem and Mark J. Sarnak

JASN March 2007, 18 (3) 960-966; DOI: https://doi.org/10.1681/ASN.2006080858

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Association between Body Mass Index and Mortality Is Similar in the Hemodialysis Population and the General Population at High Age and Equal Duration of Follow-Up
Renée de Mutsert, Marieke B. Snijder, Femke van der Sman-de Beer, Jacob C. Seidell, Elisabeth W. Boeschoten, Raymond T. Krediet, Jacqueline M. Dekker, Jan P. Vandenbroucke, Friedo W. Dekker and ; for the Netherlands Cooperative Study on the Adequacy of Dialysis-2 (NECOSAD) Study Group

JASN March 2007, 18 (3) 967-974; DOI: https://doi.org/10.1681/ASN.2006091050

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Clinical Dialysis

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Ferric Gluconate Is Highly Efficacious in Anemic Hemodialysis Patients with High Serum Ferritin and Low Transferrin Saturation: Results of the Dialysis Patients’ Response to IV Iron with Elevated Ferritin (DRIVE) Study
Daniel W. Coyne, Toros Kapoian, Wadi Suki, Ajay K. Singh, John E. Moran, Naomi V. Dahl, Adel R. Rizkala and the DRIVE Study Group

JASN March 2007, 18 (3) 975-984; DOI: https://doi.org/10.1681/ASN.2006091034

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Far-Infrared Therapy: A Novel Treatment to Improve Access Blood Flow and Unassisted Patency of Arteriovenous Fistula in Hemodialysis Patients
Chih-Ching Lin, Chao-Fu Chang, Ming-Yu Lai, Tzen-Wen Chen, Pui-Ching Lee and Wu-Chang Yang

JASN March 2007, 18 (3) 985-992; DOI: https://doi.org/10.1681/ASN.2006050534

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Clinical Transplantation

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Outcome of Multipair Donor Kidney Exchange by a Web-Based Algorithm
Beom Seok Kim, Yu Seun Kim, Soon Il Kim, Myoung Soo Kim, Ho Yung Lee, Yong-Lim Kim, Chan Duck Kim, Chul Woo Yang, Bum Soon Choi, Duck Jong Han, Yon Su Kim, Sung Joo Kim, Ha-Young Oh and Dae Joong Kim

JASN March 2007, 18 (3) 1000-1006; DOI: https://doi.org/10.1681/ASN.2006101071

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Regulatory T Cells and T Cell Depletion: Role of Immunosuppressive Drugs
Marina Noris, Federica Casiraghi, Marta Todeschini, Paolo Cravedi, Daniela Cugini, Giuseppe Monteferrante, Sistiana Aiello, Linda Cassis, Eliana Gotti, Flavio Gaspari, Dario Cattaneo, Norberto Perico and Giuseppe Remuzzi

JASN March 2007, 18 (3) 1007-1018; DOI: https://doi.org/10.1681/ASN.2006101143

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Announcements

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Announcements
JASN March 2007, 18 (3) 1019;

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Table of Contents

ASN News

This Month's Highlights

Nephrology beyond JASN

Editorials

Special Tribute

Review

Cell Biology

Genetics and Development

Hemodynamics and Vascular Regulation

Chronic Kidney Disease

Basic Immunology and Pathology

Pathophysiology of Renal Disease and Progression

Basic Dialysis

Disease of the Month

Clinical Nephrology

Human Genetics

Epidemiology and Outcomes

Clinical Dialysis

Clinical Transplantation

Announcements

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