Article Figures & Data
Figures
- Figure 1.
Recipient native eGFR at PKT. (A) Distributions of eGFR in 1995, 2002, and 2009 are illustrated by kernel density plots. (B) Distribution of eGFR categories among PKT recipients, 1995–2009.
- Figure 2.
Kaplan-Meier estimates of (A) patient survival, and (B) death-censored graft survival in PKT recipients, by pretransplant eGFR.
Tables
Characteristic Adjusted Relative Rate (95% CI) P Value Transplant year 1.12 (1.11–1.13) <0.001 Age (per decade, <50 yr)* 0.91 (0.87–0.95) <0.001 Age (per decade, ≥50 yr)* 1.04 (0.98–1.09) 0.2 Female gender 0.87 (0.82–0.93) <0.001 Race Caucasian reference African American 0.90 (0.81–1.00) 0.04 other 0.78 (0.70–0.86) <0.001 Cause of ESRD glomerulonephritis reference diabetes 1.52 (1.39–1.66) <0.001 polycystic kidney disease 0.77 (0.70–0.86) <0.001 hypertension 1.07 (0.97–1.19) 0.2 renovascular 0.96 (0.77–1.19) 0.7 congenital 0.94 (0.76–1.17) 0.6 tubulointerstitial 1.30 (1.15–1.46) <0.001 neoplasm 1.02 (0.53–1.96) 0.9 other 1.13 (1.01–1.27) 0.04 Poor functional status** 1.14 (1.04–1.25) 0.006 Blood type A reference B 0.86 (0.77–0.95) 0.004 AB 1.07 (0.94–1.21) 0.3 O 0.95 (0.89–1.01) 0.1 Private insurance 1.00 (0.93–1.08) 0.9 Living donor 1.03 (0.97–1.11) 0.3 Donor age 1.00 (1.00–1.00) 0.6 * Age was modeled as a spline with a knot at 50 yr after bivariate exploration with the outcome.
** Poor functional status reflected any impairment in functional status at transplantation or registration. The 4.5% of recipients missing functional status were assumed to be 100% functional.
eGFR at PKT Adjusted HR of Death Adjusted HR of Death-Censored Graft Loss eGFR <10 reference reference eGFR 10–15 1.10 (95% CI 0.99–1.21, P = 0.07) 0.97 (95% CI 0.88–1.08, P = 0.6) eGFR 15–20 1.16 (95% CI 1.00–1.34, P = 0.05) 0.95 (95% CI 0.81–1.11, P = 0.5) eGFR ≥20 1.12 (95% CI 0.93–1.34, P = 0.2) 0.94 (95% CI 0.77–1.15, P = 0.5) *Propensity score-adjusted.
BRIEF COMMUNICATION Trends in the Timing of Preemptive Kidney Transplantation
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