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Mechanistic Insights into Vascular Calcification in CKD

Rukshana Shroff, David A. Long and Catherine Shanahan
JASN February 2013, 24 (2) 179-189; DOI: https://doi.org/10.1681/ASN.2011121191
Rukshana Shroff
*Nephro-Urology Unit, Great Ormond Street Hospital for Children and University College London Institute of Child Health, London, United Kingdom; and
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David A. Long
*Nephro-Urology Unit, Great Ormond Street Hospital for Children and University College London Institute of Child Health, London, United Kingdom; and
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Catherine Shanahan
†BHF Centre, Division of Cardiovascular Medicine, Kings College London, London, United Kingdom
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Article Information

vol. 24 no. 2 179-189
DOI 
https://doi.org/10.1681/ASN.2011121191
PubMed 
23138485

Published By 
American Society of Nephrology
Print ISSN 
1046-6673
Online ISSN 
1533-3450
History 
  • Published online January 31, 2013.

Article Versions

  • Earlier version (November 8, 2012 - 09:56).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2013 by the American Society of Nephrology

Author Information

  1. Rukshana Shroff*,
  2. David A. Long* and
  3. Catherine Shanahan†
  1. *Nephro-Urology Unit, Great Ormond Street Hospital for Children and University College London Institute of Child Health, London, United Kingdom; and
  2. †BHF Centre, Division of Cardiovascular Medicine, Kings College London, London, United Kingdom
  1. Correspondence:
    Dr. Rukshana Shroff, Nephro-Urology Unit, Great Ormond Street Hospital for Children and University College London Institute of Child Health, London WC1N 3JH, UK. Email: Rukshana.Shroff{at}gosh.nhs.uk
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Journal of the American Society of Nephrology: 24 (2)
Journal of the American Society of Nephrology
Vol. 24, Issue 2
February 2013
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Mechanistic Insights into Vascular Calcification in CKD
Rukshana Shroff, David A. Long, Catherine Shanahan
JASN Feb 2013, 24 (2) 179-189; DOI: 10.1681/ASN.2011121191

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Mechanistic Insights into Vascular Calcification in CKD
Rukshana Shroff, David A. Long, Catherine Shanahan
JASN Feb 2013, 24 (2) 179-189; DOI: 10.1681/ASN.2011121191
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  • Article
    • Abstract
    • Sites of Calcification and Their Clinical Consequences
    • Model Systems to Study Vascular Calcification
    • Vascular Calcification Is Similar to Physiologic Bone Ossification
    • Cellular Mechanisms of Calcium- and Phosphate-Induced Calcification
    • Accelerated Calcification in Vessels from Children on Dialysis: Clinicopathological Correlations
    • Emerging Concepts in VSMC Calcification
    • Clinical Perspective
    • Future Directions
    • Disclosures
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data Supps
  • Info & Metrics
  • View PDF

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  • Targeting Vascular Calcification in Chronic Kidney Disease
  • Hyperhomocysteinemia induces vascular calcification by activating the transcription factor RUNX2 via Krüppel-like factor 4 up-regulation in mice
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  • Effects of Hemodiafiltration versus Conventional Hemodialysis in Children with ESKD: The HDF, Heart and Height Study
  • Abdominal Aortic Calcifications Predict Survival in Peritoneal Dialysis Patients
  • Zinc Inhibits Phosphate-Induced Vascular Calcification through TNFAIP3-Mediated Suppression of NF-{kappa}B
  • Chronic Kidney Disease Circulating Calciprotein Particles and Extracellular Vesicles Promote Vascular Calcification: A Role for GRP (Gla-Rich Protein)
  • Anion Gap as a Determinant of Ionized Fraction of Divalent Cations in Hemodialysis Patients
  • Signaling of Serum Amyloid A Through Receptor for Advanced Glycation End Products as a Possible Mechanism for Uremia-Related Atherosclerosis
  • Uremic Toxicity of Advanced Glycation End Products in CKD
  • NH4Cl Treatment Prevents Tissue Calcification in Klotho Deficiency
  • Vascular Calcification in Predialysis CKD: Common and Deadly
  • Gla-Rich Protein Acts as a Calcification Inhibitor in the Human Cardiovascular System
  • HDL in Children with CKD Promotes Endothelial Dysfunction and an Abnormal Vascular Phenotype
  • Dietary L-Lysine Prevents Arterial Calcification in Adenine-Induced Uremic Rats
  • Associations of FGF-23 and sKlotho with Cardiovascular Outcomes among Patients with CKD Stages 2-4
  • Coronary Artery Calcification: Pathogenesis and Prognostic Implications
  • Serum Calcification Propensity Predicts All-Cause Mortality in Predialysis CKD
  • Single FGF-23 Measurement and Time-Averaged Plasma Phosphate Levels in Hemodialysis Patients
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