Skip to main content

Main menu

  • Home
  • Content
    • Published Ahead of Print
    • Current Issue
    • Subject Collections
    • JASN Podcasts
    • Archives
    • Saved Searches
    • ASN Meeting Abstracts
  • Authors
    • Submit a Manuscript
    • Author Resources
  • Editorial Team
  • Subscriptions
  • More
    • About JASN
    • Alerts
    • Advertising
    • Editorial Fellowship Program
    • Feedback
    • Reprints
    • Impact Factor
  • ASN Kidney News
  • Other
    • CJASN
    • Kidney360
    • Kidney News Online
    • American Society of Nephrology

User menu

  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
American Society of Nephrology
  • Other
    • CJASN
    • Kidney360
    • Kidney News Online
    • American Society of Nephrology
  • Subscribe
  • My alerts
  • Log in
  • My Cart
Advertisement
American Society of Nephrology

Advanced Search

  • Home
  • Content
    • Published Ahead of Print
    • Current Issue
    • Subject Collections
    • JASN Podcasts
    • Archives
    • Saved Searches
    • ASN Meeting Abstracts
  • Authors
    • Submit a Manuscript
    • Author Resources
  • Editorial Team
  • Subscriptions
  • More
    • About JASN
    • Alerts
    • Advertising
    • Editorial Fellowship Program
    • Feedback
    • Reprints
    • Impact Factor
  • ASN Kidney News
  • Follow JASN on Twitter
  • Visit ASN on Facebook
  • Follow JASN on RSS
  • Community Forum

About the Cover

November 2014; Volume 25,Issue 11

Cover image

Genome-wide association studies (GWAS) of CKD, just like renal tissue gene expression profiling studies, only capture one layer of the underlying pathophysiology of CKD. Integrating the knowledge of both, genetic and transcriptomic associations with renal function impairment can identify key drivers for CKD. Using this approach, CKD-associated molecular pathways are identified and displayed here as individual hubs or nodes. CKD-pathways are connected with each other via lines that represent co-regulated transcripts of CKD candidate genes identified by GWAS. Nodes have been colored according to six main classes of pathways derived from the Kyoto Encyclopedia of Genes and Genomes, highlighting in a global view the key drivers of CKD. Matthias Kretzler, University of Michigan Medical Center

Back to top
PreviousNext

In this issue

Journal of the American Society of Nephrology: 25 (11)
Journal of the American Society of Nephrology
Vol. 25, Issue 11
November 2014
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author

Issue highlights

  • Protective role of Mafb in diabetic nephropathy
  • CMV-responsive γδT cells and antibody-mediated kidney allograft dysfunction
  • Vasculopathic effects of HDL in CKD
  • Barriers to chronic dialysis
Sign up for alerts
View Selected Citations (0)

Jump to

  • This Month’s Highlights
  • Up Front Matters
    • Editorials
    • Brief Reviews
    • Clinical Commentary
  • Brief Communications
  • Basic Research
  • Clinical Epidemiology
  • Clinical Research
  • Most Read
Loading
  • Remdesivir in Patients with Acute or Chronic Kidney Disease and COVID-19
  • COVID-19–Associated Glomerular Disease
  • COVID-19 Infection in Kidney Transplant Recipients: Disease Incidence and Clinical Outcomes
  • Caution in Identifying Coronaviruses by Electron Microscopy
  • AKI in Hospitalized Patients with COVID-19
More...

Articles

  • Current Issue
  • Early Access
  • Subject Collections
  • Article Archive
  • ASN Annual Meeting Abstracts

Information for Authors

  • Submit a Manuscript
  • Author Resources
  • Editorial Fellowship Program
  • ASN Journal Policies
  • Reuse/Reprint Policy

About

  • JASN
  • ASN
  • ASN Journals
  • ASN Kidney News

Journal Information

  • About JASN
  • JASN Email Alerts
  • JASN Key Impact Information
  • JASN Podcasts
  • JASN RSS Feeds
  • Editorial Board

More Information

  • Advertise
  • ASN Podcasts
  • ASN Publications
  • Become an ASN Member
  • Feedback
  • Follow on Twitter
  • Password/Email Address Changes
  • Subscribe

© 2021 American Society of Nephrology

Print ISSN - 1046-6673 Online ISSN - 1533-3450

Powered by HighWire