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About the Cover

June 2014; Volume 25,Issue 6

Cover image

In Ctns proximal tubular cells (identified by apical megalin, in magenta; note decreased expression by the disease), lysosomes (defined by LAMP-1, red) show enlargement (small arrows) then distortion by crystals (arrowheads). Enlarged lysosomes accumulate the endocytic tracer (injected peroxidase, green), then progressively disconnect from active endocytic trafficking (i.e. become residual bodies) and can discharge their content into the tubular lumen (i.e. lysosomal defecation). Héloïse P. Gaide Chevronnay, De Duve Institute, Brussels Belgium

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Journal of the American Society of Nephrology: 25 (6)
Journal of the American Society of Nephrology
Vol. 25, Issue 6
June 2014
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Issue highlights

  • Generating renal tubules from human pluripotent stem cells
  • Angiopoietin-2 and arterial stiffness in CKD
  • Skeletal effects of steroid withdrawal in transplantation
  • Sulfur and cardiovascular risk profile in transplantation
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Print ISSN - 1046-6673 Online ISSN - 1533-3450

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