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Up Front MattersSpecial Article
Open Access

Successful Delivery of RRT in Ebola Virus Disease

Michael J. Connor, Colleen Kraft, Aneesh K. Mehta, Jay B. Varkey, G. Marshall Lyon, Ian Crozier, Ute Ströher, Bruce S. Ribner and Harold A. Franch
JASN January 2015, 26 (1) 31-37; DOI: https://doi.org/10.1681/ASN.2014111057
Michael J. Connor Jr
Divisions of *Pulmonary, Allergy, and Critical Care,
†Renal Medicine, and
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Colleen Kraft
‡Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia;
§Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia;
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Aneesh K. Mehta
‡Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia;
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Jay B. Varkey
‡Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia;
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G. Marshall Lyon
‡Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia;
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Ian Crozier
‖Infectious Diseases Institute, Mulago Hospital Complex, Kampala, Uganda;
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Ute Ströher
¶US Centers for Disease Control and Prevention, Atlanta, Georgia; and
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Bruce S. Ribner
‡Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia;
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Harold A. Franch
†Renal Medicine, and
**Research Service, Atlanta Department of Veterans Affairs Medical Center, Decatur, Georgia
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Abstract

AKI has been observed in cases of Ebola virus disease. We describe the protocol for the first known successful delivery of RRT with subsequent renal recovery in a patient with Ebola virus disease treated at Emory University Hospital, in Atlanta, Georgia. Providing RRT in Ebola virus disease is complex and requires meticulous attention to safety for the patient, healthcare workers, and the community. We specifically describe measures to decrease the risk of transmission of Ebola virus disease and report pilot data demonstrating no detectable Ebola virus genetic material in the spent RRT effluent waste. This article also proposes clinical practice guidelines for acute RRT in Ebola virus disease.

  • Ebola virus disease
  • AKI
  • continuous RRT
  • biocontainment isolation
  • Copyright © 2015 by the American Society of Nephrology

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Journal of the American Society of Nephrology: 26 (1)
Journal of the American Society of Nephrology
Vol. 26, Issue 1
January 2015
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Successful Delivery of RRT in Ebola Virus Disease
Michael J. Connor, Colleen Kraft, Aneesh K. Mehta, Jay B. Varkey, G. Marshall Lyon, Ian Crozier, Ute Ströher, Bruce S. Ribner, Harold A. Franch
JASN Jan 2015, 26 (1) 31-37; DOI: 10.1681/ASN.2014111057

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Successful Delivery of RRT in Ebola Virus Disease
Michael J. Connor, Colleen Kraft, Aneesh K. Mehta, Jay B. Varkey, G. Marshall Lyon, Ian Crozier, Ute Ströher, Bruce S. Ribner, Harold A. Franch
JASN Jan 2015, 26 (1) 31-37; DOI: 10.1681/ASN.2014111057
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  • Balancing the Duty to Treat Patients with Ebola Virus Disease with the Risks to Dialysis Personnel
  • Tackling emerging infections: clinical and public health lessons from the West African Ebola virus disease outbreak, 2014-2015
  • Backs against the Wall: Novel and Existing Strategies Used during the 2014-2015 Ebola Virus Outbreak
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Keywords

  • Ebola virus disease
  • AKI
  • continuous RRT
  • biocontainment isolation

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