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Clinical Research
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The Clinical and Economic Effect of Vascular Access Selection in Patients Initiating Hemodialysis with a Catheter

Alian Al-Balas, Timmy Lee, Carlton J. Young, Jeffrey A. Kepes, Jill Barker-Finkel and Michael Allon
JASN December 2017, 28 (12) 3679-3687; DOI: https://doi.org/10.1681/ASN.2016060707
Alian Al-Balas
Divisions of *Nephrology and
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Timmy Lee
Divisions of *Nephrology and
†Division of Nephrology, Veterans Affairs Medical Center, Birmingham, Alabama
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Carlton J. Young
‡Transplant Surgery, University of Alabama at Birmingham, Birmingham, Alabama; and
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Jeffrey A. Kepes
Divisions of *Nephrology and
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Jill Barker-Finkel
Divisions of *Nephrology and
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Michael Allon
Divisions of *Nephrology and
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Abstract

Patients in the United States frequently initiate hemodialysis with a central venous catheter (CVC) and subsequently undergo placement of a new arteriovenous fistula (AVF) or arteriovenous graft (AVG). Little is known about the clinical and economic effects of initial vascular access choice. We identified 479 patients starting hemodialysis with a CVC at a large medical center (during 2004–2012) who subsequently had an AVF (n=295) or AVG (n=105) placed or no arteriovenous access (CVC group, n=71). Compared with patients receiving an AVG, those receiving an AVF had more frequent surgical access procedures per year (1.01 [95% confidence interval, 0.95 to 1.08] versus 0.62 [95% confidence interval, 0.55 to 0.70]; P<0.001) but a similar frequency of percutaneous access procedures per year. Patients receiving an AVF had a higher median annual cost (interquartile range) of surgical access procedures than those receiving an AVG ($4857 [$2523–$8835] versus $2819 [$1411–$4274]; P<0.001), whereas the annual cost of percutaneous access procedures was similar in both groups. The AVF group had a higher median overall annual access-related cost than the AVG group ($10,642 [$5406–$19,878] versus $6810 [$3718–$13,651]; P=0.001) after controlling for patient age, sex, race, and diabetes. The CVC group had the highest median annual overall access-related cost ($28,709 [$11,793–$66,917]; P<0.001), largely attributable to the high frequency of hospitalizations due to catheter-related bacteremia. In conclusion, among patients initiating hemodialysis with a CVC, the annual cost of access-related procedures and complications is higher in patients who initially receive an AVF versus an AVG.

  • arteriovenous access
  • arteriovenous fistula
  • arteriovenous graft
  • Copyright © 2017 by the American Society of Nephrology
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Journal of the American Society of Nephrology: 28 (12)
Journal of the American Society of Nephrology
Vol. 28, Issue 12
December 2017
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The Clinical and Economic Effect of Vascular Access Selection in Patients Initiating Hemodialysis with a Catheter
Alian Al-Balas, Timmy Lee, Carlton J. Young, Jeffrey A. Kepes, Jill Barker-Finkel, Michael Allon
JASN Dec 2017, 28 (12) 3679-3687; DOI: 10.1681/ASN.2016060707

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The Clinical and Economic Effect of Vascular Access Selection in Patients Initiating Hemodialysis with a Catheter
Alian Al-Balas, Timmy Lee, Carlton J. Young, Jeffrey A. Kepes, Jill Barker-Finkel, Michael Allon
JASN Dec 2017, 28 (12) 3679-3687; DOI: 10.1681/ASN.2016060707
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