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Table of Contents

February 2018; Volume 29,Issue 2

Looking for COVID information? All ASN Journal COVID articles are in the COVID-19 Research Collection or the COVID-19 In Context Collection. All articles are free.​

This Month’s Highlights

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    This Month’s Highlights
    JASN February 2018, 29 (2) i; DOI: https://doi.org/10.1681/ASN.2017121324
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Up Front Matters

  • Editorials

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      Insights into the Regulation of Collecting Duct Homeostasis by Small Noncoding RNAs
      Yu Leng Phua and Jacqueline Ho
      JASN February 2018, 29 (2) 349-350; DOI: https://doi.org/10.1681/ASN.2017101072
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      Any Progress in the Treatment of Antibody-Mediated Rejection?
      Klemens Budde and Michael Dürr
      JASN February 2018, 29 (2) 350-352; DOI: https://doi.org/10.1681/ASN.2017121296
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      Making the Right Decision: Do Clinical Decision Support Systems for AKI Improve Patient Outcomes?
      Nicholas M. Selby and Richard J. Fluck
      JASN February 2018, 29 (2) 352-354; DOI: https://doi.org/10.1681/ASN.2017121284
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      Banff Classification of Polyomavirus Nephropathy: A New Tool for Research and Clinical Practice
      Jeffrey B. Kopp
      JASN February 2018, 29 (2) 354-355; DOI: https://doi.org/10.1681/ASN.2017121328
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      Editorial Note: From Both Sides Now
      Josephine P. Briggs and Thomas H. Hostetter
      JASN February 2018, 29 (2) 355-356; DOI: https://doi.org/10.1681/ASN.2017121322
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  • Perspectives

    • Open Access
      Should We Increase GFR with Bardoxolone in Alport Syndrome?
      Colin Baigent and Rachel Lennon
      JASN February 2018, 29 (2) 357-359; DOI: https://doi.org/10.1681/ASN.2017101062
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    • Open Access
      Bardoxolone—the Phoenix?
      Robert D. Toto
      JASN February 2018, 29 (2) 360-361; DOI: https://doi.org/10.1681/ASN.2017121317
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  • Brief Reviews

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      Clinical Translation of Mesenchymal Stromal Cell Therapies in Nephrology
      Norberto Perico, Federica Casiraghi and Giuseppe Remuzzi
      JASN February 2018, 29 (2) 362-375; DOI: https://doi.org/10.1681/ASN.2017070781
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      Metabolic Acidosis and Subclinical Metabolic Acidosis in CKD
      Kalani L. Raphael
      JASN February 2018, 29 (2) 376-382; DOI: https://doi.org/10.1681/ASN.2017040422
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      BP Measurement in Clinical Practice: Time to SPRINT to Guideline-Recommended Protocols
      Paul E. Drawz and Joachim H. Ix
      JASN February 2018, 29 (2) 383-388; DOI: https://doi.org/10.1681/ASN.2017070753
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      Tissue-Resident Lymphocytes in the Kidney
      Jan-Eric Turner, Martina Becker, Hans-Willi Mittrücker and Ulf Panzer
      JASN February 2018, 29 (2) 389-399; DOI: https://doi.org/10.1681/ASN.2017060599
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Brief Communications

  • Phospholipase A2 Receptor 1 Epitope Spreading at Baseline Predicts Reduced Likelihood of Remission of Membranous Nephropathy
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    Phospholipase A2 Receptor 1 Epitope Spreading at Baseline Predicts Reduced Likelihood of Remission of Membranous Nephropathy
    Barbara Seitz-Polski, Hanna Debiec, Alexandra Rousseau, Karine Dahan, Christelle Zaghrini, Christine Payré, Vincent L.M. Esnault, Gérard Lambeau and Pierre Ronco
    JASN February 2018, 29 (2) 401-408; DOI: https://doi.org/10.1681/ASN.2017070734
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    TRPC5 Does Not Cause or Aggravate Glomerular Disease
    Xuexiang Wang, Ranadheer R. Dande, Hao Yu, Beata Samelko, Rachel E. Miller, Mehmet M. Altintas and Jochen Reiser
    JASN February 2018, 29 (2) 409-415; DOI: https://doi.org/10.1681/ASN.2017060682
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  • Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function
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    Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function
    Bing Guo, Qing Lyu, Orazio J. Slivano, Ronald Dirkx, Christine K. Christie, Jan Czyzyk, Aram F. Hezel, Ali G. Gharavi, Eric M. Small and Joseph M. Miano
    JASN February 2018, 29 (2) 416-422; DOI: https://doi.org/10.1681/ASN.2017050473
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Basic Research

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    Intragraft Molecular Pathways Associated with Tolerance Induction in Renal Transplantation
    Lorenzo Gallon, James M. Mathew, Sai Vineela Bontha, Catherine I. Dumur, Pranav Dalal, Lakshmi Nadimpalli, Daniel G. Maluf, Aneesha A. Shetty, Suzanne T. Ildstad, Joseph R. Leventhal and Valeria R. Mas
    JASN February 2018, 29 (2) 423-433; DOI: https://doi.org/10.1681/ASN.2017030348
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  • Modulation of Renal GLUT2 by the Cannabinoid-1 Receptor: Implications for the Treatment of Diabetic Nephropathy
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    Modulation of Renal GLUT2 by the Cannabinoid-1 Receptor: Implications for the Treatment of Diabetic Nephropathy
    Liad Hinden, Shiran Udi, Adi Drori, Asaad Gammal, Alina Nemirovski, Rivka Hadar, Saja Baraghithy, Anna Permyakova, Matan Geron, Merav Cohen, Sabina Tsytkin-Kirschenzweig, Yael Riahi, Gil Leibowitz, Yaakov Nahmias, Avi Priel and Joseph Tam
    JASN February 2018, 29 (2) 434-448; DOI: https://doi.org/10.1681/ASN.2017040371
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  • MicroRNA-709 Mediates Acute Tubular Injury through Effects on Mitochondrial Function
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    MicroRNA-709 Mediates Acute Tubular Injury through Effects on Mitochondrial Function
    Yan Guo, Jiajia Ni, Shuang Chen, Mi Bai, Jiajuan Lin, Guixia Ding, Yue Zhang, Pingping Sun, Zhanjun Jia, Songming Huang, Li Yang and Aihua Zhang
    JASN February 2018, 29 (2) 449-461; DOI: https://doi.org/10.1681/ASN.2017040381
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  • Chromatin Conformation Links Distal Target Genes to CKD Loci
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    Chromatin Conformation Links Distal Target Genes to CKD Loci
    Maarten M. Brandt, Claartje A. Meddens, Laura Louzao-Martinez, Noortje A.M. van den Dungen, Nico R. Lansu, Edward E.S. Nieuwenhuis, Dirk J. Duncker, Marianne C. Verhaar, Jaap A. Joles, Michal Mokry and Caroline Cheng
    JASN February 2018, 29 (2) 462-476; DOI: https://doi.org/10.1681/ASN.2016080875
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    Progressive Renal Disease Established by Renin-Coding Adeno-Associated Virus–Driven Hypertension in Diverse Diabetic Models
    Shannon M. Harlan, Kathleen M. Heinz-Taheny, John M. Sullivan, Tao Wei, Hana E. Baker, Dianna L. Jaqua, Zhonghua Qi, Martin S. Cramer, Tatiyana L. Shiyanova, Matthew D. Breyer and Josef G. Heuer
    JASN February 2018, 29 (2) 477-491; DOI: https://doi.org/10.1681/ASN.2017040385
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  • Tonicity-Responsive Enhancer-Binding Protein Mediates Hyperglycemia-Induced Inflammation and Vascular and Renal Injury
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    Tonicity-Responsive Enhancer-Binding Protein Mediates Hyperglycemia-Induced Inflammation and Vascular and Renal Injury
    Soo Youn Choi, Sun Woo Lim, Shabnam Salimi, Eun Jin Yoo, Whaseon Lee-Kwon, Hwan Hee Lee, Jun Ho Lee, Braxton D. Mitchell, Satoru Sanada, Afshin Parsa and Hyug Moo Kwon
    JASN February 2018, 29 (2) 492-504; DOI: https://doi.org/10.1681/ASN.2017070718
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  • Reduced Expression of Glutathione S-Transferase <strong><em>α</em></strong>4 Promotes Vascular Neointimal Hyperplasia in CKD
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    Reduced Expression of Glutathione S-Transferase α4 Promotes Vascular Neointimal Hyperplasia in CKD
    Jinlong Luo, Guang Chen, Ming Liang, Aini Xie, Qingtian Li, Qunying Guo, Rajendra Sharma and Jizhong Cheng
    JASN February 2018, 29 (2) 505-517; DOI: https://doi.org/10.1681/ASN.2017030290
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  • Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis
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    Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis
    Sachin Hajarnis, Matanel Yheskel, Darren Williams, Thomas Brefort, Bob Glaudemans, Huguette Debaix, Michel Baum, Olivier Devuyst and Vishal Patel
    JASN February 2018, 29 (2) 518-531; DOI: https://doi.org/10.1681/ASN.2017030334
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  • Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction Obstruction
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    Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction Obstruction
    Sepideh Sheybani-Deloui, Lijun Chi, Marian V. Staite, Jason E. Cain, Brian J. Nieman, R. Mark Henkelman, Brandon J. Wainwright, S. Steven Potter, Darius J. Bagli, Armando J. Lorenzo and Norman D. Rosenblum
    JASN February 2018, 29 (2) 532-544; DOI: https://doi.org/10.1681/ASN.2017050482
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  • Extracellular Adenosine Stimulates Vacuolar ATPase–Dependent Proton Secretion in Medullary Intercalated Cells
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    Extracellular Adenosine Stimulates Vacuolar ATPase–Dependent Proton Secretion in Medullary Intercalated Cells
    Maria A. Battistone, Anil V. Nair, Claire R. Barton, Rachel N. Liberman, Maria A. Peralta, Diane E. Capen, Dennis Brown and Sylvie Breton
    JASN February 2018, 29 (2) 545-556; DOI: https://doi.org/10.1681/ASN.2017060643
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  • Redirecting TGF-<em>β</em> Signaling through the <em>β</em>-Catenin/Foxo Complex Prevents Kidney Fibrosis
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    Redirecting TGF-β Signaling through the β-Catenin/Foxo Complex Prevents Kidney Fibrosis
    Xi Qiao, Padmashree Rao, Yun Zhang, Lixin Liu, Min Pang, Hailong Wang, Min Hu, Xinrui Tian, Jianlin Zhang, Ye Zhao, Xin Maggie Wang, Chengshi Wang, Hong Yu, Fei Guo, Qi Cao, Yiping Wang, Yuan Min Wang, Geoff Yu Zhang, Vincent W. Lee, Stephen I. Alexander, Guoping Zheng and David C.H. Harris
    JASN February 2018, 29 (2) 557-570; DOI: https://doi.org/10.1681/ASN.2016121362
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Clinical Epidemiology

  • Overweight and Obesity Are Predictors of Progression in Early Autosomal Dominant Polycystic Kidney Disease
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    Overweight and Obesity Are Predictors of Progression in Early Autosomal Dominant Polycystic Kidney Disease
    Kristen L. Nowak, Zhiying You, Berenice Gitomer, Godela Brosnahan, Vicente E. Torres, Arlene B. Chapman, Ronald D. Perrone, Theodore I. Steinman, Kaleab Z. Abebe, Frederic F. Rahbari-Oskoui, Alan S.L. Yu, Peter C. Harris, Kyongtae T. Bae, Marie Hogan, Dana Miskulin and Michel Chonchol
    JASN February 2018, 29 (2) 571-578; DOI: https://doi.org/10.1681/ASN.2017070819
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  • Longitudinal FGF23 Trajectories and Mortality in Patients with CKD
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    Longitudinal FGF23 Trajectories and Mortality in Patients with CKD
    Tamara Isakova, Xuan Cai, Jungwha Lee, Dawei Xie, Xue Wang, Rupal Mehta, Norrina B. Allen, Julia J. Scialla, Michael J. Pencina, Amanda H. Anderson, John Talierco, Jing Chen, Michael J. Fischer, Susan P. Steigerwalt, Mary B. Leonard, Chi-yuan Hsu, Ian H. de Boer, John W. Kusek, Harold I. Feldman and Myles Wolf; on behalf of Chronic Renal Insufficiency Cohort (CRIC) Study Investigators
    JASN February 2018, 29 (2) 579-590; DOI: https://doi.org/10.1681/ASN.2017070772
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Clinical Research

  • A Randomized Trial of Bortezomib in Late Antibody-Mediated Kidney Transplant Rejection
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    A Randomized Trial of Bortezomib in Late Antibody-Mediated Kidney Transplant Rejection
    Farsad Eskandary, Heinz Regele, Lukas Baumann, Gregor Bond, Nicolas Kozakowski, Markus Wahrmann, Luis G. Hidalgo, Helmuth Haslacher, Christopher C. Kaltenecker, Marie-Bernadette Aretin, Rainer Oberbauer, Martin Posch, Anton Staudenherz, Ammon Handisurya, Jeff Reeve, Philip F. Halloran and Georg A. Böhmig
    JASN February 2018, 29 (2) 591-605; DOI: https://doi.org/10.1681/ASN.2017070818
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  • Dynamic Prognostic Score to Predict Kidney Allograft Survival in Patients with Antibody-Mediated Rejection
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    Dynamic Prognostic Score to Predict Kidney Allograft Survival in Patients with Antibody-Mediated Rejection
    Denis Viglietti, Alexandre Loupy, Olivier Aubert, Oriol Bestard, Jean-Paul Duong Van Huyen, Jean-Luc Taupin, Denis Glotz, Christophe Legendre, Xavier Jouven, Michel Delahousse, Nassim Kamar and Carmen Lefaucheur
    JASN February 2018, 29 (2) 606-619; DOI: https://doi.org/10.1681/ASN.2017070749
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  • Complement-Activating Anti-HLA Antibodies in Kidney Transplantation: Allograft Gene Expression Profiling and Response to Treatment
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    Complement-Activating Anti-HLA Antibodies in Kidney Transplantation: Allograft Gene Expression Profiling and Response to Treatment
    Carmen Lefaucheur, Denis Viglietti, Luis G. Hidalgo, Lloyd E. Ratner, Serena M. Bagnasco, Ibrahim Batal, Olivier Aubert, Babak J. Orandi, Federico Oppenheimer, Oriol Bestard, Paolo Rigotti, Anna V. Reisaeter, Nassim Kamar, Yvon Lebranchu, Jean-Paul Duong Van Huyen, Patrick Bruneval, Denis Glotz, Christophe Legendre, Jean-Philippe Empana, Xavier Jouven, Dorry L. Segev, Robert A. Montgomery, Adriana Zeevi, Philip F. Halloran and Alexandre Loupy
    JASN February 2018, 29 (2) 620-635; DOI: https://doi.org/10.1681/ASN.2017050589
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  • Renal Dysfunction Influences the Diagnostic and Prognostic Performance of High-Sensitivity Cardiac Troponin I
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    Renal Dysfunction Influences the Diagnostic and Prognostic Performance of High-Sensitivity Cardiac Troponin I
    Ian Gunsolus, Yader Sandoval, Stephen W. Smith, Anne Sexter, Karen Schulz, Charles A. Herzog and Fred S. Apple
    JASN February 2018, 29 (2) 636-643; DOI: https://doi.org/10.1681/ASN.2017030341
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  • LDL Receptor-Related Protein 2 (Megalin) as a Target Antigen in Human Kidney Anti-Brush Border Antibody Disease
    Open Access
    LDL Receptor-Related Protein 2 (Megalin) as a Target Antigen in Human Kidney Anti-Brush Border Antibody Disease
    Christopher P. Larsen, Claire Trivin-Avillach, Paige Coles, A. Bernard Collins, Michael Merchant, Hong Ma, Daniel W. Wilkey, Josephine M. Ambruzs, Nidia C. Messias, L. Nicholas Cossey, Ivy A. Rosales, Thomas Wooldridge, Patrick D. Walker, Robert B. Colvin, Jon Klein, David J. Salant and Laurence H. Beck
    JASN February 2018, 29 (2) 644-653; DOI: https://doi.org/10.1681/ASN.2017060664
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  • Clinical Decision Support for In-Hospital AKI
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    Clinical Decision Support for In-Hospital AKI
    Mohammed Al-Jaghbeer, Dilhari Dealmeida, Andrew Bilderback, Richard Ambrosino and John A. Kellum
    JASN February 2018, 29 (2) 654-660; DOI: https://doi.org/10.1681/ASN.2017070765
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  • Deletion Variants of <em>CFHR1</em> and <em>CFHR3</em> Associate with Mesangial Immune Deposits but Not with Progression of IgA Nephropathy
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    Deletion Variants of CFHR1 and CFHR3 Associate with Mesangial Immune Deposits but Not with Progression of IgA Nephropathy
    Perrine Jullien, Blandine Laurent, Guillaume Claisse, Ingrid Masson, Miriana Dinic, Damien Thibaudin, Francois Berthoux, Eric Alamartine, Christophe Mariat and Nicolas Maillard
    JASN February 2018, 29 (2) 661-669; DOI: https://doi.org/10.1681/ASN.2017010019
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  • Perioperative THR-184 and AKI after Cardiac Surgery
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    Perioperative THR-184 and AKI after Cardiac Surgery
    Jonathan Himmelfarb, Glenn M. Chertow, Peter A. McCullough, Thierry Mesana, Andrew D. Shaw, Thoralf M. Sundt, Craig Brown, David Cortville, François Dagenais, Benoit de Varennes, Manuel Fontes, Jerome Rossert and Jean-Claude Tardif
    JASN February 2018, 29 (2) 670-679; DOI: https://doi.org/10.1681/ASN.2017020217
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    The Banff Working Group Classification of Definitive Polyomavirus Nephropathy: Morphologic Definitions and Clinical Correlations
    Volker Nickeleit, Harsharan K. Singh, Parmjeet Randhawa, Cinthia B. Drachenberg, Ramneesh Bhatnagar, Erika Bracamonte, Anthony Chang, W. James Chon, Darshana Dadhania, Vicki G. Davis, Helmut Hopfer, Michael J. Mihatsch, John C. Papadimitriou, Stefan Schaub, Michael B. Stokes, Mohammad F. Tungekar and Surya V. Seshan; on behalf of the Banff Working Group on Polyomavirus Nephropathy
    JASN February 2018, 29 (2) 680-693; DOI: https://doi.org/10.1681/ASN.2017050477
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    Segmental Sclerosis and Extracapillary Hypercellularity Predict Diabetic ESRD
    Amy K. Mottl, Adil Gasim, Fernanda Payan Schober, Yichun Hu, Askia K. Dunnon, Susan L. Hogan and J. Charles Jennette
    JASN February 2018, 29 (2) 694-703; DOI: https://doi.org/10.1681/ASN.2017020192
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Erratum

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    Erratum
    JASN February 2018, 29 (2) 704; DOI: https://doi.org/10.1681/ASN.2017091022
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In this issue

Journal of the American Society of Nephrology: 29 (2)
Journal of the American Society of Nephrology
Vol. 29, Issue 2
February 2018
  • Table of Contents
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Issue highlights

  • Should We Increase GFR with Bardoxolone in Alport Syndrome?
  • A Randomized Trial of Bortezomib in Late Antibody-Mediated Kidney Transplant Rejection
  • Clinical Decision Support for In-Hospital AKI
  • Overweight and Obesity Are Predictors of Progression in Early Autosomal Dominant Polycystic Kidney Disease
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  • Effects of Dapagliflozin in Stage 4 Chronic Kidney Disease
  • Calcium-Based Phosphate Binders and Plasma Oxalate Concentration in Dialysis Patients
  • A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease
  • Enabling Patient Choice: The “Deciding Not to Decide” Option for Older Adults Facing Dialysis Decisions
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