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Therapeutic Inhibition of VEGF Signaling and Associated Nephrotoxicities

Chelsea C. Estrada, Alejandro Maldonado and Sandeep K. Mallipattu
JASN February 2019, 30 (2) 187-200; DOI: https://doi.org/10.1681/ASN.2018080853
Chelsea C. Estrada
1Division of Nephrology, Department of Medicine, Stony Brook University, Stony Brook, New York; and
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Alejandro Maldonado
1Division of Nephrology, Department of Medicine, Stony Brook University, Stony Brook, New York; and
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Sandeep K. Mallipattu
1Division of Nephrology, Department of Medicine, Stony Brook University, Stony Brook, New York; and
2Renal Section, Northport Veterans Affairs Medical Center, Northport, New York
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Article Information

vol. 30 no. 2 187-200
DOI 
https://doi.org/10.1681/ASN.2018080853
PubMed 
30642877

Published By 
American Society of Nephrology
Print ISSN 
1046-6673
Online ISSN 
1533-3450
History 
  • Published online January 31, 2019.

Article Versions

  • Earlier version (January 14, 2019 - 08:13).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2019 by the American Society of Nephrology

Author Information

  1. Chelsea C. Estrada1,
  2. Alejandro Maldonado1 and
  3. Sandeep K. Mallipattu1,2
  1. 1Division of Nephrology, Department of Medicine, Stony Brook University, Stony Brook, New York; and
  2. 2Renal Section, Northport Veterans Affairs Medical Center, Northport, New York
  1. Correspondence:
    Dr. Sandeep K. Mallipattu, Department of Medicine/Nephrology, Stony Brook University, 100 Nicolls Road, HSCT16-80E, Stony Brook, NY 11794-8176. Email: sandeep.mallipattu{at}stonybrookmedicine.edu

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Journal of the American Society of Nephrology: 30 (2)
Journal of the American Society of Nephrology
Vol. 30, Issue 2
February 2019
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Therapeutic Inhibition of VEGF Signaling and Associated Nephrotoxicities
Chelsea C. Estrada, Alejandro Maldonado, Sandeep K. Mallipattu
JASN Feb 2019, 30 (2) 187-200; DOI: 10.1681/ASN.2018080853

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Therapeutic Inhibition of VEGF Signaling and Associated Nephrotoxicities
Chelsea C. Estrada, Alejandro Maldonado, Sandeep K. Mallipattu
JASN Feb 2019, 30 (2) 187-200; DOI: 10.1681/ASN.2018080853
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Jump to section

  • Article
    • Abstract
    • VEGF Signaling in the Kidney
    • Therapeutic VEGF Inhibition
    • Anti-VEGF mAb
    • VEGF Signaling Pathways
    • RAF/MAPK/ERK Signaling
    • eNOS Signaling
    • mTOR Signaling
    • Clinical Considerations for Minimizing Nephrotoxicity
    • Conclusions and Future Perspectives
    • Disclosures
    • Acknowledgments
    • Footnotes
    • References
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More in this TOC Section

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Keywords

  • signaling
  • nitric oxide
  • VEGF
  • proteinuria
  • hypertension

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