On the cover: Translational profiling of proximal tubule during unilateral ureteral obstruction reveals sexually dimorphic gene expression both at baseline and after injury. The heatmap depicts male gene expression (left three colums) compared to female gene expression (right three columns) at baseline, day 5 and day 10 of unilateral ureteral obstruction. Image supplied by Dr. Benjamin D. Humphreys, Division of Nephrology, Washington University, St. Louis, Missouri