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Letters to the Editor
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Authors’ Reply

Alan Kliger
JASN October 2020, 31 (10) 2492-2493; DOI: https://doi.org/10.1681/ASN.2020071089
Alan Kliger
Department of Medicine, Yale University School of Medicine, New Haven, Connecticut
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  • rationing

We agree that there are limitations to the use of Sequential Organ Failure Assessment (SOFA) scores for stratification of mortality risk of patients with CKD and ESKD.1 Using a single creatinine (or daily urine volume) measurement to assess the kidney function of patients with CKD is one of many limitations of SOFA scores, as is the lack of differentiation in the SOFA score between acute kidney disease and CKD. We agree that these limitations are particularly important when used to compare one individual with another for possible resource prioritization, and acknowledge that the SOFA score, along with virtually all other severity of illness scores, tends to overestimate mortality risk of patients with advanced CKD. Nevertheless, while recognizing these caveats, we believe that the SOFA score is still helpful to objectively assess patients with complex illness, but agree with Dr. Sanghavi2 that even better methods to assess mortality risk are needed to optimize equitable allocation of resources in the setting of scarcity.

Disclosures

The author has nothing to disclose.

Funding

None.

Footnotes

  • Published online ahead of print. Publication date available at www.jasn.org.

  • See related Letters to the Editor, “Critically Ill Patients with CKD Deserve Better Mortality Prediction Scores,” on page 2492.

  • Copyright © 2020 by the American Society of Nephrology

References

  1. ↵
    1. Silberzweig J,
    2. Ikizler TA,
    3. Kramer H,
    4. Palevsky PM,
    5. Vassalotti J,
    6. Kliger AS
    : Rationing scarce resources: The potential impact of COVID-19 on patients with chronic kidney disease. J Am Soc Nephrol 31: 1926–1928, 2020
    OpenUrlFREE Full Text
  2. ↵
    1. Sanghavi S
    : Critically ill patients with CKD deserve better mortality prediction scores. J Am Soc Nephrol 31: 2492, 2020
    OpenUrlFREE Full Text
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Journal of the American Society of Nephrology: 31 (10)
Journal of the American Society of Nephrology
Vol. 31, Issue 10
October 2020
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Authors’ Reply
Alan Kliger
JASN Oct 2020, 31 (10) 2492-2493; DOI: 10.1681/ASN.2020071089

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Authors’ Reply
Alan Kliger
JASN Oct 2020, 31 (10) 2492-2493; DOI: 10.1681/ASN.2020071089
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  • Remdesivir in COVID-19 Patients with Impaired Renal Function
  • Post-Mortem Diagnostics in COVID-19 AKI, More Often but Timely
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