On the cover: scRNAseq Identifies Novel Epithelial-to-Stromal Interactions in the Adult AKI. (A) Circos Plot of ligand-receptor interactions between the proximal (brown) and distal (blue) tubules, the stromal cells (green), and the stromal/pericyte cells (purple) in the normal kidney. The directions of predicted ligand-receptor interactions are shown with the sharp ends of the arrows. (B) Circos Plot of ligand-receptor interactions between the proximal tubules (brown), injured proximal tubules (red), mixed identity cells (green), distal tubules (blue) and the stromal cells (teal) in the UIR Day 4 kidney. The directions of predicted ligand-receptor interactions are shown with the sharp ends of the arrows. Black arrows show Vim-Cd44, Col18a1-Gpc4 and Col18a1-Itgb1 Ligand-Receptor pairs. Note the dramatic increase in the number of potential interactions compared to the control, using the same filters. Images supplied by S. Steven Potter, Division of Developmental Biology, Cincinnati Children’s Medical Center, Cincinnati, Ohio.