Phosphorylation of ACTN4 Leads to Podocyte Vulnerability and Proteinuric Glomerulosclerosis

1Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts

2Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts

3Department of Pathology, Boston Children’s Hospital and Harvard Medical School, Boston, Massachusetts

4F.M. Kirby Neurobiology Center, Department of Neurobiology, Boston Children’s Hospital, Boston, Massachusetts

5Biognosys AG, Schlieren, Switzerland

6Division of Nephrology and Hypertension, Oregon Health & Science University, Portland, Oregon

7Division of Experimental Medicine, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts

1Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts

8Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts

9NeuroTechnology Studio, Program for Interdisciplinary Neuroscience, Brigham and Women’s Hospital, Boston, Massachusetts

10Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts

3Department of Pathology, Boston Children’s Hospital and Harvard Medical School, Boston, Massachusetts

1Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts

1Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts

10Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts

2Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts

2Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts

2Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts

2Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts

2Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts

11Vascular Biology Program, Boston Children’s Hospital and Harvard Medical School, Boston, Massachusetts

12Department of Surgery, Boston Children’s Hospital and Harvard Medical School, Boston, Massachusetts

13Harvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, Massachusetts

3Department of Pathology, Boston Children’s Hospital and Harvard Medical School, Boston, Massachusetts

1Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts

10Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts